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UCSD Photonics 10/26/200 9 PHOTONIC SYSTEMS INTEGRATION LABORATORY UCSD JACOBS SCHOOL OF ENGINEERING Photo: Kevin Walsh, OLR University of California, San Diego Jacobs School of Engineering Design and Prototype Fabrication of a Neonatal Video Laryngoscope Katherine Baker and Joseph Ford October 15, 2009 Wade Rich and Neil Finer University of California, San Diego Medical Center

Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

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Page 1: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD Photonics

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING Photo: Kevin Walsh, OLR

University of California, San Diego

Jacobs School of Engineering

Design and Prototype Fabrication of a

Neonatal Video Laryngoscope

Katherine Baker and Joseph Ford

October 15, 2009

Wade Rich and Neil Finer

University of California, San Diego

Medical Center

Page 2: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD PhotonicsIntroduction / Motivation

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING

Dr. Neil Finer, Chief of the UCSD Medical Center’s Division of Neonatology, and

Wade Rich, Research Coordinator for the Division of Neonatology, approached

the Photonic Systems Integration Lab with a collaboration proposal.

• 25,000 extremely low birth weight infants born annually,

• Most require intubation, a difficult / traumatic process for neonates

• Current instruments designed for adults, not infants, esp. not neonates.

• Project goal: Working model of a neonatal video laryngoscope.

Page 3: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD PhotonicsInfant Intubation

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING

85 - 90% of extremely low birth weight infants need intubation.

Intubation requires 3 (average) to 10 tries

Multiple attempts lead to serious risks.

Images from Manual of Emergency Airway Management, ed. Murphy and People’s Daily Online

Page 4: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD PhotonicsLaryngoscopes

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING

Our goal was to create a working model neonatal video laryngoscope to

evaluate the feasibility of a commercial device.

Images are from Karl Storz website, GlideScope website

Traditional Laryngoscopes

GlideScope: Video Camera Karl Storz: Coherent Fiber Bundle

Video Laryngoscopes

Page 5: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD PhotonicsBlade and Device Constraints

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING

Constraints•Blade Width

•2.5mm by 6.5 mm tip

•Variable Blade Angle

•Image Quality

•Combination of Imager and Lighting

•Mechanical Properties

•Strength

•Heat

•Texture

Page 6: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD PhotonicsImager Selection

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING

We identified a promising camera in the Medigus

IntroSpicio CCD Video Camera, with a camera head

measuring only 1.8 by 1.8 by 12 mm.

Effective Focal Length .712 mm

Field of View 100°

F-number f/5.99

0

2

4

6

8

10

12

14

16

18

0 20 40 60 80

Sp

ati

al F

req

uen

cy (

in L

ine P

air

s

per

mm

)

Distance in mm

Maximum Resolvable Frequency

Given Resolution

Measured Vertical Resolution

Measured Horizontal Resolution 0

0.2

0.4

0.6

0.8

1

1.2

0 50 100 150 200

Co

ntr

ast

Spatial Frequency (Line Pairs per mm)

Modulation Transfer Function

Measured MTF for Vertical Lines

Measured MTF for Horizontal Lines

Average Measured MTF

Given MTF

Image from Medigus website

Page 7: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD PhotonicsDesign Solutions

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING

The most elegant solution is a tapered

acrylic light pipe acting as the blade.

We make use of a Fraen coupling lens.

With a necessary optical power of at least 30 to 40 mW,

an LED at the tip would dissipate far too much heat.

Calculated efficiency is just over 50%.

Image from Fraen website

Page 8: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD PhotonicsWaveguide Fabrication

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING

Acrylic blanks are cut at

the right aspect ratio.

The edges are sanded,

then flame-polished with a

hydrogen-oxygen torch.

Blanks are heated to

pliability, then stretched

to form a taper

Page 9: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD Photonics

Measured efficiency is 28%, but the LED

is bright enough that this is sufficient.

Assembly and Optical Testing of Initial Model

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING

Using an Inova X0 LED

flashlight as the handle

and light source, we

created a working model.

Ideal Backlit Target

1 cm 4 cm

LED/Waveguide Lit Target

Page 10: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD Photonics

The medical team tested the device

on a Premi-Blue Neonatal Simulator

(Gaumard).

Medical Testing and Feedback

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING

Page 11: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD PhotonicsFinal Model

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING

Page 12: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD PhotonicsFinal Model Videos

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING

Page 13: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD PhotonicsConclusions and Future Directions

• Neonate anatomy guided our design.

• We met all the constraints of the project.

• Less expensive wafer cameras could be used to reduce cost.

• We would need a sterilizable device to perform a clinical trial

• Further modifications could be made

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING

Page 14: Design and Prototype Fabrication of a UCSD Photonics ...psilab.ucsd.edu › research › Neonatal Video...PHOTONIC SYSTEMS INTEGRATION LABORATORY –UCSD JACOBS SCHOOL OF ENGINEERING

UCSD Photonics

10/26/200

9PHOTONIC SYSTEMS INTEGRATION LABORATORY – UCSD JACOBS SCHOOL OF ENGINEERING

Thank you

[email protected]