Cysts and Odontogenic Tumors4

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    Odontogenic ysts andTumorsPresented by:

    Reema Al-Shawaf

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    Introduction

    There are variety of cysts and tumors that

    affect the osseous marrow and cortex of

    the jaw bones, which are uniquelyderived

    from the tissues of developing teeth.

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    Presentation Outline

    Introduction

    Odontogenic Cysts

    Odontogenic tumors

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    Odontogenic Cysts

    A cyst is a pathologic cavity filled with

    fluid, lined by epitheliumand surrounded

    by a definite connective tissue wall.

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    Odontogenic Jaw Cysts

    Odontogenic cysts arise from tooth development

    epithelium.

    Odontogenic cysts are true cysts occurring in thejaws. They arisefrom stimulation ofepithelium

    left over from tooth development.

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    Odontogenic Jaw Cysts

    Odontogenic cysts include:

    Radicular (Apical) Cyst

    Residual cysts

    Dentigerous Cyst

    Odontogenic Keratocyst

    Lateral Periodontal cyst

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    Apical Cyst (Radicular Cyst,

    Periapical Cyst)

    A radicular cystis a cyst

    that most likely results

    when rests of epthielial

    cellsin the periodontal

    ligament are stimulated

    by inflammatory products

    from a non vital tooth.

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    Apical Cyst (Radicular Cyst,

    Periapical Cyst) Features

    It develops in apreexisting periapicalgranuloma.

    It has similar radiographicappearance as theperiapical granuloma: round or oval radiolucency

    well defined

    well corticated iflongstanding

    The adjacent teeth canbe displaced but rarelyresorbed.

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    Apical Cyst (Radicular Cyst,

    Periapical Cyst)

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    Residual Cysts

    A Residual cyst is a

    cyst that develops

    after incomplete

    removalof the originalcyst.

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    Residual Cysts

    It is a radicular cyst remaining

    after the tooth has been

    extracted.

    Usually asymptomatic. Usually

    small size (less than 1 cm in

    diameter).

    Unilocular, round or oval, well-

    defined, usually well-

    corticated.

    It can cause bone expansionand displacement of the

    adjacent teeth.

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    Dentigerous Cyst (Follicular

    Cyst) A Dentigerous cyst is

    a cyst that forms

    around the crown of

    an unerupted tooth.

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/015big.html
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    Dentigerous Cyst (Follicular Cyst)

    It arises in the follicular region ofunerupted permanent tooth.

    It develops after fluid accumulatesbetween the remnants of enamelorgan and the tooth crown.

    Usually adolescents,20-40yearsold.

    Most common sites:mandibularthird molar, maxillary canine,maxillary third molar.

    Unilocular radiolucency, well-defined, often corticated,associated with the crown of anunerupted and displaced tooth.

    Large cysts tend to expand the

    outer plate (usually buccally)

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/015big.html
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    Dentigerous Cyst (Follicular Cyst)

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/019big.htmlhttp://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/017big.htmlhttp://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/014big.htmlhttp://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/013big.html
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    Odontogenic Keratocyst(Keratocyst, Keratinizing Cyst)

    This is a non-

    inflammatory

    odontogenic cyst that

    arises from the dentallamina.

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/037big.html
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    Odontogenic Keratocyst(Keratocyst, Keratinizing Cyst)

    Features

    It is lined by keratinizing epithelium.

    It is usually located in themandible(posterior body and ramus region).

    most develop during the secondand third decade.

    It can become very large. It extendsalong the body of the mandiblecausing minimal mediolateralexpansion.

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/037big.html
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    Odontogenic Keratocyst(Keratocyst, Keratinizing Cyst)

    Features

    Unilocular (often with scallopedmargins) or multilocular (more oftenin larger lesions)

    Smooth margins, well-defined,

    often well-corticated.

    Tendency for recurrence afterinadequate surgery.

    Adjacent teeth: vital, rarelyresorbed.

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/037big.html
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    Odontogenic Keratocyst

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    Odontogenic Keratocyst

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    Odontogenic Keratocyst

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/044big.html
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    Lateral Periodontal Cyst

    Lateral Periodontal

    Cystare thought to

    arise from Epithelial

    rests in periodontumlateralto the tooth

    root.

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/062big.htmlhttp://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/061big.html
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    Lateral Periodontal Cyst

    It is a developmental odontogeniccyst. It arises from remnants of thedental lamina or from the reducedenamel epithelium.

    Common site: Along the lateral

    surface of the root of vital tooth.Usually in mandibularpremolar/canine region.

    Usually asymptomatic.

    Small size (less than 1 cm indiameter).

    Unilocular, round or oval, well-defined, usually well corticatedradiolucency.

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/062big.htmlhttp://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/061big.html
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    II. Odontogenic Tumors

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    OdontogenicTumors

    Epithelial Mixed Mesodermal

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    EpithelialOdontogenic

    Tumors

    AmeloblastomaAdenomatoidodontogenic

    tumor

    Calcifyingepithelial

    odontogenictumor

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    Ameloblastoma

    This a true neoplasm of

    odontogenic epithelium

    It is an aggressive

    neoplasm the arises from

    the remnants of the

    dental lamina and dental

    organ( odontogenic

    epithelium)

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    Ameloblastoma Benign, locally aggressive

    odontogenic tumor. Usually itslowly grows as painless swellingof the affected site.

    It can occur at any age.

    Localized invasion into thesurrounding bone.

    80-95% in the mandible (posteriorbody, ramus region). In the maxilla

    mostly in the premolar-molarregion.

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    Ameloblastoma Unilocular (small lesions).

    Multilocular (large discrete areas orhoneycomb appearance)

    Smooth, well-defined, well-corticated margins

    Adjacent teeth are often displacedand resorbed.

    It causes extensive boneexpansion.

    Incomplete removal can result inrecurrence.

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    Ameloblastoma

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/141big.htmlhttp://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/140big.html
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    Ameloblastoma

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    Adenomatoid Odontogenic Tumor

    ("Adenoameloblastoma")

    These are uncommon ,

    nonaggressive tumors of

    odontoginc epthilum.

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    Adenomatoid odontogenic tumor

    Features

    Benign. Relatively rare.

    It occurs in young patients (70% of

    cases in patients younger than 20years).

    Most common site: anterior maxilla.

    Often surrounds an entire unerupted

    tooth (most commonly the canine).

    Usually well defined, well corticated.Some tumors are totally radiolucent;others show evidence of internalclassification.

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    Calcifying epithelial odontogenic

    tumor (Pindborg tumor

    These are rare

    neoplasms of the

    toothproducingapparuts.

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    Calcifying epithelial odontogenic

    tumor (Pindborg tumor Rare benign neoplasm.

    It occurs more often in middle-

    aged patients.

    Usually in mandible.

    Small lesions may be

    radiolucent. In advanced

    stages irregularly sizedcalcifications may be scattered

    in the radiolucency.

    It can cause displacement and

    impaction of teeth.

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    MixedOdontogenic

    Tumors

    OdontomasAmeloblastic

    fibro-odontomaAmeloblastic

    fibromaAmeloblastic

    odontomaOdontomas

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    Odontomas

    It is a tumor that is

    radiogrphically and

    histologically

    characterized by theproduction of mature

    enamel , dentin ,

    cementum and pulp

    tissue . Compound # complex

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/122big.htmlhttp://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/121big.html
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    Odontoma

    Features

    Relatively common lesion.

    It usually occurs in young patients.

    Usually asymptomatic.

    Failure of eruption of a permanent toothmay be the first presenting symptom.It iscommonly found occlusal to the involved

    tooth.

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/122big.htmlhttp://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/121big.html
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    Odontoma

    Features

    Two types: complex and compoundodontoma.

    Complex odontoma is composed ofhaphazardly arranged dental hard andsoft tissues.

    Compound odontoma is composed of

    many small "denticles" .

    Well defined. The internal aspect isvery radiopaque in comparison tobone.

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/122big.htmlhttp://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/121big.html
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    Odontoma

    http://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/130big.htmlhttp://www.usc.edu/hsc/dental/PTHL312abc/312b/10/IMGs/121big.html
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    Ameloblastic fibroma

    These are benign mixed

    odontogenic tumors .

    They are characterized

    by neoplastic proliferationof maturing and early

    functional ameloblasts as

    well as the primitive

    mesnchymel componentsof the dental papilla

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    Ameloblastic fibroma

    Benign Rare. Occurs in children and

    adolescents.

    Most common site: mandible posterior

    region.

    Often associated with an unerupted

    tooth.

    Well defined, well corticated. Small

    lesions are monolocular. Large lesionsare multilocular.

    It may cause displacement of adjacent

    teeth. Large lesions cause

    buccal/lingual expansion.

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    Ameloblastic fibroma

    A l bl ti

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    Ameloblastic

    fibro-odontoma

    This is an extremely rare lesion. It consists

    of elements of ameloblastic fibroma with

    small segments of enamel and dentin.

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    MesodermalOdontogenic

    Tumors

    Odontogenicmyxoma

    (myxofibroma)

    Cemento-blastoma

    Odontogenicfibroma

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    Odontogenic myxoma (myxofibroma)

    They are benign,

    intraosseous

    neoplasms that arise

    from the

    mesenchymal portion

    of the dental papilla.

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    Odontogenic myxoma (myxofibroma)

    Features

    It represents approximately 3 - 6%of all odontogenic tumors. It ispainless and grows slowly.

    It can occur at any age but mostcommonly in the second and thirddecades of life.

    More often affect the mandible(molar/premolar region).

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    Odontogenic myxoma (myxofibroma)

    Features

    Typically multilocular (internalsepta- strings of a tennis racket orhoneycomb appearance). Largelesions can have the sun ray

    appearance of an osteosarcoma.

    Often well-defined.

    Adjacent teeth can be displacedbut rarely resorbed. It causes less

    bone expansion than in otherbenign tumors.

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    Odontogenic myxoma (myxofibroma)

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    Cementoblastoma

    This is a slow growing

    mesenchymal

    neoplasms composed

    principally ofcementum.

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    Cementoblastoma

    Features

    Benign neoplasm. Most commonlyin the second and third decade.

    Site: usually mandibular premolar

    and molar regions.

    Attached to the root of the affectedtooth. Tooth displacement,resorption are common.

    Pain in 50% of the cases,swelling.

    When radiopaque is usuallysurrounded by a thin radiolucenthalo.

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    Radiographic Features

    Location:

    Periphery:well defined RO

    with RL hallo surrounding the

    calcified mass.

    Internal structure:mixed RL-

    RO leseions may be

    amorphous

    Effect on surrounding tissues:

    expansion, external root

    resorption

    Cementoblastoma

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    Cementoblastoma

    Odontogenic

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    Odontogenic

    fibroma

    Features Rare neoplasm. More often

    between the ages 10 and 40 years.

    Asymptomatic or swelling and tooth

    mobility

    More common sites: mandible(premolar-molar region), maxilla(anterior region)

    Small lesions are usually unilocular,and larger lesions multilocular.

    Well-defined margins.

    Adjacent teeth: often displaced,impaction, root resorption.

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    Thank you