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Odontogenic ysts andTumorsPresented by:
Reema Al-Shawaf
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Introduction
There are variety of cysts and tumors that
affect the osseous marrow and cortex of
the jaw bones, which are uniquelyderived
from the tissues of developing teeth.
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Presentation Outline
Introduction
Odontogenic Cysts
Odontogenic tumors
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Odontogenic Cysts
A cyst is a pathologic cavity filled with
fluid, lined by epitheliumand surrounded
by a definite connective tissue wall.
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Odontogenic Jaw Cysts
Odontogenic cysts arise from tooth development
epithelium.
Odontogenic cysts are true cysts occurring in thejaws. They arisefrom stimulation ofepithelium
left over from tooth development.
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Odontogenic Jaw Cysts
Odontogenic cysts include:
Radicular (Apical) Cyst
Residual cysts
Dentigerous Cyst
Odontogenic Keratocyst
Lateral Periodontal cyst
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Apical Cyst (Radicular Cyst,
Periapical Cyst)
A radicular cystis a cyst
that most likely results
when rests of epthielial
cellsin the periodontal
ligament are stimulated
by inflammatory products
from a non vital tooth.
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Apical Cyst (Radicular Cyst,
Periapical Cyst) Features
It develops in apreexisting periapicalgranuloma.
It has similar radiographicappearance as theperiapical granuloma: round or oval radiolucency
well defined
well corticated iflongstanding
The adjacent teeth canbe displaced but rarelyresorbed.
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Apical Cyst (Radicular Cyst,
Periapical Cyst)
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Residual Cysts
A Residual cyst is a
cyst that develops
after incomplete
removalof the originalcyst.
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Residual Cysts
It is a radicular cyst remaining
after the tooth has been
extracted.
Usually asymptomatic. Usually
small size (less than 1 cm in
diameter).
Unilocular, round or oval, well-
defined, usually well-
corticated.
It can cause bone expansionand displacement of the
adjacent teeth.
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Dentigerous Cyst (Follicular
Cyst) A Dentigerous cyst is
a cyst that forms
around the crown of
an unerupted tooth.
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Dentigerous Cyst (Follicular Cyst)
It arises in the follicular region ofunerupted permanent tooth.
It develops after fluid accumulatesbetween the remnants of enamelorgan and the tooth crown.
Usually adolescents,20-40yearsold.
Most common sites:mandibularthird molar, maxillary canine,maxillary third molar.
Unilocular radiolucency, well-defined, often corticated,associated with the crown of anunerupted and displaced tooth.
Large cysts tend to expand the
outer plate (usually buccally)
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Dentigerous Cyst (Follicular Cyst)
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Odontogenic Keratocyst(Keratocyst, Keratinizing Cyst)
This is a non-
inflammatory
odontogenic cyst that
arises from the dentallamina.
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Odontogenic Keratocyst(Keratocyst, Keratinizing Cyst)
Features
It is lined by keratinizing epithelium.
It is usually located in themandible(posterior body and ramus region).
most develop during the secondand third decade.
It can become very large. It extendsalong the body of the mandiblecausing minimal mediolateralexpansion.
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Odontogenic Keratocyst(Keratocyst, Keratinizing Cyst)
Features
Unilocular (often with scallopedmargins) or multilocular (more oftenin larger lesions)
Smooth margins, well-defined,
often well-corticated.
Tendency for recurrence afterinadequate surgery.
Adjacent teeth: vital, rarelyresorbed.
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Odontogenic Keratocyst
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Odontogenic Keratocyst
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Odontogenic Keratocyst
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Lateral Periodontal Cyst
Lateral Periodontal
Cystare thought to
arise from Epithelial
rests in periodontumlateralto the tooth
root.
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Lateral Periodontal Cyst
It is a developmental odontogeniccyst. It arises from remnants of thedental lamina or from the reducedenamel epithelium.
Common site: Along the lateral
surface of the root of vital tooth.Usually in mandibularpremolar/canine region.
Usually asymptomatic.
Small size (less than 1 cm indiameter).
Unilocular, round or oval, well-defined, usually well corticatedradiolucency.
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II. Odontogenic Tumors
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OdontogenicTumors
Epithelial Mixed Mesodermal
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EpithelialOdontogenic
Tumors
AmeloblastomaAdenomatoidodontogenic
tumor
Calcifyingepithelial
odontogenictumor
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Ameloblastoma
This a true neoplasm of
odontogenic epithelium
It is an aggressive
neoplasm the arises from
the remnants of the
dental lamina and dental
organ( odontogenic
epithelium)
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Ameloblastoma Benign, locally aggressive
odontogenic tumor. Usually itslowly grows as painless swellingof the affected site.
It can occur at any age.
Localized invasion into thesurrounding bone.
80-95% in the mandible (posteriorbody, ramus region). In the maxilla
mostly in the premolar-molarregion.
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Ameloblastoma Unilocular (small lesions).
Multilocular (large discrete areas orhoneycomb appearance)
Smooth, well-defined, well-corticated margins
Adjacent teeth are often displacedand resorbed.
It causes extensive boneexpansion.
Incomplete removal can result inrecurrence.
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Ameloblastoma
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Ameloblastoma
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Adenomatoid Odontogenic Tumor
("Adenoameloblastoma")
These are uncommon ,
nonaggressive tumors of
odontoginc epthilum.
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Adenomatoid odontogenic tumor
Features
Benign. Relatively rare.
It occurs in young patients (70% of
cases in patients younger than 20years).
Most common site: anterior maxilla.
Often surrounds an entire unerupted
tooth (most commonly the canine).
Usually well defined, well corticated.Some tumors are totally radiolucent;others show evidence of internalclassification.
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Calcifying epithelial odontogenic
tumor (Pindborg tumor
These are rare
neoplasms of the
toothproducingapparuts.
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Calcifying epithelial odontogenic
tumor (Pindborg tumor Rare benign neoplasm.
It occurs more often in middle-
aged patients.
Usually in mandible.
Small lesions may be
radiolucent. In advanced
stages irregularly sizedcalcifications may be scattered
in the radiolucency.
It can cause displacement and
impaction of teeth.
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MixedOdontogenic
Tumors
OdontomasAmeloblastic
fibro-odontomaAmeloblastic
fibromaAmeloblastic
odontomaOdontomas
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Odontomas
It is a tumor that is
radiogrphically and
histologically
characterized by theproduction of mature
enamel , dentin ,
cementum and pulp
tissue . Compound # complex
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Odontoma
Features
Relatively common lesion.
It usually occurs in young patients.
Usually asymptomatic.
Failure of eruption of a permanent toothmay be the first presenting symptom.It iscommonly found occlusal to the involved
tooth.
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Odontoma
Features
Two types: complex and compoundodontoma.
Complex odontoma is composed ofhaphazardly arranged dental hard andsoft tissues.
Compound odontoma is composed of
many small "denticles" .
Well defined. The internal aspect isvery radiopaque in comparison tobone.
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Odontoma
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Ameloblastic fibroma
These are benign mixed
odontogenic tumors .
They are characterized
by neoplastic proliferationof maturing and early
functional ameloblasts as
well as the primitive
mesnchymel componentsof the dental papilla
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Ameloblastic fibroma
Benign Rare. Occurs in children and
adolescents.
Most common site: mandible posterior
region.
Often associated with an unerupted
tooth.
Well defined, well corticated. Small
lesions are monolocular. Large lesionsare multilocular.
It may cause displacement of adjacent
teeth. Large lesions cause
buccal/lingual expansion.
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Ameloblastic fibroma
A l bl ti
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Ameloblastic
fibro-odontoma
This is an extremely rare lesion. It consists
of elements of ameloblastic fibroma with
small segments of enamel and dentin.
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MesodermalOdontogenic
Tumors
Odontogenicmyxoma
(myxofibroma)
Cemento-blastoma
Odontogenicfibroma
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Odontogenic myxoma (myxofibroma)
They are benign,
intraosseous
neoplasms that arise
from the
mesenchymal portion
of the dental papilla.
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Odontogenic myxoma (myxofibroma)
Features
It represents approximately 3 - 6%of all odontogenic tumors. It ispainless and grows slowly.
It can occur at any age but mostcommonly in the second and thirddecades of life.
More often affect the mandible(molar/premolar region).
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Odontogenic myxoma (myxofibroma)
Features
Typically multilocular (internalsepta- strings of a tennis racket orhoneycomb appearance). Largelesions can have the sun ray
appearance of an osteosarcoma.
Often well-defined.
Adjacent teeth can be displacedbut rarely resorbed. It causes less
bone expansion than in otherbenign tumors.
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Odontogenic myxoma (myxofibroma)
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Cementoblastoma
This is a slow growing
mesenchymal
neoplasms composed
principally ofcementum.
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Cementoblastoma
Features
Benign neoplasm. Most commonlyin the second and third decade.
Site: usually mandibular premolar
and molar regions.
Attached to the root of the affectedtooth. Tooth displacement,resorption are common.
Pain in 50% of the cases,swelling.
When radiopaque is usuallysurrounded by a thin radiolucenthalo.
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Radiographic Features
Location:
Periphery:well defined RO
with RL hallo surrounding the
calcified mass.
Internal structure:mixed RL-
RO leseions may be
amorphous
Effect on surrounding tissues:
expansion, external root
resorption
Cementoblastoma
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Cementoblastoma
Odontogenic
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Odontogenic
fibroma
Features Rare neoplasm. More often
between the ages 10 and 40 years.
Asymptomatic or swelling and tooth
mobility
More common sites: mandible(premolar-molar region), maxilla(anterior region)
Small lesions are usually unilocular,and larger lesions multilocular.
Well-defined margins.
Adjacent teeth: often displaced,impaction, root resorption.
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Thank you