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CWIUH 25.2.2010 Bridgette Byrne Senior Lecturer in Obstetrics and Gynaecology, RCSI and CWIUH

CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

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Page 1: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

CWIUH 25.2.2010Bridgette ByrneSenior Lecturer in Obstetrics and Gynaecology,RCSI and CWIUH

Page 2: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

Near miss maternal morbidity. Lynch et al IMJ May 2008.

Severe maternal morbidity for 2004 – 2005 in the three Dublin maternity hospitals. Murphy et al EJOG March 2009.

Prediction of peripartum hysterectomy and end organ dysfunction in major obstetric haemorrhage. O’Brien et al (submitted)

Page 3: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

Definition – Acute transfusion of  ≥ 5 units of RCC

Incidence – 117 (124) / 93291 = 1.25 /1000

Hysterectomy 25

End organ dysfunction 19

Both 11

Page 4: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

Uterine atony 50%

Placenta praevia/accreta 19%

Cervical/vaginal trauma 17%

Retained placental tissue 15%

Broad ligament/uterine 10%

Page 5: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive
Page 6: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive
Page 7: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive
Page 8: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

Prenatal diagnosis of placenta accreta

Elective or emergency delivery

Oxytocics

Uterine conservation

O Negative blood

Invasive monitoring

Consultant presence

Page 9: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

Ultrasound localization of placenta 26 (100%)Upper 5Praevia 21

Ultrasound suspicion of Placenta accreta 13False positive 3/13False negative 1/8

Magnetic Resonance Imaging 6False Positive 0False Negative 3/6

Page 10: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

Elective CS (36 – 39 weeks) 13 (50%)

Emergency CS (28 – 38 weeks) 11 (42%)

Vaginal birth (34 and 39 weeks) 2 ( 8%)

Page 11: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

Oxytocin Bolus  20 (77%)

Oxytocin infusion 16 (62%)

Ergotmetrine 11 (42%)

Misoprostol 16 (62%)

Haemabate 10 (39%)

Page 12: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

EUA 3

Laparotomy 4

Uterine pack 0/2

Hydrostatic balloon 1/3

Internal iliac artery ligation 3/5

Hysterectomy (Accreta) 18/19(13)

End organ dysfunction (Accreta) 8(6)

Page 13: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive
Page 14: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

Anaesthesia General 11Spinal 8Both 7

Intraarterial line 21Central Venous Pressure Line 16Both 15None 2Missing data  2

Page 15: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

Obstetrician 88%

Anaesthetist 84%

Page 16: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

The morbidly adherent placenta is rare with an incidence of 0.3 /1000 deliveries in Dublin.Clinical suspicion very important as current modalities for prenatal diagnosis are limited.Currently almost 50% of cases are delivered as emergencies.There should be greater use of uterotonics as an adjunct to surgery.The efficacy and safety of surgical interventions and blood products need constant evaluation.Senior staff involvement critical.

Page 17: CWIUH 25.2.2010 Byrne and Gynaecology, RCSI · Senior Lecturer in Obstetrics and Gynaecology, ... (100%) Upper 5 Praevia 21 Ultrasound suspicion of Placenta accreta 13 False positive

Better prenatal identification of casesOptimal timing of elective deliveryAccess to multidisciplinary team, interventional radiology and cell salvage?Centralisation of these casesContinual high quality audit essential