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Colloque Prdserver la fertilit( Iors de t ra i tements an t icancdreux :

la c oconsewation des gametes et du tissu gonadique.

Perspectives scientifiques et enjeux thiques Ecole Normale Sup~rieure de Lyon, 18 Mars 2004

I

9 h : Introduct ion

9 h 10 - 10 h : Preserver la fertilit~ : pourquoi ?

9 h 10 : Cons6quences des traitements sur la fertilit6 de l ' homme et sa descendance.

9 h 25 : Cons6quences des traitements sur l ' infertil i t6 de la femme et sa descendance.

9 h 40 : Aspects sp6cifiques des traitements chez l 'enfant.

9 h 55 : Discussion G6n6rale

10 h 15 : PAUSE

10 h 35 - 12 h 40 : Preserver la fertilit~ : pour qui ?

10 h 35 : Caract6ristiques du sperme des hommes canc6reux : doit-on syst~matiquement congeler ?

10 h 50 : uti l isation des spermatozoides cryoconserv6s : fr6quence et r6sultats.

11 h 05 : Modalit6s de pris en charge : selon l 'urgence, et l '6tat du patient.

11 h 20 : Discussion commune.

11 h 40 : Cryoconservat ion du tissu testiculaire chez l 'enfant.

12 h 00 : Cryopr6servation du tissu ovarien chez l ' enfant et l 'adulte.

12 h 20 : Discussion commune.

14 h 40 - 14h 15 REPAS Visite des stands et des posters

14 h 15 - 15 h 15 Aspects r~glementaires et organisationnels de ractivit6 de cryoconservat ion

14 h 15 : Le point de vue du juriste.

14 h 35 : Le point de vu du praticien.

14 h 55 : Discussion commune.

15 h 15 - 16 h 45 Aspects psychologiques

15 h 15 - 15 h 25 : Le point de vue du psychologue d ' u n CECOS.

15 h 25 - 15 h 55 : Le point de vue du psychologue d ' u n service de canc6rologie

chez l ' en fan t - chez l 'adul te

15 h 55 - 16 h 15 �9 Discussion commune

1 6 h 1 5 - 1 6 h 3 5 P A U S E

16 h 35 - 17 h 30 Aspects ~thiques : Table ronde

Quelques questions : les limites d '~ge : min imales . . , maximales La mise en oeuvre de techniques qui n ' on t pas encore fait leur preuve

La responsabilit6 par rapport aux utilisations futures des gam&es ou tissu gonadique cryoconserv6s.

486 - -

�9 MANIFESTATIONS - CONGRI~S Andrologie 2003, 13, N~

Manifestations

l 0 - 11 Janvier 2004

6 ~me Col loque de M~dec ine et Psychanalyse. La fabrique des b~b~s : passions pour l'embryon Th6~tre de l 'Al l iance f r a n ~ a i s e - 105, Bd Raspail, 75006 Paris Informat ion �9 medpsycha@ paris7.jussieu.fr

5 - 7 Mars 2004 Parenthood after cancer : t o d a y ' s options and tomorrow's hopes: a multidisciplinary conference UT M. D. Anderson Cancer Center, Houston, Texas, USA Informat ion �9 Email �9 www.mdanderson .org /conferences

18 Mars 2004 F6d6ration Fran~aise des C E C O S �9 Fer t i l i t6 apr~s traitement anti-canc6reux Ecole Normale Sup6rieure de Lyon, 46, all6e d'Italie, 69007 Lyon, France Informat ion �9 Email �9 guer in@rockefel ler .univ- lyon.f r

18 - 19 - 2 0 - 21 Mars 2004

346me S6minaire de I 'A IHUS �9 San t6 sexuel le . . , du Corps au D6s i r . . .

Centre des Congrbs Pierre Baudis, Toulouse, France Informat ion �9 Email �9 la londe .d@chu- toulouse

16-20 Avril 2004

29 th Annual Meeting of the American Society of A n d r o l o g y Hyat t Regency Bal t imore, Bal t imore, Maryland, USA Informat ion �9 Email �9 www.andro logysoc ie ty .com

6 - 7 Mai 2004 Troisi~mes Journ6es Nat ionales �9 D~sir d'enfant et V I H Universi t6 Paul Sabatier, Toulouse Informat ion : Email : la londe .d@chu- toulouse . f r

31 Aofit - 4 Sep tembre 2004

12 th International Congress of Endocrinology Lisbon, Portugal Informat ion �9 Email �9 fo res t@lyon l51 . inse rm/ f r

11-14 Septembre 2004

3 rd European Congress of A n d r o l o g y (EAA) Mtinster, Ge rmany Informat ion �9 Email �9 s imoni@uni-muenster .de

9 - 11 D6cembre 2004

X X I ~me Congr~s de la Soci~t~ d ' A n d r o l o g i e de Langue Fran~aise ( S A L F ) Clermont-Ferrand, France Informat ion : Email : genevieve .gr izard @ u-clermont 1 .fr ;

j oe l .drevet @ geem.univ-bpclermont . f r

487 . . . . . .

�9 MANIFESTATIONS - CONGRI~S

PRELIMINARY PROGRAM

PARENTHOOD AFTER CANCER: TODAY'S OPTIONS AND T O M O R R O W ' S HOPES: A MULTIDISCIPLINARY CONFERENCE

UT M. D. Anderson Cancer Center, Houston, Texas, March 5-7, 2004

II I I I

F R I D A Y

Introduction: Leslie R. Schover, Conference Chair

The Survivorship Experience

Coming to terms with infertility and parenthood after cancer Panel of survivors, organized by Fertile Hope, Moderator: Lindsay Nohr

Options for Parenthood after Cancer Moderator: Lindsay Nohr The Cancer experience and motivation for biological and social parenthood Leslie Schover Adoption and third party reproduction after cancer: Practical and emotional issues Allison Rosen

Basic Mechanisms of Damage to Fertility by Cancer and Its Treatments

Impact of Cancer and its Treatments on Spermatogenesis Moderator: Anthony Thomas, Jr.

Mechanisms of toxic damage to spermatogenesis Kim Boekelheide

Disruption of spermatogenesis by the cancer disease process Ashok Agarwal

Cancer Treatment and Basic Mechanisms of Ovarian Function Moderator: Erkan Buyuk

Molecular mechanisms of follicle growth initiation and survival. Axel Themmen

Effect of anticancer agents on oocyte and follicle survival Jonathan Tilly

Basic Research on the Potential Genetic Impact of Cancer

Treatment on the Next Generation Moderator: Gordon B. Mills

The impact of cancer treatment on human germlines Andrew Wyrobek

Impact of maternal exposure to chemotherapy on embryos and offspring Dror Meirow

Impact of paternal exposure to chemotherapy on embryos and offspring Barbara Hales

Chemoprotection of Fertility: Translational Research Moderator: Rena V Sellin

Hormonal approaches to preservation and restoration of male fertility after cancer Gunapala Shetty

Efforts to use chemoprevention to protect the ovaries Naoto Ueno

SATURDAY

Fertility after Cancer Treatment Moderator: Eva Singletary

Spermatogenesis after cancer treatment" Damage and Recovery Stephen Shalet

Maintenance of ovarian function and risk of premature menopause related to cancer treatment Charles Sklar

Modifying Cancer Treatment to Preserve Fertility Moderator: Ted Trimble

488

Protection of the gonads and fetus during radiation therapy for cancer George Perkins

Fertility-sparing surgery for malignancies in women David Gershenson

Gamete and Embryo Cryopreservation before Cancer Treatment: Current Practice

Moderator: Roger Gosden

Utilization of Sperm banking, new methods of obtaining sperm, and IVF-ICSI Lar~ L Lipshultz

Embyo and ovarian tissue cryopreservation before cancer treatment and use to preserve future fertility Kutluk Oktay

LUNCH with speaker:

Legal issues related to parenthood after cancer Susan L. Crockin

Ethical Issues in Becoming a Parent after Cancer John Robertson

Gamete and Embryo Cryopreservation: Looking to the Future Moderator: Kutluk Oktay, MD

Cryopreservation and transplantation of spermatogonia for

preservation of male fertility Stefan Schlatt

Autograft vs. Xenograft? Issues for Safe Usage in Human Patients Pasquale Patrizio

When Will We Have Egg Banks? Cryopreservation and in vitro maturation of oocytes Roger Gosden

Debate: Are we ready to offer ovarian cryopreservation on a fee-for-practice basis? Pro: (10 min.) Con: (10 min.)Audience discussion: 10 min. Bioethics Debate Team: Anthony Thomas, Jr., Anne Flamm, Pasquale Patrizio,

S U N D A Y

Pregnancy-Related Issues

The Safety of Pregnancy after Cancer Treatment Moderator: Karin Gwyn

Impact of cancer treatment on uterine function Hilary Critchley

The Safety of Pregnancy after Cancer: Risk of cancer recurrence and of pregnancy complications Richard Theriault

Psychosocial Issues for women pregnant at cancer diagnosis or after cancer treatment Lari Wenzel

The health of offspring after cancer Moderator: Archie Bleyer

Offspring exposed to cancer treatment in utero Karin Gwyn

Health of offspring of survivors of pediatric cancer Les Robison

Health of offspring of survivors treated in adulthood Sophie Fossa

Special issues for inherited cancer syndrome families Moderator: Louise Strong

Reproductive risks for women with BRCA mutations Steven Narod

Preimplantation genetic diagnosis for inherited cancer syndromes: Technical progress Joe Leigh Simpson

489

Debate:

Should Prenatal Identification of inherited cancer syndromes Be Offered?

Pro: (10 min.) Con: (10 rain.) Audience discussion: 10 min.

Bioethics Debate Team: Anthony Thomas, Jr., AID, Anne Flamm, Pasquale Patrizio

Future Directions for Research and Practice

Advocacy Issues Moderator: Doug Ulman, Lance Armstrong Foundation

Fertile Hope: The role of a patient advocacy organization Lindsay Nohr

Research promoting better patient education on reproductive health after cancer Andrea Canada

Ensuring access to education and services on infertility for the underserved

Rosell Jeffries

Research Funding in Cancer and Parenthood at NCI Diana Jeffery

Research funding in cancer and parenthood at NICHD Phyllis Leppert

Conference Chair: Leslie R. Schover, PhD; Co-Chair: Marvin Meistrich, PhD

Organizing Committee: Ashok Agarwal, MD, Andrea Canada, PhD, Kutluk Oktay, MD, Lindsay Nohr

Funded by: UT M. D. Anderson Cancer Center, The National Cancer Institute, The Lance Armstrong Foundation, and Fertile Hope

490

�9 MANIFESTATIONS - CONGRI~S

Colloque Reproduction 21-23 Octobre 2004 Caen-Bagnoles de I'Orne (France)

C'est l'occasion de r6unir les chercheurs fondamentalistes, biologistes, v6t6rinaires et cliniciens impliqu6s dans le domaine de la reproduction chez le male et la femelle.

Les th6mes suivant seront d6velopp6s : Gam6togen~se, R6gulation et Physiopathologie de la Reproduction, Repro- duction et Vieillissement.

Orateurs invit6s : I. Huhtaniemi, P.Mermillod, D. Monniaux, P.Durand, B.Bilinska, V.Pezzi, M. Luconi, PTK Saunders, R.Habert, J. Bringer, M. Benahmed, N.Rives, R.Ivell, P. F6nichel, M.Canis, S.Wolczynski, Y.Reznik, JM. Kuhn, C. Ribot, SG.Hillier.

Des presentations orales s61ectionn~es sont programm6es le Samedi 23 Octobre 2004

Pour plus d'informations, inscription et pr~sentation des r ~ s u m ~ s c o n t a c t e r :

carreau @ ibfa.unicaen.fr emarie@ch-alencon.fr

Colloque Reproduction 21-23 Octobre 2004 Caen-Bagnoles de I'Orne (France)

C O N F E R E N C E S P L E I N I E R E S

I. Huhtaniemi, SG. Hill ier

S Y M P O S I U M S

G A M E T O G E N E S E

P.Mermillod, D.Monniaux, P.Durand, B. Bil inska

REGULATION d e s F O N C T I O N S d e R E P R O D U C T I O N

V.Pezzi, PTK Saunders, M.Luconi, R. Habert, J. Bringer, M. Benahmed

P H Y S I O P A T H O L O G I E de la R E P R O D U C T I O N

N.Rives, R.Ivell, P.F6nichel, M.Canis, S.Wolczynski, Y.Reznik

V I E I L L I S E M E N T et R E P R O D U C T I O N

JM.Kuhn, C.Ribot

P R E S E N T A T I O N S O R A L E S

491 ~ -