Course Sylabus for Bc

8/3/2019 Course Sylabus for Bc

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Bicol CollegeCOLLEGE OF NURSING

Daraga, Albay

Course Code: NCM 106Course Description: Care of Clients with in Inflammatory and Immunologic DisordersUnits:Time: 1:00-5:00

General Course Objectives:Successful completion of this course will promote the general student learningoutcomes listed below. The student will be able to:

1. Describe the general concepts of disease processes and factors associated with

disease causation.2. Identify the function of basic cellular structures, determining the sequelae ofselected cellular malfunctions.

3. Describe the responses of the body to injury and immunologic challenge.4. Discuss the etiology, pathogenesis, and treatment modalities of frequently

occurring diseases.

Specific Course Objectives:Upon successful completion of the course the student will be able to:

1. Describe and understand the common diseases and disorders of the human

body systems.2. Discuss the pathophysiologic changes that occurs as a result of cellular injury.3. Analyze the role of the immune system in disease processes.4. Describe the pathophysiologic changes that occur in selected disease processes

for each body system.5. Correlate the cellular and system changes that occur in selected disease

processes with common presenting clinical manifestations.6. Define the common treatment modalities and procedures associated with various

disease processes.7. List the categories of pathogenic organisms and the effects these organisms

have on the human body.8.

Describe events related to common disorders, major disease processes, andoutline the inflammatory response events.

Course Content:

A. Anatomy and Physiology of the Immune System1. Functions2. Characteristics/ Properties

a. Self versus non self recognition

b. Antibody productionc. Self regulationd. memory

3. Components of Immune System Bone marrowa. Thymus glandb. Spleenc. Lymph nodesd. Tonsils and adenoids


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4. Pathophysiology of the Development of the Cells of Immune System

B. Immunitya. Types

1. Natural/ innate2. Acquired/ artificial

b. Immune Response/ Three Means of Defense1. Phagocytic immune response2. Humoral/ antibody response

1.a antigen recognition1.b role of antibodies1.c types of antibodies

c. stages of immune response1. Recognition stage2. Proliferation stage3. Response stage

4. Effector stage

C. Assessment of Immune Functiona. Health history

i. Gender ii. Nutritioniii. Infection and immunizationiv. Allergyv. Disorders/ diseasesvi. Medications and blood transfusionsvii. Lifestyle factors

viii. Psychoneuroimmunologic factorsb. Physical examinationc. Diagnostic examination

i. Leukocyte and lymphocyte countii. Humoral immunity testiii. Cellular immunity testiv. Phagocytic cell function testv. Complement component testvi. Hypersensitivity testvii. Specific antigen-antibody testsviii. HIV infection tests

ix. ANA titer determinationx. Skin testingxi. Anti-DsDNA antibody test

D. Immune System Disordersa. Immunodeficiencies

i. Primary

Defect on Phagocytic Cells

Hyperimmunoglobulinemia E (HIE) syndrome / Job Syndrome

Chronic Granulomatous Disease (CGD

Defect on B-Lymphocytes

Bruton agammaglobulinemia/ Brutons disease/Sex linkedAgammaglobinemia

Hypogammaglobulinemia or Common Variableimmunodeficiency (CVID)

Defect on T-Lymphocytes

Di Georges syndrome or Thymic hypoplasia

Chronic Mucocutaneous Candidiasis


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Defect on B and T-Lymphocytes

Severe Combined Immunodeficiency disease(SCID)

Ataxia telangiectasia

Nezelofs Syndrome

Wiscott-Aldrich Syndrome

Defect on Complement System Angioneurotic edema

Paroxysmal nocturnal hemoglobinuria (PNH)ii. Secondary

AIDSb. Gammopathies

Multiple Myelomac. Autoimmune Diseases

Systemic Lupus Erythematosus

Rheumatoid Arthritis

Myasthenia Gravis

Multiple Sclerosis

Hashimoto Thyroiditisd. Hypersensitivity

Types of Allergens

General Etiologic Factors

Hereditary

Congenital

Contact Factors Related to the Degree of Allergic Response

Chemical Mediators of Hypersensitivity

Primary mediatorso Histamine

o Eosinophil chemotactic factor of anaphylaxis

o Platelet activating factor

o Prostaglandin

o Basophil kallikrein

Secondary mediatorso Bradykinin

o Serotonin

o Heparin

o Leukotrienes Four Types of Hypersensitivity Reactions

Type I (Anaphylactic)/Immediate Reaction

Allergic rhinitis/Hay fever

Atopic dermatitis

Dermatitis Medicamentosa/ Drug Reactions

Urticaria

Angioneurotic Edema

Hereditary Angioedema

Food Allergy

Latex Allergy

Type II (Cytotoxic) Reactions

Blood transfusion reaction

RH incompatibility

Type III (Immune Complex) Reaction

Serum Sickness

Systemic Lupus Erythematosus


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Acute Glomerulonephritis

Arthus Reaction

Type IV (Cell-Mediated)/ Delayed Reactions

Tuberculosis

Contact dermatitis

Transplant rejection

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Course Sylabus for Bc