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The Survey Committee of Japanese Association for Coronary Artery Surgery (JACAS) Coronary artery surgery results In 2017

Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

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Page 1: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

The Survey Committee of Japanese Association for Coronary Artery Surgery (JACAS)

Coronary artery surgery results

In 2017

Page 2: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Coronary artery bypass grafting (CABG), 2017

Total cases : 12,584 Isolated CABG : 8,497 (68%)(previous year:67%)

Concomitant CABG : 4,087 (32%)(previous year:33%)

Isolated CABGInitial elective : 7,144 Except initial elective :1,353

Off-pump : 4,562 Off-pump : 646On-pump : 2,582 On-pump : 707

(Off-pump rate : 64%) (Off-pump rate : 48%)(previous year : 62%) (previous year : 51%)

Page 3: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Changes of off-pump CABG rate(Initial elective CABG)

64%

0

10

20

30

40

50

60

70

80

1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017

%

year

Page 4: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Initial elective CABG :7,144(100%)

On-pump (arrest) :1,516(21.2%)On-pump (beating) :1,066(14.9%)Off-pump (total) :4,562(63.9%)Off-pump (complete) :4,431On-pump (conversion) : 131

Off-pump complete rate :97.1%

Off to on-pump conversion rate :2.9%(previous year:2.3%)

Page 5: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Mortality of isolated CABG :1.52%(previous year:1.66%)

Mortality of initial elective CABG:0.81%(previous year:1.09%)

On-pump (arrest) :0.73%On-pump (beating):1.59%Off-pump (total) :0.65%

Off-pump (complete):0.61%(previous year:0.86%)

On-pump (conversion):2.29%(previous year:5.88%)

Page 6: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Changes of mortality (Isolated and initial elective CABG)

1.52%

0.81%

0

0.5

1

1.5

2

2.5

3

3.5

4

1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017

mo

rtal

ity

(%)

year

Isolated CABG

Page 7: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Changes of mortality for procedures(Initial elective CABG)

0

1

2

3

4

5

6

7

8

2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017

mo

rtal

ity(

%)

year

Off-pump(complete)

On-pump(beating)

On-pump(arrest)

Off to on-pump(conversion)

Page 8: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Mortality according to number of diseased vessels (Initial elective CABG:7,144, mortality:0.81%)

mortality

(%)

1.0

025 50 75 100 (%)

1VD

(1.26%)

2VD

(0.44%)

3VD

(0.76%)

LMT

(0%)

LMT+2VD

(1.15%)

LMT+1VD

(0.59%)

LMT+3VD

(1.07%)

2.0

Page 9: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Mortality according to number of diseased vessels (Except initial elective CABG:1,353, mortality:5.25%)

mortality

(%)

10

5

025 50 75 100 (%)

1VD

(6.98%)

2VD

(4.03%)

3VD

(5.56%)

LMT

(5.66%)

LMT+1VD

(1.96%)

LMT+2VD

(4.79%)

LMT+3VD

(5.54%)

Page 10: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

mortality

(%)

10

5

025 50 75 100 (%)

Off-pump (total)

3.09%

On-pump

(beating)

9.63%

On-pump

(arrest)

3.32%

Mortality according to surgical procedures (Except initial elective CABG:1,353, mortality:5.25%)

Page 11: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Graft number according to procedures(Initial elective CABG)

Total

On-pump

(arrest)

On-pump

(beating)

Off to on

(conversion)

Off-pump (complete)

0 25 50 75 100%

average No.(previous year)

2.99

(3.05)

3.13

(3.17)

3.03

(3.10)

2.98

(3.25)

2.94

(2.99)

1 2 3 4≦

4≦

4≦

4≦

4≦

21

graft number

Page 12: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

4≦

0 25 50 75 100%

Off-pump

Off to on-pump (conversion) On-pump (beating)

On-pump

(arrest)

Off-pump

Off-pump

Off-pump

On-pump

(arrest)

On-pump

(arrest)

On-pump

(arrest)

62.3%

Procedure according to graft number(Initial elective CABG)

graft number

Page 13: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

On-pump (arrest) vs. off-pump (Initial elective CABG)

0 25 50 75 100%

On-pump (arrest)

On-pump (arrest)

On-pump (arrest)

Off-pump

Off-pump

Off-pump

71%

64%

92%

93%

81%

71%

bypass+

bypass −

RCA

LAD

LCX

Page 14: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Off-pump vs. off to on-pump conversion (Initial elective CABG)

0 25 50 75 100%

RCA(+) 2,908

LAD(+) 4,241

LCX(+) 3,254

RCA(−) 1,654

LAD(−) 321

LCX(−) 1,308

Off-pump

Off to on-pump conversion

2.7%

2.4%

2.7%

3.1%

9.3%

3.2%

Off-pump

Off-pump

Off-pump

Off-pump

Off-pump

Bypass No.conversion

rate

Page 15: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Age distribution according to gender (Initial elective CABG)

2000 1000 10000 0

336

796

1881

2214

635

62

91

411

665

300

49≧

60−69

50−59

70−79

≧80

(Age)Male:79.3% Female:20.7%

3000

(case)(case)

Page 16: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Changes of elderly cases(Initial elective CABG)

51.6%

12.7%

0

10

20

30

40

50

60

2000 2001 2002 2003 2004 2005 2006 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017

%

year

70 y.o. ≦

80 y.o. ≦

Page 17: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Changes of mortality according age(Initial elective CABG)

0

0.5

1

1.5

2

2.5

3

3.5

2000 2001 2002 2003 2004 2005 2006 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017

mo

rtal

ity

(%)

year

49 y.o. ≧

50-59 y.o.

60-69 y.o.

70-79 y.o.

80 y.o. ≦

Page 18: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Graft selection(Total graft number of isolated CABG:22,293)

GEA

(3.5%)

RA

(3.7%)

LITA

(35.7%)

RITA

(15.8%)

SVG

(40.9%)

Page 19: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Changes of graft selection

0

5

10

15

20

25

30

35

40

45

2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017

%

year

LITA

RITA

GEA

RA

SVG

Page 20: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

0

0.5

1

1.5

2

2.5

3

Off-pump (complete) On-pump(arrest) On-pump(beating) Off to on-pump(coversion)

%Stroke rate according to procedures(Isolated CABG)

Stroke cases:97

Stroke rate:97/8497(isolated CABG)=1.14%

0.81%

1.34%

1.86%

2.53%

p:0.4548

p:0.0058

p:0.1402

p:0.2131 p:0.4229

p:0.835

Page 21: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Results of emergency CABG after PCI complications

Emergency CABG; operation after PCI complications (coronary

occlusion and/or bleeding), within 24 hours

Cases:75

Rate:75/8497(isolated CABG);0.88%

Death cases:11

Mortality:14.67%

Results

cases death cases mortality(%)

CABG① 25 4 16.00

CABG② 26 3 11.54

CABG③ 11 1 9.09

CABG④ 8 2 25.00

Other procedures 5 1 20.00

Page 22: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Changes in results of ventricular septal perforation

Total No.:172, death:40 (mortality:23.2%)

0

10

20

30

40

50

60

mo

rtal

ity

(%)

year

Page 23: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Results of ventricular septal perforation (1)

alive

0 50 100 150

Total cases

Bypass(+)

Bypass(−)

death

40

172(mortality;23.2%)

8414

10826

132

82

(mortality;16.6%)

(mortality;24.0%)

(case)

200

70

Page 24: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Results of ventricular septal perforation (2)

0 50 100 150

Patch closure

alive

death

(mortality;23.8%)

39

12

(mortality;25.6%)

(mortality;50.0%)

(case)

Infarction exclusion

42

61

32 10

93 (mortality;22.9%)

Anterior infarction(mortality;21.2%)

Post-inferior infarction(mortality;27.1%)

47 14

Others10 (mortality;0%)

29

6

Others 8 (mortality;0%)

6

8

10

Patch closure

Infarction exclusion

10

Page 25: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Changes in results of ventricular septal perforation

according to infarction region

0

10

20

30

40

50

60

70

2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017

mo

rtal

ity

(%)

year

Anterior VSP

Post-inferior VSP

Page 26: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Changes in results of papillary muscle rupture

Total No.:68, death:13 (mortality:19.1%)

0

5

10

15

20

25

30

35

40

45

50

mo

rtal

ity

(%)

year

Page 27: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

0 20 40 60

Total cases

Bypass(+)

Bypass(−)

alive

death

68 (mortality:19.1%)

44

2414

(mortality;6.8%)

(mortality;41.6%)

(case)

1355

41

10

3

Results of papillary muscle rupture

Page 28: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Total No.:131, death:46 (mortality:35.1%)

Changes in results of LV free wall rupture

0

20

40

60

80

100

120

mo

rtal

ity

(%)

year

Page 29: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

0 50 100 150

Total cases

Bypass(+)

Bypass(−)

alive

death

131(mortality;35.1%)

(mortality;66.6%)

(mortality;20.2%)

(case)

4685

Blowout type 42 (mortality;66.6%)2814

6(mortality;66.6%)2

362412

Oozing type

Bypass(+)

Bypass(−)

891871

19 (mortality;5.2%)

1753 70 (mortality;24.3%)

18

4

1

Results of LV free wall rupture

Page 30: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Changes in results of LV free wall rupture

according to rupture type

0

10

20

30

40

50

60

70

80

2009 2010 2011 2012 2013 2014 2015 2016 2017

mo

rtal

ity

(%)

year

Blowout type

Oozing type

Page 31: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Changes in results of left ventricular aneurysm (LVA)

Total No.:170, death:9 (mortality:5.29%)

0

2

4

6

8

10

12

14

16

18

mo

rtal

ity

(%)

year

Page 32: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

0 100 200 300

Total cases

Bypass(+)

Bypass(−)

alive

death

9(mortality;5.29%)

120

161

115(mortality;4.16%)

(mortality;8.00%)

(case)

5046

170

Results of left ventriculoplasty and/or aneurysmectomy

5

4

Page 33: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

0 100 200

Total cases

death

356 (mortality;4.49%)

(case)

16340

Total

Bypass(+)

Bypass(+)

Bypass(−)

Bypass(−)

Total

262(mortality;4.19%)11251

244(mortality;4.51%)271

18(mortality;0%)18

94(mortality;5.31%)89

68(mortality;7.35%)

5

63

26(mortality;0%)26

alive

Mitral valve

plasty

Mitral valve

replacement

50 150 250

5

300

233 11

Results of MVR or MVP for ischemic MR

Page 34: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

0 25 50 75

Total cases

death

53 (mortality;7.54%)

(case)

4

Total

Bypass(+)

Bypass(+)

Bypass(−)

Bypass(−)

Total

39(mortality;7.69%)36

29(mortality;10.34%)26

10(mortality;0%)

9(mortality;11.11%)8

14(mortality;7.14%)

5(mortality;0%)

alive

Left ventriculoptasty

+Mitral valve plasty

10

13

49

5

1

3

3

Results of ischemic MR+LVA or ischemic cardiomyopathy

Left ventriculoptasty

+Mitral valve

replacement

1

Page 35: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Conclusions (1)

1. The mortality of isolated CABG was 1.52%, that of initial

elective CABG was 0.81%, indicating better excellent results

than those of previous year.

2. Of initial elective CABGs, 64% cases underwent off-pump

procedure, showing still high rate. The mortality of off-pump

was 0.61%, which was much lower than that of previous

year, indicating excellent results.

3. Off to on-pump conversion rate was 2.9%, and the mortality

of those cases was 2.29%, which was remarkable better

results than that of previous year.

4. Of all 4 and/more bypass procedures, 62.3% cases were

done by off-pump CABG.

5. CABG cases is getting older year by year, more than 70

years old patients rate was 51.6%, more than 80 was 12.7%,

showing high rate.

Page 36: Coronary artery surgery results In 2017 › data › pdf › slide_2017_e.pdfCoronary artery surgery results In 2017 Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584

Conclusions (2)

6. Arterial grafts were used in 58.8%n of all grafts, while vein

grafts were used in 40.9%. The frequency of vein graft

usage increased in recent years.

7. The complication rate of central nerve system stroke of all

isolated CABG was 1.14%. This rate of off-pump CABG

showed significantly lower than those of on-pump (beating) ,

which means that OPCAG can avoid this complication.

8. After PCI complications, emergency operation underwent in

0.88% of all isolated CABG within 24 hours. The mortality of

those cases was 14.67%, showing still high rate.

9. The results of complications for acute and old myocardial

infarction got worse than those of previous year. Especially,

the mortality of post-inferior VSP and blowout type free wall

rupture, were high rate, indicating poor prognosis.