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Copyright © 2006 by Mosby, Inc.Slide 1
Chapter 24Chapter 24 Kyphoscoliosis Kyphoscoliosis
Figure 24-1. Kyphoscoliosis. Posterior and lateral curvature of the spine Figure 24-1. Kyphoscoliosis. Posterior and lateral curvature of the spine causing lung compression. Excessive bronchial secretions (A) and atelectasis causing lung compression. Excessive bronchial secretions (A) and atelectasis
(B) are common secondary anatomic alterations of the lungs. (B) are common secondary anatomic alterations of the lungs.
A B
Copyright © 2006 by Mosby, Inc.Slide 2
Anatomic Alterations of the LungsAnatomic Alterations of the Lungs
Lung restriction and compression as a result Lung restriction and compression as a result of the thoracic deformityof the thoracic deformity
Mediastinal shiftMediastinal shift
Mucus accumulation throughout the Mucus accumulation throughout the tracheobronchial treetracheobronchial tree
AtelectasisAtelectasis
Copyright © 2006 by Mosby, Inc.Slide 3
EtiologyEtiology
Kyphoscoliosis affects about 2% of the Kyphoscoliosis affects about 2% of the people in the United Statespeople in the United States Mostly young children going through growing Mostly young children going through growing
spurtsspurts
Rarely develops in adults—unless a worsening Rarely develops in adults—unless a worsening condition from childhoodcondition from childhood
Kyphoscoliosis may also develop in adults from a Kyphoscoliosis may also develop in adults from a degenerative joint condition in the spinedegenerative joint condition in the spine
Copyright © 2006 by Mosby, Inc.Slide 4
EtiologyEtiologyAssociated with the following conditions:Associated with the following conditions: Congenital connective tissue and skeletal disordersCongenital connective tissue and skeletal disorders Hormonal imbalanceHormonal imbalance Neuromuscular disordersNeuromuscular disorders TraumaTrauma Extraspinal contracturesExtraspinal contractures Bone infections involving the vertebraeBone infections involving the vertebrae Metabolic bone disordersMetabolic bone disorders Joint diseaseJoint disease TumorsTumors
Copyright © 2006 by Mosby, Inc.Slide 5
EtiologyEtiology
Risk FactorsRisk Factors
Sex—females are 10 times more likely than Sex—females are 10 times more likely than males to develop curvature of the spinemales to develop curvature of the spine
Age—the younger the child is when Age—the younger the child is when diagnosed, the greater the chance of curve diagnosed, the greater the chance of curve progressionprogression
Angle of the curve—the greater the curvature Angle of the curve—the greater the curvature of the spine, the greater the risk that the of the spine, the greater the risk that the curve progression will worsencurve progression will worsen
Copyright © 2006 by Mosby, Inc.Slide 6
EtiologyEtiology
Risk FactorsRisk Factors
Location—in girls with lower back curvature, Location—in girls with lower back curvature, the curve is less likely to progress the curve is less likely to progress
Height—taller girls have a greater chance of Height—taller girls have a greater chance of curve progressioncurve progression
Spinal problems at birth—children with Spinal problems at birth—children with scoliosis at birth may experience a rapid scoliosis at birth may experience a rapid curve progressioncurve progression
Copyright © 2006 by Mosby, Inc.Slide 7
EtiologyEtiologyClinically, scoliosis is commonly defined according toClinically, scoliosis is commonly defined according tothe following factors:the following factors: ShapeShape
Nonstructural scoliosis—a side-to-side curveNonstructural scoliosis—a side-to-side curve Structural scoliosis—a curvature of the spine associated Structural scoliosis—a curvature of the spine associated
with vertebral rotationwith vertebral rotation LocationLocation
ThoracicThoracic LumbarLumbar ThoracolumbarThoracolumbar
DirectionDirection Left or right curvature of the spineLeft or right curvature of the spine
AngleAngle
Copyright © 2006 by Mosby, Inc.Slide 8
Cobb AngleCobb Angle
Copyright © 2006 by Mosby, Inc.Slide 9
Overview of the Cardiopulmonary Overview of the Cardiopulmonary Clinical Manifestations Associated Clinical Manifestations Associated
with KYPHOSCOLIOSISwith KYPHOSCOLIOSIS
The following clinical manifestations result from The following clinical manifestations result from the pathophysiologic mechanisms caused (or the pathophysiologic mechanisms caused (or activated) by activated) by Atelectasis Atelectasis (see Figure 9-7) and (see Figure 9-7) and Excessive Bronchial SecretionsExcessive Bronchial Secretions (see Figure (see Figure 9-11)—the major anatomic alterations of the 9-11)—the major anatomic alterations of the lungs associated with kyphoscoliosis (see lungs associated with kyphoscoliosis (see Figure 24-1). Figure 24-1).
Copyright © 2006 by Mosby, Inc.Slide 10
Figure 9-7. Atelectasis clinical scenario.Figure 9-7. Atelectasis clinical scenario.
Copyright © 2006 by Mosby, Inc.Slide 11
Figure 9-11. Excessive bronchial secretions clinical scenario. Figure 9-11. Excessive bronchial secretions clinical scenario.
Copyright © 2006 by Mosby, Inc.Slide 12
Clinical Data Obtained at the Clinical Data Obtained at the Patient’s BedsidePatient’s Bedside
Vital signsVital signs
Increased respiratory rateIncreased respiratory rate
Increased heart rate, cardiac output, Increased heart rate, cardiac output, blood pressureblood pressure
Copyright © 2006 by Mosby, Inc.Slide 13
Clinical Data Obtained at the Clinical Data Obtained at the Patient’s BedsidePatient’s Bedside
CyanosisCyanosis
Digital clubbingDigital clubbing
Peripheral edema and venous distentionPeripheral edema and venous distention Distended neck veinsDistended neck veins
Pitting edemaPitting edema
Enlarged and tender liverEnlarged and tender liver
Cough and sputum productionCough and sputum production
Copyright © 2006 by Mosby, Inc.Slide 14
Digital Clubbing
Figure 2-46. Digital clubbing.Figure 2-46. Digital clubbing.
Copyright © 2006 by Mosby, Inc.Slide 15
DistendedDistendedNeck VeinsNeck Veins
Figure 2-48. Distended neck veins (Figure 2-48. Distended neck veins (arrowsarrows).).
Copyright © 2006 by Mosby, Inc.Slide 16
Figure 2-47. Pitting edema. From Bloom A, Ireland J: Figure 2-47. Pitting edema. From Bloom A, Ireland J: Color atlas of diabetesColor atlas of diabetes, ed 2,, ed 2,London, 1992, Mosby-Wolfe.London, 1992, Mosby-Wolfe.
Copyright © 2006 by Mosby, Inc.Slide 17
Clinical Data Obtained at the Clinical Data Obtained at the Patient’s BedsidePatient’s Bedside
Chest assessment findingsChest assessment findings
Obvious thoracic deformityObvious thoracic deformity
Tracheal shiftTracheal shift
Increased tactile and vocal fremitusIncreased tactile and vocal fremitus
Dull percussion noteDull percussion note
Bronchial breath soundsBronchial breath sounds
Whispered pectoriloquyWhispered pectoriloquy
Crackles, rhonchi, and wheezingCrackles, rhonchi, and wheezing
Copyright © 2006 by Mosby, Inc.Slide 18
Figure 2-11. Figure 2-11. A short, dull, or flat percussion note is typically produced over areas A short, dull, or flat percussion note is typically produced over areas of alveolar consolidation.of alveolar consolidation.
Copyright © 2006 by Mosby, Inc.Slide 19
Figure 2-16. Figure 2-16. Auscultation of bronchial breath sounds over a consolidated lung Auscultation of bronchial breath sounds over a consolidated lung unit.unit.
Copyright © 2006 by Mosby, Inc.Slide 20
Figure 2-19. Figure 2-19. Whispered voice sounds auscultated over a normal lungWhispered voice sounds auscultated over a normal lungare usually faint and unintelligible.are usually faint and unintelligible.
Copyright © 2006 by Mosby, Inc.Slide 21
Clinical Data Obtained from Clinical Data Obtained from Laboratory Tests and Special Laboratory Tests and Special
ProceduresProcedures
Copyright © 2006 by Mosby, Inc.Slide 22
Pulmonary Function Study: Pulmonary Function Study: Expiratory Maneuver FindingsExpiratory Maneuver Findings
FVC FEVT FEF25%-75% FEF200-1200
N or N or N
PEFR MVV FEF50% FEV1%
N N or N N or
FVC FEVT FEF25%-75% FEF200-1200
N or N or N
PEFR MVV FEF50% FEV1%
N N or N N or
Copyright © 2006 by Mosby, Inc.Slide 23
Pulmonary Function Study: Pulmonary Function Study: Lung Volume and Capacity Findings Lung Volume and Capacity Findings
VT RV FRC TLC
N or
VC IC ERV RV/TLC%
N
VT RV FRC TLC
N or
VC IC ERV RV/TLC%
N
Copyright © 2006 by Mosby, Inc.Slide 24
Arterial Blood GasesArterial Blood Gases
Mild to Moderate KyphoscoliosisMild to Moderate Kyphoscoliosis
Acute alveolar hyperventilation with Acute alveolar hyperventilation with hypoxemiahypoxemia
pH PaCO2 HCO3- PaO2
(Slightly)
pH PaCO2 HCO3- PaO2
(Slightly)
Copyright © 2006 by Mosby, Inc.Slide 25
Time and Progression of Disease Time and Progression of Disease
100100
5050
3030
8080
00
PaCO2
1010
2020
4040
Alveolar HyperventilationAlveolar Hyperventilation
6060
7070
9090 Point at which PaO2 declines enough to stimulate peripheral oxygen receptors
Point at which PaO2 declines enough to stimulate peripheral oxygen receptors
PaO2
Disease OnsetDisease OnsetP
aO2
or
PaC
O2
PaO
2 o
r P
aCO
2
Figure 4-2. PaO2 and PaCO2 trends during acute alveolar hyperventilation.
Copyright © 2006 by Mosby, Inc.Slide 26
Arterial Blood GasesArterial Blood Gases
Severe KyphoscoliosisSevere Kyphoscoliosis
Chronic ventilatory failure with hypoxemiaChronic ventilatory failure with hypoxemia
pH PaCO2 HCO3- PaO2
Normal (Significantly)
pH PaCO2 HCO3- PaO2
Normal (Significantly)
Copyright © 2006 by Mosby, Inc.Slide 27
Time and Progression of DiseaseTime and Progression of Disease
100100
5050
3030
80
0
PaO2
1010
2020
4040
Alveolar HyperventilationAlveolar Hyperventilation
6060
7070
9090Point at which PaO2 declines enough to stimulate peripheral oxygen receptors
Point at which PaO2 declines enough to stimulate peripheral oxygen receptors
PaCO 2
Chronic Ventilatory Failure Chronic Ventilatory FailureDisease OnsetDisease Onset
Point at which disease becomes severe and patient begins to become fatigued
Point at which disease becomes severe and patient begins to become fatigued
Pa0
2 o
r P
aC0 2
Pa0
2 o
r P
aC0 2
Figure 4-7. PaO2 and PaCO2 trends during acute or chronic ventilatory failure.
Copyright © 2006 by Mosby, Inc.Slide 28
Acute Ventilatory Changes on Acute Ventilatory Changes on Chronic Ventilatory FailureChronic Ventilatory Failure
Acute alveolar hyperventilation on chronic Acute alveolar hyperventilation on chronic ventilatory failureventilatory failure
Acute ventilatory failure on chronic Acute ventilatory failure on chronic ventilatory failure ventilatory failure
Copyright © 2006 by Mosby, Inc.Slide 29
Oxygenation IndicesOxygenation Indices
QS/QT DO2 VO2 C(a-v)O2
Normal Normal
O2ER SvO2
QS/QT DO2 VO2 C(a-v)O2
Normal Normal
O2ER SvO2
Copyright © 2006 by Mosby, Inc.Slide 30
Hemodynamic Indices Hemodynamic Indices (Severe Kyphoscoliosis)(Severe Kyphoscoliosis)
CVP CVP RAPRAP PAPA PCWPPCWP
NormalNormal
COCO SVSV SVISVI CICI
NormalNormal NormalNormal NormalNormal Normal Normal
RVSWIRVSWI LVSWILVSWI PVRPVR SVRSVR
NormalNormal NormalNormal
Copyright © 2006 by Mosby, Inc.Slide 31
Laboratory findingsLaboratory findings
Complete blood count (CBC)Complete blood count (CBC) Elevated hemoglobin concentration and Elevated hemoglobin concentration and
hematocrit if the patient is chronically hypoxemichematocrit if the patient is chronically hypoxemic
Copyright © 2006 by Mosby, Inc.Slide 32
Radiologic FindingsRadiologic Findings
Chest radiographChest radiograph
Thoracic deformityThoracic deformity
Mediastinal shift Mediastinal shift
Increased lung opacityIncreased lung opacity
Atelectasis in areas of compressed lungsAtelectasis in areas of compressed lungs
Enlarged heart (cor pulmonale)Enlarged heart (cor pulmonale)
Copyright © 2006 by Mosby, Inc.Slide 33
Figure 24-2. Severe kyphoscoliosis in a 14-year-old male patient.Figure 24-2. Severe kyphoscoliosis in a 14-year-old male patient.
Copyright © 2006 by Mosby, Inc.Slide 34
General Management of General Management of KyphoscoliosisKyphoscoliosis
Braces (25 – 45 degree curvature)Braces (25 – 45 degree curvature) Milwaukee braceMilwaukee brace
Charleston braceCharleston brace
Boston braceBoston brace
Wilmington braceWilmington brace
Thoracolumbosacral orthosis Thoracolumbosacral orthosis
Surgery (40 – 50 degree curvature)Surgery (40 – 50 degree curvature) Posterior spinal fusion and instrumentationPosterior spinal fusion and instrumentation
Anterior spinal fusionAnterior spinal fusion
Copyright © 2006 by Mosby, Inc.Slide 35
General Management of General Management of KyphoscoliosisKyphoscoliosis
Other approachesOther approaches
Electrical stimulationElectrical stimulation
Chiropractic manipulationChiropractic manipulation
Exercise to treat scoliosisExercise to treat scoliosis
Copyright © 2006 by Mosby, Inc.Slide 36
General Management of General Management of KyphoscoliosisKyphoscoliosis
Respiratory care treatment protocolsRespiratory care treatment protocols
Oxygen therapy protocolOxygen therapy protocol
Bronchopulmonary hygiene therapy protocolBronchopulmonary hygiene therapy protocol
Hyperinflation therapy protocolHyperinflation therapy protocol
Nocturnal mechanical ventilationNocturnal mechanical ventilation
Copyright © 2006 by Mosby, Inc.Slide 37
Copyright © 2006 by Mosby, Inc.Slide 38
Copyright © 2006 by Mosby, Inc.Slide 39
Copyright © 2006 by Mosby, Inc.Slide 40
Copyright © 2006 by Mosby, Inc.Slide 41
Chest CuirassChest Cuirass
Copyright © 2006 by Mosby, Inc.Slide 42
Ankylosing SpondylitisAnkylosing Spondylitis
Rheumatologic disease affects spine and Rheumatologic disease affects spine and thoracic cagethoracic cage
Dramatically decreases thoracic cage Dramatically decreases thoracic cage compliancecompliance
Copyright © 2006 by Mosby, Inc.Slide 43
ReviewReview A posterior curvature of the spine is called?A posterior curvature of the spine is called?
KyphosisKyphosis
A lateral curvature of the spine is called?A lateral curvature of the spine is called? ScoliosisScoliosis
Kyphoscoliosis affects approximately what Kyphoscoliosis affects approximately what percentage of the U.S. population?percentage of the U.S. population? 2%2%
What is the most common form of idopathic What is the most common form of idopathic kyphoscoliosis?kyphoscoliosis? Adolescent ScoliosisAdolescent Scoliosis
Copyright © 2006 by Mosby, Inc.Slide 44
What is a nonstructural scoliosis?What is a nonstructural scoliosis? A side-to-side curve that results from a cause A side-to-side curve that results from a cause
other than the spine (poor posture, pain)other than the spine (poor posture, pain)
What is a structural scoliosis?What is a structural scoliosis? Curvature associated with vertebral rotationCurvature associated with vertebral rotation
Copyright © 2006 by Mosby, Inc.Slide 45
True / FalseTrue / False Kyphoscoliosis is classified as an obstructive Kyphoscoliosis is classified as an obstructive
disorder.disorder. FalseFalse
Girl are 10 times more likely to develop Girl are 10 times more likely to develop curvature of the spine than boys.curvature of the spine than boys. True True
Kyphoscoloiosis causes the patient’s PEFR to Kyphoscoloiosis causes the patient’s PEFR to increase.increase. FalseFalse
Copyright © 2006 by Mosby, Inc.Slide 46
Classroom DiscussionClassroom DiscussionCase Study: KyphoscoliosisCase Study: Kyphoscoliosis
Copyright © 2006 by Mosby, Inc.Slide 47
What was the patient’s P(A-a)OWhat was the patient’s P(A-a)O2?2?
Do we have enough information to calculate ODo we have enough information to calculate O22 content?content?
Copyright © 2006 by Mosby, Inc.Slide 48
Expected Effect of Acute Changes in Expected Effect of Acute Changes in PaCOPaCO22 on Arterial pH on Arterial pH
PaCO2 Change pH Change
Decrease 1 mm Hg10 mm Hg
Increase 0.01 0.10
Increase 1 mm Hg10 mm Hg
Decrease 0.006 0.06
Expected pH when measured PaCO2 < 40 mm Hg Expected pH = 7.40 + (40 – measured PaCO2)0.01
Expected pH when measured PaCO2 > 40 mm Hg Expected pH = 7.40 - (measured PaCO2 - 40)0.006
Copyright © 2006 by Mosby, Inc.Slide 49
Effect of Acute Changes in PaCO2 Effect of Acute Changes in PaCO2 on Bicarbonateon Bicarbonate
Increase in PaCOIncrease in PaCO22
Plasma HCOPlasma HCO33- - increases by 1 mEg/L for every 10 increases by 1 mEg/L for every 10
mm Hg PaCOmm Hg PaCO2 2 > 40 mm Hg> 40 mm Hg
Decrease in PaCODecrease in PaCO22
Plasma HCOPlasma HCO33- - decreases by 2 mEg/L for every 10 decreases by 2 mEg/L for every 10
mm Hg PaCOmm Hg PaCO2 2 < 40 mm Hg< 40 mm Hg