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Comparison of hypersensitivity types Type Alternative names Often mentioned disorders Mediators I Allergy (immediate) Atopy Anaphylaxis Asthma IgE II Cytotoxic, antibody- dependent Autoimmune hemolytic anemia Thrombocytopeni a Erythroblastosi s fetalis Goodpasture's syndrome Grave's disease *see type V explanation below Myasthenia Gravis *see type V explanation below IgM or IgG (Complement ) III Immune complex disease Serum sickness Arthus reaction Systemic lupus erythematosus (SLE ) IgG (Complement ) IV Delayed-type hypersensiti vity [2] (DTH), cell- mediated immune memory Contact dermatitis Mantoux test Chronic transplant rejection T-cells

Comparison of Hypersensitivity Types

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Comparison of hypersensitivity types

TypeAlternative namesOften mentioned disordersMediators

IAllergy (immediate) Atopy Anaphylaxis Asthma IgE

IICytotoxic, antibody-dependent Autoimmune hemolytic anemia Thrombocytopenia Erythroblastosis fetalis Goodpasture's syndrome Grave's disease *see type V explanation below Myasthenia Gravis *see type V explanation below IgM or IgG (Complement)

IIIImmune complex disease Serum sickness Arthus reaction Systemic lupus erythematosus (SLE) IgG (Complement)

IVDelayed-type hypersensitivity[2] (DTH), cell-mediated immune memory response, antibody-independent Contact dermatitis Mantoux test Chronic transplant rejection Multiple sclerosis [3] T-cells

VAutoimmune disease, receptor mediated (see below) Grave's disease Myasthenia Gravis IgM or IgG (Complement)