Clinical Measures

Genotype

Local Storage

BIRN Rack

SRBMCAT

HID/XNAT/LONI

DU

P

Calibration & Analysis

Tools

GRID

PortalMediator

Institution A

BIRN Rack

SRBMCAT

Institution B

… Workflow & Control: - Queries (identify subject populations, extract data, etc.) - Statistical Analysis - Download Data for: > Visualization > More Statistics > More Processing

- Interoperable Queries (literature, homology, other databases, etc.)

Human Data Protection

(De-identification Upload Pipeline, DUP)

StandardizedAcquisition

Protocol

Institution C

BIRN: Informatics Architecture

Local DB

HID/XNAT/LONI

AHM 2005Informatics - Project Goals

Databasing and Information Management

across sites Data and Tool Interoperation

• Ontology for Data Integration

Provenance Enhance Workflow Options Statistical Interface Knowledge Management

• Semantic Web Functionality

Semi-Public & Public Access to Data

ClinicalMeasures

Genotype

LocalStorage

BIRN Rack

SRBMCAT

HID/XNAT/LONI

Calibration & Analysis

Tools

GRID

PortalMediator

Institution A

BIRN Rack

SRBMCAT

Institution B

Workflow & Control: - Queries (identify subject populations, extract data, etc.) - Statistical Analysis - Download Data for: > Visualization > More Statistics > More Processing

- Interoperable Queries (literature, homology, other databases, etc.)

Human Data Protection

(De-identification Upload Pipeline, DUP)

StandardizedAcquisition

Protocol

Institution C

HID/XNAT/LONI

AHM 2005Informatics - Achievements

Since Oct04DATABASE TECHNOLOGIES Multiple HID’s in operation and with Data (~8 sites)

More Clinical Assessments in HID Improved End-to-end Uploading to SRB/HID

• (in cooperation w/ fBIRN) Multiple XNAT’s in operation with Image,

Demographic & Volumetric Data (5 instances/ 3 sites)

Provenance Structures Incorporated into XNAT & HID

Controlled Release Cycle of Tools (BIRN Release 2.0 6/14/2005)

AHM 2005Informatics - Achievements

Since Oct04KNOWLEDGE MANAGEMENT Haystack/Eclipse Semantic Environment

PUBLIC DATA Public Data (OASIS & 10/10 UCSD) to be Released

• (any day now…)

UNRELATED ACTIVITIES Red Sox win World Series…

XNAT

BuildReport

ExportControl

Browse

Drill Down

XNAT

AHM 2005Informatics - Achievements

Since Oct04

AHM 2005Informatics - Achievements

Since Oct04Haystack/Eclipse Workspace

AHM 2005Informatics - Discussion Items

Continue the expansion of BIRN-compliant Data Information Systems at Multiple Locations

Data Interoperation (Multiple instances of pool-able data across cites, within and between management platforms)

Increase Availability of Completely Public Data

Workflow

Ontology

AHM 2005Informatics - Oct 2006 Goals

To be fleshed out over next two days…

More HID and XNAT Sites & Data (UCI & JHU & +++)

Inter-site Information Sharing Between Database Systems - MAD‡ & SASHA datasets as exemplars: ‘Manual’ and ‘Automated’ Mediation Amongst Systems

XML Data‡ Interoperation Between XNAT & HID (w/ fBIRN) Continue Controlled Release Cycle of Tools (BIRN Release

2.1?) - Incorporate XNAT & HID/CALM/GAME Updates

mBIRN Public Data Portal• 10/10, OASIS (~400)‡, ADNI (~100), MIRIAD (~300), others

Workflow

Ontology

End