Clinical and histopathological correlations in rhinosinusitis

Student: Blebea CristinaConferentiar: Muhlfay GheorgheAssistant: Lostun Gabriel

Rhinosinusitis is a common and well-recognized clinical syndrome that affects a significant percentage of the patients from a Otorhinolaringology Department. Functional endoscopic sinus surgery (FESS) is now a well established strategy for the treatment of chronic rhinosinusitis(CRS) unresponsive to medical treatment. 

The objective of this study was to assess the correlation between histological and clinical diagnosis in rhinosinusitis, by evaluating the results of histopathological examination of postoperative material from FESS.

This study is a retrospective analysis based on patients who underwent FESS over a 5 years period.

The analysis covered 673 results of routine postoperative histopathological examination material from Targu-Mures County Hospital's Department of Otorhinolaringology who underwent surgical procedures between the years 2009-2013.

The histopathological examination was conducted in Hematoxylin and Eosin and PAS staining in Targu-Mures County Hospital's Morphopathology Department.

Having the ethical approval from University of Medicine and Pharmacy Tirgu-Mures, demographic data were analyzed via Chi-Square test and ROC curves using MedCalc.

A p value of less than 0.05 considered significant.

Number of patients 673

Mean age 46,9

Minimum age 5

Maximum 87

SD 16,46

2 Special aspects

Fungal rhinosinusitis

Schneider papilloma

The strong correlation between clinical inspection and pathological diagnosis of FESS

Is histological confirmation needed?

The low sensitivity of clinical diagnosis of Schneider papilloma can be reason to perform routine histopathological examination of FESS.

The close correlation between clinical inspection and histopathology outcomes indicates that in pacients with suspected CRS with or without NP histopathology has little to no clinical value.

It might be considered the improvement of diagnosing the inverted papilloma

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