CHE 4171 Biochemical Engineering

Synthetic Biology

Presentation assignment and Tutorial

Tasks at three stages for assignment of

group presentation

1. Literature search

2. Chose a topic ( a problem to solve) and submit the

pre-submission

3. Give a presentation

How to prepare?

- Read CHE3171 slides on synthetic biology (assignment folder)

- Attend two lectures on synthetic biology

- Take part in Tutorial T7 – group discussion on a paper and

brainstorm on final presentation

Brainstorm on final presentation assignment

- Which field to chose?

- Health sector (therapeutics and diagnostics)

- Biotransformation

- Bioremediation (environmental control)

- What problems to solve?

- What methods to use?

- Group discussion on four selected papers

– Groups A and B• “Biosynthesis of isoprene in Escherichia coli via methylerythritol phosphate

(MEP) pathway”

– Groups C and D • “Engineering Escherichia coli to see light”

– Groups E and F• “Escherichia coli W as a New Platform Strain for valine production”

– Group G• “Metabolic engineering of Escherichia coli for direct production of 1,4-

butanediol”

• Brain storm on group presentation

Tutorial 7 (next week)

1. What is the key problem the paper has solved?

2. Why the studied problem is important?

3. What is the key method (methods) in the paper?

4. Give your own opinion about this paper.

5. If it were you to do the research, how would you do differently?

Group discussion on the following questions (15 min)

Tutorial 7 (next week)

A short presentation (4-5 slides) at the end of discussion

(10 min)