266 Cell Biology International Reports, Vol. 15, No. 3, 1991 2. Cell to Cell Interaction. International Symposium, Basel, Sept 1990 I Editors H.M.Burger, B.Sordat and R.M.Zinkernagel. Karger. ~~252. UK 86.10/W 158.50. Cell to cell interaction can cover almost every area of cell biology that one likes to consider. Here the organisers have concentrated, and extremely successfully, on three areas of intense current activity. These are oncology, neurobiology and, it almost goes without saying, immunology. These very broad topics have so much in common that one can create a matrix approach and ask, for example, what role do adhesion molecules have in each? what are the actions of the different growth factors already known, are they synergistic or antagonistic or totally independent? In view of this particular symposium one can add, how does my knowledge help me to understand and hopefully arrest disease processes. The first section on neurobiology includes contributions which give us the very latest information on TGF-B and retinoids on the one hand and on the other hand a chapter on lymphocyte-associated surface molecules which covers much of the knowledge on leukocytes as well. Cell adhesion and cell trafficking also play an important role in tissue repair and regeneration as related to the CNS in this context. Cell phenotyping is not neglected. Another area of widespread interest is the active role of the extracellular matrix which links the first two sections. Again TGF-B plays a major role here affecting both general cellular function and cell-cell interaction as in tumour development. Selected presentations on B-cells, mast cells, and features of the immune system such as cell cooperation are all dealt with in some detail. This is a well presented volume which deserves serious study particularly by medical researchers. The plant scientists are not neglected and with the interest generally in the immune system of higher plants will find much to interest them. The editors are to be congratulated on the quality of the contributions and the speed of production, within three months! GRTB.

Cell to cell interaction. International Symposium, Basel, Sept 1990 Editors M.M. Burger, B. Sordat and R.M. Zinkernagel. Karger. pp 252. UK 86.10/US 158.50

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Page 1: Cell to cell interaction. International Symposium, Basel, Sept 1990 Editors M.M. Burger, B. Sordat and R.M. Zinkernagel. Karger. pp 252. UK 86.10/US 158.50

266 Cell Biology International Reports, Vol. 15, No. 3, 1991

2. Cell to Cell Interaction. International Symposium, Basel, Sept 1990 I Editors H.M.Burger, B.Sordat and R.M.Zinkernagel. Karger. ~~252. UK 86.10/W 158.50.

Cell to cell interaction can cover almost every area of cell biology that one likes to consider. Here the organisers have concentrated, and extremely successfully, on three areas of intense current activity. These are oncology, neurobiology and, it almost goes without saying, immunology.

These very broad topics have so much in common that one can create a matrix approach and ask, for example, what role do adhesion molecules have in each? what are the actions of the different growth factors already known, are they synergistic or antagonistic or totally independent? In view of this particular symposium one can add, how does my knowledge help me to understand and hopefully arrest disease processes.

The first section on neurobiology includes contributions which give us the very latest information on TGF-B and retinoids on the one hand and on the other hand a chapter on lymphocyte-associated surface molecules which covers much of the knowledge on leukocytes as well. Cell adhesion and cell trafficking also play an important role in tissue repair and regeneration as related to the CNS in this context. Cell phenotyping is not neglected.

Another area of widespread interest is the active role of the extracellular matrix which links the first two sections. Again TGF-B plays a major role here affecting both general cellular function and cell-cell interaction as in tumour development. Selected presentations on B-cells, mast cells, and features of the immune system such as cell cooperation are all dealt with in some detail.

This is a well presented volume which deserves serious study particularly by medical researchers. The plant scientists are not neglected and with the interest generally in the immune system of higher plants will find much to interest them. The editors are to be congratulated on the quality of the contributions and the speed of production, within three months!

GRTB.