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Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

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Page 1: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers
Page 2: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Cell Membrane Structure

Lipid bi-layerProteins imbedded as channels for transfers

Page 3: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Selective PermeabilitySelective Permeability

Property of cell membrane

Allows some substances in/out

Cells need nutrients/oxygen in

Cells need carbon dioxide/wastes out

Page 4: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Particles of matter in constant motion.

Solid particles move less than liquids & gases.

Particles move from crowded areas to less crowded areas until equilibrium is reached (evenly dispersed)

Background Information

Page 5: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

- net movement of molecules from areas of HIGH concentration to LOW concentration

Diffusion Definition

Page 6: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Diffusion Example

Diffusion of perfume in a classroom!

The Diffusion Applet

Page 7: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Facilitated Diffusion

Carrier protein: molecules in cell membrane that “help” substances move in/out of cell

Specific protein for each moleculeType of Passive TransportUsed for:

– Molecules too large for fluid membrane– Molecules not soluble in lipid bilayer

animation

Page 8: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Osmosis

Osmosis:Osmosis: movement of water across cell membrane

• from high concentration to area of lower concentration

-AKA the diffusion of water.

Page 9: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Osmosis: Diffusion of Water

Page 10: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

“Solution” for your Transport

Solution is:– A solute dissolved in a solvent

Solvent is:– Generally is water in living systems

Solute is:– Glucose, oxygen, salt etc; that which is dissolved in

the solvent

WHAT IS THE SOLVENT AND WHAT IS THE SOLUTE WHEN YOU MAKE JELLO???

Page 11: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

What is concentration?

Mass of solute in a given volume. (example: g/L)– 30 grams of solute in 2 liters of water: 30 g/ 2 L OR 15

g/L

Which of the three has the greatest concentration?– 30 grams of sugar in 5 L of water– 20 grams of sugar in 40 L of water – 50 grams of sugar in 25 L of water?

Page 12: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Concentration Gradient

The difference in the concentration of molecules across a space.

Molecules are said to move down a concentration gradient.

Page 13: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

What happened here?

Draw a sketch of the solutions:

Page 14: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Hyper vs. Hypo

Hypertonic – The solution with a higher concentration of solute in it. Hypotonic – The solution with a lower concentration of solute in it.

Isotonic – solutions which have equal concentrations of solute.

Page 15: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Direction of OsmosisIsotonic: Cell and environment have equal concentration of solute

Hypotonic: Cell has a lower concentration of solute than the environment

Hypertonic: Environment has higher concentration of solute than the cell

20% salt

80% salt

Page 16: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Plasmolysis

O Shrinkage cytoplasm inside the cell membrane

O Due to the loss of water from a plant cell

O Causes plants to wilt - Loss of inside cell pressure: Turgor Pressure

Page 17: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Dealing With Osmosis

Contractile Vacuoles (protozoa)– Pumps excess water out

Plasmolysis (plant cells)– Water loss; turgor pressure drops

Cytolysis (animal cells)– High turgor pressure; cell explodes

Page 18: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers
Page 19: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Passive TransportPassive Transport

movement down concentration gradient

cells do not use energy;- particles move by kinetic energy

includes: diffusion, osmosis, facilitated diffusion

Page 20: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Active TransportActive Transport

- Movement from LOW concentration to HIGH concentration (UP concentration gradient!)

- Cells use energy (ATP)

Example: plant roots pull in minerals from soil

Page 21: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Active v.s. Passive Transport

Page 22: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

EndocytosisEndocytosis

- Cell membrane:o surrounds a substanceo pinches offo forms a vesicleo brings substance IN

-Includes:o Phagocytosis o Pinocytosis

Page 23: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Phagocytosis 1 2 3

Phagocytosis

Page 24: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

ExocytosisExocytosis

Vesicle contents are released at the cell membrane

Page 25: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers

Application of Diffusion / Osmosis

Dialysis

o Kidney job: filter wastes from your blood

o Damaged kidney hook patient up to dialysis

- Blood is run from body to dialysis machine

- Machine filters out wastes by diffusion.

- Cleansed blood is returned to the body

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Kidneys

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Fish Gill FunctionThis is a close-up of a thin channel in the fish's gills. Water flows through it and is surrounded by blood vessels, that flow in opposite direction. The oxygen leaves the

water, and goes into the blood. From there, it is carried all around the body of the fish!

Page 28: Cell Membrane Structure Lipid bi-layer Proteins imbedded as channels for transfers