By: Nancy Lorenzini Chelation and Hyperbaric Oxygen Therapies - Treatment for Autism?

By:Nancy Lorenzini

Chelation and Hyperbaric Oxygen Therapies -Chelation and Hyperbaric Oxygen Therapies -

Treatment for Autism?Treatment for Autism?

Search Terms:Chelation and autismChelation therapyThimerosal and autismMercury and autismAlternative Therapies and autismAutistic Spectrum Disorders (ASD)Autism TreatmentsVaccines and autismDevelopmental Disabilities

Where Did I Go For InformationWhere Did I Go For InformationSearch Engines: Psych info, Proquest Research Library, Health Reference Center,

Health Wellness Resource Center, PsychArticles, Science Digest, and Google

Search Terms:Hyperbaric Oxygen Therapy ad

autismHBOTHyperbaric Oxygen TherapyHyperbaric Chamber, Hyperbaric Oxygen TreatmentAutistic Spectrum Disorders and

Hyperbaric Oxygen Therapy, Alternative Therapies and autism

Other: Dan Doctors, CDC, FDA, American Cancer Society, American Heart Association

http://www.freewebs.com/eclectives/messtoons.htm

(key-lay-shun)

What is Chelation Therapy?

Process where harmful metal toxins are extracted from the body

Chelating agents injected into body (2 types of amino acids)

These agents bind to metals ions and secrete them out of the body

http://research-chelation-therapy.com/about-autism-chelation-therapy/a-brief-history-of-chelation

Chelation (key-LAY-shun)Chelation (key-LAY-shun)

History•First used in World War I as an antidote for arsenic based poisonous gas•After World War II it was used to treat Navy personnel•In the 1960’s the formula was modified and was the leading treatment for lead, arsenic, and mercury poisoning.•Many different chelating compounds have been discovered


What is Chelation Therapy Approved For?

American Academy of Child and Adolescent Psychiatry adopted guidelines for screening of lead poisoning and treatment

A individual shows (serious) elevated blood levels of lead in body through blood tests

Use Chelation therapy of Calcium EDTA

http://www.aacap.org/cs/root/policy_statements/screening_children_for_lead_guidelines_for_children_and_adolescent_psychiatrists

Chelation Therapy “experts” claim this treatment works for everything from Clogged Arteries to sexual dysfunction

Freeman, S. K. (2007). The Complete Guide to Autism Treatment. Lynden, WA: SKF Books USA, Inc.

Removes undesirable metals from the body Reverses the process of atherosclerosis Improves cerebrovascular arterial occlusion Improves memory, concentration, and vision Reversal of gangrene Restoration of memory Prevents and reverses problems of degenerative diseases Arthritis, scleroderma, and lupus Radiation toxicity Snake venom poisoning Digitalis intoxication Cardiac arthymia


Relationship to Autism

The theory is that heavy metals have accumulated in the child’s system and detoxification of these heavy metals (mercury) will improve symptoms.

One source of mercury is thought to be timerosol in vaccines

Mehl-Madrona, L., (2010). Detoxification for Heavy Metals as a Treatment for Autism. Retrieved October 10, 2010 from http://www.healing-arts.org/children/detoxification.htm

Therefore, if the mercury is removed from the body, the symptoms will improve

Relationship to Autism Chelation Approved for use with individuals

that tested through blood tests to have lead

arsenic, or mercury poisoning .

Mercury

Mercury

Vaccines

Autism

HeavyMetal =

Vaccines

Autism

Chelation

Autism Research Institute . (2005). Treatment Options for Mercury/Metal Toxicity in Autism and Related Developmental Disabilities: Consensus Position Paper . Retrieved on 17 Oct 2010. http://www.autism.com/pdf/providers/heavymetals.pdf

Blood Testing – tests present level in blood

Hair – measures excretion

Unprovoked urine –measures excretion (recent exposure)

Antibody Testing – glutathione (controls excretion)

Provocation Testing – measuring excretion

What do the “Expert” Say?

“Experts” - Testing

Detoxification Testing – This proves that metals were in the system and that the detoxification agent removed the metals.


Limitations“One major limitation of these tests is that the reference range for the urine or stool generally involves a comparison to people who are NOT taking a detoxification agent, so that even a normal person would tend to have a high result. Thus, an experienced clinician needs to interpret the results carefully.”

“One complexity of provocation tests is that the detoxification agent may preferentially bind to one metal first, so excretion of that metal may hide the presence of other metals. Mercury can be tightly bound to body tissue, and it may not be removed until significant amounts of other toxic metals have been removed.”

“Another limitation is that low doses of the detoxification agents may fail to increase excretion significantly. It is not fully understood, but it appears that the first part of the dose may be neutralized by the body, so higher doses may be needed for provocation testing vs. long-term treatment.”

http://www.evenbetternow.com/ (evenbettenow.com LLC)

http://www.detoxamin.com/ (World Health Products)

http://www.maxamlabs.com/ (Maxam Nutraceutics)

What Do “Experts” Say?

The use of these products are so simple that they can be done at home by untrained personnel!

What Research Support Does Chelation Have?

CaEDTA Suppositories to Treat Elevated Blood Lead Levels in Children by Ted Rozema, MD

World Health Products sites as support a study by Ted Rozema, MD – lead Poisoning CaEDTA Suppositories to Treat Elevated Blood Lead Levels in Children

Maxamlabs.com uses testimonials - http://www.maxamlabs.com/shopcontent.asp?type=Testimonial-Autism

Almost Instant Gratification – p17 http://www.maxamlabs.com/shopcontent.asp?type=Testimonial-Autism-Behavior

http://www.maxamlabs.com/shopcontent.asp?type=Testimonial-Autism

http://www.maxamlabs.com/shopcontent.asp?type=Testimonial-Autism-Behavior

http://www.healing-arts.org/children/detoxification.htm (Mehl-Madrona, M.D., Ph.D)

What Research Support Does Chelation Have?

http://www.youtube.com/watch?v=hnsZ1zDb14E&feature=related

Is Chelation Safe?According to the American Heart Association (2010), there are serious dangers associated with Chelation therapy. EDTA can cause the following:

kidney failure bone marrow depressionshock

convulsions

low blood pressure (hypotension)

cardiac arrhythmias

respiratory arrest

death

American Heart Association. (2010). Questions and Answers about Chelation Therapy. http://www.americanheart.org/presenter.jhtml?identifier=3000843 Retrieved 19 September 2010

Pediatrics for Parents. Jan 2009 v25 i1 p5 (1).

The study was cancelled before it starteda study of rats with elevated lead levels that received Chelation therapy displayed improved learning, attention and arousalthey also had lasting cognitive impairment. The cognitive impairment was even present in rats with normal lead levels that received the Chelation therapy.

The National Institutes of Health (NIH) through the National Center for Complementary and Alternative Medicine

funded a five-year study of Chelation therapy 120 children with autism four to ten years old. Half were to be given Chelation pills and the other half placebos.

Oops!

October Newswire

On October 14, 2010, the FDA warned eight On October 14, 2010, the FDA warned eight companies that are marketing Chelation companies that are marketing Chelation products used for unapproved treatments products used for unapproved treatments and making false claims about the products and making false claims about the products is a violation federal law is a violation federal law

Chelation products, even when used under Chelation products, even when used under medical supervision, can cause serious medical supervision, can cause serious harm, including dehydration, kidney harm, including dehydration, kidney failure, and death.failure, and death.

US Department of Health and Human Services. (2010). FDA issues warnings to marketers of unapproved ‘Chelation’ products. Retrieved October 22, 2010 from http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm229320.htm

Company’s

http://www.fda.gov/Drugs/ResourcesForYou/Consumers/BuyingUsingMedicineSafely/MedicationHealthFraud/ucm229313.htm

World Health Products, LLC Hormonal Health, LLC and World Health Products, LLC Evenbetternow, LLC Maxam Nutraceutics/Maxam Laboratories Cardio Renew, Inc. Artery Health Institute, LLC Longevity Plus Dr. Rhonda Henry

Worthwhile Therapy?According to Schechtman (2007), “children who received heavy metal Chelation failed to demonstrate improve neurodevelopment functions on follow-up.”

Schechtman, M. A., (2007). Scientific Unsupported Therapies in the treatment of Young Children with Autism Spectrum Disorders. Psychiatric Annals 37 (9). 639-645

“Currently, there is no scientific data published in peer-reviewed journals to suggest that chelation Therapy is an effective treatment for individuals with autism” (Freeman, 183).


“The National Council Against Health Fraud believes that Chelation therapy is unethical and should be banned and that Chelation therapy of autistic children should be considered child abuse” (Freeman, 188).

The use of chelation therapy to treat autistic children is completely bogus (quackwatch.com)

http://www.quackwatch.com/03HealthPromotion/immu/thimerosal.html

What is Hyperbaric Oxygen Therapy (HBOT)?

Hyperbaric oxygen therapy (HBOT) is done in a sealed chamber pressurized at 1 ½ to 3 times normal atmospheric pressure where the patient is breathing pure oxygen.

American Cancer Society. (2010). Hyperbaric Oxygen therapy. Retrieved October 22, 2010 from http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/hyperbaric-oxygen-therapy

History of Hyperbaric Oxygen Therapy?

Hyperbaric Oxygen Therapy (HBOT) has been used in medicine since the 1600’s.

Used safely since 1930’s for decompression sickness (the bends and caisson disease)

Used clinically since 1800’s

Developed and tested after World War I

About.com (2010). The History of Hyperbaric Chambers and Hyperbaric Oxygen Therapy . Retrieved October 10, 2010 from http://inventors.about.com/library/inventors/blhyperbaric.htm

The Hyperbaric Oxygen Committee was developed by the UHMS in 1976 to oversee the ethical practice of hyperbaric medicine

History of Hyperbaric Oxygen Therapy

(Continued)In 1967, the Undersea and Hyperbaric Medical Society (UHMS) was founded.


The bends is the common name given to decompression sickness or caisson disease. The bends occur when the pressure surrounding a person’s body drops quickly and air bubbles form in the blood stream. Most commonly, when a diver resurfaces too quickly. However, it also may occur when an unpressurized aircraft flies into lower pressure or when a miner resurfaces from a mine that has been pressurized to keep water out.

Approved uses for HBOT

Claims (Approved)Claims (Approved) Air or Gas Embolism Bone Grafts Carbon Monoxide Poisoning and Smoke Inhalation Carbon Monoxide Poisoning Complicated by Cyanide Poisoning Clostridial Myonecrosis (Gas Gangrene) Crush Injury, Compartment Syndrome Decompression Sickness (the "Bends") Enhancement of Healing in Selected Problem Wounds Exceptional Blood Loss (Anemia) Necrotizing Soft Tissue Infections Osteomyelitis (Refractory) Radiation Tissue Damage (Osteoradionecrosis) Skin Grafts and Flaps (Compromised) Thermal Burns

FDA. (2001). Warning letter from US health and Human Services. Retrieved October 20, 2010 fromhttp://www.fda.gov/downloads/ICECI/EnforcementActions/WarningLetters/2001/UCM069421.pdf

Claims (Not Approved)Acute Acoustic TraumaAcute and Chronic AnemiaAcute and Chronic Arterial InsufficiencyAIDSALS "lou Gehrig's Disease"Alzheimer's DiseaseAutistic disordersCandidas and Fungal InfectionsCerebral edemaCerebral Palsy, Epilepsy due to HypoxiaChemical Poisoning (e.g. Pesticide)Chronic Fatigue SyndromeClosed head injuryColitisCrohn’s Disease

Compartmental SyndromeDiabetesFibromyalgiaFlesh Eating BacteriaFracture RepairGastric and Duodenal UlcersGuillain-Barre SyndromeHeadaches, ClusterHeart attack, Myocardial Ischemia & Aid to Cardiac Surgery and RehabilitationHypoxic Birth DisordersInflammatory ArthritisLupusLyme DiseaseMacular DegenerationMigraineMultiple SclerosisMusculoskeletal InjuriesMycoplasma

Hyperbaric O2ptions (2010). Discover Hyperbarics. Retrieved on October 24, 2010 from http://www.discoverhyperbaric.com/HBOT-approved-experimental-off-label-indications.html

Musculoskeletal InjuriesMycoplasmaNear drowningNear hangingNeurovascular compressionOsteoporosisParkinson’s diseasePeripheral nerve injury and neuropathies, demyelinationPeripheral Vascular DisordersPost surgical instabilityRehabilitative CareRetintis PigmentosaRSDRheumatoid ArthritisSacroiliac SyndromeScelodremaSilicone Induced DisordersSpinal Cord injurySpider biteHyperbaric O2ptions (2010). Discover Hyperbarics. Retrieved on October 24, 2010 from http://www.discoverhyperbaric.com/HBOT-approved-experimental-off-label-indications.html

Silicone Induced DisordersSpinal Cord injurySpider bite StrokeSudden deafness Surgery Healing, Pre and Post, Reconstruction and Cosmetic SurgeryPost surgical soft tissue infectionsTOSVegetative comaWound Healing, Recurrent Ulcers and Infections


http://www.youtube.com/watch?v=cc8yFhFVehE

Hope Fine, South Florida Center for H.O.P.E.

Claims

Because the South Florida Center for H.O.P.E., is a free-standing facility, we have the opportunity to treat a spectrum of diagnosis including, but not limited to Autism, Cerebral Palsy, Stroke, Traumatic Brain Injury, PTSD, Multiple Sclerosis, Lyme Disease, Spinal Cord Injury, Near Drowning, Fibromyalgia, Migraines, Sports Injuries, Pre and Post Cosmetic Surgery and Cancer, as well as Non-healing Wounds, Radiation Injury, and Carbon Monoxide poisoning.

South Florida Center for H.O.P.E. (2010). Retrieved September 29, 2010 from http://sfcenterforhope.com/

Pauline Anderson (2009). Hyperbaric Therapy May Improve Autism Symptoms. Medscape Medical News

SupportDr. Rossignol et al. conducted a few studies on children diagnosed with autism using hyperbaric oxygen therapy.

Conclusions are promising.

Important Limitations: 8 of the 10 authors including Dr. Rossignol make money

from hyperbaric oxygen therapy treatments.Dr. Rossignol and two other investigators received research

funding from Hyberbarics Association on a earlier study

Much of the study was evaluated on parental rating scales and this leaves room for bias.

The control group rated better than the treatment group in the areas of social withdrawal and hyperactivity

http://www.youtube.com/watch?v=Xs3KuaoUe8w&feature=related http://www.youtube.com/watch?v=geBUrrLa3XI&feature=related

Support

http://www.drneubrander.com/dev/index.html

http://www.californiahyperbarics.com/page_coming_soom.html

Is HBOT Safe?Otic Barotrauma (pain in the ears or sinuses)

Serous Otitis

Oxygen Toxicity

Visual Changes

Maturing or Ripening Cataracts

Cerebral Air Embolism and Pneumothorax

Risk of Fire.

http://www.aurorahealthcare.org/services/hyperbaric/faq.asp

Chronic sinusitis Congenital spherocytosis Emphysema with CO2 retention History of optic neuritis History of reconstructive ear surgery History of spontaneous pneumothorax History of thorax surgery Pulmonary lesions in routine X-ray or CT scan Seizure disorders Sickle cell anemia Uncontrolled high fever Upper respiratory infections Viral infections

Contraindications to Hyperbaric Oxygen Therapy

http://www.aurorahealthcare.org/services/hyperbaric/faq.asp

"NO"Nylon Bras Contact Lenses Dentures Girdles Hair Accessories Hats or Caps Hearing Aides Jewelry (Watches, Rings, Bracelets, Etc) False Eyelashes Nail Polish (Must be dry at least 24 hours) Nylons (Hose or Pantyhose) Oral Retainers Support Braces (Unless approved by attending technician) Synthertics (I.E Rayon, Hylon, Etc) Wigs or Hair Pieces

Absolutely "NO" Blankets Books or Newspapers CD Players Cell Phones Crayons Lighters Matches Paper Products of Any Kind Pens Pencils Pocket Warmers redios Toys Electronic Games Laptop Computer

You Must Not Have Used: Deodorant Hair Gel or Mousse Hair Spray Lotions Make Up Ointments Perfume Petroleum Based Products/Vaseline Products Liniments Aftershave Products Salves

www.sfcenterforhope.com

Is HBOT Safe?

http://www.hyperbaric4autism.com/

Cost?

http://www.dive-hyperbarics.com/

http://www.hyperbaricsrx.com/hyperbaric-chamber-products.html

Worthwhile Therapy?

http://www.asatonline.org/helpdesk/research/hyperbaric.htm


American Cancer Society. (2010). Hyperbaric Oxygen therapy. Retrieved October 22, 2010 from http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/hyperbaric-oxygen-therapy

FDA. (2001). Warning letter from US health and Human Services. Retrieved October 20, 2010 fromhttp://www.fda.gov/downloads/ICECI/EnforcementActions/WarningLetters/2001/UCM069421.pdf


American Heart Association. (2010). Questions and Answers about Chelation Therapy. http://www.americanheart.org/presenter.jhtml?identifier=3000843 Retrieved 19 September 2010


Baker, Jeffrey P.. American Journal of Public Health, Feb2008, Vol. 98 Issue 2, p244-253, 10p; (AN 30103018)

CDC (1991): Strategic Plan for the Elimination of Childhood Lead Poisioning. Centers for Disease Control, Department of Health and Human Services, Atlanta, GA.


Mayo Clinic. (2010). Autism treatment. Can Chelation therapy help? Retrieved October 16, 2010 from http://www.mayoclinic.com/health/autism-treatment/AN01488

Pardo CA, Eberhart CG. The neurobiology of autism. Brain Pathology 2007: 17(4): 434-47.


http://www.aacap.org/cs/root/policy_statements/screening_children_for_lead_guidelines_for_children_and_adolescent_psychiatrists

http://www.youtube.com/watch?v=cc8yFhFVehEhttp://www.youtube.com/watch?v=cc8yFhFVehE

Rossignol DA, et al. Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trial. BMC Pediatr.2009 Mar 13;9(1):21.

Quackwatch, http://www.quackwatch.com/03HealthPromotion/immu/thimerosal.html

Rossignol, D et al. “The effects of hyperbaric oxygen therapy on oxidative stress, inflammation, and symptoms in children with autism: an open-label pilot study.” BMC Pediatrics 2007, 7:36.

Rossignol, D., “Hyperbaric oxygen therapy may improve symptoms in autistic children.” Med Hypotheses. 2006:67 (2) 216-28.

http://www.hyperbaric4autism.com/

http://www.dive-hyperbarics.com/

http://www.hyperbaricsrx.com/hyperbaric-chamber-products.html

http://www.drneubrander.com/dev/index.html

http://www.youtube.com/watch?v=cc8yFhFVehE

http://www.youtube.com/watch?v=hnsZ1zDb14E&feature=related

http://www.evenbetternow.com/

http://www.detoxamin.com/

http://www.maxamlabs.com/

Any Questions?Any Questions?

Thank you!!

Documents

By: Nancy Lorenzini Chelation and Hyperbaric Oxygen Therapies - Treatment for Autism?