Borrelia Practice Questions

7/26/2019 Borrelia Practice Questions

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1. What diseases do the bacteria of the genus Borrelia cause?

2. What is the structure of Borrelia?

3. Causative agent of leptospirosis

4. Causative agent of syphilis

5. Type of otility that is enabled by the periplasic flagella of spirochetes such as Borrelia

!. Techni"ues that could be used to visuali#e $pirochetes

%. &o' is the Borrelia genoe organi#ed

(. What co)factor does Borrelia utili#e for en#yes that re"uire a cofactor

*. &o' does Borrelia a+e energy for its survival?

1,. What does Borrelia e-hibit au-otrophy for?

11. What is the function of the esT en#ye

12. Copare and contrast noral linear /0 and the linear /0 of Borrelia

13. -plain the process of Teloere resolution. What does it ean? The olecules involved? nd

'hy is it done?


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14. The vector for ye disease

15. Causative agent of ye disease

1!. -plain the difference bet'een a nyph and adult deer tic+ and ho' the difference affects

developent of ye disease.

1%. 0ae of the rash caused by the bite of a tic+ infected 'ith Borrelia Burgdorferi


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1(. What are the stages of ye disease and the disease syptos associated 'ith each stage

1*. $+etch the Borrelia burgdorferi life cycle

2,. Ter for a host that does not transit the disease to other organiss


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21. /oes Borrelia have $?

22. ist the ain outer surface proteins of Borrelia burgdorferi that contributes to pathogenicity

23. -plain the role of sp proteins in survival of Borrelia burgdorferi in tic+s. 6a+e sure to ention

the changes in e-pression of sp proteins as the tic+ ta+es blood eals.


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24. 7unction of spC

25. -plain the function of the c)di)86 second essenger in Borrelia

2!. What is rp1 and 'hat role does it play in Borrelia survival in tic+


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2%. What are C$s and 'hen are they e-pressed. lso list all the C$s and their function.

2(. What is the function of 9ls

2*. -plain the process of antigenic variation of 9ls


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3,. Causative agent of relapsing fever

31. What are the syptos of relapsing fever?

32. Tic+s that transit the pathogen responsible for relapsing fever.

33. -plain the process of antigenic variation of 9sp:9lp proteins in B. hersii


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34. Copare and contrast antigenic variation in Borrelia burgdorferi and in Borrelia hersii


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Borrelia Practice Questions