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1. Dr K’s office hours: Today 2:30 -‐ 3:30 PM (Mee0ng room: 3502 Pacific Hall) Fridays 11:00 AM -‐ noon (Mee0ng room: 3501 Pacific Hall)
2. Dr K’s problem-‐solving session: Wed 5-‐6 in 3500 Pacific Hall Thurs 5-‐6 in 3500 Pacific Hall.
3. Midterm exam will cover through Autonomic Nervous System (not Hormones)
4. Dr. K’s e-‐mail: [email protected] (put BIPN 100 in the subject line)
5. TA secKons, office hours:
BIPN100 Human Physiology 1 Bill Kristan, Ph.D.
Web site: hRp://classes.biology.ucsd.edu/bipn100B.FA15/
. Sec0on IA Office Hour .
Fri 11:00-‐11:50am SEQUO 148……Winjet Chou………….… Wed 3-‐3:50 pm HSS 1145B
Fri 12:00-‐12:50pm SEQUO 147…. Saatchi Patell……………. Wed 1-‐1:40 pm Muir Woods
Fri 1:00-‐1:50pm WLH 2115 ….. JusKne Liang…………… Tues 10-‐10:50 am Hi Thai
Fri 2:00-‐2:50pm WLH 2206 …… Hao Shi…………………… Fri 3-‐3:50 pm HSS 1128A
Mon 9:00-‐9:50am WLH 2115……. Tim Macaulay………….. Tues 12:30-‐1:20 pm Mandeville Coffee Cart
Mon 4:00-‐4:50pm WLH 2208……. Mallorie Nguyen……… Thurs 2-‐2:50 pm Goody's Market
Mon 5:00-‐5:50pm WLH 2208…… Donel Purcella…………. Mon 3:30-‐4:20 pm Price Center East, SR 2
Mon 6:00-‐6:50pm WLH 2115……. Kyra Rashid…………….. Thurs 10-‐10:40 am Revelle Commuter Lounge
Last lecture: Reflex arcs in the spinal cord Stretch reflex (monosynap0c, myota0c)
Stretch receptors in a muscle.
Ac0vates the same muscle (and agonists)
Make monosynap0c, excitatory connec0ons to motor neurons.
Makes di-‐synap0c inhibitory connec0ons that inac0vates the antagonists.
Flexion reflex
Pain receptors in the arms and legs.
Make polysynap0c, excitatory connec0ons to ac0vate flexor motor neuron.
Make polysynap0c, inhibitory connec0ons to inac0vate extensor motor neurons.
Crossed extension reflex Interneurons go across the spinal cord that make polysynap0c:
excitatory connec0ons to ac0vate extensor motor neuron.
inhibitory connec0ons to inac0vate flexor motor neurons.
Also, ways to record from the human brain: Brain electrodes (single neurons); EEG; MEG; fMRI; PET
S0mula0ng the brain
• extremely invasive
• well localized
Transcranial magne0c s0mula0on (TMS)
• non-‐invasive
• poorly localized
Focal electrical s0mula0on
(Wilder Penfield, 1959)
1. Peripheral nervous system (PNS)
Dorsal root ganglia (singular: ganglion)-‐-‐group of neurons.
Nerves-‐-‐bundles of sensory and/or motor neuron axons.
12 cranial nerves: in the head (the cranium)
30 spinal nerves: from the spinal cord
Major nerves (l/r paired) named for their origin:
Located just outside the spinal cord or near sensory organs.
Nerve branches usually named for where they end, usually in La0n.
Major components of the nervous system
1. Peripheral nervous system (PNS)
Dorsal root ganglia (singular: ganglion)-‐-‐group of neurons.
Nerves-‐-‐bundles of sensory and/or motor neuron axons.
12 cranial nerves: in the head (the cranium)
30 spinal nerves: from the spinal cord
Major nerves (l/r paired) named for their origin:
Located just outside the spinal cord or near sensory organs.
Nerve branches usually named for where they end, usually in La0n.
2. Autonomic nervous system (ANS) Ganglia, nerve networks, and nerves outside the CNS
Also includes part of the CNS
More later…..
Major components of the nervous system
Regions of the spinal cord From the back
From the side
Vertebrae
Spinal cord
Cervical cord
Thoracic cord
Lumbar cord Sacral cord
Dermatomes viewed from the front
Dermatomes viewed from the side
Spinal cord
segments
Thoracic
Cervical
Lumbar
Sacral
From: Berne & Levy Physiology, 6th Ed.