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Core 2016 Lecture II Dr. Applegate
1
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Slide 2
Basics Of Retinal Image
Quality
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Slide 3
The optics of the eye are the first stage of vision.
It is an extremely important stage but not
the only stage.
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Slide 4
The optical quality of the retinal image is defined by
pupil size and:
Diffraction
Scatter
Chromatic Aberration
Wave aberration© RAA
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Slide 5
Diffraction
“Any deviation of light rays from a rectilinear path which cannot be interpreted as reflection or refraction.”
Sommerfeld, ~ 1894
http://www.lrz.de/~Sommerfeld/Bilder/as97_01.gif
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Slide 6
Wavefronts connect points having the same phase.
Figure 5-1 from MacRae, Krueger and Applegate, Customized Corneal Ablation: The Quest for Super Vision, Slack, Inc. 2001.
© RAA
Core 2016 Lecture II Dr. Applegate
2
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Slide 7
To understand diffraction, it is necessary to understand the behavior of a wavefront
as it passes through an aperture or by edge.
© RAA
This eye can see the light.
© RAA
This eye cannot see the light.
© RAA
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Slide 10
But, the light can be dimly seen.
Light is apparently bent by the aperture.
How can this be explained?
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Slide 11
How can we explain diffraction?
Use Huygen’s Principle to explain how light bends around edges– Each point on wavefront acts as a new source of light– These new “sources” emit spherical wavefronts
• same velocity and frequency as original wavefront– These new spherical wavefronts create a secondary
wavefront– Wavefront moves forward & process repeats
Christiaan Huygens
http://ressources2.techno.free.fr/informatique/sites/inventions/inventions.html
Huygens postulated that every point on a wavefront was the
source of asecondarywavefront.
© RAA
Core 2016 Lecture II Dr. Applegate
3
For an unbounded system (no pupil), interference effects cause the light to
propagate only in the original direction.
However, for a bounded wavefront (with pupil), the effects do not cancel.
© RAA
unbounded bounded
Pupil
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Slide 14
© RAA
Light from the wavelets can reach the eye even though a straight line from the eye to the point source does not pass through the aperture.
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Slide 15
A special and particularly interesting case of Fresnel diffraction, called
Fraunhofer diffraction, occurs in the focal plane of an aberration-free or
nearly aberration-free imaging system.
The Fraunhofer diffraction pattern of an axial point source defines the
appearance of the point source in the
image plane.© RAA
Airy disc
Fraunhofer diffraction defines
the diffraction limited point spread
function (PSF).
© RAA
Diffraction - Circular Aperture
• Most relevant and important aperture shape– Shape of most lenses & apertures (like the pupil!)
• For the eye - diffraction pattern is the image of a distant point source on the retina– Also called Point Spread Function (PSF)
• Diffraction pattern (NO aberrations) consists of– central bright spot (central maximum)
• Contains majority of light (~84%)
– dimmer rings surrounding central maximum
• Airy’s Disk – contains the central maximum
Diffraction - Circular Aperture• Diffraction pattern
Aerial View 3D View
Airy’s Disk
Hecht. Optics. 2nd Ed. Addison-Wesley; 1987.Pedrotti & Pedrotti. Introduction to Optics. 2nd Ed. Prentice Hall; 1993.
Core 2016 Lecture II Dr. Applegate
4
Airy’s Disk
• How large is Airy’s Disk?
Sir George Biddel Airy: Inventor of spectacles for astigmatism
r sin 1.22d
θ = angle between peak & first minimum (in °)
λ = wavelength (in m)
d = diameter of circular aperture (in m)
dr
D
θ
Slide courtesy of Jason Porter © 2001 By Default!
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Slide 20
The diameter of the Airy disc varies with pupil diameter.
The radius of the Airy disc increases as pupil size decreases
by the following formula.
© RAA
an
fr
'
'22.1
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Slide 21
As the radius of the Airy disk decreases the higher the
fidelity of the retinal image. Said differently, in a perfect optical system the larger the pupil, the better the image.
© RAA
5 arc min.
1 mm 2 mm 3mm 4 mm
5 mm 6 mm 7 mm 8 mm
Diffraction PSFs for pupil diameters 1 - 8
© RAA
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Slide 23
Any scene is a collection of points. The image of a scene is
represented by the point spread function of every point in the
scene. So what we learn about a point image can be used to
simulate the image of an object.
© RAA
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Slide 24
Defocus = 0 D; RMS WFE = 0 mAiry disc diameter = 2.8 m
Pupil Diameter = 8.00 mm
20/12
20/20
20/40
5 arc min.
PSF
© RAA
Core 2016 Lecture II Dr. Applegate
5
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Slide 25
Pupil Diameter = 4.00 mm
20/12
20/20
20/40
Defocus = 0 D; RMS WFE = 0 mAiry disc diameter = 5.6 m
5 arc min.
© RAA
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Slide 26
Pupil Diameter = 2.00 mm
20/12
20/20
20/40
Defocus = 0 D; RMS WFE = 0 mAiry disc diameter = 11.2 m
5 arc min.
© RAA
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Slide 27
Pupil Diameter = 1.00 mm
20/12
20/20
20/40
Defocus = 0 D; RMS WFE = 0 mAiry disc diameter = 22.4 m
5 arc min.
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Slide 28
Pupil Diameter = 0.50 mm
20/12
20/20
20/40
Defocus = 0 D; RMS WFE = 0 mAiry disc diameter = 44.8 m
5 arc min.
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Slide 29
Pupil Diameter = 0.25 mm
20/12
20/20
20/40
Defocus = 0 D; RMS WFE = 0 mAiry disc diameter = 89.6 m
5 arc min.
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Slide 30
Clinical Implications of Diffraction Include:
Diffraction fundamentally defines the upper limits of retinal image quality.
Diffraction effects increase as pupil size decreases making the quality of the retinal image poorer and poorer.
© RAA
Core 2016 Lecture II Dr. Applegate
6
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Slide 31
The optical quality of the retinal image is defined by
pupil size and:
Diffraction
Scatter
Chromatic Aberration
Wave aberration© RAA
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Slide 32
Pupil
Back-scattered
Forward-scattered
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Slide 33
Type of scatter depends on particle size
Rayleigh scatter For small particles (<< wavelength of light)
– Scatter is wavelength-dependent– Short wavelengths are scattered more than longer
wavelengths– Tends to have uniform scattering in all directions
Tyndall (Mie) scatter Applies to larger particles (> wavelength of light)
– Scatter all visible wavelengths equally– Forward scattering dominates– Since all λ’s scattered the same, causes object to look
white (or some saturation of white)
4
1Scatter
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Slide 34
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Slide 35 © 2001 By Default!
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Slide 36
20/25 VA
Slitlamp Cross-section -
CataractRetro-Illumination -
Cataract© RAA
Core 2016 Lecture II Dr. Applegate
7
Tom van den Berg Tom van den Berg
Tom van den Berg
Ciliary corona
Actual subjective appearance of straylight: a pattern of very fine streaks, not at all like the circularly uniform (Airy disc-
like) scattering pattern of particles of approximate wavelength size
Tom van den Berg
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Slide 41
The optical quality of the retinal image is defined by
pupil size and:
Diffraction
Scatter
Chromatic Aberration
Wave aberration© RAA
The speed of light in in the eye varies with the wavelength of light. The
shorter the wavelength the slower the speed of light. Since the index of
refraction is the ratio of the speed of light in a vacuum to the speed of light
in the new medium, the index of refraction is greater for short
wavelengths than it is for longerwavelengths.
© RAA
Core 2016 Lecture II Dr. Applegate
8
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Slide 43
As light enters the eye, the higher the refractive index the greater the angle of refraction
as dictated by Snell’s law.
© RAA
'sin'sin inin
i
'in 'n
The speed of light in a material is dependent on refractive index
• Most materials exhibit dispersion, or a change in the index of refraction with wavelength
• What does dispersion imply about the following properties for different wavelengths in a material:– Velocity
n
high
lowshort long
Positive chromaticaberration
velocity c(speedoflight)
n
Shorter wavelengths: higher nslower velocity Slide courtesy of Jason Porter
The speed of light in a material is dependent on refractive index
• Most materials exhibit dispersion, or a change in the index of refraction with wavelength
• What does dispersion imply about the following properties for different wavelengths in a material:– Velocity– Angle of refraction
n
high
lowshort long
Positive chromaticaberration
n*sini n' *sini'i
nn'
i'Shorter wavelengths: higher n’
smaller i’ – greater refractionSlide courtesy of Jason Porter
The speed of light in a material is dependent on refractive index
• Most materials exhibit dispersion, or a change in the index of refraction with wavelength
• What does dispersion imply about the following properties for different wavelengths in a material:– Velocity– Angle of refraction– Power of a surface
n
high
lowshort long
Positive chromaticaberration
F n' nr
i
n n'Shorter wavelengths: higher n’higher power
Slide courtesy of Jason Porter
© RAA
Longitudinal (Axial) Chromatic Aberration
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Slide 48
1D
The difference in longitudinal chromatic aberration between 486 and 656 nm is just over 1 D.
Adapted from Bennet & Rabbetts, 1989© RAA
Core 2016 Lecture II Dr. Applegate
9
Transverse Chromatic Aberration
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Slide 50
The optical quality of the retinal image is defined by
pupil size and:
Diffraction
Scatter
Chromatic Aberration
Wave aberration© RAA
Simple Myopia© RAA
Simple Myopia with Optical Correction
© RAA
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Slide 53
In reality it is not so simple.
© RAA © RAA
Core 2016 Lecture II Dr. Applegate
10
© RAA
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Slide 56
The eye has higher order wave aberrations that become increasingly manifest as the pupil diameter increases.
© RAA
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Slide 57
1mm 2mm 3mm 4mm
Diffraction-Limited System
Normal Eye with
Typical Aberrations
5mm 6mm 7mm 8mm© RAA
Diffraction-Limited System
Normal Eye with
Typical Aberrations
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Slide 58
For many clinical eyes (ie. keratoconics), it is important to
correct the higher order aberrations.
For the normal eye, the gains obtained by correcting higher
order aberrations are primarily for large pupil sizes and diminish as
the pupil size gets small.
© RAA
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Slide 59
In the past, a patient’s eye which could not be corrected
with conventional sphero-cylindrical corrections, was
often dismissed with a diagnosis of irregular astigmatism.
We are now in a position to attempt to correct these eyes.
© RAA
Larry Thibos has written a basic level article on wavefront sensing
and its advantages
• http://journals.lww.com/optvissci/Fulltext/2013/09000/The_2012_Charles_Prentice_Medal_Lecture__.4.aspx
• http://links.lww.com/OPX/A134
Core 2016 Lecture II Dr. Applegate
11
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Slide 61
Wavefront
Wavefront error.
The specification of wavefront error.
RMS WFE– By mode, age, pupil diameter
Visual image quality metrics derived from WFE
© RAA
With this overview in mind let’s exam:
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Slide 62
To understand the need for the measurement of
wavefront error in the correction of refractive
errors, it is helpful to change our thinking from rays of
light to waves of light.
© RAA
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Slide 63
Rays
© RAA
Wavefronts
Focus
Wavefront After Refraction
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Slide 64
Wavefront
Wavefront error.
The specification of wavefront error.
RMS WFE– By mode, age, pupil diameter
Visual image quality metrics derived from WFE
© RAA
With this overview in mind let’s exam:
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Slide 65
Ideal Aberrated
Rays
© RAA
Waves and Rays
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Slide 66
© RAA
Wavefront error is the difference
between the ideal wavefront and
the actual wavefront.
Core 2016 Lecture II Dr. Applegate
12
perfectretinal
image ofobject point
P
Unaberrated Eye focused for distance
Key points:
• All rays from P intersect at common point P on the retina.
• The optical distance from object P to image P is the same for all rays.
• Wavefront converging on retina is spherical.
Rays from distant object point, P.
Slide courtesy Larry Thibos
Aberrated eye
Key points:
• Rays do NOT intersect at the same retinal location.
• The optical distance from object to retina is NOT the same for all rays. OPD = Optical Path Difference
• Wavefront is NOT spherical.
Pflawedretinalimage
Rays from distant point source, P. P
Slide courtesy Larry Thibos
Plane wave
Spherical wave Aberrated wave
Ideal, Perfect Eye Normal, Aberrated Eye
Wavefront error is the difference between the ideal wavefront and the actual wavefront.
Slide courtesy of Jason Porter © 2001 By Default!
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Slide 70
Wavefront
Wavefront error.
The specification of wavefront error.
RMS WFE– By mode, age, pupil diameter
Visual image quality metrics derived from WFE
© RAA
With this overview in mind let’s exam:
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Slide 71
A particularly useful (but not the only) representation of ocular
aberration is to fit the error between the actual wavefront and the ideal
wavefront in three dimensions with a Zernike expansion.
Fitting the error data with a Zernike expansion parcels the error into
unique building blocks.© RAA
-4 -3 -2 -1 0 1 2 3 4
0
1
2
3
4
nm
n
mZ
© RAA
2
0Z
Core 2016 Lecture II Dr. Applegate
13
-1 0 1
0
1n
m
The 0 and 1st radial orders of the Zernike expansion are generally ignored when measuring the monochromatic optical aberrations of the fixating eye. The reason is simple, neither affect the image quality of the fixating eye. The 0 radial order simply adds a constant to all locations and the 1st radial order are prism terms affecting the position but not the optical quality of the image.
0
0Z
1
-1Z 1
1Z
Z
© RAA
-2 -1 0 1 2
0
1
2
n m
Zn
m
The 2nd radial order in the Zernike expansion the traditional ophthalmic prescription.
reflect the spherical (defocus) error. and together reflect the cylindrical error.1
2Z 1
2Z
02Z
2
-2Z 2
0Z 2
2Z
© RAA
-4 -3 -2 -1 0 1 2 3 4
0
1
2
3
4
nm
n
m
Zernike Expansion modes in the 3rd order and higher are collectively called the higher order aberrations.
Z
© RAA
0
3 4 5
6 7 8 9
10 11 12 13 14
1 2
© RAA
2
3
DefocusAstigmatism Astigmatism
VerticalComa
HorizontalComa
SphericalAberration
Trefoil Trefoil
Tetrafoil Secondary Astigmatism
Secondary Astigmatism
Tetrafoil
4
-4 -3 -2 -1 0 1 2 3 4n
m
nm
Z
© RAA
Each mode’s magnitude (weight) is defined by a coefficient C having the same sub-
script and superscript as the Zernike mode.
Four different magnitudes of secondary astigmatism.
4-2C 4
-2Z
4
-2C = 0.3μ 4
-2C = 0.2μ 4
-2C = 0.1μ 4
-2C = 0.05μ
© RAA
Core 2016 Lecture II Dr. Applegate
14
+ +
+ + +
+ + + +
=
Weighted Zernike modes through the 4th radial order in this PRK eye for a 6mm pupil are added together linearly to form the representation
of the total wavefront error.© RAA
2
3
DefocusAstigmatism Astigmatism
SphericalAberration
Trefoil Trefoil
Tetrafoil Secondary Astigmatism
Secondary Astigmatism
Tetrafoil
4
-3 -2 0-1-4 1 2 3 4Angular Frequency
Sine Cosine
VerticalComa
HorizontalComa
© RAA
+
To determine the magnitude and orientation of any given aberration that has an angular frequency other than zero, the sine and cosine modes for the aberration of interest are added. For example, vertical coma (sine mode) and horizontal coma (cosine mode) can be added together to establish the total magnitude and orientation of coma.
=
3
-1Z
Vertical Coma Horizontal Coma
© RAA
C3
-1
3
1ZC3
1
Total Coma
+ +
+ + +
+ + + +
=
2
3
4
n m 0 1 2 3 4-3 -2 -1-4
Sine Cosine
Thus, astigmatism modes can be added together, trefoil modes can be added together, coma modes can be added together, tetrafoil
modes can be added together, secondary astigmatism modes can be added together, etc.
© RAA
+
=++
+++
Defocus Astigmatism Trefoil Coma
Tetrafoil SecondaryAstigmatism
SphericalAberration
TotalAberration
It can easily be seen that this post PRK eye aberrations are primarily dominated by coma, spherical aberration, secondary astigmatism,
trefoil and a smaller amounts of defocus, astigmatism, and tetrafoil.
© RAA
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Slide 84
How are aberrations distributed in the population?
and
What is the best way to display ocular aberrations in a meaningful
way?
Core 2016 Lecture II Dr. Applegate
15
Smirnov HS (1961). Measurement of the wave aberration in the human eye. Biophys6:52-66
“The method applied in the present work of determining the wave aberration is quite laborious; although the measurements can be taken in 1‐2 hours, the calculations take 10‐12 hours… Therefore, it is unlikely that such detailed measurements will ever be adopted by practitioner‐ophthalmologists.”
Slide courtesy of Jason Porter
Howland HC and Howland B (1977). A subjective method for the measurement of monochromatic aberrations of the eye. J Opt Soc Am, 67:1508-1518
55 eyes from 33 subjects
Howland & HowlandSmirnov
The means of almost all Zernike modes are approximately zero and have a
large intersubject variability
Mean of 109 subjects5.7 mm pupil
Mic
ron
s o
f A
ber
rati
on
Zernike Mode
-2
0
2
4
6
8
Z20 Z 2
-2 Z22 Z 3
-1Z31 Z 3
-3 Z33 Z4
0 Z42 Z 4
-2 Z44 Z 4
-4 Z51 Z 5
-1Z53Z 5
-3 Z55 Z 5
-5
Z 3-1 Z3
1 Z 3-3 Z3
3 Z40 Z4
2 Z 4-2 Z4
4 Z 4-4 Z5
1 Z 5-1 Z5
3 Z 5-3 Z5
5-0.3
-0.2
-0.1
0
0.1
0.2
0.3
Z 5-5
Spherical aberration
Porter et al., JOSA A (2001)
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Slide 88
-0.6
-0.5
-0.4
-0.3
-0.2
-0.1
0
0.1
0.2
0.3
0.4
0.5
0.6
C6 C7 C8 C9 C10 C11 C12 C13 C14 C15 C16 C17 C18 C19 C20 C21 C22 C23 C24 C25 C26 C27
Co
eff
icie
nt
Va
lue
in m
icro
met
ers
All Patients
7mm pupil
3rd 4th 5th 6th
TINCO Study Patients age > 20 < 82; N = 113
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Slide 89
The reason that the average coefficient value approaches zero
is that for most modes of the Zernike expansion there are some eyes where the coefficient has a
negative sign and in others it has a positive sign.
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Slide 90
This similar to saying that the following group of individuals on average have no refractive error.
Subject # Correction Subject # Correction
1 -2 6 2
2 -10 7 10
3 -5 8 5
4 -6 9 6
5 -15 10 15
Ave. = 0
Core 2016 Lecture II Dr. Applegate
16
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Slide 91
Wavefront
Wavefront error.
The specification of wavefront error.
RMS WFE– By mode, age, pupil diameter
Visual image quality metrics derived from WFE
© RAA
With this overview in mind let’s exam:
© 2001 By Default!
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Slide 92
On the other hand if we had looked at magnitudes we would have
found the average magnitude of the refractive error to be 7.60 D not
zero.
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Slide 93
0
0.1
0.2
0.3
0.4
0.5
0.6
C6 C7 C8 C9C10
C11C12
C13C14
C15C16
C17C18
C19C20
C21C22
C23C24
C25C26
C27
Mag
nit
ud
e W
avef
ron
t E
rro
rin
mic
rom
eter
s
All Patients
7mm pupil
TINCO Study Patients age > 20 < 82; N = 113
3rd 4th 5th 6th
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Slide 94
Magnitude of the wavefront error for any Zernike mode is
equivalent to the RMS wavefront error for that mode.
)(2 CabsCtermanyforerrorwavefrontRMS
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Slide 95
RMS wavefront error is equivalent to the standard
deviation of the wavefront error over the pupil.
2
3
DefocusAstigmatism Astigmatism
SphericalAberration
Trefoil Trefoil
Tetrafoil Secondary Astigmatism
Secondary Astigmatism
Tetrafoil
4
-3 -2 0-1-4 1 2 3 4Angular Frequency
Sine Cosine
VerticalComa
HorizontalComa
© RAA
Core 2016 Lecture II Dr. Applegate
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Slide 97
-0.6
-0.4
-0.2
0
0.2
0.4
0.6
0.8
C6 C7 C8 C9 C10 C11 C12 C13 C14
Co
eff
icie
nt
Va
lue
in m
icro
met
ers
3rd 4th
TICO Study Patients age > 20 < 82; N = 113
Coma
TrefoilS
ph
. Ab
2nd Astig.
Tetrafoil
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Slide 98
RMS error trefoil =
RMS error coma =
RMS error tetrafoil =
RMS error 2nd astig. =
213
213 )()( CC
233
233 )()( CC
244
244 )()( CC
224
224 )()( CC
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Slide 99
TICO Study Patients age > 20 < 82; N = 113
0
0.05
0.1
0.15
0.2
0.25
0.3
0.35
0.4
RM
S E
rro
rin
mic
rom
eter
s
Trefoil Coma Tetrafoil 2nd Astig Sph Ab
7mm pupil
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Slide 100
While RMS plots of each type of aberration tell us how much and
which aberrations are contributing to the typical aberration structure,
such plots do not tell us the orientation of the aberration, or
how aberrations interact to increase or decrease visual
performance.
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Slide 101
Aberrations for any given person vary as a function of several
factors including:
Age
Pupil diameter
Tear quality between blinks
Accommodation
Optical disease and conditions that affect ocular optical quality (CLs, refractive surgery, IOLs, etc.)
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Slide 102
The most common metric of wavefront aberration is total high order RMS wavefront error. RMS
wavefront error is equivalent to the standard deviation of the high order wavefront over the pupil
aperture.
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Core 2016 Lecture II Dr. Applegate
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Slide 103
High order RMS aberration as a function of pupil size and age
0
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© 2006 Applegate
Applegate, RA, Donnelly, WJ III, Marsack, JD, Pesudovs, K, The 3-D relationship between high order RMS wavefront error, pupil diameter, and aging, J Opt Soc Am-A, 24:578-587, 2007.
© 2006 Applegate
Applegate, RA, Donnelly, WJ III, Marsack, JD, Pesudovs, K, The 3-D relationship between high order RMS wavefront error, pupil diameter, and aging, J Opt Soc Am-A, 24:578-587, 2007.
Figure 3A.
© 2006 Applegate
Applegate, RA, Donnelly, WJ III, Marsack, JD, Pesudovs, K, The 3-D relationship between high order RMS wavefront error, pupil diameter, and aging, J Opt Soc Am-A, 24:578-587, 2007.
Figure 3A.
Applegate, RA, Donnelly, WJ III, Marsack, JD, Pesudovs, K, The 3-D relationship between high order RMS wavefront error, pupil diameter, and aging, J Opt Soc Am-A, 24:578-587, 2007. Applegate, RA, Donnelly, WJ III, Marsack, JD, Pesudovs, K, The 3-D relationship between high order
RMS wavefront error, pupil diameter, and aging, J Opt Soc Am-A, 24:578-587, 2007.
Core 2016 Lecture II Dr. Applegate
19
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Slide 109
For any given Zernike aberration visual performance
decreases as the RMS WFE increases.
For the optometrists amongst you the following simulations illustrate why
dioptric error can be very misleading
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Slide 110
The following simulations fix the dioptric error of the eye at
0.25 D. Notice in these simulations that as pupil size
decreases so does RMS wavefront error despite the fact
that the dioptric defocus remains constant.
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Slide 111
Pupil Diameter = 2.00mm
Defocus = 0.25DRMS wave aberration = 0.036 µm
20/12
20/20
20/40
© RAA
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Slide 112
Pupil Diameter = 4.00mm
Defocus = 0.25DRMS wave aberration = 0.14 µm
20/12
20/20
20/40
© RAA
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Slide 113
Pupil Diameter = 8.00mm
Defocus = 0.25D RMS wave aberration = 0.58 µm
20/12
20/20
20/40
© RAA
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Slide 114
In this case, wavefront error tells us that the image is getting better or worse, dioptric error does not.
© RAA
0.58µm WFE 0.036µm WFE
8.0mm pupil 0.25D Myope 2.0mm pupil
Core 2016 Lecture II Dr. Applegate
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Slide 115
Wavefront
Wavefront error.
The specification of wavefront error.
RMS WFE– By mode, age, pupil diameter
Visual image quality metrics derived from WFE
© RAA
With this overview in mind let’s exam:Unfortunately changes in RMS WFE are not always well correlated to changes in
visual performance.
Applegate, RA, Sarver, EJ, Khemsara, V, Are All Aberrations Equal? Journal of Refractive Surgery, 18:S556‐S562, 2002.
2nd
3rd
4th
-4 -3 -2 -1 0 1 2 3 4
RMS = 0.25 μ over a 6mm pupil, Equiv. D = 0.19 D Letter size 20/40
Applegate, RA, Sarver, EJ, Khemsara, V, Are All Aberrations Equal? Journal of Refractive Surgery, 18:S556-S562, 2002. © RAA
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RMSUH © RAA
Applegate, RA, Sarver, EJ, Khemsara, V, Are All Aberrations Equal? Journal of Refractive Surgery, 18:S556-S562, 2002.
RMS = 0.25 μ6mm pupilEquiv. D = 0.19 D
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Core 2016 Lecture II Dr. Applegate
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-14
-12
-10
-8
-6
-4
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y = -12.684 + 20.513x R 2= 0.80928
Visual Strehl
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Interaction between aberrations can improve or reduce visual performance, Journal Cataract and Refractive Surgery, 29:1487‐1495, 2003.
Single valued metrics of optical quality derived from wave aberration predict visual performance, Journal of Vision, 4:322‐328. 2004
+ =
0.25 µ+
=22 15.02.0 Applegate, RA, Marsack, J., Ramos, R., Interaction Between Aberrations Can Improve or
Reduce Visual Performance, J Cataract and Refractive Surgery, 29:1487-1495, 2003
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The Visual Strehl
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Six just noticeable differences in retinal image quality in one line of visual acuity: Towards quantification of ‘20/20 happy’ vs. ‘20/20 unhappy’, Journal of Cataract and Refractive Surgery, 37:1523–1529, 2011.
Core 2016 Lecture II Dr. Applegate
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In this paper, Ravikumar et al reported the visual Strehl could distinctly quantify 6 just noticeable changes in blur prior to a 1 line
loss of logMAR acuity.
Given the task in a subjective refraction is to say which is better # 1 or #2, this results suggests that the visual Strehl can be used to objectively define the sphere cylinder and axis that best balances an individuals higher order aberrations.
Change in visual acuity is highly correlated with change in image quality metrics independent of wavefront error and/or pupil diameter, Journal of Vision, 12:1‐13, 2012.
Change in log VSX
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Change in logMAR = - 0.453 * Change in log VSX -0.0877r2 = 0.87, p < 0.001
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