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IACAPAP 2012 – 20th World congress / Neuropsychiat

ffects of MCT on social communicative behaviors of older children with ASD’smean age 6 years, 10 months) utilizing a group design with randomized treat-ent and waitlist control. Inclusion criteria were less than 10 spontaneous words,

imited reciprocity, gesture, eye contact, and joint attention, and the interventionas 32 weeks. Data was analyzed at pretest, posttest, and follow-up utilizing

ffect sizes for individual differences on specified prelinguistic behaviors, andarticipants were compared to an age and ability matched waitlist control group.ata indicated large effect sizes and significant differences were noted betweenroups.

ttp://dx.doi.org/10.1016/j.neurenf.2012.04.456

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evised early screening tools of social cognitive disabilityor preschool children. Jin ∗, J. Jing

Faculty Of Child And Maternal Health, Public Health school of Sun Yat-senniversity, Guangzhou, China

Corresponding author.

bjective.– To revised and investigate the reliability and validity of the Chineseersion of Theory of Mind Test (TOMT).ethods.– A total of 1098 preschool children and 41 children with suspected

iagnose of Pervasive Developmental Disorders (PDD) completed TOMT. Theeliability and validity of TOMT were evaluated.esults.– The test-retest reliability of expression recognition, expression attri-ution, unexpected place tests and unexpected content test were 0.98,0.92, 0.76,.75 (P < 0.01), respectively. The Cronbach’s � coefficients between each sub-ests of TOMT was 0.75 (P < 0.01). Kappa coefficients of TOMT and diagnosef PDD was 0.75 (P < 0.01).onclusion.– The Chinese version of TOMT was found to have good psychome-

rics properties and is applicable to assess social cognition disability of Chinesereschool children.

ttp://dx.doi.org/10.1016/j.neurenf.2012.04.457

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song about Asperger’s syndrome: a psychoeducationalontribution. Bessa Marques Filho

Psychiatry, Faculdade de Medicina de São José do Rio Preto (FAMERP), Sãoosé do Rio Preto, SP, Brazil

bjective.– To verify whether a song with didactic purpose about Asperger’syndrome can be useful in psychoeducation programs.ethod.– A music was co-written by the author, José Celso Colturato Barbeiro

nd Emerson Martini; lyrics describing Asperger’s Syndrome was composed byhe author; the resulting song was illustrated by Vladimir Vaz with drawingsnd legends; a ten questions about Asperger’s syndrome was formulated, askingnswers: “yes”, “no” and “I don’t Know”; this questionnaire was aplicated beforend after the presentation of the video containing the song, named “Asperger’song” presented to students in first year courses of medicine and nursing.esults.– Various symptoms of Asperger syndrome are presented in the formf verses; the sample demonstrated significant improvements in the averageesponses to the questionnaire after watching the presentation of music.onclusions.– Popular songs done with didactic purpose can be used as anducational resource psychoeducational programs.

ttp://dx.doi.org/10.1016/j.neurenf.2012.04.458

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utism spectrum disorder and genetic syndromes:pplication of novel genetic knowledge for geneticiagnosis

. Ducloy a,∗, M. Bouvard b, F. Galibert c

Centre ressource autisme, centre hospitalier Charles-Perrens, universitéordeaux II Ségalen, Bordeaux, France

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l’enfance et de l’adolescence 60S (2012) S197–S253 S213

Pôle universitaire de psychiatrie de l’enfant et de l’adolescent, hôpitalharles-Perrens, Bordeaux, FranceUniversité de Rennes 1, institut génétique et développement de Rennes, IFR40, Rennes, FranceCorresponding author.

utism Spectrum Disorder (ASD) is a neurodevelopmental abnormality causedy genetic, environmental and epigenetic unknown factors. Presently 10% ofSD have a diagnosed genetic abnormality. In a cohort of 94 patients consul-

ing in Centre Resource Autism, in Aquitaine, France between 2006 and 2011,first systematic genetic screening including caryotype, fragil-X, 22q11 and

2qter microdeletion research showed 7.3% of genetic abnormalities. The aimf our study was to check whether additional analysis would permit to diagnosether genetic mutations. According to clinical observation, a second set of gene-ic analysis was performed including CGH-array, MECP2, ARX, FDN1, PLP,UMF1 mutation, 7q11.23, 12q, 1p36, microdeletion research. Following thistudy, we observed 17.1% of ASD children had a genetic diagnosis. The studyhows that new genetic techniques selected based on clinical observation allowso detect additional genetic impairment and to propose a pre-natal diagnosis toregnant of ASD infant.

ttp://dx.doi.org/10.1016/j.neurenf.2012.04.459

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utism spectrum disorder; exploring the boundaries. Wouters ∗, A. Lampo

Child Psychiatry, UZ Brussel, Brussels, BelgiumCorresponding author.

linical and biological evidence for links between Autism/Autism Spectrumisorder (ASD) and Schizophrenia is emerging. As DSM-5 will narrow diag-ostic criteria for ASD, it’s leaving clinicians with a heterogeneous group ofhildren who experience severe impairment in both social and global functio-ing and don’t meet diagnostic syndromal criteria. Working in the “Referenceenter for Autism” (RCA) and in the inpatient unit at the Universitary Hos-ital, Brussels, Belgium, confronts us on a daily basis with the boundaries ofur current view on autistic and developmental disorders. The center evaluatespproximately 120 new outpatients and 80 inpatients a year. In our in-patient cli-ic, we treat several of these high-care children. Clinical, demographic, geneticnd neurological data of a group of patients (n = 10) was reviewed. By describingheir characteristics, we would like to point out current diagnostic difficulties.ifferentiation between ASD and Childhood Schizophrenia is indeed challen-ing. It becomes more and more clear that long term follow-up of at risk childrennd adolescents and cooperation between child and adult psychiatrists is neededo learn more and enhance diagnostic distinction at an early age.

ttp://dx.doi.org/10.1016/j.neurenf.2012.04.460

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ay the autism diagnoctic observation scale (ADOS) be aransitional device?. Taly ∗, G. Malburet

Loroux-Bottereau, FranceCorresponding author.

ith the support of the Regional Autism Resource Center (CRERA) of Angers,ur child psychiatry service of Nantes Sud-Loire discovers and is trained forutism diagnosis with tools recommended by the High Authority for HealthHAS) and recognized at an international level, such as Autism Diagnostic Inter-iew (ADI) and Autism Diagnostic Observation Scale (ADOS). However, thesychoanalytical theoretic base of the service leads the clinicians to engagen a broader analysis of the collected material where the ADOS tool can alsoe understood like a transitional device. Indeed, the incentives to play whichunctuate the test; the taking into account of the inter-subjective dimension ofhe encounter with its emotional nuances gives depth and enriches the scoring

ndex. To illustrate this, the authors propose a clinical study of a 4-year old childresenting an autistic spectrum disorder evaluated with ADOS- module 1.

ttp://dx.doi.org/10.1016/j.neurenf.2012.04.461