Are We Reaching the Children? Issues in Pediatric HIV Programming Anouk Amzel, MD, MPH Jacqueline Firth, MD, MPH Office of HIV/AIDS USAID March 7, 2014

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Are We Reaching the Children? Issues in Pediatric HIV Programming Anouk Amzel, MD, MPH Jacqueline Firth, MD, MPH Office of HIV/AIDS USAID March 7, 2014 9:45am Slide 2 Outline Epidemiology of Pediatric HIV Perinatal Infection and Implications Prevention of Infant Infections How are infant infections different from adult infections? Where Can HIV-positive children be found? Adolescents Living with HIV Starting and Keeping Children and Adolescents LHIV on Treatment Treatment of Children and Youth with HIV Retention in Care and Treatment Programs Slide 3 Epidemiology Slide 4 Children and HIV How many new HIV infections occurred among children (0-14 years) in low- and middle-income countries in 2012? What percentage of HIV-infected children received ART in 2012? What percentage of infants living with HIV will die before their first birthday without treatment? Before their second birthday? Towards an AIDS-Free Generation: Children and AIDS 6 th Stocktaking Report 2013, UNICEF, Nov. 2013 260,000 34% One-third Half Slide 5 Where are Children Living with HIV? Slide 6 The Good News Slide 7 Prevention of infant infections Slide 8 BREASTFEEDING POPULATION Overall cumulative risk MTCT (without antiretroviral drugs): 40-45% Timing of MTCT >28 wks Labor- Delivery 35-40% 1-6 mos6-24 mos0-1 mo Pregnancy 10-25%