Anatomy presentation ho 6(circulation)

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    rcu a ory sys em The circulatory system transports fluids throughout the body;

    it consists of the cardiovascular and lymphatic systems.

    The heart and blood vessels form the blood transportation network,

    the CVS

    The function of the circulation

    to transport nutrients to the body tissues,

    to transport waste products away,

    to conduct hormones from one part of the body to another

    Cardiovascular System

    is a series of tubes (the blood vessels) filled with fluid (blood) and

    connected to a pump (the heart). Refers to the heart and blood vessels

    The heart pumps blood through the body's vast system of vessels.

    The blood carries nutrients, oxygen, and waste products to and from

    cells. Blood flows through a network of blood vessels that extend between

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    Those blood vessels can be subdivided into

    pulmonary circuit

    which carries blood to and from the gas exchange surfaces of

    the lungs, and systemic circuit

    which transports blood to and from the rest of the body.

    Each circuit begins and ends at the heart and blood travels through

    these circuits in sequence.

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    Blood Vessels: The VascularBlood Vessels: The VascularSystemSystem

    Slide

    Taking blood to the tissues and back

    ArteriesArterioles

    Capillaries

    Venules

    Veins

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    The Vascular SystemThe Vascular System

    Slide

    Figure 11.8b

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    Blood Vessels: AnatomyBlood Vessels: Anatomy

    Slide

    Three layers (tunics)Tunic intima

    Endothelium

    Tunic media

    Smooth muscle

    Controlled by sympathetic nervous

    system

    Tunic externa

    Mostly fibrous connective tissue

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    Differences Between Blood VesselDifferences Between Blood VesselTypesTypes

    Slide

    Walls of arteries are the thickest

    Lumens of veins are larger

    Skeletal muscle milks blood in veinstoward the heart

    Walls of capillaries are only one celllayer thick to allow for exchangesbetween blood and tissue

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    Movement of Blood ThroughMovement of Blood ThroughVesselsVessels

    Slide

    Most arterial blood is

    pumped by the heart Veins use the milking

    action of muscles to

    help move blood

    Figure 11.9

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    Capillary BedsCapillary Beds

    Slide

    Capillary bedsconsist of two

    types of vessels

    Vascular shunt directly connects an

    arteriole to a venule

    Figure 11.10

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    Capillary BedsCapillary Beds

    Slide

    True capillaries exchange vessels

    Oxygen andnutrients cross tocells

    Carbon dioxide

    and metabolicwaste productscross into blood

    Figure 11.10

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    Diffusion at Capillary BedsDiffusion at Capillary Beds

    Slide

    Figure 11.20

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    Vital SignsVital Signs

    Arterial pulseArterial pulse

    Blood pressureBlood pressure

    Repiratory RateRepiratory Rate

    Body TemperatureBody Temperature

    All indicate the efficiency of theAll indicate the efficiency of thesystemsystem

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    PulsePulse

    Slide

    Pulse pressure wave

    of blood Monitored at

    pressure

    points wherepulse is easilypalpated

    Figure 11.16

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    Blood PressureBlood Pressure

    Slide

    Measurements by health professionalsare made on the pressure in largearteries

    Systolic pressure at the peak ofventricular contraction

    Diastolic pressure when ventricles relax

    Pressure in blood vessels decreases asthe distance away from the heartincreases

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    Measuring Arterial Blood PressureMeasuring Arterial Blood Pressure

    Slide

    Figure 11.18

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    Blood Pressure: Effects of FactorsBlood Pressure: Effects of Factors

    Slide

    Neural factors

    Autonomic nervous system adjustments

    (sympathetic division) Renal factors

    Regulation by altering blood volume

    Renin hormonal control

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    Blood Pressure: Effects of FactorsBlood Pressure: Effects of Factors

    Slide

    Temperature

    Heat has a vasodilation effect

    Cold has a vasoconstricting effect

    Chemicals

    Various substances can cause increases ordecreases

    Diet

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    Variations in Blood PressureVariations in Blood Pressure

    Slide

    Human normal range is variableNormal

    140110 mm Hg systolic

    8075 mm Hg diastolic

    Hypotension

    Low systolic (below 110 mm HG)

    Often associated with illness

    Hypertension

    High systolic (above 140 mm HG)

    Can be dangerous if it is chronic

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    The lymphatic system

    Includes: lymph, lymphatic vessels, lymphatic tissue, lymphatic nodules, lymph nodes,

    tonsils, the spleen, and the thymus.

    The major functions of the lymphatic system include

    fluid balance,

    fat absorption, and

    defense.

    Recall that as blood flows thru systemic capillaries, a small net amount of fluid is exuded

    into the interstitial space.

    While this fluid loss from the capillaries is necessary to maintain the presence and

    composition of tissue fluid (and thus intracellular fluid as well), too much fluid loss is not a

    good thing.

    Luckily, we have lymphatic vessels, whose main function is to return this fluid to the

    vascular system.

    Additionally, they play a huge role in detecting pathogens and activating the appropriate

    immune response.

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    Lymphatic vessels

    return approximately 3L of fluid to the vascular system per day.

    This ensures that blood volume is sufficient.

    They also return any leaked plasma proteins back to the bloodstream.

    Fluid within lymphatic vessels is known as lymph.

    Lymph

    is similar to plasma except it contains fewer proteins.

    It contains water, nutrients, ions, gases, wastes, and hormones.

    Lymphatic vessels are a 1-way system flowing toward the heart. There are several types of lymphatic vessels including: lymphatic capillaries,

    lymphatic collecting vessels, lymphatic trunks, and lymphatic ducts.

    Lymphatic capillaries

    are blind capillaries found almost everywhere blood capillaries are found, i.e.,

    everywhere tissue fluid is formed.

    Areas w/o lymphatic capillaries include bones, teeth, and CNS.

    Little ISF is found w/i bones and teeth.

    CNS ISF drains into the cerebrospinal fluid.

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    The simple squamous epithelial cells of the capillary wall overlap and are loosely

    attached to another.

    This makes the lymphatic capillaries quite permeable (much more so than blood

    capillaries) and ensures that fluid is able to enter but not leave.

    Fluid enters easily, as do proteins, WBCs, pathogens, and cancer cells.

    Specialized lymphatic capillaries, known as lacteals, are present in the intestinal

    mucosa where they assist in absorption of dietary fat.

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    Lymphatic collecting vessels

    receive lymph from lymphatic capillaries.

    Theyre similar to veins (tunics with similar proportions) but contain more valves.

    There exist both superficial and deep lymphatic collecting vessels.

    They pass thru lymph nodes, where lymph is monitored and cleaned of pathogens

    and cancer cells.

    Lymphatic trunks

    The union of the largest lymphatic vessels .

    The jugular trunks drain the head and neck; the subclavian trunks drain the upper limbs, superficial thoracic wall, and mammary

    glands;

    the bronchomediastinal trunks drain thoracic organs and the deep thoracic wall;

    the intestinal trunks drain the intestines, stomach, pancreas, spleen, and liver; and

    the lumbar trunks drain the lower limbs, pelvic and abdominal walls, pelvic organs,

    gonads, kidneys, and adrenal glands.

    Lymphatic duct

    The union of lymphatic trunks

    There are 2 lymphatic ducts: the right lymphatic duct and the thoracic duct.

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    The right lymphatic duct

    drains lymph from the right arm and the right side of the head and thorax.

    It receives lymph from the right jugular, right subclavian, and right

    bronchomediastinal trunks.

    It then empties into the right internal jugular vein.

    The thoracic duct

    drains lymph from the rest of the body.

    It receives lymph from the left jugular, left subclavian, left bronchomediastinal,

    intestinal, and lumbar trunks. It empties into the left internal jugular vein.

    Note that there is a large degree of variability in the formation and emptying of

    the lymphatic ducts.

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    LymphLymph

    SlideCopyright 2003 Pearson Education, Inc. publishing as Benjamin Cummings

    Materials returned to the blood

    WaterBlood cells

    Proteins

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    LymphLymph

    SlideCopyright 2003 Pearson Education, Inc. publishing as Benjamin Cummings

    Harmful materials that enter lymphvessels

    Bacteria

    Viruses

    Cancer cells

    Cell debris

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    Lymph NodesLymph Nodes

    SlideCopyright 2003 Pearson Education, Inc. publishing as Benjamin Cummings

    Filter lymph before it is returned to theblood

    Defense cells within lymph nodes

    Macrophages engulf and destroy foreignsubstances

    Lymphocytes provide immune response toantigens

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    Lymph NodesLymph Nodes

    SlideCopyright 2003 Pearson Education, Inc. publishing as Benjamin Cummings

    Figure 12.3

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    Lymph Node StructureLymph Node Structure

    SlideCopyright 2003 Pearson Education, Inc. publishing as Benjamin Cummings

    Figure 12.4

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    Other Lymphoid OrgansOther Lymphoid Organs

    Slide 12.9Copyright 2003 Pearson Education, Inc. publishing as Benjamin Cummings

    Several otherorgans contributeto lymphatic

    functionSpleen

    Thymus

    Tonsils

    Peyers patchesFigure 12.5

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    The SpleenThe Spleen

    SlideCopyright 2003 Pearson Education, Inc. publishing as Benjamin Cummings

    Located on the left side of the abdomen

    Filters blood

    Destroys worn out blood cells

    Forms blood cells in the fetus

    Acts as a blood reservoir

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    The ThymusThe Thymus

    SlideCopyright 2003 Pearson Education, Inc. publishing as Benjamin Cummings

    Located low in the throat, overlying theheart

    Functions at peak levels only duringchildhood

    Produces hormones (like thymosin) toprogram lymphocytes

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    TonsilsTonsils

    SlideCopyright 2003 Pearson Education, Inc. publishing as Benjamin Cummings

    Small masses of lymphoid tissuearound the pharynx

    Trap and remove bacteria and otherforeign materials

    Tonsillitis is caused by congestion withbacteria

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    Peyers PatchesPeyers Patches

    SlideCopyright 2003 Pearson Education, Inc. publishing as Benjamin Cummings

    Found in the wall of the small intestine

    Resemble tonsils in structure

    Capture and destroy bacteria in theintestine

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    Mucosa-Associated LymphaticMucosa-Associated Lymphatic

    Tissue (MALT)Tissue (MALT)

    Slide

    Includes:

    Peyers patches

    Tonsils

    Other small accumulations of lymphoidtissue

    Acts as a guard to protect respiratoryand digestive tracts