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Amol Ashok KundeAmol Ashok Kunde 68 RossBrook Model farm Road, CorkMobile: +353-899826285E-Mail: [email protected], [email protected]
Seeking to work in challenging area of neurology Seeking to work in challenging area of neurology development of new computational methods for structure-based design, in docking and lead optimization, and prediction of drug binding kinetics, tumor detection and diagnosis Profile Highlights
Masters in Computational biology with 1.5 years of research experience
Experience in molecular biology techniques, cell based assay systems
Experience in using drug discovery software like Schrodinger, discovery studio, MOE, Sybel
Experience of working Assistant manager for 4 years
Experience in working on Unix based system and obtained certification from Linux academy
Academic programme and Certificate program
Designing a Automated Pipeline for phylogenetic analysis of clinical isolates, Cork , Ireland
Brain Tumor Classification using wavelet and Texture based Neural Network Analysis of Brain Tumor Detection Techniques through Filtering and Segmentation in Matlab
Insilico drug Designing to inhibit entry of Ebola virus through Nieman Pick- C1 Protein, Mumbai Microarray based gene expression profiling on the role of neuropeptide s and neuropeptide s receptor
1 in asthma, Cochin, India Insilico drug designing targeted to COCH gene in LCCI domain of human autoimmune inner ear disease,
Hyderabad, India
Docking Analysis of insulin-like growth factor 1 receptor for identification of role in cancer development , Hyderabad, India
Experience working on design computer aided diagnosis algorithm to increase accuracy of brain tumor detection and classification
Technical Skills And Laboratory Techniques
Computer SkillsOS: Window7/Window8/XP/NT, Unix/Linux/Ubuntu/ RedhatProgramming Language: Phyton, BioPython, Perl, Java, Vb.net, R-programming, MATLABMS-Office suite
Microbiology SkillsAseptic and Sterile Technique, Optical microscopy, Bacterial staining, enumeration and identification of bacteria, use of biological safety cabinets, media and buffer preparation, water sample Analysis by membrane filtration
Biochemistry and Cell Molecular Biology skillsDNA extraction, Plasmid DNA preparation, restriction enzyme digests, PCR, agarose gel electrophoresis, SDS-PAGE, Colonies preparation of bacteria.
Bioinformatics softwares & Tools
Working Knowledge on all major Bioinformatics Software ,Structure database & analysis toolsMolecular Visualization Software: rasmol, pymol, Cn3d, VMD, SwissPdbviewer, MATLAB
Molecular modelling & Docking Software : Modeller, Autodock3, Accelrys Discovery studio 4.1, sybel. Molecular operating Enviortment (MOE), NAMD/VMDGenetic Software : Power marker, Arlequin.Phylogenetic Analysis: RAxML, MrBayes, PhyML, Phylip, ApeBiostatistics software : SPSS 17, R- programming language
Image processing software: ITK –Snap 3.0, signal processing in NMR(SPIN), Imaging in MATLAB
ACADEMIA
Timeline Course DetailsSeptember 2013 –Feb 2015(Honors)
M.Sc in Computational Biology (1 Year, Level-9, Research Masters), CIT, Cork, Ireland.Thesis title: Designing pipeline for phylogenetic analysis of Clinical isolatesKey Modules: Strutural Biology, molecular biology, statistics,python
September 2009 – August 2013First class honours
Graduate in Bioinformatics(4 Years, Level8) ,Padmashree DY Patil University of Biotechnology & Bioinformatics, Navi MumbaiThesis title: Insilico drug designing to inhibit Ebola through Nieman –pick C1 proteinKey Modules: Proteomics, Perl, Java, drug designing, system biology, Matlab, pharmacology, genetic engineering, pharmacology
INDUSTRIAL EXPERIENCE
Worked as Bioinformatics Programmer in INSILICO Labs (6 months full time), Cork, Ireland Worked as bioinformatics Research Associate in Microsatbiolabs(8 months full time), Navi Mumbai Worked as part time tutor in Cork Institute of Technology(3 months), Cork ,Ireland Worked as Assistant Manager in Deep Enterprises (4 years), Mumbai
Research Experience
JOB RESPONSIBILITIES As Bioinformatics Programmer, Nsilico Biotech labs, Cork, Ireland (June 2014-Jan2015)
Responsibility for developing pipeline for Phylogenetics analysis. Extracting sample ,Sequencing, Blast, Extracting 16sRna from provided sequences. Running a sample in Phylogenetics software , Recording time duration, E-scores obtained Predicting results on basis of obtained results ,Commenting on obtain results Reporting results on daily scrum meetings. Designing a code for novel automated pipeline for phylogenetic analysis on ubuntu OS system.
Worked on Simplicity software dream project of Nsilico labs Error handling, Debugging, Evaluating Codes, Updating on daily basis Taking technical care of lab such as maintain computers in labs
JOB RESPONSIBILITIES As Bioinformatics Research Associate, Microsatbiolab, Navi Mumbai ( Jan2013-August2013)
Worked as lab assistant responsibility for maintaining computers, Rectifying technical issue in Computer system.
Designing a novel Insilico drug for inhibition of Ebola Viruses. Extracting a sample of Ebola viruse from join venture company. Sequencing samples, blasting, protein structure predication. Running the sample obtained from company on different drug modelling suite. Worked on Discovery studio 3.1,4..1 2 for making drug analogues . Worked on sybel & Molecular operating Envirotment for designing drug analogues & Scaffold
designing. AMED , Toxicity testing of scaffold designed. Performing Pharmacophore using Ligand Scout software. Performing QSAR Presenting weekly report to the faculty member , Updating work after listening to improvement
made by faculty member.
JOB RESPONSIBILITIES As Assistant Manager Deep Enterprises, Mumbai(Jan2005-August2009)
Full Responsibilty of workshop, mainting a stocks, Products. Daily scrum for noting down progress,issue in work shop. Reporting issue to Manager on daily basis. Preparation of final COA (Certificate of Analysis) before batch release.. Review and Optimize Quality Management System (QMS) in Manufacturing Area. Role to monitor the Quality of Product & maintain the protocols Responsibility for Motivating,training & development of Fresh Candidates Marketing of a Company Product & Plans Optimization of Risk Management System.
Certification
Successful Completion of Training course Linux + LPIC Level 1 Exam 101. Successful Completion of Training course Mastering The Linux Command line Line. Microarray based gene expression profiling on the role of neuropeptide s and neuropeptide s receptor 1
in asthma. Insilico drug designing targeted to COCH gene in LCCI domain of human autoimmune inner ear disease
.
EXTRACURRICULAR ACTIVITIES
Gold Medalist at State Level in “Hindi Competition Examination “ held By Hindi Examination Control
Board Maharastra .
Team Leader as a Volunteer DY PATIL SPORTS CLUB, NAVI MUMBAI.
Captain of Bharti Vidyapeeth Cricket School Team for 3 years.
Won the best scout & guide student of the year
International Conference & Poster Presentation
Collaborative European Research Conference(CERC) October 2013 , CIT, Cork 11th International Conference On Intergration Of Artificial Intellegence(AI) & Operation Research(OR),
UCC, Cork Poster Presentation on “System and Synthetic Approaches for therapeutic intervention against
Leishmania”, National center for cell science,Pune
Activities And Intersest
Travelling across Country(India) explore culture heritage, Food cuisine Hiking and wilderness camping Reading(mythological, hindu Vedas, mysterious collections)
REFERENCES
Name: Dr.Roy SleatorOffice Add : C153 Cork Institute of TechnologyTelephone : (353)-21-4335405Email: [email protected] Title: Head of Biological Department & Co Founder NSilico Life Science, Cork, Ireland
Name: Dr. Helen O sheaOffice Add:C247L Cork Institute of TechnologyTelephone: (353)-21-4335401Email: [email protected] Title: Lecturer & Researcher Investigator, CIT, Ireland
Name: Dr Paul WalshOffice :Melbourne Building CIT Campus, Bishoptown , Cork, IrelandEmail: [email protected] , Tel:353-21-4335572Job Title: Managing Director, NSilico Life Science Ltd
