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JUNE 18–22.2019 PALAZZO DEI CONGRESSI LUGANO (SWITZERLAND) 15 th International Conference on Malignant Lymphoma (ICML) organized by the Foundation for the Institute of Oncology Research (IOR) in cooperation with the American Association for Cancer Research Preliminary Program and Call for Abstracts 15ICML American Association for Cancer Research FINDING CURES TOGETHER®

American Association 15 ICML Preliminary...3 Welcome to 15 –ICML The International Conference on Malignant Lymphoma (ICML) has become, since its first edition in 1981, a must-attend

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Page 1: American Association 15 ICML Preliminary...3 Welcome to 15 –ICML The International Conference on Malignant Lymphoma (ICML) has become, since its first edition in 1981, a must-attend

JUNE 18–22.2019PALAZZO DEI CONGRESSI LUGANO (SWITZERLAND)

15th International Conference on Malignant Lymphoma (ICML)

organized by the Foundation for the Institute of Oncology Research (IOR) in cooperation with the American Association for Cancer Research

Preliminary Programand Call for Abstracts

15–ICMLAmerican Associationfor Cancer ResearchFINDING CURES TOGETHER®

Page 2: American Association 15 ICML Preliminary...3 Welcome to 15 –ICML The International Conference on Malignant Lymphoma (ICML) has become, since its first edition in 1981, a must-attend

www.lymphcon.ch15–ICML

Index 2 Contact details

3 Welcome Organizing Committee and Advisory Board

4 General Information

7 Hotel Accommodation

9 Travel Arrangements

10 Abstract Submission

14 Registration information

17 Provisional Scientific Program

19 Program at a Glance

ICML and Foundation for the IOR President:

Franco Cavalli

Tel: +41 91 811 86 66

[email protected]

ICML Organizing Committee Chairman:

Michele Ghielmini

Tel: +41 91 811 94 10

[email protected]

ICML Secretariat:

Foundation for the Institute of Oncology Research (IOR) via Vela 6 6500 Bellinzona Switzerland

VAT number: CHE-110.407.651 IVA

Cristiana Brentanscientific program and general information [email protected]

Orietta Lugli exhibition, satellite symposia, ancillary [email protected]

Chiara Saporitiregistrations and [email protected] Tel. +41 91 922 05 75

Printed and mailed by courtesy of

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Welcome to 15–ICML

The International Conference on Malignant Lymphoma (ICML) has become, since its first edition in 1981, a must-attend event for the scientific community involved in the study and treatment of lymphoid neoplasms.Its growing success has required, over the years, quite important logistical changes (e.g. broadcast of sessions in overflow rooms, parallel sessions in the nearby university and cinema), but has not changed the main aim of ICML: to permit the presentation of the most recent data - basic, translational and clinical - about lymphoma and the discussion among haematologists, clinical oncologists, radiation oncologists, paediatricians, pathologists and leading researchers from all over the world.Also the Organising Committee’s enthusiasm has not changed and, with the precious help of the many colleagues and friends of the Advisory Board, we have already defined a very interesting frame of the 15-ICML scientific program.The long lasting collaboration with the European School of Oncology (ESO) will continue, with the organisation of the full immersion course on “Leukemia and Lymphoma”, held in Lugano just before our conference, and with the inclusion of ICML in the Certificate of Competence in Lymphoma.Also the cooperation with the American Association for Cancer Research (AACR) continues and grows: we feel honoured to collaborate with AACR friends, who will start a new adventure in holding a meeting on malignant lymphoma in the USA.We invite the submission of high-quality abstracts on all aspects of lymphoid neoplasms, including multiple myeloma and CLL. The very short interval between the deadline of the abstract submission (March 15) and the conference will allow the inclusion of abstracts reporting the most recent results.As always, due to time constraints, only a limited number of abstracts can be selected for proffered papers and, to assure a fair selection, all abstracts will be reviewed by at least 7 international experts.We look forward to welcoming you to Lugano in June 2019.

ORGANIZING COMMITTEE (based in Bellinzona, Switzerland):Francesco BertoniFranco Cavalli – ICML PresidentMichele Ghielmini – ChairmanAlden MocciaBertrand Nadel, Marseilles (France) –

Representative of AACR, American Association for Cancer Research

Fedro Peccatori, Milan (Italy) – Representative of ESO, European School of Oncology

Davide RossiAnastasios StathisGeorg StüssiEmanuele Zucca

ADVISORY BOARD:James O. Armitage, Omaha, NE (USA) –

ChairmanElias Campo, Barcelona (Spain)Bruce D. Cheson, Washington, D.C. (USA)Nicholas Chiorazzi, Manhasset, NY (USA)Wee Joo Chng, Singapore (Singapore)Riccardo Dalla-Favera, New York, NY (USA)Stephan Dirnhofer, Basel (Switzerland)Martin Dreyling, Munich (Germany)

Andreas Engert, Cologne (Germany)Jonathan W. Friedberg, Rochester, NY (USA)Gianluca Gaidano, Novara (Italy)Philippe Gaulard, Créteil (France)Mary K. Gospodarowicz, Toronto (Canada)Peter W.M. Johnson, Southampton (UK)Brad S. Kahl, St. Louis, MO (USA)Ralf Küppers, Essen (Germany)John P. Leonard, New York, NY (USA)T. Andrew Lister, London (UK)Markus G. Manz, Zurich (Switzerland)Ari M. Melnick, New York, NY (USA)Koichi Ohshima, Kurume (Japan)Astrid Pavlovsky, Buenos Aires (Argentina)Leticia Quintanilla-Martinez de Fend, Tübingen

(Germany)S. Vincent Rajkumar, Rochester, MN (USA)Kerry J. Savage, Vancouver BC (Canada)John F. Seymour, Melbourne (Australia)Margaret A. Shipp, Boston, MA (USA)Lena Specht, Copenhagen (Denmark)Catherine Thieblemont, Paris (France)Umberto Vitolo, Turin (Italy)Anas Younes, New York, NY (USA)Wilhelm Wössmann, Hamburg (Germany)Weili Zhao, Shanghai (China)

Franco CavalliICML President

Michele GhielminiChairman of ICML Organizing Committee

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15–ICML

GENERAL INFORMATION

VenueThe 15th International Conference on Malignant Lymphoma will take place in the Lugano Convention Centre, Palazzo dei Congressi.Palazzo dei Congressi is in the centre of the city (it’s a 10-minute walk from the central railway station), but overlooks the beautiful city park (Parco Ciani) and faces the lake of Lugano. Its rooms will host the scientific general sessions and the satellite symposia.Some of “Meet the Professor”, “Focus on…” and other parallel sessions will be held in additional large conference rooms which are 5-minute walk from the main convention centre (Cinema Corso and University). The same halls serve also as overflow rooms for the main sessions, held in Palazzo dei Congressi. For the first time, it will be possible to submit questions to the speaker even from the halls where sessions are broadcasted.Lunches, coffee breaks, poster sessions and the commercial exhibition will take place in the “Marquee Parco Ciani”, a large gazebo built in Parco Ciani, overlooking the lakeshore and connected to Palazzo dei Congressi by a covered walkway.

Participant profileThe 15-ICML will bring more than 3’000 physicians to Lugano from all over the world: haematologists, clinical oncologists, radiation oncologists, paediatricians, pathologists and leading researchers involved in the study and treatment of lymphoid neoplasms.

Demographics from 14-ICML (June 2017):

14 ICML – Participants per country Argentina

Australia

Austria

Belgium

Brazil

Canada

China

Czech Republic

Denmark

France

Germany

Greece

Israel

Italy

Japan

Netherlands

Poland

Portugal

Russia

Spain

Sweden

Switzerland

United Kingdom

United States

Other

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Continuing Medical Education

Application for European CME accreditation (ECMEC) will be made to the European Union of Medical Specialties-European Accreditation Council for Continuing Medical Education (UEMS-EACCME®). European credits are recognised by the American Medical Association (AMA).

Collaboration with the European School of Oncology (ESO)

The 15-ICML program will be part of the third edition of the Certificate of Competence in Lymphoma, a 14 months ECTS program developed by the European School of Oncology (ESO) and academically recognized by the Ulm University. The aim of the Certificate of Competence is to provide a curriculum of studies to advance knowledge and science in the management of lymphoma patients. Further information can be obtained by visiting www.eso.net

Immediately before the 15-ICML, the 2019 Full Immersion Course on Leukaemia and Lymphoma will take place. This is an intensive and interactive course organised in co-operation with ESO.The international faculty will guide participants through the complexity of biology and important clinical problems in leukaemias and lymphomas, offering interactive case-presentations, small group seminars, and ample discussion slots. There will also be opportunities for informal exchange of ideas and views among the participants and the experts.Attendance will be limited to 80 participants and registrations will be received on a first-come/first-served basis.

Date: 15-17 June, 2019Location: Hotel De la Paix, Lugano

Further information can be obtained from the ESO Bellinzona Office([email protected]) or by visiting www.eso.net

14 ICML – Participants per continent

Africa

Asia

Europe

North America

Oceania

South America

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15–ICML

Some of 14-ICML Post-ICML events:

29 September, 201714-ICML Highlights Saudi Society of Blood & Marrow Transplantation (SS-BMT)Jeddah, Saudi Arabia

30 June - 02 July, 2017Best of 14-ICML Lugano Mumbai Hematology Group Mumbai, India

23-25 June, 2017 International Oncology Forum «White Nights» Russian Society of OncohematologistsSt. Petersburg, Russia

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Insurance The ICML Organizing Committee bears no responsibility for untoward events in connection with, before, during and after the congress. Participants are strongly advised to obtain their own personal and travel insurance coverage.

VisaCitizens of some foreign countries will need a visa to enter Switzerland. An overview of visa provisions is available visiting www.lymphcon.ch – individual and group registration information. Please note that only delegates who successfully complete their registration to the conference can receive a Letter of Invitation to submit a visa application.

Italian Delegates Sponsors of Italian delegates who need an AIFA pre-request should address their requests to:

Barbara Mantegazza Aria di Viaggi Srl Congress and Fair Department Via Matteo Bandello, 120123 Milan (Italy)P.I. 02818040152IATA 38220346Tel. +39 02.4818691

Photographs and videos ICML reserves the right to photograph and videotape the congress and participants and to use such photographs and videos in any internal and external communication referring to ICML (website, Preliminary Program and Call for Abstracts or other publications). By registering, consent to such uses is assumed.

HOTEL ACCOMMODATION

Booking of hotel accommodation should be made contacting:

Amiconi Consulting SAVia al Forte 10CH-6900 Lugano, Switzerland Tel: +41 (0)91 921 38 12Fax: +41 (0)91 921 38 13 e-mail: [email protected]

Due to heavy room demand, early booking is advisable in order to arrange proper accommodation. All efforts will be made to assign hotel rooms according to the participants’ choice. However, should this not be possible, alternative category and/or location will be provided.

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oneworld benefits are available only to passengers on scheduled flights that are both marketed and operated by a oneworld member airline (marketed means that there must be a oneworld member airline’s flight number on your ticket). For information on oneworld, visit www.oneworld.com. American Airlines, British Airways, Cathay Pacific, Finnair, Iberia, Japan Airlines, LATAM Airlines, Malaysia Airlines, Qantas, Qatar Airways, Royal Jordanian,S7 Airlines, SriLankan Airlines and oneworld are trademarks of their respective companies. LATAM Airlines (Paraguay) is currently not a part of oneworld.

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TRAVEL ARRANGEMENTSLugano is situated in Ticino, the italian-speaking part of Switzerland, close to the Italian border. The city is well connected, both with regards to motorway as well as railway networks, and it has several airports in the surroundings.

Lugano-Agno (LUG) airport is served by domestic flights departing from Geneva (GVA) and Zurich (ZRH), the major Swiss international airport. The train connection from Zurich airport (about 220 km from Lugano) is an efficient and pleasant option: with the New Rail Link through the Alps, opened in December 2016, the journey - through some of Switzerland’s most beautiful landscapes and views – takes about 2 hours.Please visit http://www.sbb.ch for prices, timetables and online bookings.

From June 2018 Lugano is also connected by train to Milan-Malpensa (MXP), the closest international airport (about 60 km from Lugano, in Italy). The train trip takes 1 hour and 45 minutes.Please visit http://www.tilo.ch for prices and timetables.Different bus connections (Giosy Tours-Malpensa Express CH, Lugano Services, Jetbus) are also available and the shuttle trip takes about 1 hour.

Other options are Milan-Linate (LIN) and Bergamo-Orio al Serio (BGY) airports, both in Italy, connected to Milan by bus and then to Lugano by train.

Private transfer servicesAmiconi Consulting SA can be contacted to arrange private transfer services from and to the airports (Milan-Linate, Milan-Malpensa, Bergamo-Orio al Serio and Lugano-Agno) and in the city of Lugano and its surroundings, for both individuals and groups.

Official CarrierFor the first time, 15-ICML will partner with the oneworld airline alliance to offer to participants discounts on flights and many other benefits for their air travel to the conference, as follows:

• Travel up to seven days before and seven days after the event.

• Flights available from all oneworld member airlines and affiliates.

• A user-friendly booking tool showing the most convenient flight options.

• 24-hour support via email or phone.

• Rewards and tier status points on eligible oneworld flights.

• Frequent flyer privileges including access to some 650 premium airport lounges worldwide, fast track at security lanes in selected airports and extra baggage allowance.

• Seamless connections and quality service on oneworld member airlines.

The online booking tool is available at  www.oneworld.com/events  as of September 2018.To access the online booking tool and take advantage of the offer, enter event code OW44B17.

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ABSTRACT SUBMISSION(deadline: Friday, March 15, 2019, 17:59 CET)

Abstracts for oral presentations (general sessions and “Focus on…” sessions) and poster presentation must be submitted online from Saturday, December 1, 2018 until Friday, March 15, 2019, 17:59 CET via www.lymphcon.ch.

Abstracts can be related to all aspects of biology and treatment of lymphoid neoplasms.

The submission of an abstract does not constitute registration for ICML. Abstract presenters must register to attend the meeting. Simultaneous abstract submission and registration for the congress are highly recommended.

Notification regarding abstract evaluation results (acceptance for oral or poster presentation, inclusion in the Abstract Book or rejection) will be sent to the first author/presenter by Friday, May 3, 2019.Early registration fee applies for presenters of abstracts selected for oral presentation.

Encore abstractsSubmission of original scientific material unpublished at the time of the abstract submission deadline is encouraged.

Encore abstracts are accepted only if already submitted to and/or presented at:

– regional or national meetings

– ASCO 2019 and EHA 2019, the large international meetings which are or-ganized in the same period as ICML (May – July) by the American Society of Clinical Oncology (ASCO) and the European Hematology Association (EHA).

Except for the above mentioned situations, during submission, first authors are asked to certify that the submitted abstract has neither been nor will be previously published before release of 15-ICML Abstract Book (Wednesday, June 12, 2019).Updated  analyses must substantially differ from previously published manuscripts. 

Ongoing trials abstractsAbstracts describing trials in progress can be submitted, provided that:

– patient enrolment has already started

– new patient accrual is still possible

Text of ongoing trials abstracts is expected to include only the 2 following sections: Introduction and Methods.

These abstracts will be evaluated for oral presentation (in a general session or a “Focus on Ongoing trials” session), poster presentation or inclusion in the Abstract Book. The presentation format will be decided by the Organizing Committee on the basis of the evaluation results and the scientific program structure.

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Late-Breaking Abstracts(deadline: Wednesday, April 24, 2019, 17:59 CEST)

Late-Breaking Abstracts may be submitted for studies that will have conclusive data available after the regular abstract submission deadline.

A preliminary abstract (placeholder abstract) must be submitted online by the regular abstract deadline (March 15, 2019, 17:59 CET).

A covering letter must be sent to ICML Secretariat ([email protected]), indicating the data expected to be available by the late-breaking abstract deadline.Only abstracts anticipating very high quality research findings will be accepted.

A member of ICML Organizing Committee will contact the first author in order to discuss the study in detail.

No Late-Breaking Abstract will be considered without the submission of the placeholder abstract and the covering letter.

First author responsabilities The submission of an abstract constitutes a formal commitment by the first author to present the abstract (if accepted) orally or as a poster.The first author serves as presenter and primary contact for all correspondence regarding the abstract.

Upon submission of an abstract, the first author/presenter is responsible for the following:

• ensuring that all authors have read the abstract and agreed to be co-authors;

• forwarding all correspondence regarding the abstract to all co-authors;

• releasing abstract copyright to John Wiley and Sons, Inc. (publisher of 15-ICML Abstract Book as supplement to “Hematological Oncology”), for inclusion in ICML abstract book and its licensee publications with educational purposes;

• giving permission to record his/her presentation during 15-ICML for multimedia coverage, release to attendees and licensees for educational purposes;

• disclosing any conflict of interest, declaring the name of the company (s)he maintains a “relevant financial relationship”* with. Unless otherwise indicated, it is implied that there are no conflicts of interests pertinent to the abstract;

*“Relevant financial relationships” are intended those from which the author or any individual with whom he/she directly shares income has received or may receive financial benefit within the past 24 months. The relationships to declare are: employment or leadership position in a company – consultant or advisory role - stock ownership – honoraria – research funding – other remuneration.

• releasing copyright and providing conflict-of-interest disclosure on behalf of co-authors;

• certifying that the same abstract has neither been nor will be previously published before 15-ICML, except for regional or national meetings, ASCO 2019 and EHA 2019.

Furthermore, the first author/presenter certifies that the abstract will not be included as such in the scientific material produced in connection with any satellite symposium held during 15-ICML.

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Abstract submission informationDuring the online abstract submission, the following information will be required:

– First author/presenter complete contact details (first and middle name, surname, department, affiliation, mailing address, city and country, telephone number, e-mail address), for future correspondence and notification on the abstract evaluation outcome;

– Co-authors’ first and middle name initials, surname, department, affiliation, city and country.

– Preference of presentation: Oral presentation (including “Focus on...” sessions) or Poster presentation. The Organizing Committee reserves the right to conclusively decide the presentation format, on the basis of the evaluation results and the scientific program structure.

– Ongoing trials abstract eligibility (please check the pertinent paragraph for conditions).

– Option of withdrawal of the abstract in case of selection for publication only in the Abstract Book (i.e.: if the abstract is not selected for oral or poster presentation).

NB: Changes of the option of withdrawal are not possible after the submission deadline.

– Application for a travel award, in case the abstract is selected for oral or poster presentation. The applicant must be first author/presenter of the abstract and aged 35 years or younger.

– Keywords (minimum 1 – maximum 3), to be selected from the list available online.

– Acceptance of abstract submission policy and regulations including first author/presenter responsibilities and in particular:

1. release of copyright and permission to multimedia recording of presentation for educational purposes, also on behalf of the co-authors;

2. disclosure of conflict of interest, also on behalf of the co-authors;

3. no prior publication of the same abstract, except for regional and national meetings, ASCO 2019 and EHA 2019;

4. no inclusion of the same abstract in the scientific material produced in connection with any satellite symposium.

5. withdrawal policy: abstracts selected for oral or poster presentation must be presented, unless indicated during the submission. Abstract withdrawal requests received after the deadline can not be accepted. If the presenting author can not present the abstract, (s)he should nominate a co-author and inform ICML Secretariat ([email protected]) of the replacement as soon as possible.

Guidelines for abstract preparation • Abstracts must not be longer than 2’500 characters (text and table included;

title, authors’ list and spaces not included).

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13• The title must not exceed 150 characters (spaces not included).

Names of cooperative study groups should appear in the title, as they can not be included in the authors’ list.

• The number of listed co-authors must be limited to thirty-five (35). First author/presenter name will be underlined. All authors will be listed

with first and middle name initials, surname, department, affiliation, city and country.

Please note that, in order for affiliations to be grouped properly, the exact same information for affiliation, department, city, and country fields must be entered.

• All abstracts (except for ongoing trials) should include the following 4 sections: Introduction, Methods, Results, Conclusions.

• Only one brief and simple data table is permitted in the text of the abstracts. The table counts for 350 characters.

• One image can be submitted and it’s not included in the character count. Only JPG, GIF or PNG file can be uploaded.

The image options must be: Width and Height (in px): 500; Size (in KB): 1000; DPI: 300.

Images not adhering to these options and images with no readable texts will be removed from the abstract book without further recourse to the first author.

• Compounds should be mentioned with the generic name in lower case. Commercial names may not be used in the title of the abstract. Commercial names are admitted in the text, in brackets and with the ® symbol, following the generic name, i.e. ‘generic (Commercial®)’.

Educational Book and Abstract Book All selected abstracts will be included in the Abstract Book, supplement to “Hematological Oncology” (John Wiley and Sons, Inc.), published online on the pertinent Wiley Online Library website as of Wednesday, June 12, 2019. Prior to this date, submitted abstracts are treated as confidential by ICML (Organizing Committee, Advisory Board, 15-ICML reviewers), first author, co-authors, research sponsors.

Summaries of the Educational sessions will be included in the Educational Book distributed to attendees on site and also available online.

Travel Grants and Merit AwardBased on funding availability, a limited number of travel grants, sponsored by the Swiss Cancer League and possibly by other contributors, will be provided to young investigators (less than

35 years), whose abstract has been accepted for oral or poster presentation. The selection will be made on the basis of the abstract evaluation results. The travel grant, meant to defray travel expenses for attending ICML, can be applied for by eligible first authors during the abstract submission.

Based on funding availability, a “merit award” will be given to the young investigator author of the highest-scoring abstract and selected for a travel grant. The recipient will receive complimentary registration, a monetary support to attend 15-ICML and will be recognized for his/her scientific merit during the conference.

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REGISTRATION INFORMATION

Due to space restrictions, attendance is limited and registration is available on a first-come, first-served basis. Well in advance registration is encouraged. Registrations will be closed upon reaching the maximum allowed number of paid registrations. In this case a waiting list will be opened and further registrations from the list will be confirmed in case of cancellations.

What the full registration does includeThe full registration fee covers access to the scientific sessions, poster session and Exhibition area, participation in the Satellite Symposia (unless otherwise indicated by the Symposia’s organizers), a copy of the 15-ICML Educational Book, three lunches, refreshment breaks and the Farewell Aperitif on Friday, June 21, 2019.15-ICML Abstract Book, supplement to «Hematological Oncology» (John WIley and Sons, Inc.) will be available online on the Wiley Online Library website as of Wednesday, June 12, 2019.

All delegates staying in a hotel, hostel or camping in the Ticino Region and subject to the full tourist tax are entitled to the Ticino Ticket, a pass valid for the duration of their stay.Ticino Ticket holders can use free of charge the regular public transportation system (which includes trains, buses and postal buses of the “Arcobaleno Community”) and receive a discount to cable car and funicular companies and other tourist attractions.Details are available at: https://www.ticino.ch/en/ticket.html

Furthermore, a private bus service, running at scheduled times from and to hotels, is granted to delegates staying in Italy or in hotels not reached by public transportation and having booked through 15-ICML appointed agency, Amiconi Consulting SA. Detailed timetable will be available at www.lymphcon.ch in the spring 2019.

Registration feeThe registration fees are based on the following deadline schedule:

Early Registration CHF 1’000.– until February 28, 2019 if places are still available

Late Registration CHF 1’400.– from March 1, until June 11, 2019 if places are still available

Payment informationPayment can be processed by credit card (Visa, Mastercard and American Express), through ICML online payment system, or by bank transfer.

The wire transfer, with no costs to the beneficiary, should be made to:

Account holder: Fondazione per l’Istituto Oncologico di Ricerca (IOR)Account name: ICMLAccount number: 336 9742 C001CBank name: Banca dello Stato del Canton Ticino

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15Bank address: via Pioda 7, 6900 Lugano, SwitzerlandIBAN code: CH47 0076 4336 9742 C001 CSWIFT code: BSCTCH22LUG Clearing number: 00764

The name of the participant or the group registration should be clearly stated on the bank transfer.

INDIVIDUAL REGISTRATION

Application to participate in the 15-ICML can be made online at www.lymphcon.ch and registration is confirmed when full payment is settled, by credit card or by bank transfer.

Confirmation of registration and invoice (if pertinent fields are filled in) will be sent within 5 working days after the payment is processed.

ICML Secretariat may revoke tentative registrations if payment is not settled within 10 days after submission of online registration.

The registration form can be obtained at www.lymphcon or contacting the ICML Secretariat.

Cancellation of individual registrationIndividual registration fee is refundable (minus 20% administration charges) if email notification is received by ICML Secretariat by Thursday, May 24, 2019. Reimbursements will be processed after the congress.

Individual registration name changeName changes, with no extra fees, will be accepted by email notification by Thursday, May 24, 2019.After this deadline, a penalty fee of CHF 200.– will be charged for each name change.

Invitation LetterDelegates who successfully complete their registration for the conference can receive an Invitation Letter to submit a visa application. An Invitation Letter can be requested by providing needed data in the online registration form.The invitation letter does not commit ICML to any financial obligations whatsoever.

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GROUP REGISTRATION (minimum: 10 participants)

Summary of the deadlines for Group Registration

Payment of early fees CHF 1’000.– until February 28, 2019 (no-name registrations) if places are still available

Payment of late fees CHF 1’400.– from March 1 until June 11, 2019 if places are still available

Participants list by May 24, 2019 (names and addresses)

Collection of the material from June 17, 2019

Group administrators should complete the group registration form available online at www.lymphcon.ch/Registrations/GroupRegistration, specifying the number of no-name registrations, group name, preferred method of payment (credit card or bank transfer) and housing information (booking source, booked rooms number and hotel name should be provided).

Once the payment is settled, the group administrator will be able to include the required personal data of each participant in the conference database, using the group registration username and password.Group administrators must provide complete information on each participant (including the full address of the institute and the personal e-mail address) by Thursday, May 24, 2019.

Group registration name changesName changes, at no extra fee, are allowed up until Thursday, May 24, 2019. Name changes must be processed online accessing to the group record through the log in credentials.After this deadline, a penalty fee of CHF 200.– will be charged for each name change and for each name not yet provided.

Cancellation of group registrationGroup registration fees are refundable (minus 20% administration charges) if email notification is received by ICML Secretariat by Monday, February 11, 2019. After this deadline, group registration fees will be not refundable. Reimbursements will be processed after the congress.

Invitation letterGroup administrators can ask for delegates’ invitation letters sending an email to [email protected] and providing delegates’ passport details.Invitation letters can be issued only for delegates who successfully complete their registration for the conference.The invitation letter does not commit ICML to any financial obligations whatsoever.

Congress materials for groups will be available for pick up at preassigned times on Monday, June 17, 2019, at the Registration Desk in Palazzo dei Congressi main hall.Please ask for an appointment sending an e-mail to [email protected].

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17

PROVISIONAL SCIENTIFIC PROGRAM

Based on the abstracts received and accepted for oral presentation, general sessions will be devoted to either specific subtypes of lymphoid neoplasia (e.g. mantle cell lymphomas, follicular lymphomas, T-cell lymphomas, etc), or to the presentation of laboratory and clinical research data grouped around a biologic topic (for example, microenvironment, signalling pathway, surface antigens).

“Focus on...” are parallel oral sessions highlighting abstracts of scientific value but not selected for oral presentation during the general sessions. These sessions will be run in parallel and each will be focused on a particular topic. The one-hour sessions will consist of six presentations of 10 minutes each, including discussion.

Key Note Lectures:

– Henry Kaplan Memorial Lecture and San Salvatore Foundation Award Title to be announced

Carl H. June, Philadelphia, PA (USA)

– Gianni Bonadonna Memorial Lecture (supported by American Association for Cancer Research)

“Precision Epigenetic Therapy for B-cell lymphomas” Ari M. Melnick, New York, NY (USA)

– John Ultmann Memorial Lecture (supported by European School of Oncology) “Thirty years of T-cell lymphomas” Philippe Gaulard, Créteil (France)

Educational symposia (parallel sessions):

a. “Treating Hodgkin Lymphoma in the new millennium” New first lines: Peter W.M. Johnson, Southampton (UK) R/R: Ann S. LaCasce, Boston, MA (USA) Elderly patients: Andreas Engert, Cologne (Germany) - Chairmanb. “New drugs for NHL: beyond chemotherapy” Immunotherapies: Renier J. Brentjens, New York, NY (USA) New drugs for old targets: Gilles A. Salles, Lyon (France) - Chairman New drugs for new targets: Anas Younes, New York, NY (USA)

Meet the Professor sessions:

1. Multiple myeloma: every year a new standard? – S. Vincent Rajkumar, Rochester, MN (USA)

2. How to approach CLL in clinical practice – Michael Hallek, Cologne (Germany)

3. Managing the toxicities of CAR T-cell therapy – Sattva S. Neelapu, Houston, TX (USA)

4. What we should know about NK/T-cell lymphomas – Weili Zhao, Shanghai (China)

5. Cutaneous lymphomas – Werner Kempf, Zurich (Switzerland) 6. PCNSL, a curable disease – Tracy T. Batchelor, Boston, MA (USA) 7. Breast implant associated ALCL and other rare T-cell lymphomas –

Laurence de Leval, Lausanne (CH) 8. Liquid biopsy: a clinical tool, already? – Ash A. Alizadeh, Stanford, CA (USA) 9. Double Hit lymphoma, so what? – Andrew Davies, Southampton (UK)10. The modern approach to mantle cell lymphoma – Simon Rule, Plymouth

(UK)11. Hairy Cell leukemia, new treatment options – Brunangelo Falini, Perugia

(Italy)

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15–ICML

12. Rare B cell lymphomas in children and adolescents – Wilhelm Wössmann, Hamburg (Germany) and Leticia Quintanilla-Martinez de Fend, Tübingen (Germany)

Clinical case discussion sessions have presenters of outstanding centers addressing cases which are not trivial nor very rare, but rather situations commonly encountered where the solution remains controversial. The format is a sort of Europe vs. USA debate: we had Lysa (France) vs Mayo Clinic in 2013, FIL (Italy) vs New York centers in 2015 and German vs Californian institutes in 2017. In 2019 we will have the following Spanish vs Texan experts presenting cases and discussing the treatment options:

1. HL: Ana Maria Sureda Balari vs Hun Ju Lee 2. FL/Indolent Lymphoma: Mariano Provencio Pulla vs Loretta J. Nastoupil 3. PTCL: Alejandro Martín vs Nathan H. Fowler 4. DLBCL: Eva Giné Soca vs Jason R. Westin 5. CLL: Julio Delgado vs Philip A. Thompson 6. Clinico-pathological difficult cases: Armando Lopez-Guillermo vs Fredrick

B. Hagemeister 7. Radiotherapy in lymphoma: TBD vs Bouthaina S. Dabaja

Ongoing trials presentation: this session will comprise abstracts describing trials in progress. Conditions for being selected for presentation at this session are:

– already started enrolment, – still possible accrual of new patients.

The session should not be regarded as an advertisement for new drugs. Trials which are close to completion (i.e. not available for other possible participants) and closed trials will not be considered for presentation.

15-ICML Highlights“Take home messages” Speaker to be announced

Special AACR-ICML sessionAfter the 2015 and 2017 positive and fruitful experiences, AACR and ICML will organize once again in 2019 a special joint session. The session will be devoted to the role of pre-clinical models as bridges to early clinical phases.

Special sessions devoted to radiotherapy, organized in collaboration with ILROG (International Lymphoma Radiation Oncology Group): two satellite workshops open to all 15-ICML attendees will take place.

Details will be available closer to the event at www.lymphcon.ch.

IBSA Foundation for Scientific Research - Special ForumAs in 2017, when the event “Basic mechanisms of cancer immunotherapy” took place, ICML participants will again have the possibility to join the IBSA Foundation Special Forum. The forum will be organised  in the University Auditorium and the program will be defined in collaboration with the Foundation for the Institute of Oncology Research (IOR).

IV International Workshop on Canine LymphomaThis well-attended meeting fosters interdisciplinary contacts between researchers studying lymphoma in canine and other species. The 2019 edition will comprise an invited plenary lecture on a cutting-edge topic, an update on the activities of the European Canine Lymphoma Network, a round table on state-of-the-art on canine multicentric lymphoma staging, and, for the first time, a session with free oral research presentations.

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19

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15–ICML

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21

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sess

ion

(16:

45-1

7:45

)“F

ocus

on…

” se

ssio

n (1

6:45

-17:

45)

“Foc

us o

n…”

sess

ion

(16:

45-1

7:45

)17

:00

17:1

5

17:3

0

17:4

5

18:0

0

18:1

5

18:3

0

CELG

ENE

CORP

ORAT

ION

sate

llite

sym

posi

um

(18:

30-2

0:00

)

SERV

IER

sate

llite

sym

posi

um

(18:

30-2

0:00

)

CELL

TRIO

N He

alth

care

sate

llite

sym

posi

um

(18:

30-2

0:00

)

AVAI

LABL

E sa

telli

te s

ympo

sium

(1

8:30

-20:

00)

18:4

5

19:0

0

19:1

5

19:3

0

19:4

5

20:0

0

Plea

se n

ote

that

this

draf

t pro

gram

was

prin

ted

and

circ

ulat

ed in

May

201

8. F

inal

pro

gram

will

diff

er in

som

e de

tails

. In

parti

cula

r, th

e co

nten

t of t

he g

ener

al s

essio

ns a

nd “

Focu

s on

…”

sess

ions

will

be

defin

ed o

n th

e ba

sis o

f the

abs

tract

eva

luat

ion.

Page 22: American Association 15 ICML Preliminary...3 Welcome to 15 –ICML The International Conference on Malignant Lymphoma (ICML) has become, since its first edition in 1981, a must-attend

www.lymphcon.ch

22

15–ICML

FRID

AY, J

UNE

21Ro

om A

Pala

zzo

dei C

ongr

essi

Room

BPa

lazz

o de

i Con

gres

siM

arqu

eePa

rco

Cian

iCi

nem

a Co

rso

Audi

toriu

mUn

iver

sity

Aula

Mag

naUn

iver

sity

7:15

7:30

7:45

EXHI

BITI

ON A

REA

and

POST

ER S

ESSI

ON

(9:0

0-18

:30)

8:00

Mee

t the

Pro

fess

or (8

:00-

8:45

) M

eet t

he P

rofe

ssor

(8:0

0-8:

45)

Mee

t the

Pro

fess

or (8

:00-

8:45

) M

eet t

he P

rofe

ssor

(8:0

0-8:

45)

Mee

t the

Pro

fess

or (8

:00-

8:45

) 8:

15

8:30

8:45

9:00

Clin

ical

cas

e di

scus

sion

(0

9:00

-10:

30)

SESS

ION

6:

Lym

phom

a Ge

nom

ics

(9:0

0-10

:30)

Ro

om B

- M

arqu

ee

broa

dcas

ting

of

SESS

ION

6 (9

:00-

10:3

0)

Clin

ical

cas

e di

scus

sion

(0

9:00

-10:

30)

Clin

ical

cas

e di

scus

sion

(0

9:00

-10:

30)

9:15

9:30

9:45

10:0

0

10:1

5

10:3

0CO

FFEE

(10:

30-1

1:00

)10

:45

11:0

0SE

SSIO

N 7:

Ad

vanc

es in

CLL

(11:

00-1

2:00

) R

oom

A -

B - M

arqu

ee -

Cine

ma

Cors

o - A

ula

Mag

na

broa

dcas

ting

of

SESS

ION

7 br

oadc

astin

g of

SE

SSIO

N 7

broa

dcas

ting

of

SESS

ION

7 11

:15

11:3

0

11:4

5

12:0

0LU

NCH

TIM

E an

d PO

STER

VIE

WIN

G(1

2:00

-13:

00)

12:1

5

12:3

0

12:4

5

13:0

0JO

HN U

LTM

ANN

MEM

ORIA

L LE

CTUR

E (1

3:00

-13:

45)

Room

A -

B - M

arqu

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Cine

ma

Cors

o - A

ula

Mag

na

broa

dcas

ting

ofJo

hn U

ltman

n Le

ctur

e br

oadc

astin

g of

Jo

hn U

ltman

n Le

ctur

e br

oadc

astin

g of

Jo

hn U

ltman

n Le

ctur

e 13

:15

13:3

0

13:4

5

SESS

ION

8:

Folli

cula

r Lym

phom

a (1

3:50

-15:

35)

Room

A -

B - M

arqu

ee -

Cine

ma

Cors

o - A

ula

Mag

na

broa

dcas

ting

of

SESS

ION

8 br

oadc

astin

g of

SE

SSIO

N 8

IBSA

FOU

NDAT

ION

SPEC

IAL

FORU

M

open

to a

ll 15

-ICM

L pa

rtici

pant

stim

e TB

D

broa

dcas

ting

of

SESS

ION

8

14:0

0

14:1

5

14:3

0

14:4

5

15:0

0

15:1

5

15:3

0 C

OFFE

E (1

5:35

-16:

05)

COF

FEE

(15:

35-1

6:05

)15

:45

16:0

0

SESS

ION

9:

Aggr

essi

ve Ly

mph

oma

(16:

05-1

7:35

) Ro

om A

- B

- Mar

quee

- Ci

nem

a Co

rso

- Aul

a M

agna

broa

dcas

ting

of

SESS

ION

9 br

oadc

astin

g of

SE

SSIO

N 9

broa

dcas

ting

of

SESS

ION

9

16:1

5

16:3

0

16:4

5

17:0

0

17:1

5

17:3

0

Fare

well

Aper

itif

(17:

35-1

8:30

)

17:4

5

18:0

0

18:1

5

18:3

0 IO

SI -

THE

BIG

DEBA

TE(1

8:30

-19:

30)

supp

orte

d by

GIL

EAD

SCIE

NCES

Ltd

.AV

AILA

BLE

sate

llite

sym

posi

um

(18:

30-2

0:00

)

18:4

5

19:0

0

19:1

5

19:3

0

19:4

5

20:0

0

Plea

se n

ote

that

this

draf

t pro

gram

was

prin

ted

and

circ

ulat

ed in

May

201

8. F

inal

pro

gram

will

diff

er in

som

e de

tails

. In

parti

cula

r, th

e co

nten

t of t

he g

ener

al s

essio

ns a

nd “

Focu

s on

…”

sess

ions

will

be

defin

ed o

n th

e ba

sis o

f the

abs

tract

eva

luat

ion.

Page 23: American Association 15 ICML Preliminary...3 Welcome to 15 –ICML The International Conference on Malignant Lymphoma (ICML) has become, since its first edition in 1981, a must-attend

www.lymphcon.ch 15–ICML

23

SATU

RDAY

, JUN

E 22

Room

A

Pala

zzo

dei C

ongr

essi

Room

BPa

lazz

o de

i Con

gres

siAu

dito

rium

Univ

ersi

ty7:

15

7:30

7:45

8:00

8:15

8:30

SESS

ION

10:

Imm

unot

hera

pies

(0

8:30

-10:

00)

SESS

ION

11:

Man

tle C

ell L

ymph

oma

(08:

30-1

0:00

)

ESO

(Eur

opea

n Sc

hool

of O

ncol

ogy)

ES

MIT

(E

urop

ean

Scho

ol o

f Mul

timod

ality

Im

agin

g &

Ther

apy)

“P

ET IN

LYM

PHOM

A”

(8:3

0-10

:30)

8:45

9:00

9:15

9:30

9:45

10:0

0

10:1

5SE

SSIO

N 12

: Mar

gina

l Zon

e Ly

mph

oma

Room

A -

B (1

0:15

-11:

15)

10:3

0

10:4

5

11:0

0

11:1

515

-ICM

L HI

GHLI

GHTS

“T

ake

Hom

e M

essa

ges”

(1

1:20

-11:

45)

11:3

0

11:4

5

12:0

0CL

OSUR

E AN

D FA

REW

ELL

(11:

50-1

2:00

)12

:15

12:3

0

12:4

5

13:0

0

13:1

5

13:3

0

IV IN

TERN

ATIO

NAL

WOR

KSHO

P ON

CAN

INE

LYM

PHOM

A op

en to

all

15-IC

ML

atte

ndee

s (1

3:30

-18:

15)

13:4

5

14:0

0

14:1

5

14:3

0

14:4

5

15:0

0

15:1

5

15:3

0

15:4

5

16:0

0

16:1

5

16:3

0

16:4

5

17:0

0

17:1

5

17:3

0

17:4

5

18:0

0

18:1

5

Plea

se n

ote

that

thi

s dr

aft

prog

ram

was

prin

ted

and

circ

ulat

ed i

n M

ay 2

018.

Fin

al p

rogr

am w

ill d

iffer

in

som

e de

tails

. In

par

ticul

ar, t

he c

onte

nt o

f the

gen

eral

ses

sions

and

“Fo

cus

on…

” se

ssio

ns w

ill b

e de

fined

on

the

basis

of t

he a

bstra

ct e

valu

atio

n.

©

Mark SaggiaEvent Coordinator - Structural consultant +41 78 706 30 12 [email protected]

EVENTMORE SAVia S. Gottardo 18DCH - 6532 Castionephone: +41 91 863 20 93fax: +41 91 850 10 61

Mark SaggiaEvent Coordinator - Structural consultant +41 78 706 30 12 [email protected]

EVENTMORE SAVia S. Gottardo 18DCH - 6532 Castionephone: +41 91 863 20 93fax: +41 91 850 10 61

Page 24: American Association 15 ICML Preliminary...3 Welcome to 15 –ICML The International Conference on Malignant Lymphoma (ICML) has become, since its first edition in 1981, a must-attend