AKOTTAKOTT NESULINENESULINE

FROM THE FROM THE SPLENDOURSPLENDOUR

OF THE OF THE ANCIENT EGYPTANCIENT EGYPTTHE SECRETS OF ATHE SECRETS OF A

TIMELESS TIMELESS BEAUTYBEAUTY

NESULINENESULINE is an Egyptian-inspired line of Minerals, Botanicals and sophisticated Active Ingredients

targeted to Elite Cosmetics.

AkottAkott has taken inspiration from the ANCIENT EGYPTIANS’ PIONEERING BEAUTY PERCEPTION,

creating the concept of ANCIENT BEAUTY IN HIGH DEFINITIONANCIENT BEAUTY IN HIGH DEFINITION

““Millenary tradition conjugated to Modern science!Millenary tradition conjugated to Modern science!””

THE ANCIENT EGYPTIAN SCIENTISTS The Egyptians made extensive use of mineral powders and synthesized

other compounds using relatively sophisticated chemical techniques. They were fond of eye and face coloration of white, green and black.

Ultrafine powders, obtained from precious stonesprecious stones, that bestow a luxury

touch, for Superior cosmetics…

®®AKOSHINEAKOSHINE LINELINE

®AKOBIOLAKOBIOL LINELINE

ANCIENT EGYPTIAN GARDENS Gardens were very popular among ancient Egyptians. Houses,

palaces, temples nearly always have a garden next to the building. Gardens also provided food, including fruit, vegetables and wine.

Rare essences and botanicals - anciently employed to manufacture perfumes, massage oils, beauty masks -

revisited according to the modern notion of green, green, naturenature--friendlyfriendly cosmetics…

®AKOACTIVE HORUSHORUSFROM THE VANITY

OF THE PHARAOHTHE SECRET OF

THE MAGICAL LIPOACTIVEFOR A DIVINE WELL-BEING

AKOACTIVE HORUSHORUSis inspired to the fascinating Egyptian myth of the Pharaoh/God.

AKOACTIVE HORUS , THE MAGIC PHARAOHS “LIPOACTIVE”, an ingredient with NOURISHING, MOISTURIZING, SOOTHING AND

REPAIRING PROPERTIES, devised to pamper sensitive skin, the way the Pharaohs took care of their own divine appearance.

Akott Researchers reinvented tradition by couplingthe curative power of Nigella sativa seeds +

the emolliency of Moringa seed oil

CHARACTERISTICS

INCI NAME (CTFA): Caprylic/capric triglyceride, Moringa oleiferaseed oil, Nigella sativa seed extract.

PHYTOCHEMICAL ACTIVE COMPONENTSFatty acids:OMEGA-6 = Linoleic acid, Eicosadienoic acid OMEGA-7 = Palmitoleic acidOMEGA-9 = Oleic acid, Erucic acidPalmitic acidStearic acidGadoleic acidArachidic acidPhytosterols:gamma-SitosterolStigmasterolOther actives:ThymoquinoneD-limonene

BOTANICAL FEATURESNIGELLA SATIVA SEED: anti-inflammatory, anti-oxidant, contains phytosterols, vitamins and precious oligoelements.MORINGA OIL: rich in unsaturated fatty acid, extremely stable, emollient, nourishing.

APPLICATIONS

AKOACTIVE HORUSHORUS is indicated in case of alterations of the skin barrier (dehydration, dermatitis, hypersensitivity) as well as for the cosmetic treatment of skin inflammatory symptoms and skin aging.AKOACTIVE HORUSHORUS can be employed in a wide range of applications such as: anti-age products, sun care, hair care, post-depilatory creams, baby products and sensitive skin products.

RECOMMENDED DOSAGE : 2 – 10%

®AKOACTIVEAKOACTIVE NILE LILYNILE LILY

FROM CLEOPATRA,A “WAY AHEAD OF HER

TIME” WOMAN,THE SECRETS OF THE

ACTIVE FOR A

TIMELESSTIMELESS BEAUTY

AKOACTIVE NILE LILYNILE LILY is a POWERFUL ANTI-AGEING LIPOACTIVE

with a MULTIFUNCTIONAL REJUVENATING EFFECT.

Akott Researchers devised a novel synergy: Zantedeschia elliottiana flower extract +

Bakuchiol, purified Babchi seed

Cleopatra’s splendid palace was surrounded by magnificent gardens. Among the

hundreds of species, a dazzling yellow flower with golden spathes shone like gold:

the Nile Lilythe Nile Lily (Zantedeschia elliottiana)

CHARACTERISTICSINCI (CTFA) Name: Caprylic/capric triglyceride, Zantedeschia elliottiana

flower extract, Bakuchiol.

PHYTOCHEMICAL ACTIVE COMPONENTSTriterpenesTriterpenes (Squalene): it has free-radical scavenging properties

and it helps the recovery of skin barrier integrity and functionality and prevents skin TEWL.PhytosterolsPhytosterols (gamma-Sitosterol, Campesterol, Stigmasterol,

Cycloleucalenol): prevent skin ageing by stimulating collagen and extracellular matrix fibers synthesis in the dermis. It improves skin metabolism and reduces inflammation. Fatty acids Fatty acids (Linoleic acid (Omega-6), Oleic acid (Omega-9), Palmitic

acid, Stearic acid): help the stratum corneum to restore its barrier function and also provide antioxidant and anti-inflammation properties; in addition linoleic acid is known to enhance actives penetration in the skin.BakuchiolBakuchiol: a meroterpene extracted from Babchi seed, exhibits a

strong repairing effect by stimulating the main components of the dermal-epidermal junction and of the extracellular matrix, promotes hydration, prevents and counteracts inflammation and oxidative stress.

EFFICACY TESTS

Fibroblasts are the main component in the dermis, the deeper layer of the skin, and are responsible for the synthesis of extracellular matrix proteins such as collagen and elastin.We tested the effect of AKOACTIVE NILE LILYNILE LILY on the stimulation of cell proliferation and total protein synthesis in human fibroblasts.

+14%

+5%

+33%

+13%

24 h 48 h

Akoactive Nile Lily 0,02% : effects on human fibroblasts

Protein synthesisCell growth

This evidence suggests a strong role in supporting

deep skin trophism, firmness and vitality.

+ 33% + 33% proteinprotein synthesissynthesis+ 13% + 13% cellcell proliferationproliferation

THE CLAIM

AKOACTIVE NILE LILY...NILE LILY...•anti-oxidant and anti-inflammatory•can improve hydration level and skin texture•can improve vitality, firmness and elasticity•has an active rejuvenating effect

SUGGESTED APPLICATIONS

AKOACTIVE NILE LILYNILE LILY is recommended in selective cosmetics for skin-care (face creams, hand creams, beauty masks, décolleté and body treatment), high-end sun-care, functional make-up (active lipsticks, anti-age foundations), luxury SPA products.

RECOMMENDED DOSAGE: 0,1 – 2%

“From the Peninsula Italica the Secrets of the Actives

from the Ancient Valuesfor a TASTY COSMETOLOGYTASTY COSMETOLOGY”

®®AKOACTIVEAKOACTIVE ITALINEITALINE--TT®®AKOACTIVEAKOACTIVE ITALINEITALINE--T PLUST PLUS

WATER and SUN are the essence of Italy and Tomato, the gorgeous richness of the South of Italy, draws from them both.

Tomato takes its life from the warmest Italian sun and at the same time knows how to defend from its power.

AKOACTIVEAKOACTIVE ITALINEITALINE--TT is the ALL-NATURAL way of preserving our youth and caring for ourselves.

AKOACTIVEAKOACTIVE ITALINEITALINE--TT is a LIPOACTIVE obtained from the seed of GMO-free Italian tomatoes, selected for their organoleptic properties, and grown in accordance with EU standards.

It is manufactured through cold mechanical pressingcold mechanical pressing, decantation and filtration without using any solvents or added chemicals.This ““GreenGreen”” manufacturing process manufacturing process maintains all the nutrients naturally present in the tomatoes, and results in a pure and 100% natural ACTIVE ingredient with the highest possible concentration of all its active components.

The entire manufacturing process is carried out in Italy, after harvesting the tomatoes in their natural habitat of Apulia, far from environmental pollutants.

MANUFACTURING PROCESSMANUFACTURING PROCESS

CHARACTERISTICSCHARACTERISTICSINCI Name: Solanum LycopersicumSeed OilCAS NO.: 90131-63-8 EINECS: 290-375-9 Appearance: viscous liquidColor: red/orangeOdor: characteristic

THE CLAIMTHE CLAIMRejuvenates aging skin, restores skin

antioxidant defences, quenches UV

induced free radicals, protects against

acute and chronic skin photo-damage

ACTIVE COMPONENTS RANGE BENEFITS

Oleic Acid

Linoleic Acid -Omega 6

Linolenic Acid-Omega 3

Palmitic Acid

16-26%

50-60%

1-3%

12-15%

Sebum-like fatty acids that form a protective barrier from external agents providing a soothing effect and improving hydration

Tocopherols 1000-1500 mg/Kg

Excellent antioxidants that help reverse photoageing damage caused be UV exposure

Lycopene 100-200 mg/Kg

Rich in trans-lycopene, powerful radical-scavenger and inhibitor of collagen degradation

Other Carotenoids 50-100mg/Kg

Anti-oxidant effects

Phytosterols 4000-4700 mg/Kg

Vegetal sterols that improve the skin tonicity by increasing the production of elastin

EFFICACY TESTIN VITRO FREE-RADICAL SCAVENGER ACTIVITYThis test ascertains the ability of a cosmetic ingredient to counteract the effects of peroxide radical on human cultured keratinocytes (NCTC 2544). It is predictive of the potentiality of such product to reduce the cellular damage induced by oxidative stress, and it substantiates anti-radical, anti-ageing claims.

SAFETY TESTSIn vitro: CYTOTOXICITY TEST, Italine-T didn’t induce toxicity in cultured keratinocytes.

In vivo: 36 hrs. PATCH TEST, Italine-T was proved topossess no irritant potential.

Cell viability upon treatment with Italine-T

0

20

40

60

80

100

120

140

CONTROL ITALINE-T

Viab

ility

(%)

ITALINEITALINE--T is a natural T is a natural FREEFREE--RADICAL SCAVENGERRADICAL SCAVENGER

Radical Scavenging ability

0

5

10

15

20

25

30

35

40

45

ITALINE-T +H2O2

CARCININE +H2O2

ROS

Inhi

bitio

n (%

)

Italine-T reduces ROS levels

0

500

1000

1500

2000

2500

3000

3500

4000

4500

5000

CONTROL CONTROL +H2O2

ITALINE-T +H2O2

CARCININE+ H2O2

ROS

leve

ls (%

)

2% ITALINE-T

AKOACTIVEAKOACTIVE ITALINEITALINE--T T PLUSPLUSIITALINETALINE--TT was combined with a powerful anti-inflammatory molecule -ALPHA LIPOIC ACID ALPHA LIPOIC ACID -- found in BROCCOLI sprouts, another traditional vegetable fromItalian culture.

“The TASTY SINERGY TASTY SINERGY from the Ancient Valuesdelivers an enhanced LIPOACTIVE with EXCEPTIONAL radical scavenger activity”

LINE EXTENSIONLINE EXTENSION

ITALINEITALINE--T PLUS is a powerful T PLUS is a powerful ANTIANTI--OXIDANT + ANTIOXIDANT + ANTI--

AGEING INGREDIENTAGEING INGREDIENT

+25,5%

+10,6%

+4,4%

ITALINE-T PLUS 0,025%

ITALINE-T PLUS: inhibition of UVA-induced ROS

UVA = 1 J/cm2UVA = 3 J/cm2UVA = 5 J/cm2

+23,7%

+17,0%

+28,1%

+15,2%

0,05% 0,1%

ITALINE-T PLUS: effects onhuman keratinocytes

cell growthprotein synthesis

The ITALINE-T LINE can be widely used in

personal care:

• anti-ageing creams

• body lotions

• moisturizing hair products

• sun care formulations.

In addition it ensures a

positive consumer perception

associated to the Naturality and to

100% Active Ingredient claim.

APPLICATIONS APPLICATIONS

THANKS FOR YOUR ATTENTION!THANKS FOR YOUR ATTENTION!