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1 College of Pharmacy and Nursing School of Pharmacy ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus Spring 2015-2016 Dr.Afaf Mohammed Weli \

ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

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Page 1: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

1

College of Pharmacy and Nursing

School of Pharmacy

ADVANCED PHYTOTHERAPY

(PHCY: 461)

Course syllabus

Spring 2015-2016

Dr.Afaf Mohammed Weli

\

Page 2: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

2

Course Syllabus

COURSE NAME

: Advanced Phytotherapy

COURSE CODE : PHCY 461

CREDIT : 2

CONTACT

HOURS

: 2

PREREQUISITE : PHCY 460

LEARNING

OUTCOMES

: At the end of this course, students are able to:

After completing this course, the student will be able to:

1. Define Phytotherapy.

2. Discuss the advantages and disadvantages of Phytotherapy.

3. Illustrate the natural products proven effective for the treatment of

respiratory diseases.

4. Illustrate the natural products proven effective for the treatment of

CNS diseases.

5. Illustrate the natural products proven effective for the treatment of

GIT diseases.

6. Illustrate the natural products proven effective for the treatment of

infectious diseases..

7. Illustrate the natural products proven effective for the treatment of

musculo-skeletal diseases.

8. Illustrate the natural products proven effective for the treatment of

cancer.

9. Illustrate the natural products proven effective for improving

immunity.

10. Illustrate the natural products proven effective for the treatment of

skin diseases.

11. Illustrate the natural products proven effective for the treatment of

CV diseases.

Doc.

Ref. No.

Issue

Version

Date

UoN-

STC-CS

1 June 2009

Page 3: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

3

SYNOPSIS :

CONTENTS

LECTURES : 1. topic 1

Defination of Phytotherapy

(1 hours)

Details of Topic 1

Introduction and types of Phytotherapy

2. topic 2

Advantages and disadvantages of Phytotherapy

(1 hours)

Details of Topic 2

Advantages and disadvantages of Phytotherapy

3. topic 3

Treatment of respiratory diseases with natural products

(2 hours)

Details of Topic 3

Official names, synonyms biological sources, identification, chemical

constituents, uses, precautions, adverse reactions, contraindications and

toxicity of drugs of respiratory diseases

1. Expectorants

2. Antitussives

3. Bronchodilators

4. topic 4

Treatment of CNS diseases with natural products

(2 hours)

Details of Topic 4

Official names, synonyms biological sources, identification, chemical

constituents, uses, precautions, adverse reactions, contraindications and

toxicity of drugs of CNS

1 Hypnotics

2 Antidepressant

3. Stimulants

4. Analgesics

5.Migran

Page 4: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

4

5. topic 5

Treatment of GIT diseases with natural products

(2 hours)

Details of Topic 5

Official names, synonyms biological sources, identification, chemical

constituents, uses, precautions, adverse reactions, contraindications and

toxicity of drugs of GIT

1. Dyspepsia and liver disorder

2. Constipation

3. Emetics

6. topic 6

Treatment of infectious diseases with natural product

(3 hours)

Details of Topic 6

Official names, synonyms biological sources, identification, chemical

constituents, uses, precautions, adverse reactions, contraindications and

toxicity of drugs for treatment of infectious diseases.

1. Antibacterial drugs

2. Antimalarial drugs

3. Antifungal drugs

7. topic 7

Treatment of musculo-skeletal diseases with natural

product

(2 hours)

Details of Topic 7

Official names, synonyms biological sources, identification, chemical

constituents, uses, precautions, adverse reactions, contraindications and

toxicity of drugs for treatment of musculo-skeletal diseases.

(a) Curare

(b) Colchicum

Page 5: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

5

8.topic 8

Treatment of Cancerous diseases with natural products

(3 hours)

Details of Topic 8

Definition of Cancer, Description, Symptoms, Official names,

synonyms biological sources, identification, chemical

constituents, uses, precautions, adverse reactions,

contraindications and toxicity of drugs for treatment of Cancer

Drugs:

(a)Catharanthus

(b) Taxus (Taxol)

(c) Podophyllum

9. topic 9

Treatment of immunity with the natural products

(2 hours)

Details of Topic 9

Official names, synonyms biological sources, identification,

chemical constituents, uses, precautions, adverse reactions,

contraindications and toxicity of drugs for the treatment of

Immunity

iImmunomodulator :

Immunostimulant,,Immunosuppressant:Adaptogens:

Drugs:Asparagus,Picrorhizakurroa.Echinacea

Withaniasomnifera,Ocimum,Ginseng

10. topic 10

Treatment of skin diseases with natural product.

(2 hours)

Details of Topic 10

1. Official names, synonyms biological sources,

identification, chemical constituents, uses, precautions,

adverse reactions, contraindications and toxicity of

drugs for skin diseases., like Olive, Wool fat Yellow

Bees wax, Arachis oil

Page 6: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

6

11. topic 11

Treatment of cardiovascular diseases with natural

products.

(4 hours)

Details of Topic 11

Major classifications are:

(1) Heart failure and arrhythmias

(2) Venous insufficiency

(3) Antiplatelet and anti-atherosclerotic drug:

Official names, synonyms biological sources, identification,

chemical constituents, uses, precautions, adverse reactions,

contraindications and toxicity of drugs for the treatment of

CVS diseases. like digitalis,Bilberry Horse chestnut, Garlic

Total 24 hours

Page 7: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

7

ASSESSMENTS :

Course Work

Theory (100%)

In semester 1 20

In semester 2 20

Project

Assignment and

presentation

20

Final Exam 40

Total 100

Final Examination

40%

REFERENCES : 1.Textbook Title:

1. W.C. Evans. Trease and Evan’s Pharmacognosy, 16th

edition. London.

2. Jean Bruneton, Pharmacognosy, Phytochemistry, Medicinal

Plants 2nd

edition.

3. J. E. Roberts et al., Pharmacognosy and

Pharmacobiotechnology (1996)

4. Phytochemical methods, J. Harborne (2005)

5. PDR for Herbal Medicines 2nd

edition

6. M.Ali., Test Book of Pharmacognosy latest Edition.

7. Mark Bluenthal. Herbal Medicine, Expanded Commission

E. Monograph (2000).

8. Schulz, Hansel,Tyler. Rational Phytotherapy,Fourth edition

2.References:

1.U.S.P.(the Latest Edition)

2.B.P. (the Latest Edition)

Text Book

3.Internet :

1.www.phcog.org

2.www.ars-grin.gov/duke/index.html

3 www.hort.purdue.edu/newcrop/med-aro/default.html

4. www.herbmed.com

5. www.pubmed.com

Additional

references

Page 8: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

8

TEACHING & ASSESSMENT PLAN

1. College : Pharmacy and Nursing

2. Department : Pharmacy

3. Semester : Spring 2015-16

4. Course Code : PHCY 461

5. Course Name : Advanced Phytotherapy

6. Timetable :

DayTimeClass Room

THURSDAY

10:00-12:00 AM

34-1

7. Faculty Name : Dr.Afaf Mohammed Weli

8. Office No. : 33-14

9. Telephone Ext. : 729

10. E-mail :[email protected]

11. Office hours :DayTime

Monday

09:00-04:00

Wednesday 09:00-04:00

Doc. Ref. No. Issue Version Date

UoN-STC-T&A 1 June 2009

Page 9: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

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12. Text Book & References :

Text Book References

1.Textbook Title:

1. W.C. Evans. Trease and Evan’s

Pharmacognosy, 12th

edition. London.

2. Jean Bruneton, Pharmacognosy,

Phytochemistry, Medicinal Plants (1999)

3. J. E. Roberts et al., Pharmacognosy and

Pharmacobiotechnology (1996)

4. Phytochemical methods, J. Harborne

(2005)

5. PDR for Herbal Medicines 2nd

edition

2.References:

1.U.S.P.(the Latest Edition)

2. B.P. (the Latest Edition)

3.References:

Internet :

1. www.phcog.org

2. www.ars-grin.gov/duke/index.html

3.www.hort.purdue.edu/newcrop/med-

aro/default.htmll

13. Course Description

This course offers the fundamentals of phytotherapy, natural products of verified

pharmacological effect with their mechanisms, active ingredients are obtained from

natural products and acting as bronchodilators, decongestants, inhalants, anti-allergic,

expectorants, cough suppressants, hypnotics, sedatives, antidepressants, stimulants,

analgesics, migraine-treating, tonics, cognitive enhancer, antiprotozoal, antiviral,

antibacterial, antifungal, urinary antiseptic, insecticidal, phytoestrogen, or used for the

treatment of hormonal balance, arthritis , gout, general inflammation, skin inflammation,

dry skin, cancer chemoprotection,immunity problemsand cardiac diseases will be studied

concerning mechanism of action, rational use, constituents, administration, adverse

effects and interaction.

.

14. Assessment Policy

Assessment process takes direct and indirect measurements to ensure that learning

outcomes and program objectives have been achieved. The assessment includes

Page 10: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

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assignments, quizzes, tests, projects and discussions. The type of assessment is indicated

in the weekly plan table and the assessment details are as follows:

Assessment Details:

Assessment Marks (60) Due

In semester 1 20 Week 6

In semester 2 20 Week 11

Assignment Project &

Presentation

20 Week 15

Final Exam 40 Week 17

15. Plagiarism policy

As per the University Policy UoN-STC-CR-1-2009, the following actions(not limited to),

without proper attribution (quoting and/or referencing), will attract stringent penalties:

1. Copy the work of another student;

2. Directly copy any part of another person’s work;

3. Summarize another person’s work;

4. use or develop an idea or thesis derived from another person’s work; or

5. Use experimental results or data obtained or gathered by another person.

6. Cheat during an exam

16. Attendance policy

As per the University Absentee Regulations Uon-RR-AP-1-2009, Absentee warning

notice will be issued to the student according to:

1. “Absentee Warning 1” has to be issued to student who has missed 5% of

course contact hours.

2. “Absentee Warning 2” has to be issued to student who has missed 10% of

course contact hours.

3. “Drop one Grade” has to be issued to student who has missed 15% of course

contact hours.

4. “Barred from Examination” has to be issued to student who has missed 25%

of course contact hours.

17. Weekly Teaching & Assessment Plan:

Page 11: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

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Week

No

Topic Course Outcome Assessment of

Outcomes

1

Introduction and

types of

Phytotherapy

The student should be able to define

Phytotherapy,

The student should be able to classify the

types of Phytotherapy.

Ref: Medicinal Plants Introduction: page

no: 1-28

Schulz: page no: 1-8

oral discussion

2

Advantages and

disadvantages of

Phytotherapy

The student should be able to know the

significances of Phytotherapy and what are

the draw backs or limitations.

Ref: Natural Product Radiance. Page no:

55-63

Quiz, oral discussion

3

Treatment of

respiratory

diseases with

natural products

The students should able to know the

different classifications of drugs

regarding treatment of respiratory

diseases and know about the drugs like

Official names, synonyms biological

sources, identification, chemical

constituents, uses, precautions, adverse

reactions, contraindications and toxicity

of drugs of respiratory diseases like

Expectorants, Antitussives, And

Bronchodilators.

Ref: M Rigat, Page no: 411–422

Schulz: page no: 169-198

Quiz, oral discussion

4

Treatment of

CNS diseases

with natural

products

The students should able to know the

different classifications of drugs

regarding treatment of CNS diseases and

know about the drugs like

Official names, synonyms biological

sources, identification, chemical

constituents, uses, precautions, adverse

reactions, contraindications and toxicity

of drugs of CNS like ,Hypnotics,

Quiz, oral discussion

Page 12: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

12

Antidepressant, Stimulants, Analgesics

and, Migraine

Reference:

Schulz: page no: 41-103

5

Treatment of GIT

diseases with

natural products

The students should able to know the

different classifications of drugs

regarding treatment of GIT diseases and

know about the drugs like

Official names, synonyms biological

sources, identification, chemical

constituents, uses, precautions, adverse

reactions, contraindications and toxicity

of drugs of GIT like Dyspepsia and liver

disorder, Constipation and Emetics.

Reference:

Schulz: page no: 203-263

Quizzes, oral

discussion

6

Treatment of

infectious

diseases with

natural product

The students should able to know the

different classifications of drugs

regarding treatment of Infectious

diseases and know about the drugs like

Official names, synonyms biological

sources, identification, chemical

constituents, uses, precautions, adverse

reactions, contraindications and toxicity

of drugs for treatment of infectious

diseases like Antibacterial drugs,

Antimalarial drugs and Antifungal drugs.

Ref:

Trease and Evans, page no: 428-435

Quizzes, oral

discussion

Insemester exam

7

Treatment of

musculo-skeletal

diseases with

natural product

The students should be able to know about

the drugs like

Official names, synonyms biological

sources, identification, chemical

constituents, uses, precautions, adverse

reactions, contraindications and toxicity of

drugs for treatment of musculo-skeletal

diseases like Curare and Colchicum.

Quizzes, oral

discussion

Page 13: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

13

Ref:

M.Ali: Page no: 340-342, 314-315

8

Treatment of

Cancerous

diseases with

natural products

The students should be able to know about

Definition of Cancer, Description,

Symptoms, Official names, synonyms

biological sources, identification, chemical

constituents, uses, precautions, adverse

reactions, contraindications and toxicity of

drugs for treatment of Cancer drugs like

Catharanthus, Taxus (Taxol)Podophyllum.

Ref: Trease and Evans, Page no: 416-427

Quizzes, oral

discussion

9

Spring Break

10-11

Treatment of

immunity with

natural products.

The students should able to know the

different classifications of drugs containing

Immunity and know about the drugs like

Official names, synonyms biological

sources, identification, chemical

constituents, uses, precautions, adverse

reactions, contraindications and toxicity of

drugs for the treatment of Immunity

iImmunomodulator, immunostimulant

I,Immunosuppressant:Adaptogens:

Drugs:Asparagus,Picrorhizakurroa.Echinac

ea,Withaniasomnifera, Ocimum, Ginseng

Ref:

Schulz: page no: 331-352.

Quizzes, oral

discussion

Insemester 11

Quizzes, oral

discussion

12

Treatment of skin

diseases with

natural product

The students should be able to know about

the drugs like Official names , synonyms

, biological source, identification, chemical

, constituents, uses, precautions, adverse

, adverse reactions, contraindications and

toxicity, of drugs for skin diseases., like

Olive, Wool fat Yellow, Bees wax,

Quizzes, oral

discussion

Page 14: ADVANCED PHYTOTHERAPY (PHCY: 461) Course syllabus

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Arachis oil

Ref:

Schulz: page no: 299-310.

13-14

Treatment of

Cardiovascular

diseases with

natural product

The students should able to know the

different classifications of drugs regarding

treatment of Cardiovascular diseases and

know about the drugs like Official names,

synonyms biological sources, identification,

chemical constituents, uses, precautions,

adverse reactions, contraindications and

toxicity of drugs for the treatment of CVS

diseases. like digitalis,Bilberry Horse

chestnut, Garlic

Ref:

Schulz: page no: 107-167.

Quizzes, oral

discussion

Presentations