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Added Value in Full-text patent files on STN®
Agenda
• Different sources of patent data on STN• Data standardization• Numeric Property Searching (NPS) in patent databases• Key Terms for improved full-text search efficiency• Multi-file case study
‒ Derwent World Patents IndexTM
‒ CaplusSM
‒ INPAFAMDB‒ Full-text Patent Files
Agenda
• Different sources of patent data on STN• Data standardization• Numeric Property Searching (NPS) in patent databases• Key Terms for improved full-text search efficiency• Multi-file case study
‒ Derwent World Patents Index‒ CAplus‒ INPAFAMDB‒ Full-text Patent Files
Benefits of the variety of data sources on STN4
Unique combination of:
(1) Content of various sourcesfirst level patent databases as well as leading value-added databases, andnon-patent literature databases
(2) with sophisticated retrieval capabilitiesincluding structure,biosequence andnumeric searching
… on one platform.
Adding value to patent data sources5
Database producer
• Standardization• Numeric property search• Key terms• Enhanced patent families• Chinese dual filings• Legal status categories• Calculated expiration date
Patent databases on STN6
*w/o full text files # static database value added indexing
Full Text databases National databases* Patent Family databases
• PCTFULL• EPFULL • DEFULL / PATDPAFULL#
• FRFULL• GBFULL• USPATOLD/USPATFULL/USPAT2• AUPATFULL• CNFULL• KRFULL• INFULL• CANPATFULL• JPFULL
• Derwent World Patents Index (DWPI)
• Chemical Abstracts (CA/CAplus)
• INPADOCDB/INPAFAMDB
• PATDPA#
• FRANCEPAT#
• RUSSIAPAT• KOREAPAT• USGENE®• JAPIO #
• …
Benefits of searching full-text patent databases• Increased comprehensiveness
‒ Full text of a publication in a record‒ More publication types ‒ Additional search tools, including numeric property searching in some full-text files
• Improved timeliness• Finding additional details• Finding disruptive technologies• Finding insufficiently indexed subjects or technologies• Finding additional bibliographic information
7
Agenda
• Different sources of patent data on STN• Data standardization• Numeric Property Searching (NPS) in patent databases• Key Terms for improved full-text search efficiency• Multi-file case study
‒ Derwent World Patents Index‒ CAplus‒ INPAFAMDB‒ Full-text Patent Files
STN standardizes formats for patent number and dates
• Patent documents have unique identification numbers:‒ Application number‒ Patent number
• … and documents have dates indicated:‒ Date of filing‒ Publication date‒ Priority date‒ Grant date
9
Data standardization at FIZ Karlsruhe10
• Validation and standardization of numbers according to the standardization table:
‒ >100 patent authorities‒ >2.200 numbering formats for patent and application numbers
• Data harmonization is essential for many processes:‒ Deduplication‒ Patent family sorting‒ Transfer between databases
11
Data standardization at FIZ Karlsruhe
• Take out any periods and the publication kind code; ‒ include the 2-digit country code prefix
• STN has automatic search edits to handle many common formats, e.g. with commas or slashes
• Continuous series‒ Search U.S. 4,718,426 A, as => S US 4,718,426A/PN (searched as US4718426/PN)
• Annual series‒ Search US2019003084, as => S US2019003084/PN (searched as US20190003084 /PN)‒ Search WO 99/00255 A1, as => S WO 99/00255/PN (searched as WO9900255/PN)
S WO1999/255A1/PN (searched as WO9900255/PN)
12
Smart patent number search functionality on STN
• Take out any periods and the publication kind code; ‒ include the 2-digit country code prefix
• STN has automatic search edits to handle many common formats, e.g. with commas or slashes
• Continuous series‒ Search U.S. 4,718,426 A, as => S US 4,718,426A/PN (searched as US4718426/PN)
• Annual series‒ Search US2019003084, as => S US2019003084/PN (searched as US20190003084 /PN)‒ Search WO 99/00255 A1, as => S WO 99/00255/PN (searched as WO9900255/PN)
S WO1999/255A1/PN (searched as WO9900255/PN)
13
Smart patent number search functionality on STN
Search edits on STN
Publication Date (PD) => S 1 MAY 2019/PD 20190501/PD
Publication Date (PD) => S JAN - FEB 2018/PD 20180100-20180299/PD
Publication Year (PY) => S 1998 - 1999/PY 1998-1999/PY
Application Date (AD) => S MARCH 2019/AD 20190300-20190399/AD
Application Year (AY) => S AY < 1991 AY<1991
Priority Date (PRD) => S APRIL 1, 1995/PRD 19950401/PRD
Priority Year (PRY) => S 1987/PRY 1987/PRY
Priority Date First => S 19780401/PRDF 19780401/PRDF
Priority Year First => S PRYF >= 2010 PRYF>=2010
14
Search edits for datesSEARCHED ASTYPED
Agenda
• Different sources of patent data on STN• Data standardization• Numeric Property Searching (NPS) in patent databases• Key Terms for improved full-text search efficiency• Multi-file case study
‒ Derwent World Patents Index‒ Caplus‒ INPAFAMDB‒ Full-text Patent Files
The numeric property search (NPS) – basic facts
16
Properties 59 chemical and physical properties searchable, e.g. percentage, molarity, temperature; more than 1,800 unit variants
Ω
The numeric property search (NPS) – basic facts
17
Properties 59 chemical and physical properties searchable, e.g. percentage, molarity, temperature; more than 1,800 unit variants
Ω
=> HELP NPS => HELP NPS
The Numerical Property Search facility in the KRFULL fileenables numerical searches to be performed for a specific set ofphysical property data having been identified within all Englishtext indexed in the basic index, title, abstract, detaileddescription, and claim fields.
Search field codes and related text for all physical propertiesavailable for numerical property searches have been indexed inthe /PHP search field.
...
/AOS Amount of substance Mol mol/BIR Bit Rate Bit/Second bit/s/BIT Stored Information Bit bit/CAP Capacitance Farad F
...
The numeric property search (NPS) – basic facts
18
Properties 59 chemical and physical properties searchable, e.g. percentage, molarity, temperature; more than 1,800 unit variants
Ω
The numeric property search (NPS) – basic facts
19
Properties 59 chemical and physical properties searchable, e.g. percentage, molarity, temperature; more than 1,800 unit variants
Numeric Analyzer English language text fields=> HELP NPS
Search operators - range, e.g. 10-15nm/SIZ> < greater/less than, e.g. SIZ>10nm=> <= greater/less or equal to, e.g. SIZ<=10nm
Databases - DWPI and 9 patent full text files - 13 NPL files
Ω
Which databases have the NPS feature?
20
=> D CLUSTER NPS => D CLUSTER NPS
CLUSTER NAME CLUSTER DEFINITION----------------- -----------------------------------------------------NPS 1MOBILITY 2MOBILITY AEROSPACE AGRICOLA AUPATFULL CABA
CANPATFULL CNFULL COMPENDEX DEFULL ENCOMPPAT ENCOMPPAT2 FRFULL FSTA GBFULL INFULL JPFULL METADEX PCTFULL PQSCITECH TULSA TULSA2 WPIDS WPINDEX WPIX Numeric Property Searching
The Numeric Analyzer identifies numeric data and normalizes it
21
The resulting CeO2 particle size measured by x-ray diffraction were in the range of 10 to 30 nm. Fig. 1 shows typical nano particles in a sample milled for 6 hours. In a second experiment a 1 litre attrition mill was used for milling the mixture. …
Data normalizationRetrieve above hits in meaningful context
2.16 x104 s
1 x10-3 m3
1 x10-8 m, 3 x10-8 m=> S PARTICLE SIZE (10A) 5-50 NM/LEN
=> S SAMPLE MILL? (2A) 360 MIN/TIM
=> S ATTRITION MILL# (2A) 1000CM**3/VOL
NumericAnalyzer
Search: Typical NPS search syntax
22
operatorConcept search NPS
NaOH molar concentration of 1 - 5 molL-1
AlGaInP LEDs emitting light with a wavelength of 500 - 570 nm
Records containing the following composition: Bi<60%, Pb>20%
S (LED…) (10A) (AlGaInP…) (10A) 500-570 NM/LEN
S (SODIUM HYDROXIDE OR NAOH) (5A) 1-5/CMOL
S ALLOY(S) BISMUTH(1A) PER<60(S) LEAD(1A) PER>20
NPS search field
/LEN
/CMOL
/PER
23
Numeric Property Search – search options
Search tip 1: Specify the unit in your query
24
=> FIL JPFULL
=> S POLYURETHAN# (5A) DEN<25
L1 636 POLYURETHAN# (5A) DEN<25KG/M**3
=> D KWIC=10
L2 ANSWER 1 OF 636 JPFULL COPYRIGHT 2020 QUESTEL/LNU on STN. DETD ...
the seat cushion 4 forms a member, for example a polyurethane foam(density: 10 kg/msup3 -60 Kg/msup3 ) Such as foamed resin can be ...
The base unit for density (/DEN) is kg/m3.
Type D UNIT DEN or HELP NPS to see the default unit(s).
Base units need not be specified.
NPS hits are displayed within the text.
KWIC displays hit terms in the textualcontext: D KWIC
D KWIC=5SET KWIC=10
25
=> FIL JPFULL
=> S POLYURETHAN# (5A) DEN<25
L1 636 POLYURETHAN# (5A) DEN<25KG/M**3
=> D KWIC=10
L2 ANSWER 1 OF 636 JPFULL COPYRIGHT 2020 QUESTEL/LNU on STN. DETD ...
the seat cushion 4 forms a member, for example a polyurethane foam(density: 10 kg/msup3 -60 Kg/msup3 ) Such as foamed resin can be ...
=> S POLYURETHAN# (5A) DEN<25KG/M**3
L2 636 POLYURETHAN# (5A) DEN<25 KG/M**3
Easy to use: Specify the unit in your query and you do not need to look up the default unit.
Search tip 1: Specify the unit in your query
26
=> FIL JPFULL
=> S POLYURETHAN# (5A) DEN<25
L1 636 POLYURETHAN# (5A) DEN<25KG/M**3
=> D KWIC=10
L2 ANSWER 1 OF 636 JPFULL COPYRIGHT 2020 QUESTEL/LNU on STN. DETD ...
the seat cushion 4 forms a member, for example a polyurethane foam(density: 10 kg/msup3 -60 Kg/msup3 ) Such as foamed resin can be ...
=> S POLYURETHAN# (5A) DEN<25KG/M**3
L2 636 POLYURETHAN# (5A) DEN<25 KG/M**3
=> S POLYURETHAN# (5A) DEN<0.025G/CM**3
L3 636 POLYURETHAN# (5A) DEN<0.025G/CM**3
Values in other accepted search units, e.g. g/cm3, are automatically converted.
Easy to use: Specify the unit in your query and you do not need to look up the default unit.
Alternatively: HELP SET UNIT
Search tip 1: Specify the unit in your query
Search tip 2: Search for the presence of a certain property
27
=> FIL FRFULL
=> S LEN/PHP (5A) (LIPOSOM? OR (LIPID? (W) VESICL?))
L1 117 LEN/PHP (5A) (LIPOSOM? OR (LIPID? (W) VESICL?))
=> D KWIC=20
L1 ANSWER 1 OF 117 FRFULL COPYRIGHT 2020 LNU on STN. TIEN DENTAL CEMENTS DISINFECTANTS COMPRISING LIPOSOMES
CLMEN. . . method of preparing a dental cement as defined in one of claims 1 to 5comprising: with] the preparation of liposomes whose size is between20 nm and to 8000 nm, b.] the mixture of said liposomes with a dentalcement in an amount of from. . .
Searching for a property in the Physical Properties (/PHP) field finds all property values and highlights them.
Note: Use E A/PHP 25 to get the whole list of possibilities – including frequencies.
Search tip 3: Use closed ranges instead of exact search
28
=> FIL KRFULL
=> S 100 C/TEMP(3A)(MELTING(W)POINT OR MP)
L1 9464 100 C/TEMP(3A)(MELTING(W)POINT OR MP)
Exact value searched in L1.
Search tip 3: Use closed ranges instead of exact search
29
=> FIL KRFULL
=> S 100 C/TEMP(3A)(MELTING(W)POINT OR MP)
L1 9464 100 C/TEMP(3A)(MELTING(W)POINT OR MP)
=> S 99-101 C/TEMP(3A)(MELTING(W)POINT OR MP)
L2 10328 99-101 C/TEMP(3A)(MELTING(W)POINT OR MP)
Exact value searched in L1.
A closed range searched in L2.
Search tip 3: Use closed ranges instead of exact search
30
=> FIL KRFULL
=> S 100 C/TEMP(3A)(MELTING(W)POINT OR MP)
L1 9464 100 C/TEMP(3A)(MELTING(W)POINT OR MP)
=> S 99-101 C/TEMP(3A)(MELTING(W)POINT OR MP)
L2 10328 99-101 C/TEMP(3A)(MELTING(W)POINT OR MP)
=> S L2 NOT L1
L3 864 L2 NOT L1
=> D 1-10 KWIC=5...
DETD Mp: 101-103 °C
...
DETD Melting point: 100.6-102.6 °C
Exact value searched in L1.
Note: Using exact values (L1) may miss potentially relevant documents
(L3).
A closed range searched in L2.
Use SET TOLERANCE to automatically turn exact values into ranges.
Type HELP SET TOLERANCE for more information.
Search tip 4: Option to exclude indexed open ranges
31
• Physical properties are often given as closed or open ranges (e.g. less than x…). • They are indexed as they come: as closed or open ranges• By default, indexed open ranges are searched.
Search tip 4: Option to exclude indexed open ranges
32
=> FIL JPFULL=> S IRON (2A) PARTICLE (2A) LEN<100nm L1 760=> S IRON (2A) PARTICLE (2A) LEN.EX<100nm L2 447 => S L1 NOT L2 L3 313=> D 1-10 KWIC=8
...first or second 1 to 11, wherein the iron powder, particle size of
100 μm or less, a method for treating water. . ....
The iron based powder, particle size of 212 μm or less arecommon but (-212 μm),. . .
...furnace into the lance, the blast furnace molten iron, averageparticle diameter of 1 mm or less, and/or calcium carbonate of . . .
Note: Open range hits are not always relevant
Option: Exclude indexed open ranges (.EX), as this may helpfocus the search (L2)
• Physical properties are often given as closed or open ranges (e.g. less than x…). • They are indexed as they come: as closed or open ranges• By default, indexed open ranges are searched.
Example: Weight percent of monomers in a copolymer
33
=> FIL PCTFULL
=> S COPOLYM? (15A) ((30-50/PER (2W) (wt or weight percent)) (1A) (ETHYLENE (NOTW) OXIDE)) (5A) ((50-70/PER (2W) (wt or weight percent)) (1A) (PROPYLENE (NOTW) OXIDE))
L1 41
DETDEN 2) obtaining branched propylene copolymers comprising from about 99 to 30wt% propylene, from 1 to 70 wt% ethylene, from 0 to 20 wt% dienemonomer, and a remnant of the metal hydrocarbenyl chain transfer agent,wherein said branched.
Weight percent is indexed in the property Percent (/PER).
To avoid unintended hits, „weight percent“ is searched adjacent to the numericproperty.
Example: Weight percent of monomers in a copolymer
34
=> FIL PCTFULL=> S COPOLYM? (15A) ((30-50/PER (2W) (wt or weight percent)) (1A) (ETHYLENE (NOTW) OXIDE)) (5A) ((50-70/PER (2W) (wt or weight percent)) (1A) (PROPYLENE (NOTW) OXIDE))
L1 41
=> FIL WPIX=> S COPOLYM? (15A) ((30-50/PER (2W) (wt or weight percent)) (1A) (ETHYLENE (NOTW) OXIDE)) (5A) ((50-70/PER (2W) (wt or weight percent)) (1A) (PROPYLENE (NOTW) OXIDE))
L2 505
=> FIL PCTFULL=> TRA L2 1- WITH “WO”L3 TRANSFER L12 1- PNK WITH "WO" : 135 TERMSL4 120 L13
=> S L1 NOT L4
L5 29 L11 NOT L14
Expand your search to different databases
Search in multiple full-text files at once:
=> FIL PCTFULL JPFULL KRFULL=> S COPOLYM? (15A) ((30-50/PER (2W) …
29 unique patent documents in PCTFULL
Agenda
• Different sources of patent data on STN• Data standardization• Numeric Property Searching (NPS) in patent databases• Key Terms for improved full-text search efficiency• Multi-file case study
‒ Derwent World Patents Index‒ CAplus‒ INPAFAMDB‒ Full-text Patent Files
Key Terms make full text searching more efficient• Noun phrases (1-5 words) representing important aspects of a patent:
‒ Extracted from English full-text records using linguistic and statistical methods‒ Sorted according to relevance
• Now available for KRFULL, DEFULL, GBFULL, FRFULL, INFULL, AUPATFULL, CANPATFULL, JPFULL and PCTFULL
• Precise search: Key Terms (/KT) broaden search scope more precisely than Basic Index (/BI) searches
• Quickly analyze documents: Analyze documents to find concurrent and additional concepts as well as not yet perceived aspects
• Efficient relevance check: Key Terms are a good summary, covering the entire text
37
=> S (TRANSDERM? (2W) PATCH?)/...
L1 19 /TI,ABL2 62 /TI,AB,CLML3 385 /BI (searches TI, AB, CLM and DETD)L4 82 /TI,AB,CLM,KT
=> S L4 NOT L2L5 20
=> D KWIC 1-2 KWIC=10
L5 ANSWER 1 OF 20 FRFULL COPYRIGHT 2019 LNU on STN. KT . . .
dermal surface or mucosal membrane; nanoparticles releases photolabileligand; active transdermal patch; biocompatible material lightconductor; active principle; active agent; active substance;. . .
L5 ANSWER 2 OF 20 FRFULL COPYRIGHT 2019 LNU on STN. KT . . .
zone anatomigue lorsgue; low attachment wing; silicones orthosis; outerface transdermal patch; wound dressings and patch; silicone pad;network free vent; low. . .
Key Terms support efficient retrieval and relevance checking
Many hits retrieved in L3 (/BI) are retrieved due to one-time occurrences of the search terms in the field detailed description.
The shown records - retrieved with /KT in addition to /TI,AB,CLM - contain the search terms transdermal patch several times in the full text .
Example: Find relevant French patent document describing transdermal patches.
38
=> S (THREE-DIMENSIONAL PRINTING) OR (3D PRINTER) OR (THREE-DIMENSIONAL PRINTER)
L5 9788 /BI (searches TI, AB, CLM and DETD)
L6 2722 /TI,AB,CLML7 581 /KT
=> S L7 NOT L6
L8 30
=> D KWIC 1-6 KWIC=10
KT ...processing resource; photo or optical detector; multiple device; memoryresource; printing fluid; particulate colorant; ink supply;three-dimensional printing; element or component; non-transitorymachine-readable instruction; threshold and responsive; fiber opticcable; ink delivery system; interference fit mechanism; unaided human...
Retrieve highly relevant hits with Key Terms
Title in value-added database indicates a highly relevant hit:
Apparatus for supporting design of laminate-molded article formed withthree-dimensional printer, has extraction unit which is provided for extracting acceptable tissue condition as input and extracting defective tissue
39
=> FIL JPFULL
=> S CHIMER? (1W) ANTIGEN? (1W) RECEPTOR AND KT/FA
L1 512
=> ANA KT
L2 ANALYZE L1 1- KT: 8664 TERMS
=> D 1-50
TERM # # OCC # DOC % DOC KT------ ------- ------ ------ ---------------
1 161 161 31.45 AMINO ACID SEQUENCE/KT2 97 97 18.95 CHIMERIC ANTIGEN RECEPTOR/KT3 82 82 16.02 CANCER CELL/KT4 81 81 15.82 CELL RECEPTOR/KT5 71 71 13.87 TARGET CELL/KT6 70 70 13.67 HOST CELL/KT7 67 67 13.09 IMMUNE CELL/KT8 67 67 13.09 TUMOR CELL/KT9 63 63 12.30 TRANSMEMBRANE DOMAIN/KT10 62 62 12.11 HEAVY CHAIN VARIABLE REGION/KT ...
Key Terms for query building and data analysis
Further search aspects identified, e.g. cancer cellheavy chain variable region/domain, transmembrane domainintracellular signaling domain...
Example: Find concurrent aspects of chimeric antigen receptors important for further query building
Agenda
• Different sources of patent data on STN• Data standardization• Numeric Property Searching (NPS) in patent databases• Key Terms for improved full-text search efficiency• Multi-file case study
‒ Derwent World Patents Index‒ CAplus‒ INPAFAMDB‒ Full-text Patent Files
Case Study: Anti-Parkinson transdermal patchPatentability of a transdermal patch for the treatment of Parkinson disease with rotigotinesolved with polyvinylpyrrolidone (PVP) particlesof the size from 5 to 100 µm.
41
42
Backing layer
Adhesive layerRelease liner
Transdermal patch
Active compound(Rotigotine with PVP 5-100 µm)
Case Study: Anti-Parkinson transdermal patchPatentability of a transdermal patch for the treatment of Parkinson disease with rotigotinesolved with polyvinylpyrrolidone (PVP) particlesof the size from 5 to 100 µm.
Case Study: Patentability search with three search concepts43
Search strategy – Selection of suitable databases 44
For comprehensive retrieval, use multiple data sources!45
Database content varies in
- subject coverage- coverage of patent authorities and kind codes- timeliness- indexing systems (allowing different search
strategies)- basic documents being indexed
Search strategy – Selection of suitable databases 46
*NPL results not shown in this presentation*
47
Development of search strategy: 1. Transdermal patch
Keywords
Controlled terms(CAS)
Manual Codes (Derwent)
Patent Classifications
48
Efficient keyword searching with STN
=> S TRANSDERM? (3W) PATCH
72627 TRANSDERM?84160 PATCH14312 PATCHES90989 PATCH
(PATCH OR PATCHES)L1 3636 TRANSDERM? (3W) PATCH
Postings provides detailed information about frequency of single and combined search terms.
Identify bottlenecks and broad keywords as well as misspellings!
Keywords
Controlled terms(CAS)
Manual Codes (Derwent)
Patent Classifications
49
Efficient keyword searching with STN
=> S TRANSDERM? (3W) PATCH
72627 TRANSDERM?84160 PATCH14312 PATCHES90989 PATCH
(PATCH OR PATCHES)L1 3636 TRANSDERM? (3W) PATCH
Postings provides detailed information about frequency of single and combined search terms.
Identify bottlenecks and broad keywords as well as misspellings!
Customized settings allow automatic searching of plurals and spelling variations.
3W search terms within 0-3 words in specified order (3636 records)
1W 3259 2W 34923W 36365W 3858AND 6461
Keywords
Controlled terms(CAS)
Manual Codes (Derwent)
Patent Classifications
50
Adjust search profile for precise retrieval
=> S TRANSDERM? (3W) PATCH
72627 TRANSDERM?84160 PATCH14312 PATCHES90989 PATCH
(PATCH OR PATCHES)L1 3636 TRANSDERM? (3W) PATCH
=> D 1-5 KWIC=5
L1 ANSWER 1 OF 3636 TI Transdermal patch useful for pain management, comprises. . .
L1 ANSWER . OF 3636ABEX . . . intravenous route, intravenous drip or transdermal route by
patch, suppository, naso-gastric tube, nasal intestinal. . .
L1 ANSWER . OF 3636ABEX . . . orally, parenterally, intravenously, intramuscularly or
transdermally in form of patch, ointment, lotion, cream, detergent...
L1 ANSWER . OF 3636TI Transdermic-absorption frame-work patch for treating e.g. nausea,
comprises. . .
Keywords
Controlled terms(CAS)
Manual Codes (Derwent)
Patent Classifications
51
Development of search strategy: 1. Transdermal patch
Keywords
Controlled terms(CAS)
Manual Codes (Derwent)
Patent Classifications
=> QUERY (TRANSDERMAL? (5A) (PATCH? OR FORMULATION? OR PLASTER OR (THERAPEUTIC
OR THERAPY OR DELIVERY OR TREATMENT) (W) SYSTEM))
=> QUERY (MEDICATED OR MEDICINAL OR PHARMA?) (2A) (PATCH? OR PLASTER)
=> QUERY TRANSDERMAL?(2A)(PREPARA? OR FORMULAT? OR COMPOSI?)(5A)(ADHES?(2A)LAYER)
Review records for additional search terms
52
Manual Codes (MC) is a granular indexing system
• An in-depth indexing system • Multi-level hierarchical structure: ANN-ANNANA/MC• Consistent indexing throughout the entire database• More detailed and faster indexing possibilities than IPC,
CPC• Code hierarchies are updated annually
Keywords
Controlled terms(CAS)
Manual Codes (Derwent)
Patent Classifications
53
Efficient retrieval of relevant documents by Manual Codes
=> S TRANSDERM? (3W) PATCH
L1 3636 TRANSDERM? (3W) PATCH
=> S B12-M02F/MC
L2 8525 B12-M02F/MC
=> S L2 NOT L1
L3 7164 L2 NOT L1
=> D TI
TI Drug penetration apparatus for permeating chemical agent into the skin hasfourth electrode that applies predetermined voltage to other portions ofskin surface of individual between the third electrodes in contact state
B12 DIAGNOSTICS AND FORMULATION TYPES (THERAPEUTIC, PESTICIDAL, HERBICIDAL)
B12-M FORMULATIONS TYPEB12-M02 CREAM, OINTMENT, PLASTERB12-M02F TRANSDERMAL
Keywords
Controlled terms(CAS)
Manual Codes (Derwent)
Patent Classifications
54
Use the CA Lexicon to build search queries
Keywords
Controlled terms(CAS)
Manual Codes (Derwent)
Patent Classifications
55
Controlled terms of CA Lexicon in the INDEX TERM (/IT) field
Keywords
Controlled terms(CAS)
Manual Codes (Derwent)
Patent Classifications
=> S TRANSDERMAL DRUG DELIVERY SYSTEMS+NT/CT
...
TI Transdermally absorbable rotigotine patch comprising drug reservoirlayer and rubber adhesive layer, and method for producing same
PA Nipro Corporation, JapanPI WO 2018199015 A1 20181101 WO 2018-JP16441 20180423...
IT PolysiloxanesRL: THU (Therapeutic use); BIOL (Biological study); USES (Uses)
(release liner treated with; transdermally absorbablerotigotine patch comprising drug reservoir layer and rubberadhesive layer, and method for producing same)
IT Pharmaceutical patchesTransdermal drug delivery systems(transdermally absorbable rotigotine patch comprising drugreservoir layer and rubber adhesive layer, and method for producingsame)
IT Butyl rubber...
56
Development of search strategy: 1. Transdermal patch
Keywords
Controlled terms(CAS)
Manual Codes (Derwent)
Patent Classifications
=> QUERY (TRANSDERMAL? (5A) (PATCH? OR FORMULATION? OR PLASTER OR (THERAPEUTIC
OR THERAPY OR DELIVERY OR TREATMENT) (W) SYSTEM))
=> QUERY (MEDICATED OR MEDICINAL OR PHARMA?) (2A) (PATCH? OR PLASTER)
=> QUERY TRANSDERMAL?(2A)(PREPARA? OR FORMULAT? OR COMPOSI?)(5A)(ADHES?(2A)LAYER)
=> QUERY B12-M02F/MC OR B12-M02D/MC
=> QUERY TRANSDERMAL DRUG DELIVERY SYSTEMS+NT/CT
=> QUERY DRUG DELIVERY SYSTEMS (L) TRANSDERMAL/CT
=> QUERY A61K0009-7023+NT/CPC
=> QUERY (A61K0009-70 401 OR AG1K0009-70 405)/FCL
=> QUERY (4C076/AA74 OR 4C076/AA74)/FTRM
57
Search concept 2: The active compound rotigotine
Rotigotine
58
Chemistry in patents – High diversity!
Rotigotine
Different chemical names
Chemical Name: (6S)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
International Non-proprietary Name (INN): Rotigotine
Trade Name: Neupro®, Leganto®, Nubrenza®
CAS Registry Number: 99755-59-6
Computed descriptors: CCCN(CCC1=CC=CS1)C2CCC3=C(C2)C=CC=C3O
Different representations & locations
Text, images, tables, reaction schemes, attachments or Markush
59
Search concept 2: The active compound rotigotine
Keywords
Controlled terms(CAS)
Structuresearch
=> QUERY ROTIGOTIN? OR NEUPRO OR N0923 OR N(W)0923 OR SPM962 OR SPM(W)962
=> QUERY (NEUROPROTECTIV? OR NEURO(W)PROTECTIV?)(2A)(AGENT? OR DRUG? OR
COMPOUND?) OR NEUROPROTECTANT? OR NEURO(W)PROTECTANT? OR
(DOPAMINE(2A)RECEPTOR?) OR DOPAMINERGIC?(2A)AGONIST?
specific
generic
=> QUERY NEUROPROTECTIVE AGENTS+NT/CT generic
60
Keywords
Controlled terms(CAS)
Numericproperty search
=> QUERY (POLYVINYLPYRROLIDON# OR POLY(W)VINYL(W)PYRROLIDON# OR
POLY(W)VINYLPYRROLIDON# OR POLYVINYL(W)PYROLIDON#)
=> QUERY (VINYLPYRROLIDON# OR VINYL(W)PYRROLIDON#)(2A)POLYMER?
=> QUERY CROSPOVIDON# OR PVPP
=> QUERY 5-100 MICROMETER/SIZ
=> QUERY "POLY(VINYLPYRROLIDONE)“+ALL/CT
Search concept 3: PVP particles of size from 5-100 µm
Structuresearch
61
Search aspect 3: PVP particles of size from 5-100 µm=> S (POLYVINYLPYRROLIDON# OR POLY(W)VINYL(W)PYRROLIDON# OR
POLY(W)VINYLPYRROLIDON# OR POLYVINYL(W)PYROLIDON#) L153024
=> S (VINYLPYRROLIDON# OR VINYL(W)PYRROLIDON#)(2A)POLYMER? L22532
=> S CROSPOVIDON# OR PVPPL3 6901
=> S L1-3
L4 59704
=> S L4 (5A) 5-100 MICROMETER/SIZ
L5 99
=> D KWIC
TECH . . . probe carrier is stainless steel fiber, quartz fiber, ceramic fiber orglass fiber. Preferred Conditions: The particle diameter of crosslinkedpolyvinylpyrrolidone particles is 1-20 micrometer. The thickness ofthe extraction coating is 20-200 micrometer. Preferred Process: The methodfurther involves soaking probe carrier in. . .
Searching PVP with keywords
Combining all search terms
Refining answer set by numeric property search
Evaluating answer sets, e.g. KWIC-Keyword in Context
Overview of results in numbers62
*NPL results not shown in this presentation*
Valuable, relevant results from all sources searched
An example record from DWPI
Value-added information in Derwent enhanced title and abstract
Valuable, relevant results from all sources searched
An example record from DWPI
Additional subscriber data, including Manual Codes
Valuable, relevant results from all sources searched
An example record from HCAPLUS
CAS modified title and abstract provide additional detail
Valuable, relevant results from all sources searched
An example record from HCAPLUS
Value-added information includes detailed chemical indexing for substances
Valuable, relevant results from all sources searched
An example record from INPAFAMDB
INPADOC abstract with hit term highlighting
Valuable, relevant results from all sources searched
An example record from INPAFAMDB
Additional patent family information and recent legal status events from INPAFAMDB
Full-text records provide even more specific information
Title, Key Terms, and Patent Classification Data from AUPATFULL
Full-text records provide even more specific information
Country-specific claim language with hit term highlighting from full-text files…
Full-text records provide even more specific information
… even when the original language might be unfamiliar.
Summary
• STN contains a wide variety of sources of patent data, including value-added databases as well as primary source, full-text data, all on one search platform
• A number of tools can be used to enhance retrieval and display from each of these databases‒ Value-added indexing and classification‒ Numeric Property Searching‒ Key Terms in full-text files
• Multiple files and types of data should be searched for maximum patent searching comprehensiveness
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