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Alternative Splicing of mRNA
• One gene can code for more than one protein
• Exons can be spliced together into a variety of different mRNAs.
8
Eukaryotic gene model: spliced genes
Posttranscriptional modification
5’-CAP, polyA tail, splicing
Open reading frames Mature mRNA contains ORF
All internal exons contain open “read-through”
Pre-start and post-stop sequences are UTRs
Multiple translates One gene – many proteins via alternative splicing
Hand out Biologi Sel, Dr. Oeke Yunita, Apt.