4 Panhellenic Conference

of Oral Medicine & Pathology

THESSALONIKI1 – 2 March 2019

THESSALONIKI CITY HALL

www.oralpathology2019.gr

HELLENIC SOCIETY OF ORAL MEDICINE AND PATHOLOGY

ORAL MEDICINE AND PATHOLOGY:JUNCTION AND INTERACTION

OF MEDICAL AND DENTAL SPECIALTIES

&1st EUROPEAN ASSOCIATION

OF ORAL MEDICINE (EAOM) REGION 5 MEETING

Organized by

Riga Fereou & Andrea Zakou Street, Christina Center1st floor, Office 101, P.C. 58 256, 3732 Limassol, Cyprus

(Τ) +302310226250, +35799812240(E) info@mk-premium.com(W) www.mk-premium.com

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SCIENTIFIC PROGRAMME

FRIDAY MARCH 1st 2019

8:00-8:50 Registrations

MANOLIS ANAGNOSTAKIS HALL 8:50-9:00 Conference Opening-Presidents’ welcome address 9:00-10.00 MORNING SESSION - ROUND TABLE I

Odontogenic cysts and tumors: An update Session Chairs: Kaplan I. - Chrysomali E. Classification and histopathology Akrish S. Imaging Angelopoulos Ch. Management Vachtsevanos K. Discussion

10:00-11:00 MORNING SESSION - ROUND TABLE II

Medication Related Osteonecrosis of the Jaws (MRONJ): Current status Session Chairs: Yarom N. - Nikitakis N.G. Staging of MRONJ Vardas E. Prediction and interpretation of risk of MRONJ in dental interventions: Where are we? Bektas K. Management of MRONJ Melakopoulos I. Discussion

11:00-11:30 BREAK 11:30-12:45 MORNING SESSION - LECTURES Session Chairs: Vidovich J.D. - Angelopoulos Ch.

Prevalence of oral lesions: 20 years of clinical experience of the Oral Medicine Department Faculty of Dental Medicine, Bucharest, Romania Tovaru S. Care coordination between medicine and dentistry improves outcomes in Behçet's disease Mumcu G. Orofacial pain in cancer patients Yarom N. Assessment of MMP-8 in dental practice. A new approach to dental and medical applications Sakellari D. Discussion

12:45-14:00 BREAK 14:00-15:30 AFTERNOON SESSION / E-POSTER PRESENTATIONS

(ENGLISH) Session Chairs: Boras V.V. - Mumcu G.

Tovaru S. – Yarom N.

EP01 MALIGNANT TRANSFORMATION OF ORAL LICHEN PLANUS. CASE REPORT Ioanina Parlatescu, Serban Tovaru, Carmen Nicolae, Elena Coculescu EP02 ORAL POTENTIALLY MALIGNANT DISORDERS IN PATIENTS WITH ORAL cGVHD: A CASE REPORT AND REVIEW OF THE LITERATURE Grigorios Thermos, Anastasia Andreou, Maria Georgaki, Evangelia Piperi, Nikolaos G. Nikitakis

EP03 IMPLANT-SUPPORTED ORAL REHABILITATION OF A PATIENT WITH MILD DYSPLASIA ORAL ERYTHROPLAKIA: A CASE REPORT Meltem Koray EP04 SQUAMOUS CELL CARCINOMA OF THE FLOOR OF MOUTH WITH UNUSUAL CLINICAL PRESENTATION: A CASE REPORT Anestis Chrisostomidis, Eleni-Marina Kalogirou, Konstantinos I. Tosios, Nikolaos G. Nikitakis

EP05 SALIVARY GLAND TUMORS OF THE UPPER LIP: REPORT OF TWO CASES WITH DIFFERENT CLINICAL AND HISTOPATHOLOGIC CHARACTERISTICS Efstathios Pettas, Vasileios Ionas Theofilou, Argyrios Daskalopoulos, Demos Kalyvas, Andreas Lazaris, Nikolaos G. Nikitakis

EP06 THE SPECTRUM OF SPINDLE CELL LESIONS OF THE ORAL MUCOSA-A RETROSPECTIVE CLINICO-PATHOLOGICAL ANALYSIS Lathisia Mamber, Marilena Vered, Abraham Hirshberg, Ilana Kaplan EP07 SPONGIOTIC GINGIVAL HYPERPLASIA: REPORT OF A CASE WITH MULTIFOCAL INVOLVEMENT OF THE UPPER ANTERIOR GINGIVA Foteini Koulouri, Αnna Korakaki, Grigorios Thermos, Vasileios Ionas Theofilou, Argyrios Daskalopoulos, Savvas Titsinides, Nikolaos G. Nikitakis

EP08 TRAUMATIC ULCER DUE TO LIP BITING FOLLOWING DENTAL LOCAL ANESTHESIA: A CASE REPORT Meltem Koray, Arda Ozgon EP09 EXTENSIVE ORAL ULCERATIONS INDUCED BY DENTURE RELINE- A CASE REPORT Noa Stempler, Marina Umansky Sommer, Silvina Friedlander Barenboim, Mor Bar Ilan, Mordechai Findler, Noam Yarom EP10 PALATINE ULCERS IN AN INFANT: BEDNAR’S APHTHAE Anastasia Andreou, Maria Georgaki, Nikolaos G. Nikitakis

EP11 NECROTIZING SIALOMETAPLASIA IN A BULIMIC PATIENT Ina Arie, Osnat Grinstein-Koren, Noam Yarom, Noa Stempler, Shoshana Reiter EP12 SKIN NECROSIS OF THE SUBMENTAL AREA DUE TO A NECROTIZING SOFT TISSUE ODONTOGENIC INFECTION Konstantinos Katoumas, Marinos Makris, Demetrios Moris, Ioannis Dimopoulos

EP13 ORAL HYALINE RING GRANULOMA: REPORT OF A CASE AND REVIEW OF THE LITERATURE Anastasia Andreou, Grigoris Thermos, Evangelia Piperi, Nikolaos G. Nikitakis EP14 MULTIFOCAL LATERAL PERIODONTAL CYSTS: REPORT OF A RARE CASE AND LITERATURE REVIEW Ilias Karveleas, Eleni-Marina Kalogirou, Grigorios Thermos, Konstantinos I. Tosios, Nikolaos G. Nikitakis EP15 CO-EXISTENCE OF GINGIVAL CYST OF THE ADULT WITH PERIPHERAL SQUAMOUS ODONTOGENIC TUMOR? A RARE CASE REPORT Grigorios Thermos, Georgios Mitrou, Evangelia Piperi, Nikolaos G. Nikitakis

EP16 SIMPLE BONE CYST IN THE ANTERIOR MANDIBLE: A CASE REPORT Anestis Chrisostomidis, Eleni-Marina Kalogirou, Ioannis Melakopoulos, Konstantinos I. Tosios, Nikolaos G. Nikitakis EP17 COMPOUND ODONTOMA ASSOCIATED WITH AN IMPACTED PERMANENT MANDIBULAR CANINE: A CASE REPORT Zeynep S. Pekçetin, Meltem Koray EP18 CEMENTOBLASTOMA OF THE MANDIBLE: REPORT OF A CASE Christos Moustakas, Savvas Titsinides, Argyrios Daskalopoulos, Vasileios Ionas Theofilou, Nikolaos G. Nikitakis EP19 CALCIFIED ORGANIC MASSES IN THE HEAD AND NECK REGION. PHLEBOLITHS OR SIALOLITHS? A CASE SERIES PRESENTATION Chara Chatzichalepli, Evanthia Chrysomali, Evangelia Piperi, Nikos Kolomvos, Nikolaos G. Nikitakis EP20 FOREIGN BODY GRANULOMA WITH SOFT TISSUE ABSCESS FORMATION OF THE UPPER LIP RELATED TO COSMETIC FILLERS: REPORT OF A CASE Dimitra Maniati, Polytimi P. Paschalidi, Vasileios Ionas Theofilou, Argyrios Daskalopoulos, Nikolaos G. Nikitakis

ΕP21 SALIVARY FLOW RATES ARE ASSOCIATED WITH ULTRASONOGRAPHIC SCORING OF THE MAJOR SALIVARY GLANDS IN SJOGREN SYNDROME: WHAT IS THE ADDING VALUE OF ULTRASONOGRAPHY? Yasemin Yalçınkaya, Nevsun İnanç, Filiz Türe-Ozdemir, Meral Yay, Uğur Unal, Pamir Atagündüz, Haner Direskeneli, Gonca Mumcu EP22 ACUTE CONTACT AMALGAM ALLERGY ON BOTH ORAL MUCOSA AND SKIN: A CASE REPORT Meltem Koray, Zeynep S. Pekçetin EP23 CO-EXISTENCE OF MULTIPLE SUPERFICIAL MUCOCELES AND ORAL LICHEN PLANUS: REPORT OF TWO CASES AND REVIEW OF THE LITERATURE Harry Gilas, Maria Georgaki, Ioanna Arvanitidou, Evangelia Piperi, Nikolaos G. Nikitakis EP24 SEVERE ORAL LICHENOID REACTION IN YOUNG PATIENT TREATED WITH PEMBROLIZUMAB (KEYTRUDA) Mor Bar Ilan, Tzippy Davidovitch, Noa Ben Ami Stempler, Shoshana Spierer, Marina Sommer Umansky, Noam Yarom EP25 BULLOUS PEMPHIGOID INITIALLY PRESENTING WITH ORAL MANIFESTATIONS: AN UNUSUAL CASE REPORT Marianna Koufatzidou, Eleni-Marina Kalogirou, Dimitra Pittara, Aikaterini Pantelidaki, Konstantinos I. Tosios

EP26 ORAL HEMOCHROMATOSIS, AN UNDERESTIMATED LESION: A CASE REPORT Anestis Chrisostomidis, Athanasios Zakopoulos, Evanthia Chrysomali, Alexandra Sklavounou EP27 CROHN’S DISEASE WITH INITIAL MANIFESTATIONS IN THE ORAL CAVITY. REPORT OF A CASE Athina Poulopoulou, Vasileios Ionas Theofilou, Maria Georgaki, Savvas Titsinides, Nikolaos G. Nikitakis

EP28 LANGERHANS CELL HISTIOCYTOSIS: REPORT OF A DELAYED DIAGNOSED CASE Panagiotis Kavvadias, Maria Kakava, Vasileios Ionas Theofilou, Argyrios Daskalopoulos, Demos Kalyvas, Nikolaos G. Nikitakis

EP29 THE ROLE OF MACROPHAGES IN MEDICATION RELATED OSTEONECROSIS OF THE JAWS. REVIEW OF THE LITERATURE ON IMMUNOHISTOCHEMICAL STUDIES Polytimi Paschalidi, Ioannis Gkouveris, Nikolaos G. Nikitakis EP30 SECONDARY SYPHILIS: REPORT OF A CASE WITH MULTIFOCAL INVOLVEMENT OF THE ORAL CAVITY Chara Karagiorga, Pantelis Fotakis, Vasileios Ionas Theofilou, Savvas Titsinides, Nikolaos G. Nikitakis EP31 LUES MALIGNA: A RARE BUT AGGRESSIVE VARIATION OF SECONDARY SYPHILIS Dimitris Malamos, Eleni Georgakopoulou EP32 AN UNUSUAL CASE OF TMJ GANGLION CYST PRESENTED AS REACTIVE ARTHRITIS Berg Tal, Frenkel Boaz EP33 THE ROLE OF PSYCHIATRIC DISORDERS IN THE ETIOPATHOGENESIS OF BURNING MOUTH SYNDROME Elena Claudia Coculescu, Ioanina Părlătescu, Șerban Țovaru, Carmen Nicolae, Maria Ladea, Diana Sofia Arina, Bogdan-Ioan Coculescu EP34 DENTAL TREATMENT IN GENERAL ANESTHESIA - A RETROSPECTIVE STUDY Vlaho Brailo, Bernard Janković, Marin Lozić, Dragana Gabrić, Tihomir Kuna, Danica Vidović Juras, Vasilije Stambolija, Željko Verzak

EP35 COMPARATIVE EVALUATION OF THE EFFECTIVENESS OF OXIDANTS AND ANTIOXIDANTS ON THE SUCCESS OF THE DENTAL IMPLANTS Zeynep S. Pekçetin, Meltem Koray, Canan Küçükgergin, Yıldız İyidoğan EP36 ODONTOGENIC MYXOMA: A CLINICOPATHOLOGIC ANALYSIS OF 20 CASES Agamemnon Chliaoutakis, Georgios Ntagiantis, Grigorios Thermos, Nikolaos Kolomvos, Evanthia Chrysomali, Alexandra Sklavounou, Nikolaos G. Nikitakis EP37 AMELOBLASTOMA OF THE ANTERIOR MANDIBLE. REPORT OF A CASE AND LITERATURE REVIEW Chara Chatzichalepli, Panagiotis Goutzanis, Nikos Kolomvos

15:30-16:30 AFTERNOON SESSION- Novel Research in Oral Medicine Session Chairs: Czerninski R. - Chrysomali E. Correlation between clinical and magnetic resonance findings in temporomandibular disorders Abdalla-Aslan R. TLR4 and TLR9 immune response in Oral Tongue Squamous Cell Carcinoma: the outcome of a “battle” Daskalopoulos A. Identification of senescent cells in oral diseases using specific lipofuscin staining (Sudan Black B and SenTraGor) as biomarker; application in archival tissue Georgakopoulou E. Mucosal vasculature changes contribute to pathogenesis at early stages of Osteonecrosis of the Jaws Gkouveris I. HLA-DRB1 expression in patients with fissured tongue Kallifatidis A. TGF-β/Smad signaling in jaw odontogenic tumors. Correlation with oral oncogenesis and future perspective considerations Karathanasi V.

16:30-17:00 BREAK 17:00-18:00 AFTERNOON SESSION - Novel Research in Oral Medicine

(cont.) Session Chairs: Michaeli E.- Tosios K.

Antineoplastic effects of nonsteroidal anti-inflammatory drugs in in-vivo oral carcinogenesis models Katoumas K. Cytokine gene polymorphisms in Greek patients with recurrent aphthous ulceration Kounoupis V. Public Health Threats associated with daily dental practice Paraskeva P. Desquamative gingivitis - a clinical sign of mucocutaneous disorders Penta C. Intensity of burning symptoms and salivary cortisol levels in patients with burning mouth syndrome before and after low level laser therapy Škrinjar I. The clinical features of metastatic tumors to the oral cavity Umansky-Sommer M.

HALL OF CITY COUNCIL

14:00-15:00 AFTERNOON SESSION-ROUND TABLE 1 (IN GREEK)

The role of HPV in Oral Health Session Chairs: Agorastos Th.- Poulopoulos A. Current knowledge about HPV Agorastos Th. The role of HPV in oral premalignant lesions Poulopoulos A. The role of HPV in oral cancer Nikitakis N.G. Discussion

15:00-16:30 AFTERNOON SESSION-LECTURES (IN GREEK) Session Chairs: Savvopoulos Ch.- Dabarakis N. Basic laboratory tests for the investigation of systemic diseases with oral manifestations Savvopoulos Ch. Head and neck swellings: Diagnostic approach Delantoni A. Cancer stem cells Andreadis D. Regenerative dentistry Bakopoulou A. Allergic reactions to orthodontic materials Kolokytha O. Emergencies in dental practice Dabarakis N.

16:30-17:00 BREAK 17:00-18:00 AFTERNOON SESSION-ROUND TABLE 2 (IN GREEK)

The role of prevention in Oral Medicine and Pathology Session Chairs: Malamos D.- Diamanti S. The role of prevention in maintaining oral health Papaioannou W.

Common etiologic/predisposing factors of oral disease Malamos D.

Smoking and head and neck cancer: Public awareness Papanicolaou V.

Discussion

18:00-21:15 OPENING CEREMONY

Chairs: Nikitakis N.G. - Poulopoulos A. - Yarom N.

18:00-18:30 WELCOME ADDRESSES

Nikitakis N.G. President of HSOMP-EAOM Poulopoulos Α. President of the Organizing Committee - ΕΑΟΜ Region 5 Representative Yarom N. Chair of the International Scientific Committee - Immediate Past ΕΑΟΜ Region 5 Representative Devliotis A. President of Dental Association of Thessaloniki Zouloumis L. Dean of School of Dentistry of AUTH Dardavesis Th. Dean of School of Health Sciences AUTH Boutaris I. Mayor of Thessaloniki

18:30-19:30 OPENING ROUND TABLE Oral cancer - An update

Epidemiology, clinical features and novel approaches Perisanidis Ch. Imaging Tsiklakis Κ. Management Antoniades Κ.

19:30-20:00 OPENING LECTURE The close links between oral and systemic health Madianos Ph., Dean of School of Dentistry NKUA

20:00-21:00 PRESENTATION AND LECTURES OF HONORED GUESTS

The contribution of dentist in managing forensic cases Nicopoulou-Karayianni Α.

Malignant salivary gland tumors Papadogeorgakis N.

HIV-related salivary gland diseases Kolokotronis A.

21:00-21:15 FRIENDLY WELCOME LECTURE

Thessaloniki, crossroad of people: Aspects of the history of the city Andronikos I. Historian

21:15-22.30 COCKTAIL RECEPTION

SATURDAY MARCH 2nd 2019

MANOLIS ANAGNOSTAKIS HALL

9:00-10.00 MORNING SESSION - ROUND TABLE I

Dental implants in patients with local and systemic diseases: Important clinical considerations Session Chairs: Bektas K. - Piperi E. Dental implants in oral mucosal lesions Koray M.

Dental implants in systemic diseases and irradiated patients Poulopoulos A.

Principles in providing implant supported rehabilitation for diabetic patients Michaeli E.

Discussion

10:00-11:00 MORNING SESSION - ROUND TABLE II Oral Potentially Malignant Disorders (PMDs): Diagnosis and management in the molecular era Session Chairs: Akrish S.- Poulopoulos A. Histopathologic and molecular markers Nikitakis N. Diagnostic tests for oral cancer and potentially malignant disorders - is there an alternative to scalpel biopsy? Cigic L. Management and chemoprevention Czerninski R. Discussion

11:00-11:30 BREAK

11:30-12:45 MORNING SESSION - LECTURES Session Chairs: Koray M.- Papaioannou W.

Langerhans cell histiocytosis in young adult age: An update Brzak L. The mimickers parade: Benign lesions mimicking malignancy and malignancies mimicking benign lesions Kaplan I. Side effects of topical oral medications Boras V.

Dental management prior head and neck radiotherapy Vidovich J.D.

Discussion

12:45-14:00 BREAK 12:45-13:15 SATELLITE SESSION INTERMED (IN GREEK)

The role of healing products in oral diseases Chrysomali E. The importance of topical treatment in the management of xerostomia Piperi E.

14:00-15:00 AFTERNOON SESSION-ROUND TABLE 1 (IN GREEK)

Mucocutaneous diseases with oral mucosal and gingival manifestations Session Chairs: Chrysomali Ε. - Andreadis D. Oral manifestations Chrysomali Ε. Cutaneous manifestations Charalambidis St. Therapeutic approaches Andreadis D. Discussion

15:00-15:30 AFTERNOON SESSION-ROUND TABLE 2 (IN GREEK) Oral and Maxillofacial Histopathology Session Chair: Nikitakis N.G. Oral epithelial dysplasia grading and squamous cell carcinoma subtypes Piperi Ε. Interpreting the histopathology report Tosios Κ.

15:30-16:30 AFTERNOON SESSION-LECTURES (IN GREEK) Session Chairs: Kalyvas D. - Kossioni A. The role of laser in Oral Medicine Kalyvas D. Oral health status of the elderly: an interdisciplinary field Kosioni Α. Ethics in the dental profession Mitsea Α.

Special Care Dentistry and Oral Medicine: A close relationship Zervou F.

16:30-17:00 BREAK

17:00-17:45 AFTERNOON SESSION-ROUND TABLE 3 (IN GREEK) Oral diseases in childhood Session Chairs: Gizani S. - Stoufi E. Diseases with acute manifestations Stoufi Ε. Chronic diseases Μatiakis Α. The role of the pediatric dentist Gkizani S.

17:45-18:45 AFTERNOON SESSION-ROUND TABLE 4 The future of Oral Medicine and Pathology: Postgraduate Training and Formal Recognition Session Chairs: Tsiklakis K. - Nikitakis N.G.

Poulopoulos A. - Zervou F. 18:45-19:00 CLOSING REMARKS – AWARDS

HALL NEROU

12:30-13:30 AFTERNOON SESSION / E-POSTER PRESENTATIONS (GREEK)

Session Chairs: Mitsea A. - Daskalopoulos A.

13:30-14:00 BREAK 14:00-15:30 AFTERNOON SESSION / E-POSTER PRESENTATIONS

(GREEK) Session Chairs: Vardas E. - Kallifatidis A. 15:30-16:30 AFTERNOON SESSION-Clinicopathologic Conference

(CPC) Session Chairs: Piperi E. - Cigic L.

Case 1 2 3

Contributor Titsinides S. Georgaki M. Kalogirou E.M.

Discussant Matziari E. Pavlou A.M. Chatzivasileiou A.

16:30-17:00 BREAK 17:00-17:45 AFTERNOON SESSION-Clinicopathologic Conference

(CPC) (cont.) Session Chairs: Andreadis D. - Brzak B.L.

Case 4 5 6

Contributor Parcharidis E. Kalpakis L. Papadopoulos P.

Discussant Gkilas H. Arvanitidou I. Demir M.

18:45-19:00 CLOSING REMARKS-AWARDS