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610 PATENT ABSTRACTS humidify the gas as it is circulated through the 4893935 humidification chamber under control of a fan. An airlock is provided to allow biological APPARATUS AND METHOD FOR materials to be placed within or removed from OPTICAL DENSITY the chamber. MEASUREMENTS OF BIOMASS PROCESSES 4892831 INOCULATING DEVICE Johnson N Wong assigned to Evergreen Indus- tries Inc An inoculating device having an inoculating loop, an improved streaking portion and a picker. The device is constructed of high impact polystyrene material which is injection molded to form a long thin member. One end of the device comprises a loop. The other end of the device forms a head having a plurality of distinct streaking surfaces. In the preferred embodiment, these distinct streaking surfaces have a convexity and come together to form a common point or apex, for example as in a curved pyramidal shape. 4892832 FILTER BAG FOR MICROBIOLOGICAL EXAMINATION Kiyotaka Omote, Yuich Matsushima, Masami Taki, Harutomo Oshio, Kazuo Shiraishi, Tokyo, Japan assigned to Toppan Printing Co Ltd There is here provided a convenient bag used at the time when microorganisms which adhere to a specimen containing a solid material are extra- cted with a saline solution and are then ex- amined. In this bag, a filter sheet is stuck to plastic film sidewalls so as to extend from the opening inlet to the bottom portion of the sidewalls, so that the bag is divided into two chambers. A specimen and a saline solution are poured into one of the two chambers, and the resulting extract is taken out by a pipet from another chamber. William Mandel, Anthony Dekovich This invention relates to an apparatus, method and system for directly obtaining the optical density of a dynamic biological system over the wide operating range and a wide range of or- ganism mass, compensating for the primary interference factor, agitation and gas bubble for- mation, and thereby obtaining a on-line real time monitoring of cell density to follow the product concentration and progress of the biological reaction system. 4894137 ENZYME ELECTRODE Koich Takizawa, Satosh Nakajima, Masato Arai, Kyoto, Japan assigned to Omron Tateisi Electronics Co An enzyme electrode comprising: an insulative base plate; two or more electrodes formed on the surface of the insulative base plate and each having an exposed portion; an insulative protec- tion film to insulate and protect the electrodes excluding at least those exposed portions; and an immobilized enzyme film to integratedly cover the exposed portions. 4894329 METHOD OF ASSAYING THE BIOACTIVITY OF A THYMIC EXTRACT Linda Harrington-Fowler, Martin Wilder as- signed to Serono Pharmaceutical Partners A method of assaying the bioactivity ofa thymic extract is disclosed. The disclosed method measures the chemiluminescence of macrophage derived from an immune-deficient mouse after stimulation with the sample thymic extract, phagocytic stimulator, and luminescent detec- ting solution. A kit suitable for practicing the method is also disclosed.

4894329 Method of assaying the bioactivity of a thymic extract

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Page 1: 4894329 Method of assaying the bioactivity of a thymic extract

610 PATENT ABSTRACTS

humidify the gas as it is circulated through the 4893935 humidification chamber under control of a fan. An airlock is provided to allow biological A P P A R A T U S A N D M E T H O D F O R materials to be placed within or removed from O P T I C A L D E N S I T Y the chamber. M E A S U R E M E N T S O F B I O M A S S

P R O C E S S E S

4892831

I N O C U L A T I N G D E V I C E

Johnson N Wong assigned to Evergreen Indus- tries Inc

An inoculating device having an inoculating loop, an improved streaking portion and a picker. The device is constructed of high impact polystyrene material which is injection molded to form a long thin member. One end of the device comprises a loop. The other end of the device forms a head having a plurality of distinct streaking surfaces. In the preferred embodiment, these distinct streaking surfaces have a convexity and come together to form a common point or apex, for example as in a curved pyramidal shape.

4892832

F I L T E R B A G F O R M I C R O B I O L O G I C A L

E X A M I N A T I O N

Kiyotaka Omote, Yuich Matsushima, Masami Taki, Harutomo Oshio, Kazuo Shiraishi, Tokyo, Japan assigned to Toppan Printing Co Ltd

There is here provided a convenient bag used at the time when microorganisms which adhere to a specimen containing a solid material are extra- cted with a saline solution and are then ex- amined. In this bag, a filter sheet is stuck to plastic film sidewalls so as to extend from the opening inlet to the bottom portion of the sidewalls, so that the bag is divided into two chambers. A specimen and a saline solution are poured into one of the two chambers, and the resulting extract is taken out by a pipet from another chamber.

William Mandel, Anthony Dekovich

This invention relates to an apparatus, method and system for directly obtaining the optical density of a dynamic biological system over the wide operating range and a wide range of or- ganism mass, compensating for the primary interference factor, agitation and gas bubble for- mation, and thereby obtaining a on-line real time monitoring of cell density to follow the product concentration and progress of the biological reaction system.

4894137

E N Z Y M E E L E C T R O D E

Koich Takizawa, Satosh Nakajima, Masato Arai, Kyoto, Japan assigned to Omron Tateisi Electronics Co

An enzyme electrode comprising: an insulative base plate; two or more electrodes formed on the surface of the insulative base plate and each having an exposed portion; an insulative protec- tion film to insulate and protect the electrodes excluding at least those exposed portions; and an immobilized enzyme film to integratedly cover the exposed portions.

4894329

M E T H O D O F A S S A Y I N G T H E B I O A C T I V I T Y O F A T H Y M I C

E X T R A C T

Linda Harrington-Fowler, Martin Wilder as- signed to Serono Pharmaceutical Partners

A method of assaying the bioactivity ofa thymic extract is disclosed. The disclosed method measures the chemiluminescence of macrophage derived from an immune-deficient mouse after stimulation with the sample thymic extract, phagocytic stimulator, and luminescent detec- ting solution. A kit suitable for practicing the method is also disclosed.