1. ABUDUXIKE, GULIFEIYA, e SYED MOHAMED ALJUNID. 2012. “Development of health biotechnology in developing countries: Can private-sector players be the prime movers?” Biotechnology Advances 30 (6) (novembro): 1589–1601. doi:10.1016/j.biotechadv.2012.05.002.

2. GUZMAN, MARIA G., SCOTT B. HALSTEAD, HARVEY ARTSOB, PHILIPPE BUCHY, JEREMY FARRAR, DUANE J. GUBLER, ELIZABETH HUNSPERGER, ET AL. 2010. “Dengue: a Continuing Global Threat”. Nature Reviews Microbiology 8 (janeiro 12): S7–S16. doi:10.1038/nrmicro2460.

3. HALSTEAD, S. B. 1988. “Pathogenesis of Dengue: Challenges to Molecular Biology”. Science 239 (4839) (janeiro 29): 476–481. doi:10.1126/science.3277268.

4. MAGALHAES, JL, ANTUNES, AMS, E BOECHAT, N. 2012. Tendências Tecnológicas no Setor Farmacêutico: a questão das doenças tropicais negligenciadas - uma perspectiva da P,D&I no Brasil. Vol. 1. Book. Synergia Editora. RJ, 2012.

BIOPROSPECTING IN DENGUE USING WEB BIOPROSPECTING IN DENGUE USING WEB 2.0 TOOLS TO AID IN MANAGEMENT AND 2.0 TOOLS TO AID IN MANAGEMENT AND

TECHNOLOGICAL INNOVATIONTECHNOLOGICAL INNOVATION

BIOPROSPECTING IN DENGUE USING WEB BIOPROSPECTING IN DENGUE USING WEB 2.0 TOOLS TO AID IN MANAGEMENT AND 2.0 TOOLS TO AID IN MANAGEMENT AND

TECHNOLOGICAL INNOVATIONTECHNOLOGICAL INNOVATIONMAGALHÃES, J.L.1,2, QUONIAM, L.2, FERREIRA, P.M.P.3

1Oswaldo Cruz Foudantion/Fiocruz. Brazil; Capes fellow 12.298-3; Visiteurs-post-doctorant Aix-Marseille Université (France). e-mail: jorgemagalhaes@far.fiocruz.br. 2Aix-Marseille Université (France), Professeur des Universités, Université du Sud Toulon-Var; 3Department of Biological Sciences, Campus Senador Helvídio Nunes de Barros;

Federal University of Piauí (Brazil).

Biotechnology advent made it possible to understand in a better way the biodiversity of life to develop a lot of different products mainly in pharmacological terms. According to the United Nations, the life expectancy in the mid-twentieth century has increased up to 20 years. Brazil also presented this improvement in life expectancy. Then, scientific discoveries stimulate global technological development and promote public health programs to advance in quality of life.

Bioprospecting has potential to solve global problems of public health. Systematically and legally, it can be well-defined as a method or means to find, evaluate and explore the diversity of life existing in a certain place, aiming primarily to search genetic and biochemical resources for commercial purposes. Therefore, whereas the democratization of knowledge provided by the Web 2.0 tools using is freely available. Notwithstanding, studies Neglected Diseases (ND), such as Dengue – global reach disease. Research trends in bioprospecting area and specific correlations with

dengue within the PubMed data basis showed that only 1.41% is focused on the theme. Graph 1 shows research trends in Dengue’s area overtime.

Survey database indexed with data analysis and correlations via Web 2.0.

Figure 1: Global health map in Dengue.

Marine compounds can be cited for trends in Dengue treatments as well as pathogens of dengue. Figure 1 demonstrates global health map for Dengue alerts in January/13. On the other hand, figure 2 shows cluster engineering like Carrot® assist identifies trends for bioprospecting and correlations into dengue area.

Figure 2: Foam tree. PubMed Analysis (Fev/13)

More than 1/3 in the world population does not have a position to acquire essential medicines, mainly for ND where the drugs are toxic and very longstanding. This disease combined with social problems perpetuates the poverty in these places. Web 2.0 tools provide a research instrument to analyze the technological tendency in Dengue, indicating the scientific and technological knowledge, global experts, countries and disease alerts.

Graph 1: Number of research on dengue over the years.

Increasing advancement of technology becomes imperative to network for R,D&I. In figure 4 can see the interaction between scientists in research on dengue.

Moreover, it is important not only monitor the technological development but also incidences of the disease on the web, such as social network analysis. Figure 5 shows the topic "dengue" discussed one day on twitter in Rio de Janeiro.

Similarly, figure 6 is shown the number of locations worldwide research that have dengue.

Figure 6: Distribution of research in Dengue

Figure 4: Network for research in Dengue

Figure 5: Dengue on Twitter