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Global Burden of Disease Introduction to Household Water Treatment and Safe Storage, Module 1.2 Dr. Richard Johnston WHO Collaborating Centre for Sanitation and Water in Developing Countries

1.2 Burden of Disease

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Burden of disease of water borne diseases Water and sanitation projects

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Page 1: 1.2 Burden of Disease

Global Burden of Disease

Introduction to Household Water Treatment and Safe Storage, Module 1.2

Dr. Richard Johnston

WHO Collaborating Centre

for Sanitation and Water

in Developing Countries

Page 2: 1.2 Burden of Disease

Introduction to HWTS | 2

● Diseases caused by unsafe water

and sanitation ● Water-borne

● Water-washed

● Water-based

● Water-related

● Global burden of disease ● Mortality

● Morbidity

Introduction

Page 3: 1.2 Burden of Disease

Introduction to HWTS | 3

● 8.4 deaths/1,000 ● 55 million people per year

● 19.9 births/1,000 ● 135 million people per year

● About 1.1% increase per year ● Doubling every 60 years

Birth, taxes, and death

Page 4: 1.2 Burden of Disease

Introduction to HWTS | 4

“Bradley Classification”

●Water-borne

●Water-washed

●Water-based

●Water-related

Disease Classification System

Page 5: 1.2 Burden of Disease

Introduction to HWTS | 5

Water-borne diseases

Caused by ingestion of water

●Diarrheal diseases ● Rotavirus

● Cholera, Shigella

● Cryptosporidiosis

●Hepatitis A and E

●Polio

Improve water quality

Page 6: 1.2 Burden of Disease

Introduction to HWTS | 6

Water-washed diseases

Caused by poor hygiene due to

lack of water

●Most water-borne diseases

●Trachoma

●Acute respiratory infections

Increase water quantity

Page 7: 1.2 Burden of Disease

Introduction to HWTS | 7

Water-based diseases

Caused by parasites which live

part of their life cycle in water

●Schistosomiasis (bilharzia)

●Dracunculiasis (Guinea worm)

Target aquatic organism host

Protect surface water bodies

Page 8: 1.2 Burden of Disease

Introduction to HWTS | 8

Water-related diseases

Caused by insects which breed

in water

●Malaria

●Dengue fever

Remove habitat

Page 9: 1.2 Burden of Disease

Introduction to HWTS | 9

● Many diseases are related to poor

water, sanitation, and hygiene

● Water-borne diseases are caused

by ingestion of contaminated

drinking-water

● HWTS can reduce burden of water-

borne diseases ● Not water-washed, water-based, or water-

related diseases

Summary

Page 10: 1.2 Burden of Disease

Introduction to HWTS | 10

Mini-Quiz

● Arrange the following five diseases in order of the number of deaths per year

Tuberculosis

Diarrheal disease

Lower respiratory

infections

(e.g. pneumonia)

Malaria

Measles

Page 11: 1.2 Burden of Disease

Introduction to HWTS | 11

Mini-Quiz

● Source: WHO in 2014 published figures for 2012.

Tuberculosis

Diarrheal disease

Lower respiratory

infections

Malaria

Measles

935,000

1,498,000

3,051,000

618,000

130,000

Page 12: 1.2 Burden of Disease

Introduction to HWTS | 12

● Causes 1.5 million deaths per year

● 1 in 10 deaths for children < 5 years ● 1,000 child deaths per day

● Second only to respiratory infection

among infectious diseases

● 56% of diarrheal deaths attributed to

inadequate water, sanitation and

hygiene

Diarrheal disease

Page 13: 1.2 Burden of Disease

Introduction to HWTS | 13

Disability Adjusted

Life Years (DALYs)

● DALY = YLL + YLD

● YLL = Years of Life Lost

Number of deaths × Standard

life expectancy at age of death in

years

● YLD = Years Lived with Disability

Number of incident cases ×

Disability weight × Average

duration of the case (years)

Page 14: 1.2 Burden of Disease

Introduction to HWTS | 14

● Diarrhea causes 52.5 M DALYs/year ● 3.1% of global total

● 9% of child disease burden

● India 13.6 M

● China 3.9 M

● Nigeria 3.9 M

● Pakistan 3.3 M

● DRC 3.3 M ● 10% of all DALYs

Diarrheal morbidity

Source: WHO, 2008

Page 15: 1.2 Burden of Disease

Introduction to HWTS | 15

Global Burden of Disease 2010 Study (IHME)

Page 16: 1.2 Burden of Disease

Introduction to HWTS | 16

● Similar approach to WHO methods

● Not endorsed by WHO ● Methods not fully transparent

● Lacked full access to results for evaluation

● Some key differences with WHO

numbers ● Revised disability weights

● No hygiene risk factor

● No disease burden from ‘improved’ water and

sanitation

GDB 2010 Study

Page 17: 1.2 Burden of Disease

Introduction to HWTS | 17

http://www.healthmetricsandevaluation.org/gbd

Page 18: 1.2 Burden of Disease

Introduction to HWTS | 18

● 1.5 million diarrheal deaths

● 89.5 million DALYs ● India 27 M

● DRC 6.4 M

● Nigeria 6.2 M

● Pakistan 5.5 M

● China 1.3 M

● Only 25% diarrheal deaths due to

poor water and sanitation ● Water and sanitation: 0.9% of DALYs

● Hygiene not included

GDB 2010 Study

Page 19: 1.2 Burden of Disease

Introduction to HWTS | 19

● Burden of disease from poor WASH

is high

● Diarrheal disease is a leading cause

of mortality and morbidity

● Different online resources

● Next: Microbial Water Quality

Conclusion