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www.scmr.org 11 TH A NNUAL S CIENTIFIC S ESSIONS J ANUARY 31–F EBRUARY 3, 2008 Hyatt Regency Century Plaza California F INAL PROGRAM Sponsored by UNIVERSITY OF MINNESOTA

11TH ANNUAL SCIENTIFIC SESSIONS JANUARY 31–FEBRUARY … · 2019. 1. 30. · Hajime Sakuma, MD Mie University Hospital Japan Jürg Schwitter, MD University Hospital Zurich Switzerland

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Page 1: 11TH ANNUAL SCIENTIFIC SESSIONS JANUARY 31–FEBRUARY … · 2019. 1. 30. · Hajime Sakuma, MD Mie University Hospital Japan Jürg Schwitter, MD University Hospital Zurich Switzerland

www.scmr.org

11TH ANNUAL SCIENTIFIC SESSIONS

JANUARY 31–FEBRUARY 3, 2008

Hyatt Regency Century Plaza

California

FINAL PROGRAM

Sponsored byUNIVERSITY OF MINNESOTA

Page 2: 11TH ANNUAL SCIENTIFIC SESSIONS JANUARY 31–FEBRUARY … · 2019. 1. 30. · Hajime Sakuma, MD Mie University Hospital Japan Jürg Schwitter, MD University Hospital Zurich Switzerland

SCMRSociety for Cardiovascular Magnetic Resonance

OfficersPresidentStefan Neubauer, MDJohn Radcliffe HospitalUnited Kingdom

Vice PresidentCharles B. Higgins, MDUCSF Medical CenterUSA

Secretary/TreasurerFrank Rademakers, MD, PhDUniversity Hospitals Leuven Belgium

Vice Secretary/TreasurerChristopher M. Kramer, MDUniversity of VirginiaHealth SystemsUSA

Immediate Past PresidentWarren J. Manning, MDBeth Israel Deaconess Medical CenterUSA

Board MembersAndrew Arai, MDNIH / NHLBIUSA

Jörg Barkhausen, MDUniversity HospitalGermany

David N. Firmin, PhDRoyal Brompton HospitalUnited Kingdom

Scott D. Flamm, MDCleveland ClinicUSA

Matthias G. Friedrich, MDStephenson CMR Centre,University of CalgaryCanada

Michael Jerosch-Herold, PhDBrigham & Women’s HospitalUSA

Joao A.C. Lima, MDJohns Hopkins UniversityUSA

James Moon, MDThe Heart HospitalUnited Kingdom

Eike Nagel, MDKing’s College London United Kingdom

Dudley J. Pennell, MDRoyal Brompton HospitalUnited Kingdom

Hajime Sakuma, MDMie University HospitalJapan

Jürg Schwitter, MDUniversity Hospital ZurichSwitzerland

Mary P. Watkins, RT (MR) (R)C-TRAINUSA

2008 Program CommitteeMatthias G. Friedrich, MDChairStephenson CMR Centre,University of CalgaryCanada

Albert de Roos, MD, PhDCo-ChairLeiden University Medical CenterNetherlands

Stephan Achenbach, MDUniversity of ErlangenGermany

Andrew Arai, MDNIH / NHLBIUSA

Daniel S. Berman, MDCedar Sinai Medical CenterUSA

David Bluemke, MDJohns Hopkins UniversityUSA

Jens Bremerich, MDUniversity Hospital BaselSwitzerland

Peter Buser, MDUniversity Hospital BaselSwitzerland

Ricardo C. Cury, MDMassachusetts General HospitalUSA

Alexander J. Dick, MDSunnybrook HospitalCanada

Rossella Fattori, MDAzienda OspedalieraItaly

Paul Finn, MD, PhDUCLAUSA

Scott D. Flamm, MDCleveland ClinicUSA

Brent A. French, PhDUniversity of VirginiaUSA

Anthony R. Fuisz, MDUniversity of WashingtonUSA

Bernhard Gerber, MDUniversity of BrusselsBelgium

Peter Kellman, PhDNIH / NHLBIUSA

Raymond Kim, MDDuke Medical CenterUSA

Sebastian Kozerke, PhDUniversity and ETH ZurichSwitzerland

Raymond Kwong, MDBrigham & Women’s HospitalUSA

Robert J. Lederman, MDNIH/NHLBIUSA

Thoralf Niendorf, PhDUniversity of AachenGermany

Sven Plein, MD, PhDUniversity of LeedsUnited Kingdom

Andrew J. Powell, MDChildren’s Hospital BostonUSA

Jürg Schwitter, MDUniversity Hospital ZurichSwitzerland

Daniel Sodickson, MD, PhDNew York Medical CenterUSA

Steven D. Wolff, MD, PhDAdvanced Cardiovascular ImagingUSA

Graham Wright, PhDSunnybrook Health Services CentreCanada

COVER AND INSIDE PHOTO CREDITS:

Image 1:This image is adapted withoutpermission from panels 2A and C in JJ Krueger et alCirculation 2006; 113:1093

Image 2:Image courtesy of P. WinterWashington University School ofMedicine, St. Louis, Missouri

Page 3: 11TH ANNUAL SCIENTIFIC SESSIONS JANUARY 31–FEBRUARY … · 2019. 1. 30. · Hajime Sakuma, MD Mie University Hospital Japan Jürg Schwitter, MD University Hospital Zurich Switzerland

Officers, Board & Program Committee Members . . . . . . Page 2

Welcome . . . . . . . . . . . Page 3

General Information . . . . . . Page 4

SCMR Vision Statement . . . . Page 5

Schedule at a Glance . . . . Pages 6-7

Pre-Conference Workshops . . Pages 8-9

Scientific Sessions . . . . Pages 10-30

Moderated Poster Sessions . . Page 31

Technologist Workshop . . Pages 32-33

Exhibits . . . . . . . . . Pages 34-36

Faculty Disclosures . . . . Pages 37-38

Table of Contents

www.scmr.org 3

SCMRWELCOME / TABLE OF CONTENTS

WelcomeDear friends and colleagues:

On behalf of the 2008 Program Committee, we would like to

welcome you to the 11th Annual Sessions of the Society for

Cardiovascular Magnetic Resonance and to the city of Los

Angeles. The next few days will provide many opportunities

to explore all the possibilities CMR offers, to discuss cutting

edge research and get in touch with CMR peers from around

the world.

This year’s program offers a wide variety of topics and

perspectives. Two pre-conference workshops on Thursday

will offer updates on both the clinical and technical aspects of

CMR. The Opening Plenary will kick off the scientific

program with a discussion on atherosclerosis and what CMR

can contribute. A wide variety of scientific sessions will

follow offering interesting topics and provocative discussions.

We are pleased to have world-wide representation in this

diverse program.

Running simultaneously, the technologist workshop will

provide updates on current protocols, tips and tricks.

Thank you for being a part of this exciting conference. We are

glad you are here and are confident that the next few days will

prove to be the learning and networking highlight of the year!

Matthias G. Friedrich, MD

Program Chair Annual Scientific Sessions of the SCMR 2008

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4 11TH ANNUAL SCIENTIFIC SESSIONS • JANUARY 31–FEBRUARY 3, 2008

SCMR VISION STATEMENT

SCMR Vision Statement

The Society of Cardiovascular Magnetic Resonance (SCMR) aims to be the recognized

representative and advocate for physicians, scientists, and technologists who work in the field

of cardiovascular magnetic resonance (CMR). Its aim is to be seen, both nationally and

internationally, as the principal independent organization committed to the further

development of CMR through education, quality control, research, and training.

The mission of SCMR is to:• Foster optimal clinical effectiveness of CMR through professional education, establishment

of standards for quality assurance and professional training, continued medical education,and development of evidence-based guidelines for its use to enhance patient care andimprove the quality of cardiovascular medical practice.

• Support coordinated research efforts to promote further development and applications of CMR, and to investigate accuracy, effectiveness, and cost-effectiveness in cardiovascular diagnosis.

• Provide a forum for scientific exchange and information on CMR, through organization of anannual international scientific conference and of additional smaller meetings, through publicationof the Journal of Cardiovascular Magnetic Resonance, and through establishing close workingrelationships with societies in related fields.

• Build a strong national and international membership body of physicians, scientists,technologists, administrators and other individuals with interest in clinical applications orresearch in CMR.

• Relevant member services, resources and assistance to enhance the development of the fieldof CMR.

ACKNOWLEDGEMENTSThe Society for Cardiovascular Magnetic Resonance gratefully acknowledges the support of this meeting and its objectives from the following companies:

PLATINUM SUPPORTERSGE Healthcare

Philips Medical SystemsSiemens Medical Solutions

INDUSTRY SUPPORTERSBayer HealthCare PharmaceuticalsToshiba America Medical SystemsMedis Medical Imaging Systems

Heart Imaging Technologies

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www.scmr.org 5

SCMRGENERAL INFORMATION

AdmissionYour name badge is your admission ticket and will be requiredfor access to all annual scientific sessions, including admissionto the exhibit hall and the social event.If you have registered for the Technologist Workshop only, youwill receive a Technologist badge that will only allow you intothe Technologist Workshop.If you have registered for the Pre-Conference Workshops,additional tickets will be included in your registration packet.Registration for workshops will be available onsite.

Registration HoursThe Registration Desk will be located in the Los AngelesBallroom Foyer of the Hyatt Regency Century Plaza Hotel andwill be open as follows:

Wednesday, January 30 18:00 – 20:00Thursday, January 31 07:00 – 18:00Friday, February 1 07:00 – 18:30Saturday, February 2 07:00 – 18:30Sunday, February 3 07:30 – 16:00

ExhibitsThe 11th Annual Sessions of the Society for CardiovascularMagnetic Resonance will provide displays of instrumentation,software, imaging and educational information which will beavailable for viewing and interaction during the meeting. Formore information on the exhibiting companies and for afloorplan of the hall, please see page 33.

HoursFriday, February 1 10:00 – 18:30Saturday, February 2 07:00 – 15:45

Speaker Ready Room The 2008 Program Committee is committed to providingcutting edge technology at the Annual Scientific Meeting withits use of complete Audio Visual Networking capabilities. Eachmeeting room will have a networked desktop computer at thepodium and each presentation will be virtually a click away.Please be sure to visit the speaker ready room at least 24 hoursprior to your presentation. The Speaker Ready Room will belocated in the Coat Room and will be open as follows:

Wednesday, January 30 18:00 – 20:00Thursday, January 31 07:00 – 18:00Friday, February 1 07:00 – 18:00Saturday, February 2 07:00 – 18:00Sunday, February 3 07:00 – 15:00

AccreditationThis activity has been planned and implemented in accordancewith the Essential Areas and Policies of the AccreditationCouncil for Continuing Medical Education (ACCME) throughthe joint sponsorship of the University of Minnesota and theSociety for Cardiovascular Magnetic Resonance. TheUniversity of Minnesota is accredited by the ACCME toprovide continuing medical education for physicians.The University of Minnesota designates credits for thefollowing educational activities:

Physician Pre-Conference8.5 AMA PRACategory 1 Credits™

Non-Clinical Pre-Conference Workshop3.0 AMA PRA Category 1 Credits™

Scientific Sessions21.75 AMA PRA Category 1 Credits™

Physicians should only claim credit commensurate with theextent of their participation

DisclosureIt is the policy of the University of Minnesota Office ofContinuing Medical Education to ensure balance,independence, objectivity and scientific rigor in all of itssponsored educational activities. All participating faculty,course directors, and planning committee members arerequired to disclose to the program audience any financialrelationships related to the subject matter of this program. It isnot necessary to disclose relationships with non-profit orgovernment organizations or proprietary entities that do notproduce health care goods or services. Relationships ofspouse/partner with proprietary entities producing health caregoods or services should be disclosed if they are of a nature thatmay influence the objectivity of the individual in a position tocontrol the content of the CME activity.Disclosure information is reviewed in advance in order tomanage and resolve any possible conflicts of interest. Specificdisclosure information for each course faculty will be sharedwith the audience prior to the faculty's presentation.

Technologist WorkshopApplication has been submitted to The American Society ofRadiological Technologists (ASRT) to award category Acontinuing education units. Each technologist should claimonly those hours of credit actually spent in this activity.

GEN

ERAL

INFO

RMAT

ION

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6 11TH ANNUAL SCIENTIFIC SESSIONS • JANUARY 31–FEBRUARY 3, 2008

SCMR SCMR 2008 SCHEDULE AT A GLANCE

8:00 - 14:30

14:30 - 18:00

Physician Pre-Conference WorkshopIntroduction to Cardiovascular MR

Constellation Ballroom

8:00 - 10:00

10:00 - 10:30

12:00 - 12:30

12:30 - 13:30

13:30 - 15:00

15:00 - 15:30

15:30 - 17:00

17:00 - 18:30

Welcome Address Clinical Plenary Session 1: Cardiovascular Risk Assessment – Defining Better Therapeutic Targets by CMR

Los Angeles Ballroom

Continental Breakfast7:00 - 8:00

Los Angeles Ballroom Foyer

Refreshment Break and Opening of Commercial ExhibitsCalifornia Showroom

Parallel Oral Abstract Session IYoung Investigators Award Session - Clinical

Los Angeles Room

SCMR Business MeetingLos Angeles Room

Lunch on Own / Poster Viewing Session 1California Showroom

Parallel Oral Abstract Session IIYoung Investigators Award Session - Experimental

Beverly Hills Room

Parallel Oral Abstract Session IIIWhat is New in CMR Viability Imaging?

Santa Monica Room

Trainee Hour Parallel Session A: Clinical - Cardiology Trainees

Westside Room

Trainee Hour Parallel Session B: Clinical - Radiology Trainees

Westside Room

Trainee Hour Parallel Session C:Basic - Science Trainees

Westside Room

Parallel Session CLINICALCMR vs CT for Vascular and Coronary Disease

Los Angeles Room

Parallel Session NON-CLINICALNew RF Coil Designs for CMR

Beverly Hills Room

Parallel Oral Abstracts Session IVCMR Data on Prognosis - Here We Are

Santa Monica Room

Parallel Oral Abstract Session VProgress in Coronary CMR Imaging

Los Angeles Room

Parallel Oral Abstract Session VIToward a Better Understanding of Cardiovascular Risk

Beverly Hills Room

Parallel Oral Abstract Session VIINew Methods: The Cutting Edge

Santa Monica Room

Refreshment Break / ExhibitsCalifornia Showroom

Parallel Session CASES TO LEARN FROMLos Angeles Room

Parallel Oral Abstract Session VIIINew Methods Using New Hardware and Software

Beverly Hills Room

Parallel Oral Abstract Session IXNew Vascular Applications

Santa Monica Room

Basic Pre-Conference Workshop:Scanning the Horizon, Emerging Technologies for Cardiovascular Diagnosis

and Intervention Olympic Ballroom I

THURSDAY, JANUARY 31, 2008

FRIDAY, FEBRUARY 1, 2008

7:00 - 8:00 Continental Breakfast / ExhibitsCalifornia Showroom

Coffee With Experts I:What We Do In Acute Coronary Syndrome, Aortic Dissection,

Asymptomatic CAD, RV DilatationBeverly Hills Room

SATURDAY, FEBRUARY 2, 2008

18:00 - 19:00

10:30 - 12:00

Technologist Workshop14:30 - 17:30

Session 1The “How-To” Basics for CMR

Constellation Ballroom

8:00 - 9:30

9:30 - 10:15

Parallel Session CLINICALCMR in Non-Ischemic CMP

Los Angeles Room

CMR Technology Updates Los Angeles Room

10:15 - 10:55 CMR QuestionnaireLos Angeles Room

Parallel Session NON-CLINICALParallel Imaging

Beverly Hills Room

Parallel Session - CONGENITALCMR of Tetralogy of Fallot

Santa Monica RoomTechnologist Workshop

8:00 - 10:40Session II:

Essential Physics for CMRConstellation Ballroom

User Meetings19:00

California Showroom

Moderated Poster Session - Clinical / Poster Session I -Presenters Present / Exhibits - Wine & Cheese Reception

17:30 - 18:30California Showroom

SCHEDULEAT

AGLAN

CE

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www.scmr.org 7

SCMRSCMR 2008 SCHEDULE AT A GLANCE

10:55 - 11:15

11:15 – 12:45

12:45 - 13:45

13:45 - 15:15

15:15 - 15:45

Refreshment Break / ExhibitsCalifornia Showroom

Parallel Oral Abstract Session XCMR of Non-Ischemic Heart Disease I

Los Angeles Room

Lunch on Own / Moderated Poster Session - Experimental / Poster Session II -Presenters Present / Exhibits

California Showroom

Parallel Session CLINICALNew Diagnostic Targets in

Myocardial InfarctionLos Angeles Room

Refreshment Break / ExhibitsCalifornia Showroom

15:45 - 17:15

17:15 - 18:45

19:00

Parallel Session NON-CLINICALMolecular Imaging: Contrast AgentMechanisms and CMR Applications

Beverly Hills Room

Parallel Oral Abstract Session XIIICMR of Non-Ischemic Heart Disease II

Santa Monica Room

Parallel Session - POLITICALNew Codes and New Safety Concerns

Los Angeles Room

Parallel Session - CONGENITALCHD - Indications and Imaging Protocols

Beverly Hills Room

Parallel Oral Abstract Session XIVRefined Phenotyping by CMR

Santa Monica Room

Parallel Session CASESLos Angeles Room

Awards Presentation and ReceptionPlaza Pavilion

Parallel SessionInterventional CMR - 1

Beverly Hills Room

Parallel Oral Abstract Session XVCMR for Myocardial Ischemia

Santa Monica Room

SATURDAY, FEBRUARY 2, 2008 CONTINUED

7:30 - 8:00Coffee with the Experts Session II

What we do in Cardiac Tumor, ARVD, Cardiomyopathy, CHDBeverly Hills Room

7:00 - 8:00 Continental BreakfastLos Angeles Ballroom Foyer

SUNDAY, FEBRUARY 3, 2008

Technologist Workshop11:00 - 13:15

Session III: Understanding and Imaging

Acquired Heart DiseaseConstellation Ballroom

Technologist Workshop14:15 - 16:00

Session IV: Elements of Myocardial Viability

Constellation Ballroom

Technologist Workshop16:15 - 18:00

Session V: CE-MRA/Case StudiesConstellation Ballroom

8:00 - 9:30

9:30 - 10:00

Parallel Session CLINICALFirst-Pass CMR Perfusion

Los Angeles Room

Refreshment BreakLos Angeles Ballroom Foyer

11:45 - 13:00 Lunch on Your Own

Refreshment BreakLos Angeles Ballroom Foyer

13:00 - 14:30

10:00 - 11:45

Parallel Session NON-CLINICALUnmet Needs in CMR

Beverly Hills Room

Parallel Session CASES TO LEARN FROMSanta Monica Room

Parallel Session CLINICALCutting-Edge Vascular CMR

Los Angeles Room

Parallel Session NON-CLINICALMetabolic CMR Studies

Beverly Hills Room

Parallel SessionInterventional CMR - II

Santa Monica Room

Parallel Session CLINICALClinical CMR Endpoints in Clinical Trials

Los Angeles Room

Parallel Session CLINICALCMR @ 3T – Solved and Unsolved Problems

Santa Monica Room

14:30 - 14:45

Clinical Plenary Session 2CMR and Electrophysiology

Los Angeles Ballroom

14:45 - 16:00

Farewell AddressLos Angeles Ballroom

16:00 - 16:15

Technologist Workshop8:00 - 11:25

Session VI: How to Navigate through Congenital Heart Disease

Constellation Ballroom

Technologist Workshop12:30 - 15:00

Session VII: Technologies on the RiseConstellation Ballroom

Parallel Oral Abstract Session XIIn Real Time: Interventions and More

Beverly Hills Room

Parallel Oral Abstract Session XIIWhat is New in Congenital CMR?

Santa Monica Room

SCHE

DULE

ATA

GLAN

CE

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8 11TH ANNUAL SCIENTIFIC SESSIONS • JANUARY 31–FEBRUARY 3, 2008

SCMR PHYSICIAN PRE-CONFERENCE WORKSHOP

8:00 - 8:10 Welcome AddressPeter Buser, MDUniversity Hospital Basel

8:10 - 10:15 MR Physics

8:10 - 8:35 MR Basics: Spins and HardwareHarald Quick, MDUniversity Hospital Essen

8:35 - 9:00 Black-Blood SequencesSteve Shea, PhDSiemens Corporate Research, Inc.

9:00 - 9:25 Bright-Blood SequencesMichael Schär, PhDPhilips Medical Systems & John Hopkins

9:25 - 9:50 Contrast-Enhanced SequencesTom Foo, PhDGE Global Research

9:50 - 10:15 T2-Weighted SequencesAnthony H. Aletras, PhDNIH / LCE-NHLBI

10:45 - 12:30 How to ….

10:45 - 11:00 Get the Correct Slice PositionsMichael Atalay, PhDRhode Island Hospital, Brown University

11:00 - 11:20 Measure Regional and Global LVFunctionRob van der Geest, PhDLeiden University Medical Center

11:20 - 11:40 Perform Flow MeasurementsJoachim Lotz, MDHannover Medical School

11:40 - 12:00 Visualize Myocardial Late EnhancementOliver Strohm, MDStephenson CMR Centre, University of Calgary

12:00 - 12:20 Optimize MR AngiographyProtocolsJames Carr, MDNorthwestern University

12:20 - 12:30 Panel Discussion

12:30 - 13:30 Lunch Break

13:30 - 15:30 Tips and Tricks13:30 - 13:50 Let's Go Faster: Parallel

Acquisition TechniquesBernd M. Wintersperger, MDUniversity Hospitals Munich

13:50 - 14:10 How to Deal With Breathing ArtifactsJens Vogel-Claussen, MDJohns Hopkins University

14:10 - 14:30 Improved Image Quality inArrhythmic PatientsChris Francois, MDUniversity of Wisconsin

14:30 - 14:50 Small Areas of LE: Pathology or Artifact?Tareq Ibrahim, MDGerman Heart Center Munich

14:50 - 15:10 How to Optimize Your WorkflowAndreas Kumar, MDStephenson CMR Centre, University of Calgary

15:10 - 15:30 Key Issues for Good MRCA ExamsGerald F. Greil, MDKing's College London

16:00 - 18:00 Clinical Applications of CMR

16:00 - 16:20 Myocardial IschemiaW. Gregory Hundley, MDWake Forest University School of Medicine

16:20 - 16:40 Myocardial InfarctionHassan Abdel-Aty, MDUniversity of CalgaryCharite, Campus Berlin Buch

16:40 - 17:00 Valvular DiseaseJos Westenberg, MDLeiden University Medical Center

17:00 - 17:20 Characterization of PericardialDiseasesPeter Buser, MDUniversity Hospital Basel

17:20 - 17:40 Cardiomyopathies and MyocarditisDavid Bluemke, MDJohns Hopkins University

17:40 - 18:00 Congenital Heart DiseasePhil Spevak, MDJohns Hopkins University

Thursday, January 31, 2008 8:00 – 18:00Introduction to Cardiovascular MR

Room: Constellation Ballroom

Chairs: Peter Buser, MD, University Hospital Basel; David Bluemke, MD, Johns Hopkins University; Massimo Lombardi, MD, Clinical Physiology Institute and Naeem Merchant, MD, University Health Network

PHYSICIANPRE-CON

FERENCE

WORKSHOP

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www.scmr.org 9

SCMRBASIC PRE-CONFERENCE WORKSHOP

14:30 - 14:35 Welcome and IntroductionDaniel K. Sodickson, MD, PhD

14:35 - 15:35 The Benefits and Limits of Parallelismin MR and CT

14:35 - 15:00 Parallel MRI: How Many Detectorsare Enough?Riccardo LattanziBeth Israel Deaconess Medical Center

15:00 - 15:30 Multidetector-row CT: How ManyDetectors are Enough?Jacob ( Koos) Geleijns, PhDLeiden University Medical Center

15:30 - 15:35 Panel Discussion

15:35- 16:40 Multimodality Approaches to Diagnosisand Therapy

15:35 - 16:40 XMRGabriele Krombach, MDUniversity Hospital Aachen

16:40 - 16:50 Refreshment Break

16:50 - 17:55 Technologies for Molecular Imaging

16:50 - 17:20 Hyperpolarized Contrast Agents for the Cardiovascular SystemPratip Bhattacharya, PhDHuntington Medical Research

17:20 - 17:50 Optical Imaging TechnologiesDavid Sosnovik, MDCenter For Molecular Imaging Research

17:50 - 17:55 Panel Discussion

17:55 - 18:00 ConclusionsThoralf Niendorf, PhD; RWTH Aachen

Basic Pre-Conference Workshop:Scanning the Horizon, Emerging Technologies for

Cardiovascular Diagnosis and InterventionThursday, January 31, 2008 14:30 – 18:00

Room: Olympic Ballroom I

Organizers: Daniel K. Sodickson, MD, PhD; New York Medical CenterThoralf Niendorf, PhD; RWTH Aachen

This session is endorsed by the ISMRM.

BASI

CPR

E-CO

NFE

REN

CEW

ORKS

HOP

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10 11TH ANNUAL SCIENTIFIC SESSIONS • JANUARY 31–FEBRUARY 3, 2008

SCMR SCIENTIFIC SESSIONS

Trainee HourThursday, January 31, 2008

18:00 – 19:00Room: Westside

18:00 18:05 Welcome AddressStefan Neubauer, MD; John Radcliffe Hospital

18:05 19:00 Session A: Clinical Cardiology TraineesModerator: Raymond Kim, MD; Duke Medical Center

Choosing a Training Program and How to Transition to the Real WorldMichael Elliott, MD; St. Vincent Heart Center

18:05 19:00 Session B: Clinical Radiology TraineesModerator: Scott Flamm, MD; Cleveland Clinic Cardiovascular Imaging

Choosing a Training Program and How to Transition to the Real WorldJohn Grizzard, MD; VCU Medical Center

18:05 19:00 Session C: Basic Science TraineesModerator: Dara Kraitchman, VMD, PhD; Johns Hopkins University

Choosing a Training Program and How to Transition to the Real WorldLeon Axel, PhD; NYU Medical Center

SCIENTIFIC SESSIONS

Friday, February 1, 2008

8:00 8:10 Welcome Addresses Los Angeles BallroomStefan Neubauer, MD, SCMR PresidentMatthias G. Friedrich, MD, Program ChairGerald M. Pohost, MD, Inaugural Past-President

8:10 10:10 Clinical Plenary Session 1: Cardiovascular Risk Assessment Los Angeles BallroomDefining Better Therapeutic Targets by CMRModerators: Matthias G. Friedrich, MD; Stephenson CMR Centre, University of Calgary Stefan Neubauer, MD; John Radcliffe Hospital

8:10 8:30 Clinical Cardiovascular Risk Assessment Today - Endpoints, Cans and Can’tsPeter Libby, MD; Brigham and Women's Hospital

8:30 8:50 The Unstable Plaque: The Holy Grail for Non-Invasive Imaging? Zahi Fayad, PhD; Mount Sinai School of Medicine

8:50 9:10 CMR - Derived Markers in the Metabolic SyndromeHildo Lamb, MD, PhD; Leiden University Medical Center

9:10 9:30 The Importance of Microvascular Damage and No Reflow FollowingReperfusion Therapy for Myocardial Infarction Robert A. Kloner, MD; Keck School of Medicine, USC

9:30 9:50 Assessment of End-Organ Damage in Atherosclerosis Joao Lima, MD; Johns Hopkins University

9:50 10:10 Risk Prediction by Visualizing Myocardial Tissue Damage Dudley Pennell, MD; Royal Brompton Hospital

10:10 10:30 Refreshment Break and Exhibits Open California Showroom

FRID

AY

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www.scmr.org 11

SCMRSCIENTIFIC SESSIONS

10:30 12:00 Parallel Oral Abstract Session I: Young Investigators Award Session - Clinical Los Angeles RoomDedicated to Walter RogersModerators: Dudley Pennell, MD; Royal Brompton HospitalWarren J. Manning, MD; Beth Israel Deaconess Medical Center

10:33 10:47 (100) Prognostic Significance of Post-Procedural Irreversible Myocardial InjuryDetected by Cardiovascular Magnetic Resonance ImagingJoseph Selvanayagam, MBBS FRACP DPhil; Flinders University

Even small amounts of procedure-related myocardial injury are associated with poorer mediumterm clinical outcomes. CMR identified myocardial injury may be a stronger prognostic marker thancardiac troponin in the setting of coronary revascularization.

10:47 11:01 (101) Quantifying Aortic Regurgitation with CMR Can Predict PatientsRequiring Aortic Valve SurgerySaul Myerson, MD MRCP FESC; Oxford University

49 patients had their AR quantified with CMR and were followed for up to 5 years. Quantificationof the AR predicted the progression to surgery with high accuracy, and was better than LV volumeor function indices.

11:01 11:15 (102) Diagnostic Value of Contrast-Enhanced Whole-heart Coronary MRA at 3 TeslaQi Yang; Department of Radiology, Xuanwu Hospital, Capital Medical University

Whole heart coronary MRA using a slow infusion 3D IR-Flash technique at 3T was performed in22 patients with suspected coronary artery disease and compared to x-ray coronary angiography.

11:15 11:29 (103) Non-invasive Measurement of Coronary Artery Flow Velocity at Rest andDuring Handgrip Stress in Healthy Subjects Using 3T MRIAllison Hays, MD; Johns Hopkins University

3T spiral MRI enables the quantification of coronary flow velocity changes in response toendothelial-dependent stress with both high temporal and spatial resolutions. In healthy adults,isometric handgrip stress caused a significant increase in peak diastolic coronary flow velocity.

11:29 11:43 (104) Reference Values for Cardiac Index Measured with Magnetic ResonanceImaging in Healthy Subjects and Comparison with Patients withCongestive Heart FailureMarcus Carlsson, MD, PhD; Department of Clinical Physiology

Cardiac index (CI) is lower in patients with congestive heart failure and depressed LV functioncompared to healthy subjects. There is a decrease in CI in healthy subjects with age but CI does notdiffer between males and females.

11:43 11:57 (105) Weight Loss Reverses Aortic Distensibility Changes in Subjects withSevere Uncomplicated Obesity. A One Year Follow Up Study.Oliver Rider; University of Oxford

In the setting of uncomplicated obesity, aortic elastic properties are improved after one year ofweight loss.

10:30 12:00 Parallel Oral Abstract Session II: Young Investigators Award Session – Experimental Beverly Hills RoomDedicated to Frank WiesmannModerator: Orlando Simonetti, PhD; The Ohio State University

Hildo Lamb, MD, PhD; Leiden University Medical Center

10:33 10:47 (106) Weight Loss in Type 2 Diabetes Mellitus is Associated with DecreasedMyocardial Triglyceride Content and Improved Left Ventricular FunctionSebastiaan Hammer; Leiden University Medical Center

Substantial weight loss in severely obese type 2 diabetic patients is associated with a decreasein myocardial triglyceride content and with improvements in myocardial function.

10:47 11:01 (107) Small Field of View Black-Blood Imaging of the Human Heart UsingLocal ExcitationKhaled Abd-Elmoniem, PhD.; Johns Hopkins University

Local excitation is an effective method for small-FOV TSE imaging with the aliasing artifacts can beavoided. 2-D selective excitation pulses are inherently self-refocused and therefore no compromisesin FSE imaging are necessary.

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11:01 11:15 (108) Accelerated 3D Tagging to Assess Left Ventricular Dyssynchrony inPatients with Sub-Acute Myocardial InfarctionsAndrea Rutz; Institute for Biomedical Engineering, University and ETH

An accelerated 3D tagging acquisition was used to quantify left ventricular dyssynchrony in patientswith sub-acute myocardial infarctions relative to a control population. Combined with CMRviability imaging, the approach shows potential to predict individual responsiveness to cardiacresynchronization therapy.

11:15 11:29 (109) Antegrade Percutaneous Closure of Membranous Ventricular SeptalDefect using X-Ray Fused with MRI (XFM)Kanishka Ratnayaka, MD; National Heart, Lung, and Blood Institute

We used MRI-derived roadmaps superimposed on live X-ray to simplify a complex catheter-based treatment of congenital heart disease. This enables crossing a ventricular septal defect(VSD) antegrade (from the morphologic right ventricle), greatly reducing procedure time andradiation exposure.

11:29 11:43 (110) Myofiber Developmental Plasticity in Fetal Hearts Delineated withDiffusion Tensor MRILei Zhang; Washington University in St. Louis

Myofiber structure in fetal hearts is different from that in adult hearts. Balanced contribution ofseptal myofibers from both ventricles of fetal heart was observed, suggesting plasticity of myofiberdevelopment in response to different contractile function before and after birth.

11:43 11:57 (111) Detection of Changes in Myocardial Blood Flow and Volume: A CMRStudy in a Canine Model of Coronary Artery StenosisKyle McCommis, BS; Mallinckrodt Institute of Radiology, Washington University School of Medicine

A quantitative CMR perfusion technique was performed in a canine stenosis model duringDipyridamole or Dobutamine-induced hyperemia to assess changes in both myocardial blood flowand volume. Hyperemia caused different responses in stenotic and normal vessel perfusedmyocardial regions.

10:30 12:00 Parallel Oral Abstract Session III: What is New In CMR Viability Imaging? Santa Monica RoomModerators: Nathaniel Reichek, MD; St. Francis HospitalRobert Judd, PhD; Duke Medical Center

10:33 10:45 (112) Clinical Significance of Phase Encoding Order in Delayed EnhancementCardiac ImagingAmol Pednekar, PhD.; Philips Medical Systems

Clinically significant artificial hyperenhancement due to edge enhancement and ringing resultingfrom low-high profile order is suppressed by using linear profile order for inversion recoveryprepared interleaved segmented GRE sequence in delayed enhancement imaging for the assessmentof myocardial viability.

10:45 10:57 (113) Microvascular Obstruction Over Time as a Predictor for Left VentricularRemodelingJose Rodriguez Palomares, MD; Northwestern Memorial Hospital

Time after bolus contrast injection is paramount to determine the “no-reflow” volume. Themicrovascular obstruction volume 10 min after contrast is the strongest predictor for ESV and EFat one year follow-up.

10:57 11:09 (114) The Relationship Between Signal Intensity and Myocardial GadoliniumConcentration for Three MR Perfusion Pulse Sequences: Implications forMeasuring Absolute Myocardial Blood FlowDaniel Lee, MD; Northwestern University Feinberg School of Medicine

The relationship between myocardial signal intensity and gadolinium concentration affects absoluteblood flow calculation. It is linear for inversion recovery steady state free precession but nonlinearfor saturation recovery echo planar imaging and turbo fast low angle shot perfusion sequences.

11:09 11:21 (115) Parallel Acquisition to Improve Temporal Resolution in the Rapid Detectionof Myocardial Infarction: Comparison of Image Quality and ArtifactsAmol Bahekar, MD MPH; Rosalind Franklin University/Chicago Medical School

Current study compares the conventional cardiac MRI images of post myocardial infarct patientswith the images acquired using parallel imaging technique (PAT) by measuring the size, extent ofinfarction and image quality.

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11:21 11:33 (116) Contractility Reserve in Segments Non-Viable on Delayed Enhancement;Analysis with Low Dose Dobutamine MRISharon Kirschbaum, MD; Erasmus MC

Contractility reserve in segments non-viable on delayed enhancement; analysis with low dosedobutamine MRI. This was observed as an increase in segmental wall thickening in segments withTEI<50% and 50%-75% although a higher dose was needed when TEI 50%-75%.

11:33 11:45 (117) Late Gadolinium Enhancement of the Right Ventricle - Is It ReallyDifferent from the Left ?Lars Grosse-Wortmann, MD; The Hospital for Sick Children

The optimal TI for LGE of the RV is believed to be shorter than that of the LV. We hypothesize thata black rim artifact along the myocardium-blood border are misinterpreted as RV myocardium withan only apparently shorter TI.

11:45 11:57 (118) Manganese Guided Cellular MRI Enables Evaluation of Human StromalCell ViabilityMayumi Yamada, MD; Stanford University

Manganese chloride can demonstrate the potential to detect cellular viability and biologicalproperty, hence it can be used as a non invasive biological evaluation of transplanted human stromalcells within injured myocardium.

12:00 12:30 SCMR Business Meeting Los Angeles Room

12:30 13:30 Lunch on Your Own/Poster Viewing Session California Showroom

13:30 15:00 Parallel Session - CLINICALCMR vs. CT for Vascular and Coronary Disease Los Angeles RoomModerators: Frank Rademakers, MD; University Hospitals LeuvenScott Flamm, MD; Cleveland Clinic Cardiovascular Imaging

13:30 13:45 Coronary Angiography by CT - Methods and Clinical ResultsMatthew Budoff, MD, PhD, DMSc; David Geffen School of Medicine, UCLA

13:45 14:00 CT Assessment of the Atherosclerotic PlaqueMilind Desai, MD; Cleveland Clinic

14:00 14:15 MR for Plaque Characterization and QuantificationWon Yong Kim, MD; Skejby University Hospital

14:15 14:30 What to Image? Coronary Arteries vs. Function and IschemiaEike Nagel, MD; King’s College London

14:30 14:45 Panel Discussion: Which Approach for CAD Detection and Risk Stratification?Warren J. Manning, MD; Beth Israel Deaconess Medical CenterDaniel K. Berman, MD; Cedars-Sinai Medical Center

13:30 14:45 Parallel Session - NON-CLINICAL Beverly Hills RoomNew RF Coil Designs for CMRModerators: Thoralf Niendorf, PhD; RWTH AachenTitus Lanz, PhD; Rapid Biomedical

13:30 13:45 Clinical Needs and Requirements for New CMR RF - Coil DesignsTo Be Determined

13:45 14:00 Clinical Value of Many - Element RF - Coil Array Technology in CMRThoralf Niendorf, PhD; RWTH Aachen

14:00 14:15 Potential CMR Applications of Parallel RF - Transmission Coil TechnologyYudong Zhu, PhD; GE Global Research Center

14:15 14:30 The Impact of RF - Coil Technology on Experimental CMR with AnimalModelsGert Klug, MD; University of Klinitz

14:30 14:45 RF - Coil Technology for Non-Proton CMR: Design and ApplicationsJürgen Schneider, PhD; University of Oxford Wellcome Trust Centre for Human Genetics

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13:30 15:00 Parallel Oral Abstract Session IV: CMR Data on Prognosis - Here We Are Santa Monica RoomModerators: W. Gregory Hundley, MD; Wake Forest University Massimo Lombardi, MD; CNR Clinical Physiology Institute

13:33 13:45 (119) Visualized Microinfarction on Contrast Enhanced MR Imaging Linkedto Progressive Left Ventricular DysfunctionMaythem Saeed, DVM, PhD; University of California San Francisco

Discrete microinfarction, visualized on CE-MRI, can be directly linked to LV dysfunction.Additionally, it causes progressive decline in LV function. The observed changes are similar tothat observed in ischemic cardiomyopathy.

13:45 13:57 (120) Assessment of Wall Motion Score Index by DobutamineCardiovascular Magnetic Resonance Predicts Future Cardiac Events inPatients with Mild to Moderate, but not Severe Reduction of LeftVentricular Ejection FractionErica Dall'Armellina, MD; Wake Forest Univeristy School of Medicine

In patients with coronary artery disease and impaired left ventricular ejection fraction (LVEF),dobutamine induced change in wall motion score index shows incremental prognostic value forpredicting cardiac events. This is not true for resting LVEF < 40%.

13:57 14:09 (121) Prognostic Value of Normal Adenosine Stress Cardiac MagneticResonance Imaging Exams - One Year Follow-up Results of aProspective StudyGuenter Pilz, MD; Clinic Agatharied, University of Munich

Normal adenosine stress CMR predicted a very low MACE rate and an excellent one-yearprognosis in 218 patients with suspected CAD. Our results provide clinical reassurance thatpatients at risk for CAD-associated MACE were not missed by adenosine stress CMR.

14:09 14:21 (122) Regional Myocardial Functional Patterns by Quantitative Tagged MagneticResonance Imaging in an Adult Population Free of Cardiovascular RiskFactors: The Multi-Ethnic Study of Atherosclerosis (MESA)Veronica Fernandes, MD, PhD; JHU

To summarize tagging MRI myocardial parameters, and to assess gender differences. Radialstrain was independent of gender and showed increased values from the apex to base. Womenhad greater values of beta angle, rotation and twist when compared to men.

14:21 14:33 (123) Functional Recovery after Acute Myocardial Infarction: A Comparisonbetween Angiography, Electrocardiography and CardiovascularMagnetic Resonance Measures of Microvascular InjuryRobin Nijveldt, MD; VU University Medical Center

LGE MVO is a better prognostic marker than other currently used determinants ofmicrovascular injury. LGE MVO predicts global and regional functional recovery in patientsafter reperfused AMI, beyond infarct transmurality.

14:33 14:45 (124) Delayed-Enhancement MRI as a Predictor of Functional Recovery afterRevascularization: Results from an International Multicenter Viability Trial Veronica Lenge, MD; Baylor College of Medicine

The Multicenter Viability Trial confirmed the prognostic value of DE- MRI for predictingrecovery of left ventricular function recovery after revascularization in patients with chroniccoronary artery disease (CAD).

14:45 14:57 (125) Characterization of Infarct Heterogeneity by Fuzzy ClusteringJay Detsky; Sunnybrook Health Sciences Centre

Inversion-recovery SSFP yields multiple delayed enhancement images at different inversiontimes that have been used to create pixel-by-pixel parameter maps. Fuzzy clustering methodswere developed to use the parameter maps to detect areas of heterogeneous infarct.

15:00 15:30 Refreshment Break/Exhibits California Showroom

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15:30 17:00 Parallel Oral Abstract Session V: Progress in Coronary CMR Imaging Los Angeles RoomModerators: Eike Nagel, MD; King’s College LondonHajime Sakuma, MD; Mie University Hospital

15:33 15:45 (126) Comparison of Coronary MR and CT Angiography in Detection ofCoronary Stenosis with Coronary CalcificationXin Liu, MD; Northwestern University

Diagnostic performance of coronary MRA and CTA for detecting significant stenosis was comparedin 18 patients with high calcium score using conventional angiography as a reference. Receiveroperating characteristic analysis demonstrated coronary MRA has better diagnostic performance thancoronary CTA.

15:45 15:57 (127) Coronary Wall MRI Detects Subclinical Atherosclerosis in AsymptomaticIndividuals in the Multi-Ethnic Study of Atherosclerosis (MESA)Robson Macedo, MD; Johns Hopkins University|School Of Medicine

Coronary wall MRI was used to measure atherosclerotic disease burden in individuals without clinicalcardiovascular disease. MRI detected increased coronary wall thickness in individuals withsubclinical markers of atherosclerotic disease and in individuals with zero coronary calcium score.

15:57 16:09 (128) Head-to-head Comparison of Whole-Heart Coronary MR and 40/64 SliceMultidetector-CT Angiography for Detection of Coronary Artery StenosisBernhard Gerber, MD; Cliniques Universitaires St.Luc

MDCT had higher success rate and higher diagnostic accuracy than WH-MRCA on intention todiagnose basis. However, the diagnostic accuracy of WH-MRCA on per-segment and per-vessel basiswas not statistically different from MDCT if only interpretable segments were considered.

16:09 16:21 (129) Whole Heart Coronary MR Angiography Acquired with 32- ChannelCardiac Coils for the Detection of Coronary Artery DiseaseMotonori Nagata; Mie University Hospital

Use of 32 channel coils allows for acquisition of whole heart coronary MRA in a reduced imagingtime and with high study success rate, which resulted in considerably improved overall detection rateof CAD in subjects who underwent coronary MRA.

16:21 16:33 (130) Contrast-enhanced Whole-Heart Coronary MR Angiography at 3.0 T:Comparison to Steady-State Free Precession Technique at 1.5 T Xin Liu, MD; Northwestern University

A comparison of state-of-the-art 1.5T and 3T whole heart coronary MRA techniques in 10 volunteersdemonstrated higher CNR, shorter acquisition-time, and better depiction of coronary segments forContrast-enhanced slow-infusion 3D-FLASH at 3.0 T compared to non-contrast SSFP at 1.5 T.

16:33 16:45 (131) Arterial Spin Labeled Myocardial Perfusion Imaging with BackgroundSuppression: Initial ResultsZungho Zun, MS; University of Southern California

We investigate the feasibility of myocardial perfusion imaging using arterial spin labeling withbackground suppression. Preliminary in-vivo results demonstrate the suppression of blood andmyocardial signal to <0.7% of their equilibrium values.

16:45 16:57 (132) Coronary Vessel Wall Evaluation by MRI in the Multi-Ethnic Study ofAtherosclerosis (MESA): Physiologic Determinants of Image QualityAshkan Malayeri, MD; Johns Hopkins Hospital

Purpose of this study was to evaluate the role of physiologic parameters in coronary vessel wallimaging. Improved depiction of the coronary artery wall is related to coronary rest period,atherosclerotic plaque burden and inversely related to heart rate.

15:30 17:00 Parallel Oral Abstract Session VI: Beverly Hills RoomToward a Better Understanding of Cardiovascular RiskModerators: Gerald M. Pohost, MD; USCDebiao Li, PhD; Northwestern University

15:45 15:57 (133) Obesity Is Associated With Decreased Myocardial Contraction FractionDespite Preserved Ejection FractionMichael Chuang, MD; Beth Israel Deaconess Medical Center

Obesity may be associated with changes in cardiac structure and function. We found that evenamong subjects with normal (>60%) ejection fraction, myocardial contraction fraction, ageometry- independent volumetric measure of myocardial performance, is depressed in obeseversus lean subjects.

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15:57 16:09 (134) Metabolic Imaging of the Aging Heart: Myocardial TriglycerideContent as Independent Predictor of Diastolic FunctionRutger vd Meer, MD; Leiden University Medical Center

In the physiologically aging heart, myocardial triglyceride content increases and contributessignificantly to the age-related decline in left ventricular diastolic function, independent of bodymass index, blood pressure, and biochemical blood markers.

16:09 16:21 (135) Influence of Short-Term Excessive Dietary Fat Intake on MyocardialTriglyceride Content and FunctionRutger vd Meer, MD; Leiden University Medical Center

Short term high dietary fat content has no influence on myocardial triglycerideaccumulation or myocardial function, despite marked changes in plasma triglycerides andfree fatty acids. However, hepatic triglyceride content was significantly elevated after thehigh fat diet.

16:21 16:33 (136) Left Ventricular Mass and Dimensions: Determining the MostAppropriate Index to Account for Body Size using MRISaul Myerson, MD MRCP FESC; University of Oxford

Lean body mass was the best index for LV mass and dimensions. Body surface area did nothave a linear relationship, did not remove the effect of body size and should be questioned.Linear dimensions had no appropriate indices.

16:33 16:45 (137) Ventricular Hypertrophy Precedes Ventricular Cavity Dilatation inResponse to Increasing Body Mass Index.Oliver Rider; University of Oxford

Left and right ventricular hypertophy precede ventricular cavity dilatation in response toincreasing Body Mass Index. Elevated leptin levels may be responsible for this early effect ofventricular mass.

16:45 16:57 (138) Determination of Myocardial OEF with a CMR Method in a StenoticDog StudyKyle McCommis, BS; Mallinckrodt Institute of Radiology, Washington University School of Medicine

The impact of myocardial blood volume determination to a CMR method was evaluatedin the estimation of myocardial OEF during hyperemia in a canine stenosis model. Theeffect of blood volume is subtle and regional myocardial OEF can be detected.

15:30 17:00 Parallel Oral Abstract Session VII: New Methods: The Cutting Edge Santa Monica RoomModerators: Peter Kellman, PhD; NIHHildo Lamb, MD, PhD; Leiden University Medical Center

15:33 15:45 (139) Relationship Between Coronary Calcification and EndotheliumDependent Coronary Vaso-reactivity in Asymptomatic DiabeticPatients Without Overt Coronary Artery DiseaseM. Khalid, MD; New York Hospital

Endothelium-dependent perfusion reserve(MPR), as a marker for coronary vaso-reactivity,is impaired in coronary arteries with any amount of calcification. MPR was calculated bymeasuring myocardial blood flow during rest and during immersion for 1 minute in cold-water by Cardiac MRI.

15:45 15:57 (140) Molecular MRI of Vascular Remodeling in a Swine Model of CoronaryInjury using an Elastin-Binding Contrast AgentRené Botnar, PhD; King’s College London

We sought to demonstrate the feasibility of imaging vascular remodeling in a porcine modelof coronary injury using BMS753951, a novel elastin-binding low molecular weight contrastagent.

15:57 16:09 (141) Volumetric Cardiac Quantification Using Three Dimensional DualPhase Whole Heart MRISergio Uribe Arancibia, MSc; King's College London, Division of Imaging Sciences

16:09 16:21 (142) Quantification of Left Ventricular Internal Flow from Cardiac MagneticResonance Images in Patients with Dyssynchronous Heart FailureBrandon Fornwalt, BS; Emory/Georgia Institute of Technology

We developed methodology that utilizes cardiac magnetic resonance images to quantifyinternal flow in the left ventricle that results from dyssynchronous motion of the ventricularwalls. Internal flow was significantly different between patients with dyssynchronous heartfailure and normal controls.

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16:21 16:33 (143) Multidimensional Turbulence Mapping in Mitral InsufficiencyJohn-Peder Kvitting, MD PhD; Linköping University Hospital

Generalizing phase-contrast MRI to map the effects of turbulence in the setting of mitralinsufficiency. Novel data are presented on the relationship between flow regurgitation and areasof turbulent flow.

16:33 16:45 (144) Prospective Self-Gating for Simultaneous Compensation of Cardiacand Respiratory MotionJelena Curcic; Institute for Biomedical Engineering ETH Zürich

A prospective self-gated approach for cardiac imaging was successfully implemented andevaluated. Cardiac and respiratory related signal variations were accurately detected in real-time from the repeatedly acquired k-space center. The image quality obtained is comparable toretrospective and ECG-triggered approaches.

16:45 16:57 (145) Cardiac Magnetic Resonance Based Assessment of Cardiac Work byPressure-Volume and Stress-length Relation in Patients with DilatedCardiomyopathy and Aortic Valve StenosisPeter Alter, MD; Philipps University

CMR based pressure-volume and stress-length relations allow to assess cardiac work.Myocardial work was reduced in patients with DCM and also in AS, while stroke work wasreduced in DCM only, which is suggested to be relevant for the prognosis.

17:00 18:30 Parallel Session - CASES TO LEARN FROM Los Angeles RoomModerators: Frank Rademakers, MD; University Hospitals LeuvenRossella Fattori, MD; Azienda Ospedaliera S. Orsola-Malpighi

Panel: Ricardo Cury, MD; Massachusetts General Hospital and Harvard Medical SchoolSaul Myerson, MD; John Radcliffe HospitalJeanette Schulz-Menger, MD; Franz-Volhard-Klinik, Charite Universitätsmedizin BerlinEdward T. Martin, MD; Oklahoma Heart InstituteAlbert van Rossum, MD; VU Medical CenterRobert S. Biederman, MD; Allegheny General Hospital

17:00 18:30 Parallel Oral Abstract Session VIII: New Methods Using New Hardware and Software Beverly Hills RoomModerators: Victor Ferrari, MD; University of Pennsylvania Medical CenterMatthias Gutberlet, MD; University Leipzig

17:03 17:15 (146) Improved 3D SPACE Carotid Vessel Wall Imaging at 3.0TZhaoyang Fan, MSc; Northwestern University

Motion-sensitive dephasing preparation was combined with SPACE to improve dark-bloodefficiency in carotid vessel wall imaging at 3.0T. The increased wall-lumen CNR (66%) a n disotropic submillimeter resolution from SPACE make this new sequence a promising techniquefor plaque screening.

17:15 17:27 (147) 31P Cardiac Spectroscopy at 3T: T1 quantificationAbdel-Monem El-Sharkawy; Johns Hopkins University

A custom coil and protocol for human cardiac 3T 31P MRS is used to measure the T1s of PCrand Á-ATP in the human heart via saturation recovery, and a new, efficient dual-TR approachthat reduces bandwidth and power requirements.

17:27 17:39 (148) TPAT Accelerated Myocardial Tagging with a 32-Channel CoilNeil Isaac; University of Pennsylvania Medical Center

TPAT accelerated cine imaging with myocardial tagging performed using a 32-channel coilallows increased tag density with improved spatial resolution and image quality at no loss oftemporal resolution. This may be of use for evaluation of RV regional function.

17:39 17:51 (149) Multi Slice Wide Band SSFP CINE for Routine 3T Cardiac ImagingAjit Shankaranarayanan; GE Healthcare

The gated wide band ssfp sequence has been adapted to perform multi slice cine imaging.Results from the wbSSFP cine sequence has been compared to the conventional SSFP imageswith identical parameters.

17:51 18:03 (150) Myocardial Signal Behaviors of Balanced SSFP Imaging at 3TKyunghyun Sung, MS; Department of Electrical Engineering, University of Southern California

The appearance of myocardium in balanced SSFP images is influenced by imperfect sliceprofiles, off-resonance, and flip angle variation. We demonstrate accurate myocardial signalprediction using models that consider these three practical factors.

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18:03 18:15 (151) Myocardial Blood Flow Estimation Using a Model-IndependentDeconvolution Method at 3T MRI: Comparison to 13N-ammonia PETNathan Pack; Department of Radiology, University of Utah

A model-independent deconvolution analysis method that uses iterative minimizationand a temporal smoothness constraint was used to compute blood flow estimates from3T MR images. Myocardial blood flow measured using dynamic 13N-Ammonia PETgave similar results.

18:15 18:27 (152) Gadolinium-labeled Liposomes as a DENSE-Compatible, Positive MRIContrast Agent for Serially Assessing Macrophage Activity and RegionalContractile Function in the Murine Heart after Myocardial InfarctionBrent A. French, PhD; University of Virginia

A new multimodal, multilamellar liposomal contrast agent labeled with both Gd-DTPA and afluorescent tag is described that provides for serial macrophage tracking after myocardialinfarction and, unlike iron-based agents, is compatible with cine DENSE analysis of regionalcontractile function.

17:00 18:30 Parallel Oral Abstract Session IX: New Vascular Applications Santa Monica RoomModerators: Joachim Lotz, MD; Hannover Medical SchoolJohn Grizzard, MD; VCU Medical Center

17:03 17:15 (153) MR Vessel Wall Imaging of the Descending Aorta Using an Elastin-Binding Contrast Agent in an ApoE TNFalpha Double KnockoutMouse Model of Advanced AtherosclerosisAntti Saraste; Klinikum rechts der Isar

Delayed-enhancement MRI demonstrated focal uptake of a novel gadolinium-based elastin-binding contrast agent in the atherosclerotic abdominal aorta of ApoE-/- TF¢ct mice with littleuptake in the non-stenotic suprarenal vessel segments.

17:15 17:27 (154) Aortic Pulse Wave Velocity Assessed with Velocity-Encoded MRI: A Validation and Reproducibility StudyHeynric Grotenhuis, MD; Leiden University Medical Center

Aortic Pulse Wave Velocity assessed with MRI is validated by invasive pressure measurementsduring catheterization. Reproducibility of the MRI method is tested and compared tophysiological variation.

17:27 17:39 (155) Quantification of Pulse Wave Velocity in the Pulmonary Artery inPatients with Pulmonary HypertensionJavier Sanz, MD; Mount Sinai School of Medicine

In 94 patients with known or suspected pulmonary hypertension (PH), pulmonary pulse wavevelocity (PWV) was calculated from same-day right heart catheterization and phase-contrastimaging. PWV was markedly increased in patients with PH and correlated strongly with PH severity.

17:39 17:51 (156) Pulmonary Vein Imaging by 3D Non-Contrast, Free Breathing SSFPMR Angiography; A Novel TechniqueAparna Singhal; UCLA

Our aim was to investigate the feasibility of non-contrast, free breathing 3D-SSFP MRAngiography for pulmonary veins evaluation and to correlate with contrast-enhanced MRA.3D-SSFP MRA provides sufficient vascular definition and SNR and CNR for confidentevaluation of pulmonary veins.

17:51 18:03 (157) Renal Artery Stenosis: Independent Predictor of Increased Mortalityin Patients with Heart Failure. A Magnetic Resonance Imaging StudyChristos Bourantas; Hull University

Renal artery stenosis: an independent predictor of increased mortality in patients with heartfailure who are on stable medical treatment with b-blockers and ACE inhibitors.

18:03 18:15 (158) A Contrast Dose Reduction Study for 3D High Spatial ResolutionContrast-Enhanced Magnetic Resonance Angiography of Supra-aorticArteries at 3.0 TeslaAnderanik Tomasian; UCLA

Three-dimensional high-spatial-resolution contrast-enhanced MRA of supra-aortic arteries at3.0T can be performed with a gadolinium dose as low as 0.05 mmol/kg, without compromisingimage quality.Adoption of low-dose protocols should diminish sensitivity to dose-dependentcomplications and result in substantial cost savings.

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18:15 18:27 (159) 3D Submillimeter Isotropic Resolution Superficial Femoral Artery WallMRI Using SPACE at 3.0TZhuoli Zhang; Northeastern University

SPACE images showed plaque in any angle which is not capable of being accomplished with 2DTSE. With more time efficient as compared to 2D TSE, SPACE allows an adequate spatial coverageof superficial femoral artery with a high resolution.

17:30 18:30 Moderated Poster Session – Clinical California ShowroomModerators: Robert S. Biederman, MD; Allegheny General HospitalCarlos Rochitte, MD; University of Sao Paulo Medical School*Please see the full listing of moderated poster sessions located on page 31*

17:30 18:30 Poster Session I – Presenters Present/Exhibits California ShowroomWine and Cheese Reception

19:00 User Meetings

Saturday, February 2, 20087:00 8:00 Continental Breakfast/Exhibits California Showroom

7:00 8:00 Coffee with the Experts I: What We Do in Acute Beverly Hills RoomCoronary Syndrome, Aortic Dissection, Asymptomatic CAD, RV DilatationAcute Coronary Syndrome - James White, MD; London Health Sciences CentreAortic Dissection - Joerg Barkhausen, MD; University HospitalAsymptomatic CAD - Patricia Bandettini, MD; NIH/NHLBICoronary Angiography - Hajime Sakuma, MD; Mie University Hospital

8:00 9:30 Parallel Session - CLINICAL CMR in Non-Ischemic CMP Los Angeles RoomModerators: Sanjay Prasad, MD; Royal Brompton HospitalMatthias G. Friedrich, MD; Stephenson CMR Centre, University of Calgary

8:00 8:15 Assessment of RV Myocardial Fat and Fibrosis in Non-Ischemic CMPJames W. Goldfarb, PhD; St Francis Hospital

8:15 8:30 Microvascular Dysfunction in Non-Ischemic CMPSteffen Petersen, PhD; John Radcliffe Hospital

8:30 8:45 The Potential of Chemical Shift Imaging for Non-Ischemic CMPFrank Kober; Centre de Resonance Magnetique Biologique et Medicale

8:45 9:00 Assessment of Wall Structure and Function in HCMWen-Yih Tseng, MD, PhD; National Taiwan Univeristy - College of Medicine

9:00 9:15 The Change of Tissue Characteristics in the Course of MyocarditisRavi G. Assomull, MRCP; Royal Brompton Hospital

9:15 9:30 Discussion

8:00 9:30 Parallel Session - NON-CLINICAL Parallel Imaging Beverly Hills RoomModerators: Sebastian Kozerke, PhD; Institute for Biomedical Engineering University and ETH ZurichKrishna Nayak, PhD; University of Southern California

8:00 8:15 Dynamic Parallel Imaging Methods for Cardiac MRJeffrey Tsao, PhD; Novartis Institutes for BioMedical Research, Inc.

8:15 8:30 Cardiac Surface Coil Arrays for Parallel ImagingSebastian Kozerke, PhD; Institute for Biomedical Engineering University and ETH Zurich

8:30 8:45 Applications: Function and FlowVivek Muthurangu, MD; University College London

8:45 9:00 Applications: Perfusion and Delayed EnhancementPeter Kellman, PhD; NIH

9:00 9:15 Applications: AngiographyGerhard Laub, PhD; Siemens Medical Systems

9:15 9:30 Discussion

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8:00 9:30 Parallel Session - CONGENITALCMR of Tetralogy of Fallot Santa Monica RoomModerators: Mark Fogel, MD; Children's Hospital of PhiladelphiaKaren Ordovas, MD; University of California San Francisco

8:00 8:15 Pre-Operative Evaluation of Unrepaired Tetralogy of FallotPhilipp Beerbaum, MD; King's College London

8:15 8:30 Post-Operative Evaluation of Tetralogy of FallotKaren Ordovas, MD; University of California San Francisco

8:30 8:45 Evaluation of Diastolic Function in Repaired Tetralogy of FallotWillem Helbing, MD; Erasmus Medical Center - Sophia Children's Hospital

8:45 9:00 Surgical Pulmonary Valve Replacement in Tetralogy of Fallot: Lessons from CMRAlexander van Straten, MD; Leiden University Medical Center

9:00 9:15 Transcatheter Pulmonary Valve Replacement: Lessons from CMRAndrew Taylor, MD; Centre for Cardiovascular MR

9:15 9:30 Discussion

9:30 10:15 CMR Technology Updates Los Angeles RoomModerators: Stefan Neubauer, MD; John Radciffe HospitalCharles B. Higgins, MD; UCSF Medical Center

10:15 10:55 CMR Questionnaire Los Angeles RoomGerald M. Pohost, MD; USC

10:55 11:15 Refreshment Break/Exhibits California Showroom

11:15 12:45 Parallel Oral Abstract Session X: CMR of Non-Ischemic Heart Disease I Los Angeles RoomModerator: James White, MD; London Health Sciences Centre

11:18 11:30 (200) Cardiac Magnetic Resonance Implicates that Amyloidosis,Hypertension Induced Left Ventricular Hypertrophy, HypertrophicObstructive and Hypertrophic Non Obstructive Cardiomyopathy Sharethe Same Pattern of Non Concentric Left Ventricular RemodelingTim Schäufele, MD; University Hospital Heidelberg

CMR data suggest that direct comparison of LV wall thickness can rule out the existence of thecommonly accepted idea of a symmetric Remodeling pattern in patients with LV hypertrophy.

11:30 11:42 (201) Can Cardiovascular MRI be used as a Definitive Test to CharacterizeCardiac Masses Initially Identified Using Echocardiography?Anna Czajka, MD; Allegheny General Hospital/University of Pittsburgh Medical Center

The comparison of echocardiography and cardiac magnetic resonance in their ability tocharacterize and diagnose cardiac and paracardiac masses suggests that magnetic resonanceshould be an essential non-invasive test in all cases of suspected cardiac mass whenechocardiography is inconclusive.

11:42 11:54 (202) Contrast-Enhanced MRI for High Yield Detection of Left VentricularThrombus - Predictors of Improved Thrombus Detection versusEchocardiographyJonathan Weinsaft; Weill Medical College of Cornell University

Among a broad at-risk patient cohort, contrast-enhanced MRI provided improved leftventricular thrombus detection versus contrast and non-contrast echocardiography. Leftventricular thrombus is typically detected by contrast-enhanced MRI but missed byechocardiography when mural in shape or small in volume.

11:54 12:06 (203) Correlation of Myocardial T2* and T2 Measurements in ThalassemiaPatientsTaigang He, PhD; Royal Brompton Hospital and Imperial College London

This original study demonstrated that myocardial T2* correlated linearly with T2measurements in patients with iron overload, which suggests that both T2* and T2 can be usedfor the reliable assessment of iron overload in the heart.

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12:06 12:18 (204) Magnetic Resonance Imaging Findings in Early Arrhythmogenic RightVentricular DysplasiaAditya Jain, MBBS, MPH; Johns Hopkins University

Dyssynchronous contraction of the RV basal free wall was frequently seen on MR imaging in patientswith early ARVD. This finding may represent earliest phenotypic expression of ARVD on MR Imaging.

12:18 12:30 (205) Late Enhancement in Contrast-Enhanced Cardiac MRI Facilitates theCharacterization of Different Etiologies in Non-Ischemic Myocardial DiseasePeter Hunold, MD; University Hospital Essen

Late gadolinium enhancement (LGE) in contrast-enhanced cardiac MRI is helpful in the assessmentof non-ischemic myocardial disease through both differentiating from ischemic disease and facilitatingthe differential diagnosis of non-ischemic etiologies. Each myocardial disease MRI study shouldcontain LGE imaging.

12:30 12:45 (206) Characteristics of Surgically Confirmed Constrictive Pericarditis byMagnetic Resonance ImagingSarah Hussain; The Cleveland Clinic

Patients with surgically proven constrictive pericarditis have at least 3 of 5 characteristic findings on MRI:pericardial tethering; pericardial thickening/ calcification; tubular/conical deformity of a ventricle;abnormal diastolic septal motion; and diastolic restraint of the ventricles.

11:15 12:45 Parallel Oral Abstract Session XI: In Real Time: Interventions and More Beverly Hills RoomModerators: Robert Lederman, MD; National Heart, Lung and Blood InstituteReza Razavi, MD; King's College London

11:18 11:30 (207) Molecular MR-Imaging of Myocardium using EP-3600, a Collagen SpecificContrast Agent: Assessment of Myocardial Perfusion Defects in a Swine ModelElmar Spuentrup, MD; University of Cologne

Initial results of molecular MR-imaging of myocardial perfusion using a collagen-specific contrastagent are presented. This new agent enables prolonged, high contrast and high spatial resolutionvisualization of myocardial perfusion defects in a swine model of coronary stenosis.

11:30 11:42 (208) Fusion of MR-Derived Anatomical and Late Enhancement Image Data withAblation Mapping for Verification of Lesion Delivery for Cardiac Radio-Frequency AblationBenjamin Knowles; King's College London

We have developed a technique to fuse ablation lesions and cardiac anatomy from MRI with ablationmaps from an electro-anatomical mapping system. We present the fused data results for a patientundergoing treatment for atrial flutter in the XMR setting.

11:42 11:54 (209) MRI Cardiac Catheter Assessment of Total and Differential PulmonaryVascular Resistance in the Context of Single Ventricle PhysiologyAaron Bell, MB.ChB, MRCPCH; King’s College London

MRI Cardiac Catheter allows for the measurement of pulmonary vascular resistance in patients withcomplex congenital heart disease. Differential pulmonary vascular resistance can be measured whenthere are multiple sources of pulmonary blood flow.

11:54 12:06 (210) Validation of a Semi-Automatic Coronary Vessel Tracker Algorithm forMagnetic Resonance Whole-Heart AngiographyJeroen Sonnemans; Philips Medical Systems

We developed an algorithm for semi-automatic tracking of coronary arteries in MR whole-heart imagesand demonstrate the algorithm tracks the coronary CVA with an equal or higher accuracy whencompared to a skilled user using manual path tracking tools.

12:06 12:18 (211) MRI of Coronary Vessel Wall Injury in a Swine Model of CoronaryIntervention Using an Electrostatically Stabilized VSOP NanoparticleRené Botnar; PhD, King’s College London

We demonstrate the combined use of a matrix specific Gd-based contrast agent (BMS753951)together with an iron oxide nanoparticle for exclusive visualization of the pathologically alteredcoronary vessel wall.

12:18 12:30 (212) Material Point Tracking with Enforced Incompressibility Using MRIScott Lipnick; University of California, Los Angeles

Implementation of tissue tracking algorithm based on enforcing incompressibility of tissue trajectoriesfrom PC-MRI and DENSE-MRI. Myocardial incompressibility is enforced through minimizing thedivergence of the instantaneous velocity.

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12:30 12:42 (213) Optimally Undersampled Variable Density Spiral TrajectoriesApplied to Real-time Cardiac MRI at 3 TeslaYoon-Chul Kim, MS; University of Southern California

Variable-density spirals can be optimized for incoherence of spatial aliasing artifacts, anditerative reconstruction from optimally undersampled data produces images withsubstantially reduced aliasing. This technique is applied to real-time cardiac MRI at 3-Tesla,and is compared with uniform-density spirals.

11:15 12:45 Parallel Oral Abstract Session XII: What is New in Congenital CMR? Santa Monica RoomModerators: Albert de Roos, MD, PhD; Leiden University Medical CenterDavid Patton, MD; Alberta Children's Hospital

11:18 11:30 (214) RV Free Wall Tagging for the Assessment of RV MyocardialFunction in Congenital Heart DiseaseSylvia Chen, MBBS; Royal Brompton Hospital

RV volume measurements for serial comparison in congenital heart are time consuming anddifficult. Here we present initial results of automated analysis of tagged CMR measurements ofthe systolic displacements of myocardium in the basal free wall of the RV.

11:30 11:42 (215) Reduced Aortic Elasticity and Dilatation are Associated with AorticRegurgitation and Left Ventricular Dysfunction After the ArterialSwitch OperationHeynric Grotenhuis, MD; Leiden University Medical Center

Aortic root dilatation and reduced elasticity of the proximal aorta are frequently present inpatients after the arterial switch operation, and are associated with aortic regurgitation,increased LV dimensions and LV systolic dysfunction.

11:42 11:54 (216) Beyond Late Gadolinium Enhancement: Ventricular Dysfunction in Adults with Congenital Heart Disease is Associated with DiffuseMyocardial Fibrosis as shown by the Volume of Distribution of GadoliniumCraig Broberg; Oregon Health and Science University

Using the volume of distribution of gadolinium, we show evidence of diffuse fibrosis relatedto ventricular dysfunction in congenital heart disease.

11:54 12:06 (217) Normal Human Ventricular Volume and Mass Values in ChildrenAges 5- 10 Years Using Steady State Free Precession MRIWilliam Gottliebson, MD MS; Cincinnati Childrens Hospital and Medical Center

Normal cardiac MRI values for volumes and ventricular mass are presented for subjects aged5 - 10 years.

12:06 12:18 (218) A Cardiovascular MRI Derived Energy Model Reliably DifferentiatesSevere Idiopathic Pulmonary Hypertension from SecondaryPulmonary HypertensionVikas Rathi, MD; Allegheny General Hospital

Cardiac energy use by the failing right ventricle in pulmonary hypertension can distinguishvarious classes of pulmonary hypertension patients.

12:18 12:30 (219) Feasibility of Whole-Heart Steady-State Free Precession MagneticResonance Coronary Angiography (MRCA) in Infants and Childrenwith Congenital Heart DiseaseTarinee Tangcharoen, MD; King's College London

The use of an optimized three dimensional (3D) whole-heart Steady-State FreePrecession Magnetic Resonance Coronary Angiography (MRCA) imaging sequence forassessment of the coronary artery system in children with congenital heart disease isproposed.

12:30 12:42 (220) Simultaneous Measurement of Three Dimensional (3D) Left AndRight Ventricular Volumes and Ejection Fraction DuringDobutamine Cardiovascular Magnetic ResonanceSangeeta Mandapaka, MD; Wake Forest University

Simultaneous change in RV and LV stroke volume can be assessed in a highly reproduciblemanner throughout the course of pharmacologic stress administered to achieve 85% ofMPHRR for age.

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12:45 13:45 Moderated Poster Session – Experimental California ShowroomModerators: Nael Osman, PhD; Johns Hopkins University Hildo Lamb, MD, PhD; Leiden University Medical Center*Please see the full listing of moderated poster sessions located on page 31*

12:45 13:45 Lunch on Your Own/Poster Session II/Exhibits California ShowroomPresenters Present

13:45 15:15 Parallel Session - CLINICAL Los Angeles RoomNew Diagnostic Targets in Myocardial InfarctionModerators: Raymond Kwong, MD; Brigham and Women's HospitalBernhard Gerber, MD; Cliniques St. Luc UCL

13:45 14:00 Infarct ResorptionHakan Arheden, MD, PhD; Lund University Hospital

14:00 14:15 The Peri-Infarct Zone: Prediction of ArrhythmiaAndre Schmidt, MD, Card; Medical School of Ribeirao Preto

14:15 14:30 Update on the Prognostic Value of Late EnhancementRaymond Kwong, MD; Brigham and Women's Hospital

14:30 14:45 Angiographic Score and Late Enhancement to Estimate SalvageableMyocardiumEdwin Wu, MD; Northwestern University

14:45 15:00 T2 Weighted and Gd-Enhanced CMR for Estimating Area at Risk andInfarct SizeAndrew Arai, MD; NHI / NHLBI

15:00 15:15 Comparison of CMR vs. CTBernhard Gerber, MD; Cliniques St. Luc UCL

13:45 15:15 Parallel Session - NON-CLINICAL Beverly Hills RoomMolecular Imaging: Contrast Agent Mechanisms and CMR ApplicationsModerators: Rene Botnar, MD, PhD; King's College LondonBrent A. French, PhD; University of Virginia

13:45 14:00 Vascular Imaging with MR/Optical Molecular Contrast AgentsDavid Sosnovik, MD; Center For Molecular Imaging Research

14:00 14:15 Molecular Imaging in Ischemic Heart DiseaseFred Epstein, PhD; University of Virginia

14:15 14:30 Plaque Imaging: Comparison of MR, PET and CTVictor Ferrari, MD; University of Pennsylvania Medical Center

14:30 14:45 Gd-Labeled Nanoparticles for Molecular MRISamuel Wickline, MD, PhD; Washington University School of Medicine

14:45 15:00 Cardiac SpectroscopyRobert Weiss, PhD; Johns Hopkins Hospital

15:00 15:15 Fluorine Imaging: An Alternative Approach to Molecular MRISamuel Wickline, MD, PhD; Washington University School of Medicine

13:45 15:15 Parallel Oral Abstract Session XIII: CMR of Non-Ischemic Heart Disease II Santa Monica RoomModerators: Jeanette Schulz-Menger, MD; Franz-Volhard-Klinik, Charite Universitätsmedizin BerlinJames Moon, MD; The Heart Hospital London

13:48 14:00 (221) Comparison of Aortic Valve Area Measured by Cardiac MRI and Dual-Source CTMarkus Jochims; Elisabeth Hospital

Compared to CMR, DSCT with tube current modulation provides another accurate imagingtechnique for the assessment of aortic valve area.

14:00 14:12 (222) Cardiac Magnetic Resonance Assessment of Induced MyocardialInfarction and Reverse Remodeling Early After Alcohol Septal AblationKamaldeep Chawla, MD, DNB Card.; Institute Cardiovasculaire Paris Sud

MRI is used to delineate the extent of acute myocardial infarction in CAD, but its role afterethanol induced septal infarction has not been largely assessed. We report this evaluation inpatients with symptomatic hypertrophic obstructive cardiomyopathy using CE MRI.

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14:12 14:24 (223) Adverse Functional Significance of Delayed Enhancement on CardiacMRI in Primary Systemic AmyloidosisRaymond Migrino, MD; Medical College of Wisconsin

The functional significance of delayed enhancement in primary systemic amyloidosis is notdefined. We found amyloid patients with delayed enhancement on MRI have significant diastolicdysfunction compared to those without.

14:24 14:36 (224) Myocarditis: Relation Between Myocardial Edema and Myocardial MassDuring the Acute and Convalescent Phase. Insights from CMRAnja Zagrosek, MD; Franz-Volhard-Clinic, Charité-Campus Buch, Helios-Klinikum, Humboldt-University

In patients with myocarditis, myocardial edema and LV-mass were assessed by CMR acutely andafter 9 months. The findings suggest that myocardial edema is reflected by a reversible increasein LV-mass and by high signal intensity in T2-weighted imaging.

14:36 14:48 (225) Cardiac MRI for Differential Diagnosis of the Apical BallooningSyndrome - A Series of 46 PatientsIngo Eitel, MD; Heart Center University Leipzig

ABS is a phenomenon mimicking ACS which has a prevalence of approximately 1% in our patientseries. MRI is a useful technique to identify patients with suspected ABS and allows differentiatingABS from other rare causes with unobstructed coronary vessels.

14:48 15:00 (226) Myocardial Fibrosis, Wall Thickness, and Microvascular Perfusion in Hypertrophic Cardiomyopathy. A Cardiovascular MagneticResonance StudyRory O'Hanlon, MRCPI; Royal Brompton Unit

This study suggests that areas of maximal hypertrophy in HCM are at greater ischaemic risk anddevelop greater degrees of fibrosis, possibly due to microvascular ischaemia.

15:00 15:12 (227) Early Detection of Systolic and Diastolic Dysfunction in AsymptomaticHypertrophic Cardiomyopathy Mutation Carriers using CardiacMagnetic Resonance ImagingTjeerd Germans; VU University Medical Center

Systolic and diastolic dysfunction and subsequent left atrial dilation are present in hypertrophiccardiomyopathy mutation carriers before the development of overt hypertrophy. Asymmetricwall thickening is associated with crypt formation with occurs in 82 percent of hypertrophiccardiomyopathy mutation carriers.

15:15 15:45 Refreshment Break/Exhibits California Showroom

15:45 16:45 Parallel Session - POLITICAL Los Angeles RoomNew Codes and New Safety ConcernsModerators: Anthony Fuisz, MD; Washington Hospital CenterSteven Wolff, MD, PhD; Advanced Cardiovascular Imaging

15:45 16:15 New Codes in CMREdward Martin, MD; Oklahoma Heart Institute

16:15 16:45 The Potential Legal Exposure of Using Off-Label Gadolinium with the Risk of NSF

15:45 17:15 Parallel Session - CONGENITAL Beverly Hills RoomCHD - Indications and Imaging ProtocolsModerators: Andrew Powell, MD; Children's Hospital BostonCharles B. Higgins, MD; UCSF Medical Center

15:45 16:00 Pediatric Primary Cardiac TumorsRebecca Beroukhim, MD; Children's Hospital Boston

16:00 16:15 Status-Post Atrial Switch OperationSonya Babu-Narayan, MB, BS, BSc, MRCP; Royal Brompton Hospital London

16:15 16:30 Connective Tissue DisordersWilliam Gottliebson, MD; Cincinnati Children's Hospital Medical Center

16:30 16:45 Heterotaxy SyndromeRajesh Krishnamurty, MD; Texas Children’s Hospital

16:45 17:00 Indications for CT Rather Than CMRHyun Woo Goo, MD; University of Ulsan College of Medicine

17:00 17:15 Discussion

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15:45 17:15 Parallel Oral Abstract Session XIV: Refined Phenotyping by CMR Santa Monica RoomModerator: Fred Epstein, PhD; University of Virginia

15:48 16:00 (228) Functional Cardiac Phenotyping of Vasoactive Intestinal Peptide (VIP)Deficient Mice by MR MicroscopyS. David Smith, PhD; Brookhaven National Laboratory

We quantified ventricular volumes from Cardiac CINE MR images to phenotype the cardiacfunctional capacity in Vasoactive Intestinal Peptide deficient (VIP-/-) mice known to developpulmonary artery hypertension. Pronounced RV dilation was observed in VIP-/- mice whencompared to controls

16:00 16:12 (229) Four Dimensional Velocity Field Reconstruction from PC MRI UsingAdaptive Divergence Free Radial Basis FunctionsKartik Sundareswaran, MS; Georgia Institute of Technology

In this paper, a new method for velocity field reconstruction is presented that utilizes blood flowincompressibility as a property for estimating a continuous flow field representation from a stackof contiguous PC MRI.

16:12 16:24 (230) Manganese Guided Cellular MRI of Human Embryonic Stem Cell ViabilityMayumi Yamada, MD; Stanford University

Manganese may enable precise in vivo MRI of the biological properties of transplanted humanembryonic stem cells.

16:24 16:36 (231) Alternation of Myocardial Oxygen Consumption during Hyperemia:Detection with a CMR MethodKyle McCommis, BS; Mallinckrodt Institute of Radiology, Washington University School of Medicine

A quantitative CMR method is introduced to detect changes in myocardial MVO2 duringhyperemia in a canine stenosis model. While severe stenosis attenuated MVO2 increase in thestenosis subtended region, the remote region also showed reduced increase in MVO2.

16:36 16:48 (232) Real-Time and Gated MR DopplerJuan Santos; Stanford University

To improve intracardiac flow velocity evaluation using a real-time MR Doppler system, wepresent a cardiac gated CINE implementation resulting in higher velocity resolution and range.

16:48 17:00 (233) Evidence that Post-Contrast Delayed Enhancement Identified byCardiovascular Magnetic Resonance is an Arrhythmogenic Substrate inHypertrophic CardiomyopathyMartin Maron, MD; Tufts-New England Medical Center

In this large HCM cohort, myocardial fibrosis detected by CMR was associated with greaterlikelihood of ventricular tachyarrhythmias on ambulatory Holter ECG. Therefore, CMRidentifies HCM patients having increased susceptibility to ventricular tachyarrhythmias withimplications for sudden death risk stratification.

17:00 17:12 (234) A Novel In Vivo Marker for Ischemic Tissue Injury Early AfterCoronary OcclusionHassan Abdel-Aty, MD; University of Calgary

We aimed at identifying the earliest time point at which T2-weighted imaging visually identifiesacute ischemia in a dog model(n=7).T2 imaging detected ischemia 28±4 minutes after coronaryocclusion before the onset of irreversible damage as identified by late gadolinium enhancement

17:15 18:45 Parallel Session - CASES Los Angeles RoomModerators: Sven Plein, MD, PhD; University of LeedsSanjay Prasad, MD; Royal Brompton HospitalPanel: CT (Where Relevant to CMR) - Tracy Callister, MD; Tennessee Heart and Vascular Institute, PC

Tricky CMR Cases - Eric Larose, DVM, MD; Universite LavalCardiomyopathy - James Moon, MD; The Heart HospitalIschemic Heart Disease - Anthony Fuisz, MD; Washington Hospital Center

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17:15 18:45 Parallel Session - Interventional CMR - 1 Beverly Hills RoomModerators: Robert Lederman, MD; NIH/NHLBIAlexander Dick, MD; Sunnybrook Health Sciences Centre

17:30 17:45 Real-Time Interactive Acquisition PlatformJuan Santos, PhD; Stanford University

17:45 18:00 Visualization Platform for MR-Guided InterventionMike Guttman, PhD; NIH/NHLBI

18:00 18:15 Fusion: PlatformPerry Radau, PhD; Sunnybrook Hospital

18:15 18:30 Integrated Electrophysiology Platform for MR-Guided InterventionsAlbert Lardo, PhD; Johns Hopkins University

18:30 18:45 13 Program at BrighamEigil Samset, PhD; University of Oslo

17:15 18:45 Parallel Oral Abstract Session XV: CMR for Myocardial Ischemia Santa Monica RoomModerators: Joseph Selvanayagam, MD, PhD; Flinders Medical CentreW. Gregory Hundley, MD, Wake Forest University

17:18 17:30 (235) Simultaneous Myocardial First-Pass Perfusion and Strain Imagingwith DENSEHan Wen, PhD.; National Institutes of Health

In a pig ischemia model, myocardial strain and perfusion were imaged simultaneously with aT1- weighted displacement-encoded (DENSE) sequence during the first pass of Gd-DTPA.The dark-blood positive contrast of the sequence aids image registration and quantitativeperfusion mapping.

17:30 17:42 (236) Quantitative T2 Signal Intensity in Patients Undergoing StressPerfusion ImagingRoquell Wyche, MD; Washington Hospital Center

The purpose of this study is to correlate quantitative T2 weighted and stress perfusionimaging.

17:42 17:54 (237) MRI Myocardial Perfusion Quantification: Effects from ContrastDose, Imaging Plane and SequenceYi Wang, DSc; St. Francis Hospital

Myocardial rest perfusion quantification results are sequence dependent, and overestimateperfusion at widely used dosage of 0.05mM/kg. Long and short axis perfusion values arecomparable regardless of contrast dose or sequence.

17:54 18:06 (238) T2-weighted Magnetic Resonance Imaging as Marker for Area at Riskin Acute Myocardial InfarctionMartin Hadamitzky; Deutsches Herzzentrum München

Showing a strong correlation between T2 weighted MRI and preinterventional SPCECTimaging in acute myocardial infarction this study demonstrates the potential of T2 weightedMRI as a marker for the area at risk in acute myocardial infarction.

18:06 18:18 (239) Differentiating Moderate from Severe Coronary Artery StenosisUsing Quantitative Myocardial Perfusion ImagingAmit Patel, MD; University of Virginia

Both qualitative myocardial perfusion and quantitative measurement of perfusion reservecan be used to detect the presence of significant coronary artery stenosis. We show thatquantitative perfusion reserve analysis, additionally, can be used to differentiate moderatefrom severe coronary stenosis.

18:18 18:30 (240) Blood Oxygen-Sensitive SSFP Imaging for Probing the MyocardialPerfusion Reserves of Patients with Coronary Artery Disease: A Feasibility StudyRohan Dharmakumar, PhD; Northwestern University

Oxygen-sensitive myocardial imaging may be an alternative to first-pass perfusion methods.This work demonstrates that SSFP-based BOLD MRI can detect regional myocardial perfusiondeficits in patients with coronary artery disease.

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18:30 18:42 (241) Cardiac T2* MRI at 3.0 Tesla for the Detection of MyocardialIschemiaRobert Manka, MD; German Heart Institute Berlin

Cardiac T2* measurements can be used to detect myocardial ischemia in the presence ofsignificant coronary artery stenosis based on the paramagnetic properties ofdeoxyhemoglobin.

19:00 Award Presentations and Reception Plaza Pavilion

Sunday, February 3, 2008

7:00 8:00 Continental Breakfast Los Angeles Ballroom Foyer

7:00 8:00 Coffee with the Experts II: What we do in Cardiac Tumor, ARVD, Beverly Hills RoomCardiomyopathy, CHDModerator: Rossella Fattori, MD; Azienda Ospedaliera S. Orsola-MalpighiExperts: CMR of Patient With Recent Arrhythmic Espisode - Tal Geva, MD; Children's Hospital Boston

Imaging of Patient with Acute Chest Pain - Luigi Natale, MD; Catholic University of Sacred HeartCMR of Patient Presenting with Dyspnea of Sudden Onset - Charles B. Higgins, MD; UCSF Medical CenterSyncopal Episodical in a Young Patient With Normal ECG - Warren J. Manning, MD; Beth Israel Deaconess Medical Center

8:00 9:30 Parallel Session - CLINICAL Los Angeles RoomFirst-Pass CMR PerfusionModerators: Andrew Arai, MD; NIH/NHLBIMichael Jerosch-Herold, PhD; Brigham & Women's Hospital

8:00 8:15 Accelerated Techniques and Various Field Strengths for First-PassPerfusion-CMRNorbert Wilke, MD; University of Florida

8:15 8:30 Different Methods to Quantify Myocardial PerfusionPeter Gatehouse, PhD; Royal Brompton Hospital

8:30 8:45 Large Multi-Center First-Pass Perfusion CMR Studies: DiagnosticPerformanceJürg Schwitter, MD; University Hospital of Zurich

8:45 9:00 First-Pass Perfusion and PrognosisEike Nagel, MD; King’s College London

9:00 9:15 BOLD-Sensitive CMR: A Viable Alternative to First-Pass Techniques?Rohan Dharmakumar, PhD; Northwestern University

9:15 9:30 Discussion

8:00 9:30 Parallel Session - NON-CLINICAL Beverly Hills RoomUnmet Needs in CMRModerators: Elliott McVeigh, PhD; Johns Hopkins University School of MedicineDaniel K. Sodickson, MD, PhD; New York University Medical Center

8:00 8:15 The Top Ten: Key Clinical Needs to Which CMR Should RespondWarren J. Manning, MD; Beth Israel Deaconess Medical Center

8:15 8:30 Clinical Trials and Clinical Efficacy: Where Are We and WhereShould We Be?Christopher M. Kramer, MD; University of Virginia Health Systems

8:30 8:45 The Perfect Scan: Challenges and Opportunities for RapidComprehensive ImagingOrlando Simonetti, PhD; The Ohio State University

8:45 9:00 The Perfect Contrast (Agent): What We Have, What We Expect, andWhat We NeedTimothy Christian, MD; University of Vermont

9:00 9:15 How to Talk So Your Scanner Will Listen: User Interface, ScanWorkflow, And Imaging Display Today and TomorrowElliott McVeigh, PhD; Johns Hopkins University School of Medicine

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8:00 9:30 Parallel Session - CASES TO LEARN FROM Santa Monica RoomModerators: Philipp Beerbaum, MD; King's College LondonDaniel Messroghli, MD; Franz-Volhard-Klinik, Charite Universitätsmedizin BerlinPanel: Ashwin Prakash, MD; Columbia University

Shi-Joon Yoo, MD; Hospital for Sick ChildrenGautham Reddy, MD; UCSF School of MedicineAli Yilmaz, MD; Robert Bosch KrankenhausLorenzo Monti, MD, IRCCS Instituto Clinico Humanitas

9:30 10:00 Refreshment Break Los Angeles Ballroom Foyer

10:00 11:45 Parallel Session - CLINICAL Los Angeles RoomCutting-Edge Vascular CMRModerators: Stefan Ruehm, MD; UCLATim Leiner, MD; Maastricht University Hospital

10:00 10:15 High Spatial Resolution MRAStefan Ruehm, MD; UCLA

10:15 10:30 Off Resonance MRARobert R. Edelman, MD; Evanston Northwestern Healthcare

10:30 10:45 Advanced Post-Processing for MRATim Leiner, MD; Maastricht University Hospital

10:45 11:00 Intravascular Contrast MaterialKonstantin Nikolaou, MD; University of Munich

11:00 11:15 Time Resolved MRAJames Carr, MD; Northwestern University

11:15 11:30 Renal MRA and PerfusionKonstantin Nikolaou, MD; University of Munich

11:30 11:45 Discussion

10:00 11:45 Parallel Session - NON-CLINICAL Beverly Hills RoomMetabolic CMR StudiesModerators: Jürg Schwitter, MD; University Hospital of ZurichRobin Choudhury, MD; University of Oxford

10:00 10:15 Myocardial Energetics in Ischemia and Heart Failure: A Field to ExploreStefan Neubauer, MD; John Radcliffe Hospital

10:15 10:30 Metabolic Studies of Myocardial PreservationMonique Bernard, PhD; CNRS

10:30 10:45 High-Field Metabolic CMR in Animals Matthias Stuber, PhD; John Hopkins University

10:45 11:00 Hyperpolarized 13C Compounds and Pulse SequencesArnaud Comment, PhD; EPFL

11:00 11:15 First Experimental Results in Diabetic Hearts Using Hyperpolarized 13CDamian Tyler, PhD; University of Oxford

11:15 11:30 Discussion

10:00 11:45 Parallel Session - INTERVENTIONAL CMR – II Santa Monica RoomModerators: Graham Wright, PhD; Sunnybrook Health Sciences CentreMike Guttman, PhD; NIH/NHLBI

10:00 10:15 Preclinical OverviewAmish Raval, MD; University of Wisconsin Medicine and Public Health

10:15 10:30 Interventional CMR of Great VesselsKanishka Ratnayaka, MD; NIH NHLBI

10:30 10:45 Clinical-Grade Active MRI DevicesOzgur Kocaturk, PhD; NIH/NHLBI

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10:45 11:00 Thermal Imaging & Ablation LesionsDana Peters, PhD; Harvard Medical School

11:00 11:15 Guidewire Concepts for Interventional CMR Sascha Krueger, PhD; Philips Research Europe

11:15 11:30 Intravascular Devices at 3T Paul Bottomley, PhD; Johns Hopkins University

11:30 11:45 I Don't Need No Stinkin X-raysReza Razavi, MD; King's College London

11:45 13:00 Lunch on Your Own

13:00 14:30 Parallel Session - CLINICAL Los Angeles RoomCMR Endpoints in Clinical TrialsModerators: Christopher M. Kramer, MD; University of Virginia Health SystemsDan Berman, MD; Cedars-Sinai Medical Center

13:00 13:15 LV Volumes and FunctionSteven Dymarkowski, MD, PhD; University Hospital Gasthuisberg

13:15 13:30 LV MassNathaniel Reichek, MD; St. Francis Hospital

13:30 13:45 Infarct Size and MORaymond Kim, MD; Duke Medical Center

13:45 14:00 Myocardial PerfusionSven Plein, MD, PhD; University of Leeds

14:00 14:15 AtherosclerosisChun Yuan, PhD; University of Washington

14:15 14:30 Discussion

13:00 14:30 Parallel Session - CLINICAL Santa Monica RoomCMR @ 3T - Solved and Unsolved ProblemsModerators: Paul Finn, MD; UCLAMatthew Robson, PhD; Oxford University

13:00 13:15 MR Physics Challenges and Solutions for CMR at 3TMichael Jerosch-Herold, PhD; Brigham & Women's Hospital / Harvard Medical School

13:15 13:30 Real Time Imaging at 3TKrishna Nayak, PhD; USC

13:30 13:45 Perfusion Imaging at 3TJoseph Selvanayagam, MD, PhD; Flinders Medical Centre

13:45 14:00 MR Coronary Angiography at 3TDebiao Li, PhD; Northwestern University

14:00 14:15 Peripheral Angiography at 3T Paul Finn, MD; UCLA

14:15 14:30 MR Spectroscopy at 3TGerald M. Pohost, MD; USC

14:30 14:45 Refreshment Break Los Angeles Ballroom Foyer

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30 11TH ANNUAL SCIENTIFIC SESSIONS • JANUARY 31–FEBRUARY 3, 2008

SCMR SCIENTIFIC SESSIONS

14:45 16:00 Clinical Plenary Session 2 - CMR and Electrophysiology Los Angeles BallroomModerators: David Bluemke, MD; Johns Hopkins HospitalTimm Dickfeld, MD, PhD; University of Maryland

14:45 15:00 Image Integration of Left Atrial Anatomy in CMRMoussa Mansour, MD; Electrophysiology Lab/Arrhythmia Service

15:00 15:15 Real-Time EPHenry Halperin, MD; Johns Hopkins

15:15 15:30 CMR of LV Scar and Inducibility of ArrhythmiaAndre Schmidt, MD, Card; Medical School of Ribeirao Preto

15:30 15:45 CMR and DyssynchronyBoaz Rosen, MD; Johns Hopkins

15:45 16:00 Point/Counterpoint: Safety of PM/ICD in CMRErgin Atalar, MD; Bilkent University

16:00 16:15 Farewell AddressCharles B. Higgins, MD, UCSF Medical Center

End of Scientific SessionsAdjourn Until Orlando ~ January 29 - February 1, 2009

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www.scmr.org 31

SCMRMODERATED POSTER SESSIONS

Moderated Poster Sessions

Friday, February 1, 2008

17:30 18:30 Moderated Poster Session – CLINICALModerators: Robert Biederman, MD; Allegheny General HospitalCarlos Rochitte, MD; Univerity of Sao Paulo Medical School

17:30 17:40 (300) Diagnostic Value of Low B Value Diffusion Weighted MRI in Patientswith Acute Myocardial InfarctionKunhiko Teraoka, MD; Tokyo Med. University

17:40 17:50 (301) Accurate Quantification of Aortic Regurgitation: Comparison of MRIwith Doppler EchocardiographyMeera Sekar; Northwestern Memorial Hospital

17:50 18:00 (302) Epicardial Fat Thickness Increases with Age, Body Mass Index andMale Sex: The Framingham Heart StudyOyama Noriko, MD, PhD; Beth Israel Deaconess Medical Center

18:00 18:10 (303) Strain-encoded (SENC) Imaging of Myocardial Function After AcuteMyocardial InfarctionMirja Neizel, MD; University Hospital Heidelberg

18:10 18:20 (304) An Non Subjective Method for Myocardial T2* Curve Fitting inThalassemiaTaigang He, PhD; Royal Brompton Hospital and Imperial College London

18:20 18:30 (305) Is Real-Time CMR Really Sensitive and Specific for Pericardial Constriction?Andrew Flett, MB BS; The Heart Hospital

Saturday, February 2, 200812:45 13:45 Moderated Poster Session - EXPERIMENTAL

Moderators: Nael Osman, PhD; Johns Hopkins UniversityHildo Lamb, MD, PhD; Leiden University Medical Center

12:45 12:55 (306) Cardiac Sodium Imaging with Phased Arrays at 3 Tesla Using a 3DUltra-Short TE (UTE) ApproachMatthew Robson, PhD; Oxford University

12:55 13:05 (307) MRI-Guided Atrio-Ventricular Node Ablation in Swine Models UsingMRI-Tracking Ehud Schmidt, PhD; GE Healthcare ASL

13:05 13:15 (308) MR-Guidance and Monitoring of Intramyocardial Delivery of VEGFGene in Coronary Artery Occlusion in Canine ModelMaythem Saeed, DVM., PhD; University of California San Francisco

13:15 13:25 (309) MR Assessment of Myocardial Perfusion, Viability and Function AfterIntramyocardial Transfer of Plasmid Expressing Two Isoforms ofHepatocyte Growth Factor in Swine ModelMaythem Saeed, DVM, PhD; University of California San Francisco

13:25 13:35 (310) Cross Correlation on 2D PCMR Velocity Data to Determine AorticPulse Wave VelocitySamuel Fielden, BS; Department of Radiology, Emory University

13:35 13:45 (311) Finite Element Modeling Integration of Cardiac MRI Structure andFunctionAlistair Young; Centre for Advanced MRI

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32 11TH ANNUAL SCIENTIFIC SESSIONS • JANUARY 31–FEBRUARY 3, 2008

SCMR TECHNOLOGIST WORKSHOP

Friday, February 1, 200814:30 14:35 Opening Remarks

Mary P. Watkins, RT; Washington University School of Medicine - St. Louis

14:35 17:25 Session I: The “How To” Basics for CMRModerator: Jack Roy, RT; University of Virginia

14:35 15:05 Cardiac Anatomy Through CMR Daniele DeMarchi, RT; CNR Pisa Laboratory

15:10 15:40 Workflow Optimization of CMR Exams Petra Keilberg, RT; CNR Pisa Laboratory

15:45 16:15 Building the Basic CMR Myocardial Function ExamMercedes Pereyra, RT; St. Luke's Episcopal Hospital

16:20 16:50 How To: CMR Coronary ImagingKraig Kissinger, RT; Beth Israel Deaconess

16:55 17:25 Implants and Devices-The Current Safety GuidelinesShelton D. Caruthers, PhD; Washington University School of Medicine

Saturday, February 2, 20088:00 10:40 Session II: Essential Physics for CMR

Moderator: Mary P. Watkins, RT; Washington University School of Medicine - St. Louis

8:00 8:50 Physics of CMR (More than the Basics)David Firmin; PhD; Royal Imperial College London

8:55 9:45 “It’s a Balancing Act” - Pulse Sequences & ParametersJordin Green, PhD; Siemens Medical Solutions

9:50 10:40 CMR Quality Control “Do’s and Don’ts”Jane Francis, DCR(R), DNM; University of Oxford

10:45 11:00 Break

11:00 13:15 Session III: Understanding and Imaging Acquired Heart DiseaseModerator: Holger Thiele, MD; University of Leipzig

11:00 11:30 Diastolic Function - The Ultimate Pump Sandor Kovacs, MD; Washington University

11:35 12:05 Aortic Disease Alex Frydrychowicz, MD; University Hospital Freiburg

12:10 12:40 Cardiomyopathies and Right Ventricular Dysplasia Ian Paterson, MD; University of Alberta

12:45 13:15 Abstract Presentations12:45 13:00 (401) New Dynamic Gradient Echo Cine for

Detection of Intracardiac ShuntsPhilip Grimaldi, RT(R)(MR); Cardiovascular Associates ofRhode Island

13:00 13:15 (402) IR-SSFP (Inversion Recovery Steady-StateFree Precession)R. Walcarius, RT; Sunnybrook Health Sciences Centre

13:15 14:15 Lunch (on own)

14:15 16:00 Session IV: Elements of Myocardial ViabilityModerator: Susan Eder, RT; Crawford Long Hospital

14:15 14:45 CMR in Acute Coronary Heart DiseaseHenning Steen, MD; University of Heidelberg

14:45 15:15 Myocardial Viability and HibernationScott Flamm, MD; Cleveland Clinic Vascular Imaging

15:15 16:00 Myocardial Perfusion at Stress and RestIgor Klem, MD; Duke Medical Center

Technologist WorkshopFriday, February 1 – Sunday, February 3, 2008

Room: Constellation BallroomOrganizer: Mary Watkins, RT; Washington University School of Medicine - St. Louis

TECHNOLOGIST

WORKSHOP

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16:00 16:15 Break16:15 18:00 Session V: CE-MRA/Case Studies

Moderator: Edward Martin, MD; Oklahoma Heart Institute

16:15 16:45 MR/CT Coronary Plaque CharacterizationEric Larose, DDM, MD, FRPCP; Hospital Laval

16:45 17:15 CE MRADaniel Thomas

17:15 18:00 Case StudiesPamela Vincent, RT; NIH

Sunday, February 3, 20088:00 11:15 Session VI: How to Navigate through Congenital Heart Disease

Moderator: David Patton, MD; Alberta Children’s Hospital

8:00 8:35 Abstract Presentations8:00 8:10 (403) Do Heart Rate, Ejection Fraction, Stroke Volume

and Cardiac Output Play a Key Role in Optimal Myocardial Nulling?June Yamrozik, BS, RT(R)(MR); Allegheny General Hospital,The Gerald McGinnis Cardiovascular Institute

8:10 8:20 (404) New Developments in Adaptive Imaging by Real-Time Prospective Tracking of Cardiac Motion on a COMB tag pre-scanAndrew Dowsey, PhD; Institute of Biomedical Engineering, Imperial College London

8:20 8:30 (405) Does Diastolic Function Improve After the Left Ventricular Pressure Afterload is Removed?Ronald Williams, BA, RT(R)(MR); Allegheny General Hospital

8:35 9:25 Pediatric CMRDavid A. Annese, RT; Children's Hospital Boston

9:30 10:20 Adult Congenital Heart DiseaseMark Fogel, MD; Children's Hospital of Philadelphia

10:25 11:05 Interventional CMRAlexander Dick, MD; Sunnybrook Hospital

11:10 11:25 Best Abstract Presentation

(406) CMR Assessment of the Mitral Valve: Technical ConsiderationsRiccardo Wage, DCR (R); Royal Brompton Hospital

11:30 12:30 Lunch (on own)12:30 15:00 Session VII: Technologies on the Rise

Moderator: Leon Axel, PhD; NYU Medical Center

12:30 13:00 New Frontiers in Cardiac MRIJack Roy, RT; University of Virginia

13:05 13:35 MR/CT/PET - Imaging Modalities ComparisonNeil Filipchuk, MD; Cardiology Consultants

13:40 14:10 CMR at 3T SpeakerMatthias Gutberlet, MD; University Leipzig

14:15 14:45 Vascular Function - CMR ImagingRene Botnar, PhD, MD; King's College London

14:45 15:00 Closing RemarksMary P. Watkins, RT; Washington University School of Medicine - St. Louis

15:00 Adjourn

Technologist Workshop ContinuedFriday, February 1 – Sunday, February 3, 2008

Room: Constellation BallroomOrganizer: Mary Watkins, RT; Washington University School of Medicine - St. Louis

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34 11TH ANNUAL SCIENTIFIC SESSIONS • JANUARY 31–FEBRUARY 3, 2008

SCMR EXHIBIT FLOOR PLAN

Society for Cardiovascular Magnetic Resonance11TH ANNUAL SCIENTIFIC SESSIONS

JANUARY 31–FEBRUARY 3, 2008HYATT REGENCY CENTURY PLAZA HOTEL

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Advanced Imaging Research Booth #27PO Box 603220Cleveland, OH 44103www.advimg.com

Cardiovascular Imaging Solutions Limited Booth #28Tamarisk, Clifden CloseArrington, Cambridge SG80BAUnited Kingdomwww.cmrtools.com

CIRCLE Cardiovascular Imaging Booth #25#130, 3553 31st Street NWCalgary, Alberta T2L 2K7Canadawww.uti.ca

Diagnosoft, Inc. Booth #83461 Kenneth DrivePalo Alto, CA 94303Tel: 866-841-9139 x1972Fax: [email protected] develops state-of-the-art software for analyzing cardiacMR images. Our flagship product is Diagnosoft HARP whichenables regional function quantification based on tagged cardiacMR images. (HARP is FDA approved.)

Elsevier-Saunders-Mosby Booth #911363 Dulcet AvenueNorthridge, CA 91326Tel: 818-831-6717Fax: [email protected] is the world’s largest medical bookpublisher. The latest radiology, cardiac and cardiac MR textbookswill be available for viewing.

GE Healthcare Booth #319900 Innovation Dr.Wauwatosa, WI 53226www.gehealthcare.com

Heart Imaging Technologies Booth #30 5003 Southpark Drive, Suite 140 Durham, NC 27713 Tel: 919-323-3001, ext 102 Fax: 866-457-3694 [email protected] www.heartit.com HeartIT™ manufactures the world's only client-free PACS.WebPAX® is a scalable solution designed by cardiologists from theground up for all imaging modalities. Images can be viewedanywhere, anytime, using nothing more than a standard webbrowser. Only HeartIT's WebPAX system uses patent-protectedprocesses to ensure that images appear exactly as physicians wantto see them. HeartIT also offers consulting services and providescore laboratory image management and analysis for multi-centerclinical trials.

ICAMRL Booth #68830 Stanford Blvd, Ste 306Columbia, MD 21045www.icamrl.org

Invivo Booth #13N27 W23676 Paul RoadPewaukee, WI 53072www.invivocorp.com

Lippincott Williams & Wilkins Booth #1711636 Andasol AvenueGranada Hills, CA 91344Tel: 818-363-0477Fax: [email protected] Williams and Wilkins is a publisher of professionalhealth information for physicians, nurses, specialized cliniciansand students. The latest cardiac imaging books will be on display.

www.scmr.org 35

SCMR2008 EXHIBITOR DIRECTORY

EXHI

BITO

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36 11TH ANNUAL SCIENTIFIC SESSIONS • JANUARY 31–FEBRUARY 3, 2008

SCMR 2008 EXHIBITOR DIRECTORY

Medis Medical Imaging Systems, Inc. Booth #32751 Miller Drive, Suite E-1Leesburg, VA 20175-8993Tel: 703-737-3795Fax: [email protected] Medical Imaging Systems is a leading provider of softwarefor the quantification of cardiovascular MR images. Get the mostout of your images with QMass® MR for analyzing cardiac MRstudies, QFlow® for velocity-encoded MR studies and QPlaque®

MR for analyzing vessel wall and plaque in multi-spectral MRstudies.

MEDRAD, Inc. Booth #15One Medrad DriveIndianola, PA 15051www.medrad.com

Philips Healthcare Booth #383000 Minuteman RoadAndover, MA 01810www.philips.com/healthcare

Pie Medical Imaging Booth #14Becanusstraat 13D6216 BX MaastrichtThe NetherlandsTel: 0031-43-328-1328Fax: [email protected] Medical Imaging, world market leader in quantitative analysissoftware for cardiology and angiography, is well known for its CAAS(Cardiovascular Angiography Analysis System) software. At theSCMR we will demonstrate the latest version of CAAS MRV and awork in progress version of our newest development: CAAS MRFlow, dedicated software for analysis of quantitative MR Flow images.

RAPID MR International, LLC Booth #7Kettelerstrasse 3-11Rimpar, 97222Germanywww.rapidbiomed.de

SA Instruments, Inc. Booth #3565 Main StreetStony Brook, NY 11790Tel: 631-689-9408Fax: [email protected] Instruments makes monitoring and gating systems forMR/CT/PET/SPECT imaging applications. Parameters includeECG(>900BPM), temperature, respiration, blood pressure,peripheral pulse, oximetry and user inputs. Waveform and trenddata can be captured, stored and displayed. A heater providestemperature control. A new multi-animal system canaccommodate up to 19 animals simultaneously.

Siemens Medical Solutions Booth #2351 Valley Stream ParkwayMalvern, PA 19355www.siemens.com

EXHIBITORDIRECTORY

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Invited SpeakersHassan Abdel-Aty, MDAnthony H. Aletras, PhDHakan Arheden, MD, PhDRavi G. Assomull, MRCPLeon Axel, PhDSonya Babu-Narayan, MB, BS, BSc, MRCPPatricia Bandettini, MDJoerg Barkhausen, MDPhilipp Beerbaum, MDMonique Bernard, PhDRebecca Beroukhim, MDPratip Bhattacharya, PhDRene Botnar, PhDPeter Buser, MDRobin Choudhury, MDTimothy Christian, MDArnaud Comment, PhDRicardo Cury, MDAlbert de Roos, MDRohan Dharmakumar, PhDAlexander Dick, MD, PhDSteven Dymarkowski, MD, PhDRobert R. Edelman, MDMichael Elliott, MDRossella Fattori, MDChris Francois, MD Anthony Fuisz, MDPeter Gatehouse, PhDJacob (Koos) Geleijns, PhDBernhard Gerber, MDTal Geva, MDJames W. Goldfarb, PhD Hyun Woo Goo, MDWilliam Gottliebson, MDGerald F. Greil, MD

John Grizzard, MDMatthias Gutberlet, MDMike Guttman, PhDWillem Helbing, MDCharles B. Higgins, MDTareq Ibrahim, MDMichael Jerosch- Herold, PhDPeter Kellman, PhDWon Yong Kim, MDRobert A. Kloner, MDGert Klug, MDFrank KoberOzgur Kocaturk, PhDSebastian Kozerke, PhDDara Kraitchman, VMD, PhDRajesh Krishnamurty, MDGabriele Krombach, MDAndreas Kumar, MDRaymond Kwong, MDHildo Lamb, MD, PhDEric Larose, DVM, MDRiccardo LattanziRobert Lederman, MDPeter Libby, MDMasimo Lombardi, MDJoachim Lotz, MDNaeem Merchant, MDDaniel Messroghli, MDLorenzo Monti, MDJames Moon, MDVivek Muthurangu, MDSaul Myerson, MDKrishna Nayak, PhDThoralf Niendorf, PhDKaren Ordovas, MD

Cengizhan Ozturk, PhDDavid Patton, MDDana Peters, PhDSteffen Petersen, PhDSven Plein, MD, PhDGerald M. Pohost, MDAndrew Powell. MDAshwin Prakash, MDSanjay Prasad, MDHarald Quick, MDPerry Radau, PhDFrank Rademakers, MDKanishka Ratnayaka, MDAmish Raval, MDGautham Reddy, MDMatthew Robson, PhDCarlos Rochitte, MDBoaz Rosen, MDStefan Ruehm, MDEigil Samset, PhDAndre Schmidt, MDJeanette Schulz-Menger, MDDaniel K Sodickson, MD, PhDDavid E. Sosnovik, MDPhil Spevak, MDOliver Strohm, MDWen-Yih Tseng, MD, PhDAlexander van Straten, MDRobert Weiss, PhDJos Westenberg, MDJames White, MDBernd M. Wintersperger, MDAli Yilmaz, MDShi-Joon Yoo, MD

Oral Abstract PresentersKhaled Abd-Elmoniem, PhDPeter Alter, MD Amol Bahekar, MD MPHAaron Bell, MB.ChB, MRCPCHRené Botnar, PhDChristos Bourantas Craig BrobergMarcus Carlsson, MD, PhDKamaldeep Chawla, MD, DNB Card.Sylvia Chen, MBBSMichael Chuang, MDJelena Curcic Anna Czajka, MDErica Dall'Armellina, MDJay Detsky Rohan Dharmakumar, PhDIngo Eitel, MDAbdel-Monem El-Sharkawy Zhaoyang Fan, MScVeronica Fernandes, MD, PhDBrandon Fornwalt, BSBrent A. French, PhDBernhard Gerber, MD Tjeerd Germans William Gottliebson, MD MSLars Grosse-Wortmann, MDHeynric Grotenhuis, MDMartin Hadamitzky

Sebastiaan Hammer Allison Hays, MDSarah Hussain Neil Isaac Aditya Jain, MBBS, MPHMarkus Jochims M. Khalid, MDYoon-Chul Kim, MSSharon Kirschbaum, MD Benjamin Knowles John-Peder Kvitting, MD, PhDDaniel Lee, MDVeronica Lenge, MDScott Lipnick Xin Liu, MD Robson Macedo, MDAshkan Malayeri, MDSangeeta Mandapaka, MDRobert Manka, MDMartin Maron, MDKyle McCommis, BSRaymond Migrino, MDSaul Myerson, MD MRCP FESCMotonori Nagata Robin Nijveldt, MDRory O'Hanlon, MRCPINathan Pack Amit Patel, MD

Amol Pednekar, PhDVikas Rathi, MDKanishka Ratnayaka, MDOliver Rider Jose Rodriguez Palomares, MD Andrea Rutz Maythem Saeed, DVM, PhDJavier Sanz, MDAntti Saraste Tim Schäufele, MDJoseph Selvanayagam, MBBS, FRACPAparna Singhal Elmar Spuentrup, MDKartik Sundareswaran, MSKyunghyun Sung, MSTarinee Tangcharoen, MDAnderanik Tomasian Sergio Uribe Arancibia, MSc Rutger vd Meer, MDHan Wen, PhDRoquell Wyche, MDMayumi Yamada, MDQi Yang Anja Zagrosek, MD Lei Zhang Zhuoli Zhang Zungho Zun, MS

Disclosures of the 11th Annual Scientific Sessions of the Society for Cardiovascular Magnetic Resonance (“SCMR”)

It is the policy of the University of Minnesota Office of Continuing Medical Education (CME), in accordance with the Accreditation Council for Continuing Medical Education (ACCME), to ensure balance, independence, objectivity, and scientific rigor in all CME activities.

Anyone engaged in content development, planning or presentation completed a disclosure form.

The following people have indicated that they have no relevant personal financial relationships:

www.scmr.org 37

SCMRFACULTY DISCLOSURES

FACU

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38 11TH ANNUAL SCIENTIFIC SESSIONS • JANUARY 31–FEBRUARY 3, 2008

SCMR FACULTY DISCLOSURES

Invited SpeakersAndrew Arai, MD38

Ergin Atalar, PhD54

Michael Atalay, PhD46

Daniel K. Berman, MD12

Robert S. Biederman, MD25

David Bluemke, MD15

Paul Bottomley, PhD44

Matthew Budoff, MD, PhD13

Tracy Callister, MD13

James Carr, MD2

Milind Desai, MD30

Timm Dickfield, MD, PhD6

Fred Epstein, PhD11

Zahi Fayad, PhD19

Victor Ferrari, MD50

Paul Finn, MD39

Scott Flamm, MD33

Mark Fogel, MD38

Tom Foo, PhD14

Matthias G. Friedrich, MD52

Henry Halperin, MD48

W. Gregory Hundley, MD34

Robert Judd20

Raymond Kim, MD43

Christopher M. Kramer, MD28

Sascha Krueger, PhD30

Titus Lanz, PhD35

Albert Lardo, PhD22

Gerhard Laub, PhD38

Tim Leiner, MD5

Debiao Li, PhD41

Joao Lima, MD18

Warren J. Manning, MD30

Moussa Mansour, MD49

Edward T. Martin, MD13

Elliott McVeigh, PhD44

Eike Nagel, MD8

Luigi Natale, MD4

Stefan Neubauer, MD38

Konstantin Nikolaou, MD5

Nael Osman, PhD53

Dudley Pennell, MD42

Reza Razavi, MD30

Nathaniel Reichek, MD27

Hajime Sakuma, MD47

Juan Santos, PhD21

Michael Schär, PhD30

Jürg Schwitter, MD15

Joseph Selvanayagam, MD, PhD29

Steve Shea, PhD37

Orlando Simonetti, PhD38

Matthias Stuber, PhD32

Andrew Taylor, MD24

Jeffrey Tsao, PhD26

Damian Tyler, PhD15

Rob van der Geest, PhD23

Albert van Rossum, MD38

Jens Vogel-Claussen, MD40

Sam Wickline, MD, PhD31

Steven Wolff, MD, PhD17

Graham Wright, PhD15

Edwin Wu, MD10

Chun Wyan, PhD51

Yudong Zhu, PhD13

Oral Abstract PresentersTaigang He, PhD45

Peter Hunold, MD3

Amol Pednekar, PhD30

Guenter Pilz, MD, FESC16

Juan Santos21

Ajit Shankaranarayanan15

S David Smith, PhD36

Jeroen Sonnemans30

Yi Wang, DSc1

Jonathan Weinsaft7

1. AHA SDG#0435311N2. Astellas3. Bayer Schering Pharma, GE Healthcare,

Siemens Medical Solutions, Guerbet4. Bayer; GE5. Bayer; Schering Plough6. Biosense7. Bristol Myers Squibb Medical Imaging8. BSR; GE; Philips9. Canadian Institute of Health Research

Strategic Training fellow in TORCH(Tomorrow’s Research Cardiovascular HealthProfessionals)

10. CU Therapeutics11. EPIX Pharmaceuticals Inc.12. Flouran Pharma; BMS, Siemens, Astellas

Healthcare, Tyco Mallinckrodt; SpectrumDynamics; Cedars Sinai Medical Center

13. GE14. GE Global Research15. GE Healthcare16. GE Healthcare Buchler17. GE Healthcare; NeoSoft, LLC, NeoCoil LLC18. GE/Astellas19. GSK, Merck, Pfizer, BMS

20. Heart Imaging Technologies; Inventor onpatent owned by Northwestern University

21. Heart Vista, Inc.22. Imricor23. Medis Medical Imaging Systems24. Medtronic; Siemens Medical Solutions;

British Heart Foundation; UK Department ofHealth; Higher Education Funding Councilof England; UCL Institute of Child Health

25. MSOP/CVT; NIH/NHLBI/AHA/MSP26. Novartis27. Novartis; GSK28. Novartis; Merck; Siemens Medical Solutions;

Astellas, Reliant29. Pfizer, Merck-Modente30. Philips Medical Systems31. Philips Medical Systems; Kereos, Inc.32. Philips Medical Systems; NIH; Diagnosoft33. Philips Medical Systems; Siemens Medical

Solutions; EagleVision Pharmaceuticals; Vital Images, Inc.

34. Prova, Inc.35. Rapid Biomedical; Rapid MRI36. SA Instruments, Inc37. Siemens Corporate Research, Inc.

38. Siemens Medical Solultions, Inc.39. Siemens Medical Solutions;

Berlex Laboratories40. Siemens Medical Solutions41. Siemens, Bracco42. Siemens; Apotex; Novartis;43. Siemens; Co-founder of Heart IT44. Surgi-Vision Inc.45. This work was supported by NIH Grant: R01

DK66084-01.46. Toshiba Medical47. Toshiba, Philips, Bayer, Schering48. Zoll; Imricor49. Bard Electrophysiology50. GSK51. Pfizer; Astra Zeneca; GE; Philips Medical

Systems; VP Diagnostics; BG Medical52. Circle Medical Imaging, Inc., Calgary53. Diagnosoft, Inc.54. Surgi-vision, Troy Ka Med

The following Speakers have indicated that they have relationships with the entries listed below which, in the context

of their presentation(s), could be perceived as a potential conflict of interest (e.g., direct research funding from a

commercial organization, etc.). Please see the footnotes below for their conflict.

FACULTYDISCLOSURES

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SCMR NOTES

40 11TH ANNUAL SCIENTIFIC SESSIONS • JANUARY 31–FEBRUARY 3, 2008

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SCMRNOTES

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SCMR NOTES

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Save the DatesJanuary 29 – February 1, 2009

Orlando 12th Annual Scientific SessionsRosen Shingle Creek, Orlando, FLwww.rosenshinglecreek.com

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