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  • $1*( &HOOV $8*867 · 7kh uhvxowv iru &hoo ([fkdqjh duh vxppdul]hg lq 7deoh 0r ohfxodu w\slqj...
15
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$1*( &HOOV $8*867 · 7kh uhvxowv iru &hoo ([fkdqjh duh vxppdul]hg lq 7deoh 0r ohfxodu w\slqj uhvxowv iru lqglylgxdo oderudwrulhv duh olvwhg lq 7deohv ± iru hdfk vdpsoh dqg lqglylgxdo

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  • Table 7: Summary of the 417th Cell Exchange - DNA Typing

    12 labs High; 16 labs low- A %(n)

    12 labs High; 16 labs low- B %(n)

    12 labs High; 15 labs low- C %(n)

    A*11:01:01:01 25(3) B*13:01:01:01 8 (1) C*01:02:01:01 8 (1)A*11:01:01 8 (1) B*13:01:01 25(3) C*01:02:01 25(3)A*11:01 67(8) B*13:01 67(8) C*01:02 67(8)A*11 100(16) B*13 100(16) C*01 100(15)

    12 labs High; 16 labs low- B %(n)

    12 labs High; 15 labs low- C %(n)

    B*56:04:01 25(3) C*04:06:01 25(3)B*56:04 75(9) C*04:06 75(9)B*56 100(16) C*04 100(15)

    8 labs High; 9 labs low-DRB1 %(n)

    5 labs High; 6 labs low-DRB3/4/5 %(n)

    4 labs High; 7 labs Low-DQA1 %(n)

    8 labs High; 8 labs Low-DQB1 %(n)

    4 labs High; 5 labs Low-DPA1 %(n)

    6 labs High; 5 labs Low-DPB1 %(n)

    DRB1*11:01:01 38(3) DRB3*02:02:01 40(2) DQA1*05:05:01 50(2) DQB1*03:01:01 25(2) DPA1*02:02:02 50(2) DPB1*02:02:01 50(3)DRB1*11:01 62(5) DRB3*02:02 60(3) DQA1*05:05 50(2) DQB1*03:01 75(6) DPA1*02:02 50(2) DPB1*02:02P 17(1)DRB1*11 100(9) DRB3*02 83(5) DQA1*05 100(7) DQB1*03 100(8) DPA1*02 100(5) DPB1*02:02 33(2)

    DRB3*PRESENT 17(1) DPB1*02(DP202) 60(3)DPB1*02 40(2)

    8 labs High; 9 labs low-DRB1 %(n)

    5 labs High; 6 labs low-DRB3/4/5 %(n)

    5 labs High; 7 labs Low-DQA1 %(n)

    6 labs High; 5 labs Low-DPB1 %(n)

    DRB1*12:02:01 38(3) DRB3*03:01:03 40(2) DQA1*06:01:01 40(2) DPB1*05:01:01 50(3)DRB1*12:02 62(5) DRB3*03:01 60(3) DQA1*06:01 60(3) DPB1*05:01P 17(1)DRB1*12 100(9) DRB3*03 83(5) DQA1*06 100(7) DPB1*05:01 33(2)

    DRB3*PRESENT 17(1) DPB1*05 100(5)

    Cell 1665

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  • Table 8: Summary of the 417th Cell Exchange - DNA Typing

    12 labs High; 16 labs low- A %(n)

    12 labs High; 16 labs low- B %(n)

    11 labs High; 15 labs low- C %(n)

    A*29:02:01:01 25(3) B*35:03:01:03 17(2) C*04:01:01:14 9 (1)A*29:02:01 8 (1) B*35:03:01 17(2) C*04:01:01 27(3)A*29:02 67(8) B*35:03 66(8) C*04:01:01G 9 (1)A*29 100(16) B*35 100(16) C*04:01 55(6)

    C*04 100(15)

    12 labs High; 16 labs low- A %(n)

    12 labs High; 16 labs low- B %(n)

    11 labs High; 15 labs low- C %(n)

    A*68:01:02:01 25(3) B*51:01:01:01 17(2) C*14:02:01:01 9 (1)A*68:01:02 8 (1) B*51:01:01 17(2) C*14:02:01 27(3)A*68:01 67(8) B*51:01P 8 (1) C*14:02 64(7)A*68 100(16) B*51:01 58(7) C*14 100(15)

    B*51 100(16)

    8 labs High; 9 labs low-DRB1 %(n)

    5 labs High; 6 labs low-DRB3/4/5 %(n)

    4 labs High; 7 labs Low-DQA1 %(n)

    8 labs High; 8 labs Low-DQB1 %(n)

    4 labs High; 5 labs Low-DPA1 %(n)

    6 labs High; 5 labs Low-DPB1 %(n)

    DRB1*01:01:01 38(3) DRB5*02:02:01 40(2) DQA1*01:01:01 50(2) DQB1*05:01:01 25(2) DPA1*01:03:01:02 25(1) DPB1*04:01:01 50(3)DRB1*01:01P 12(1) DRB5*02:02 60(3) DQA1*01:01 50(2) DQB1*05:01 75(6) DPA1*01:03:01 25(1) DPB1*04:01P 17(1)DRB1*01:01 50(4) DRB5*02 17(1) DQA1*01 100(7) DQB1*05 100(8) DPA1*01:03 50(2) DPB1*04:01 33(2)DRB1*01 100(9) DRB5*PRESENT 83(5) DPA1*01 100(5) DPB1*04(DP401) 60(3)

    DPB1*04 40(2)

    8 labs High; 9 labs low-DRB1 %(n) 4 labs High-DQA1 %(n) 8 labs High-DQB1 %(n)

    4 labs High; 5 labs Low-DPA1 %(n)

    6 labs High; 5 labs Low-DPB1 %(n)

    DRB1*16:01:01 38(3) DQA1*01:02:02 50(2) DQB1*05:02:01 25(2) DPA1*02:01:01:02 25(1) DPB1*09:01:01 50(3)DRB1*16:01 62(5) DQA1*01:02 50(2) DQB1*05:02 75(6) DPA1*02:01:01 25(1) DPB1*09:01P 17(1)DRB1*16 100(9) DPA1*02:01 50(2) DPB1*09:01 33(2)

    DPA1*02 100(5) DPB1*09 100(5)

    Cell 1666

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  • Table 9: Summary of the 417th Cell Exchange - DNA Typing

    11 labs High; 14 labs low- A %(n)

    11 labs High; 14 labs low- B %(n)

    10 labs High; 13 labs low- C %(n)

    A*68:01:01:02 18(2) B*53:01:01:01 18(2) C*04:01:01 30(3)A*68:01:01 9 (1) B*53:01:01 9 (1) C*04:01:01G 10(1)A*68:01 73(8) B*53:01P 9 (1) C*04:01 60(6)A*68 100(14) B*53:01 64(7) C*04 100(13)

    B*53 100(14)

    11 labs High - A %(n)11 labs High; 14 labs low- B %(n)

    10 labs High; 13 labs low- C %(n)

    A*68:02:01:01 18(2) B*58:02:01:01 18(2) C*06:02:01:01 10(1)A*68:02:01 9 (1) B*58:02:01 9 (1) C*06:02:01 20(2)A*68:02 73(8) B*58:02 73(8) C*06:02 70(7)A*68 B*58 100(14) C*06 100(13)

    7 labs High; 7 labs low-DRB1 %(n)

    4 labs High; 4 labs low-DRB3/4/5 %(n)

    2 labs High; 6 labs Low-DQA1 %(n)

    6 labs High; 6 labs Low-DQB1 %(n)

    2 labs High; 4 labs Low-DPA1 %(n)

    5 labs High; 3 labs Low-DPB1 %(n)

    DRB1*12:01:01 29(2) DRB3*02:02:01 25(1) DQA1*01:02:01 50(1) DQB1*05:01:01 33(2) DPA1*01:03:01 50(1) DPB1*02:01:02 40(2)DRB1*12:01P 29(2) DRB3*02:02 75(3) DQA1*01:02 50(1) DQB1*05:01 67(4) DPA1*01:03 50(1) DPB1*02:01P 20(1)DRB1*12:01 42(3) DRB3*02 100(4) DQA1*01 100(6) DQB1*05 100(6) DPA1*01 100(4) DPB1*02:01 40(2)DRB1*12 100(7) DPB1*02(DP201) 100(3)

    7 labs High; 7 labs low-DRB1 %(n)

    4 labs High; 4 labs low-DRB3/4/5 %(n) 2 labs High-DQA1 %(n)

    6 labs High; 6 labs Low-DQB1 %(n)

    2 labs High; 4 labs Low-DPA1 %(n)

    5 labs High; 3 labs Low-DPB1 %(n)

    DRB1*13:02:01 29(2) DRB3*03:01:01 25(1) DQA1*01:05:01 50(1) DQB1*06:09:01 33(2) DPA1*02:01:01 50(1) DPB1*13:01:01 20(1)DRB1*13:02 71(5) DRB3*03:01 75(3) DQA1*01:05 50(1) DQB1*06:09 67(4) DPA1*02:01 50(1) DPB1*13:01P 40(2)DRB1*13 100(7) DRB3*03 100(4) DQB1*06 100(6) DPA1*02 100(4) DPB1*13:01 40(2)

    DPB1*13 100(3)

    Cell 1667

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  • Table 10: Summary of the 417th Cell Exchange - DNA Typing

    11 labs High;14 labs low- A %(n)

    11 labs High; 14 labs low- B %(n)

    11 labs High; 13 labs low- C %(n)

    A*01:02:01 9 (1) B*40:02:01 27(3) C*03:05 100(11)A*01:02 91(10) B*40:02 73(8) C*03(Cw10) 15(2)A*01 100(14) B*40(B61) 14(2) C*03 85(11)

    B*40 86(12)

    11 labs High;14 labs low- A %(n)

    11 labs High; 14 labs low- B %(n)

    11 labs High; 13 labs low- C %(n)

    A*24:02:01:06 18(2) B*49:01:01 27(3) C*07:01:01:16 9 (1)A*24:02:01 9 (1) B*49:01 73(8) C*07:01:01 18(2)A*24:02 73(8) B*49 93(13) C*07:01 73(8)A*24 100(14) B*50 7 (1) C*07 100(13)

    7 labs High; 7 labs low-DRB1 %(n)

    4 labs High; 4 labs low-DRB3/4/5 %(n)

    2 labs High; 6 labs Low-DQA1 %(n)

    6 labs High; 6 labs Low-DQB1 %(n)

    2 labs High; 4 labs Low-DPA1 %(n)

    5 labs High; 3 labs Low-DPB1 %(n)

    DRB1*04:07:01 29(2) DRB4*01:03:01 25(1) DQA1*01:05:01 50(1) DQB1*03:02:01 17(1) DPA1*01:03:01 50(1) DPB1*04:02:01 40(2)DRB1*04:07 71(5) DRB4*01:03 75(3) DQA1*01:05 50(1) DQB1*03:02P 17(1) DPA1*01:03 50(1) DPB1*04:02 60(3)DRB1*04 100(7) DRB4*01 100(4) DQA1*01 100(6) DQB1*03:02 66(4) DPA1*01 100(4) DPB1*04(DP402) 100(3)

    DQB1*03 100(6)

    7 labs High; 7 labs low-DRB1 %(n)

    2 labs High; 6 labs Low-DQA1 %(n)

    6 labs High; 6 labs Low-DQB1 %(n)

    2 labs High; 4 labs Low-DPA1 %(n)

    5 labs High; 3 labs Low-DPB1 %(n)

    DRB1*10:01:01 29(2) DQA1*03:01:01 50(1) DQB1*05:01:01 33(2) DPA1*02:01:01 50(1) DPB1*13:01:01 20(1)DRB1*10:01 71(5) DQA1*03:01 50(1) DQB1*05:01 67(4) DPA1*02:01 50(1) DPB1*13:01P 40(2)DRB1*10 100(7) DQA1*03 100(6) DQB1*05 100(6) DPA1*02 100(4) DPB1*13:01 40(2)

    DPB1*13 100(3)

    Cell 1668

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  • Table 11. Summary of the 417th Cell Exchange (Cell #1665- 1668)

    A11 83.3% A29 100.0% A68 100.0% A1 100.0%A11.1 16.7% [100.0%] [100.0%]

    [100.0%] A24 100.0%A68 100.0% B53 100.0% [100.0%]

    B13 100.0% [100.0%]B58 100.0% B61 80.0%

    B56 100.0% B35 100.0% [100.0%] [80.0%][100.0%]

    B51 100.0% Cw4 20.0% B49 100.0%Cw1 16.7% [100.0%] [20.0%] [100.0%]

    Bw4 100.0% Cw4 14.3% Cw3 20.0%[14.3%] [20.0%]

    Bw6 100.0% Bw4 100.0%Bw4 100.0%

    Bw4 100.0%Bw6 100.0%

    Bw6 100.0%

    Others Found Others Found Others Found Others FoundBw6 20.0% B60 20.0%

    (6 Samples Typed) (7 Samples Typed) (5 Samples Typed) (5 Samples Typed)

    Serological typing

    (Filipino) (Hispanic) (Black) (Hispanic)Cell 1665 Cell 1666 Cell 1667 Cell 1668

    6/15

  • Table 12. Individual laboratory results for Cell #1665 - Class I

    Center Method Other Alleles278 *11 *11 *13 *56 *01 *04 *11:01 *11:01 *13:01 *56:04 *01:02 *04:06 SSP SSO

    725 *11 *13 *56 *01 *04 SSO

    731 *11 *11 *13 *56 *01 *04 *11:01:01 *11:01:01 *13:01:01 *56:04:01 *01:02:01 *04:06:01 SSO SBT NGS

    745 *11:01:01:01 *13:01:01 *56:04:01 *01:02:01 *04:06:01 SSP SBT NGS

    747 *11 *11 *13 *56 *01 *04 *11:01:01:01 *11:01:01:01 *13:01:01:01 *56:04 *01:02:01:01 *04:06 SSP SSO NGS

    762 *11:01 *13:01 *56:04 *01:02 *04:06 NGS

    771 *11 *13 *56 *01 *04 *11:01 *13:01 *56:04 *01:02 *04:06 SSO NGS

    774 *11 *13 *56 *01 *04

    3186 *11 *13 *56 *01 *04 SSO

    3545 *11 *13 *56 *01 *04 *11:01 *13:01 *56:04 *01:02 *04:06 SSP SSO SBT

    C*01:185Q A*11:347N A*11:353 A*11:263 A*11:270 A*11:278 A*11:280 A*11:295 A*11:303 A*11:306 A*11:313Q A*11:316 A*11:320 A*11:324 A*11:328 C*04:03 C*04:286 C*01:22 C*01:85 C*01:127 C*01:142 C*01:150 C*01:151 C*01:164 C*01:172 C*01:173 C*01:174 C*01:182

    3808 *11 *11 *13 *56 *01 *04 SSO

    4079 *11:01 *13:01 *56:04 *01:02 *04:06 SSP NGS

    4251 *11:01 *11:01 *13:01 *56:04 *01:02 *04:06 NGS

    5133 *11:01:01:01 *13:01:01 *56:04:01 *01:02:01 *04:06:01 NGS

    5214 *11 *11 *13 *56 *01 *04 RT-PCR

    5462 *11 *13 *56 *01 *04 *11:01 *13:01 *56:04 *01:02 *04:06 SSO NGS

    5642 *11 *13 *56 *01 *04 SSP

    6649 *11 *13 *56 SSO

    8001 *11 *13 *56 *01 *04 SSP SSO

    8043 *11 *13 *56 *01 *04 *11:01 *13:01 *56:04 *01:02 *04:06 SSP SSO

    8103 NT 8119 *11 *13 *56 *01 *04 SSP NGS RT-PCR

    Low Resolution High ResolutionHLA-A HLA-B HLA-C HLA-A HLA-B HLA-C

    7/15

  • Table 13a: Individual laboratory results for Cell #1665 - Class II

    Center METHOD Other Alelles747 *11 *12 3*PRESENT 3*PRESENT *05 *06 *03 *03 *02 *02 *02 *05 SSP SSO NGS 771 *11 *12 *05 *06 *03 SSO NGS

    3186 *11 *12 3*02 3*03 *05 *06 *03 *02 *02(DP202) *05 SSO 3545 *11 *12 SSP SSO SBT 3808 *11 *12 NT NT *05 *06 *03 *03 *02 *02 *02(DP202) *05 SSO 5214 *11 *12 3*02 3*03 *05 *06 *03 *03 *02 *02 *02(DP202) *05 RT-PCR 5462 *11 *12 3*02 3*03 *05 *06 *03 *02 NT NT SSO NGS 8001 *11 *12 3*02 3*03 *05 *06 *03 SSP SSO

    8119 *11 *12 3*02 3*03 *03 *02 *05SSP NGSRT-PCR

    Table 13b: Individual laboratory results for Cell #1665 - Class II

    Center METHOD Other Alelles

    745 *11:01:01 *12:02:01 *03:01:01 *03:01 *02:02:01 *05:01:01 SSP SBT NGS DQB1*03:297 747 *11:01:01 *12:02:01 3*02:02:01 3*03:01:03 *05:05:01 *06:01:01 *03:01 *03:01 *02:02:02 *02:02:02 *02:02:01 *05:01:01 SSP SSO NGS DQB1*03:297 771 *11:01 *12:02 *03:01 SSO NGS

    3545 *11:01 *12:02 SSP SSO SBT

    4079 *11:01 *12:02 3*02:02 3*03:01 *05:05 *06:01 *03:01 *02:02 *02:02 *05:01 SSP NGS

    5133 *11:01:01 *12:02:01 3*02:02:01 3*03:01:03 *05:05:01 *06:01:01 *03:01:01 *02:02:02 *02:02:01 *05:01:01 NGSDPB1*547:01 DPB1*744:01

    5462 *11:01 *12:02 3*02:02 3*03:01 *05:05 *06:01 *03:01 *02:02 *02:02P *05:01P SSO NGSDPB1*547:01 DPB1*744:01

    8001 *11:01 *12:02 3*02:02 3*03:01 *06:01 *03:01 *02:02 *05:01 SSP SSO

    8119 *03:01SSP NGSRT-PCR

    High resolutionDRB1 DRB3/4/5 DQA1 DQB1 DPA1 DPB1

    Low resolutionDRB1 DRB3/4/5 DQA1 DQB1 DPA1 DPB1

    8/15

  • Table 14. Individual laboratory results for Cell #1666 - Class I

    Center Method Other Alleles278 *29 *68 *35 *51 *04 *14 *29:02 *68:01 *35:03 *51:01 *04:01 *14:02 SSP SSO 725 *29 *68 *35 *51 *04 *14 SSO731 *29 *68 *35 *51 *04 *14 *29:02:01 *68:01:02 *35:03:01 *51:01:01 *04:01:01 *14:02:01 SSO SBT NGS 745 *29:02:01:01 *68:01:02:01 *35:03:01:03 *51:01:01 *04:01:01 *14:02:01 SSP SBT NGS 747 *29 *68 *35 *51 *04 *14 *29:02:01:01 *68:01:02:01 *35:03:01 *51:01:01:01 *04:01:01 *14:02:01 SSP SSO NGS762 *29:02 *68:01 *35:03 *51:01 *04:01 *14:02 NGS 771 *29 *68 *35 *51 *04 *14 *29:02 *68:01 *35:03 *51:01 *04:01 *14:02 SSO NGS 774 *29 *68 *35 *51 *04 *14

    3186 *29 *68 *35 *51 *04 *14 SSO

    3545 *29 *68 *35 *51 *04 *14 *29:02 *68:01 *35:03 *51:01 SSP SSO SBT

    A*29:134 A*29:135 B*35:344 B*35:399 B*35:434 B*35:442 B*35:457 B*51:269 B*51:270 B*51:271 B*51:285 B*51:286 B*51:289 B*51:296 B*51:297 B*51:308 B*51:309 A*29:95 A*29:100 A*29:119 A*29:120 A*29:121 A*68:152 B*51:193 B*51:224 B*51:230 B*51:232 B*51:248 B*51:249 B*51:250 B*51:260 B*51:262

    3808 *29 *68 *35 *51 *04 *14 SSO 4079 *29:02 *68:01 *35:03 *51:01 *04:01 *14:02 SSP NGS 4251 *29:02 *68:01 *35:03 *51:01 *04:01 *14:02 NGS 5133 *29:02:01:01 *68:01:02:01 *35:03:01:03 *51:01:01:01 *04:01:01:14 *14:02:01:01 NGS5214 *29 *68 *35 *51 *04 *14 RT-PCR5462 *29 *68 *35 *51 *04 *14 *29:02 *68:01 *35:03 *51:01P *04:01 *14:02 SSO NGS B*51:289 5642 *29 *68 *35 *51 *04 *14 SSP 6649 *29 *68 *35 *51 SSO8001 *29 *68 *35 *51 *04 *14 SSP SSO8043 *29 *68 *35 *51 *04 *14 *29:02 *68:01 *35:03 *51:01 *04:01:01G *14:02 SSP SSO 8103 NT 8119 *29 *68 *35 *51 *04 *14 SSP NGS RT-PCR

    Low Resolution High ResolutionHLA-A HLA-B HLA-C HLA-A HLA-B HLA-C

    9/15

  • Table 15a: Individual laboratory results for Cell #1666 - Class II

    Center METHOD Other Alelles747 *01 *16 5*PRESENT *01 *01 *05 *05 *01 *02 *04 *09 SSP SSO NGS 771 *01 *16 *01 *05 *05 SSO NGS

    3186 *01 *16 5*02 *01 *01 *05 *05 *01 *02 *04(DP401) *09 SSO 3545 *01 *16 SSP SSO SBT3808 *01 *16 NT NT *01 *01 *05 *05 *01 *02 *04(DP401) *09 SSO 5214 *01 *16 5*02 *01 *01 *05 *05 *01 *02 *04(DP401) *09 RT-PCR 5462 *01 *16 5*02 NP *01 *01 *05 *05 *01 *02 NT NT SSO NGS 8001 *01 *16 5*02 *01 *05 *05 SSP SSO

    8119 *01 *16 5*02 *05 *05 *04 *09SSP NGSRT-PCR

    Table 15b: Individual laboratory results for Cell #1666 - Class II

    Center METHOD Other Alelles745 *01:01:01 *16:01:01 *05:01 *05:02:01 *04:01:01 *09:01:01 SSP SBT NGS

    747 *01:01:01 *16:01:01 5*02:02:01 *01:01:01 *01:02:02 *05:01:01 *05:02 *01:03:01:02 *02:01:01:02 *04:01:01 *09:01:01 SSP SSO NGS

    DQB1*05:241 DPB1*350:01 DPB1*899:01

    771 *01:01 *16:01 *05:01 *05:02 SSO NGS

    3545 *01:01 *16:01 SSP SSO SBT DRB1*01:100

    4079 *01:01 *16:01 5*02:02 *01:01 *01:02 *05:01 *05:02 *01:03 *02:01 *04:01 *09:01 SSP NGS

    5133 *01:01:01 *16:01:01 5*02:02:01 *01:01:01 *01:02:02 *05:01:01 *05:02:01 *01:03:01 *02:01:01 *04:01:01 *09:01:01 NGSDPB1*350:01 DPB1*899:01

    5462 *01:01P *16:01 5*02:02 NP *01:01 *01:02 *05:01 *05:02 *01:03 *02:01 *04:01P *09:01P SSO NGS

    DPB1*350:01 DPB1*899:01 DRB1*01:100

    8001 *01:01 *16:01 5*02:02 *05:01 *05:02 *04:01 *09:01 SSP SSO

    8119 *05:01 *05:02 SSP NGSRT-PCR

    High resolutionDRB1 DRB3/4/5 DQA1 DQB1 DPA1 DPB1

    Low resolutionDRB1 DRB3/4/5 DQA1 DQB1 DPA1 DPB1

    10/15

  • Table 16. Individual laboratory results for Cell #1667 - Class I

    Center Method Other Alleles278 *68 *68 *53 *58 *04 *06 *68:01 *68:02 *53:01 *58:02 *04:01 *06:02 SSP SSO 725 *68 *53 *58 *04 *06 SSO731 *68 *68 *53 *58 *04 *06 *68:01:01 *68:02:01 *53:01:01 *58:02:01 *04:01:01 *06:02:01 SSO SBT NGS 745 *68:01:01:02 *68:02:01:01 *53:01:01:01 *58:02:01:01 *04:01:01 *06:02:01:01 SSP SBT NGS747 NT NT SSP SSO NGS762 *68:01 *68:02 *53:01 *58:02 *04:01 *06:02 NGS A*68:27 A*68:39 771 *68 *68 *53 *58 *04 *06 *68:01 *68:02 *53:01 *58:02 *04:01 *06:02 SSO NGS 774 *68 *68 *53 *58 *04 *06

    3186 *68 *68 *53 *58 *04 *06 SSO

    3545 *68 *68 *53 *58 *04 *06 *68:01 *68:02 *53:01 *58:02 SSP SSO SBT

    A*68:188 A*68:211 B*58:104 A*68:27 A*68:39 A*68:163 A*68:198 A*68:216N B*53:51 B*53:54

    3808 *68 *68 *53 *58 *04 *06 SSO4079 NT NT NT NT NT NT NT NT NT NT NT NT SSP NGS 4251 *68:01 *68:02 *53:01 *58:02 *04:01 *06:02 NGS 5133 *68:01:01:02 *68:02:01:01 *53:01:01:01 *58:02:01:01 *04:01:01 *06:02:01 NGS 5214 *68 *68 *53 *58 *04 *06 RT-PCR 5462 *68 *68 *53 *58 *04 *06 *68:01 *68:02 *53:01P *58:02 *04:01 *06:02 SSO NGS B*53:545642 *68 *53 *58 *04 *06 SSP6649 *68 *53 *58 SSO8001 *68 *53 *58 *04 *06 SSP SSO8043 *68 *68 *53 *58 *04 *06 *68:01 *68:02 *53:01 *58:02 *04:01:01G *06:02 SSP SSO 8103 NT 8119 *68:01 *68:02 *53:01 *58:02 *04:01 *06:02 SSP NGS RT-PCR

    Low Resolution High ResolutionHLA-A HLA-B HLA-C HLA-A HLA-B HLA-C

    11/15

  • Table 17a: Individual laboratory results for Cell #1667 - Class II

    Center METHOD Other Alelles747 NT SSP SSO NGS771 *12 *13 *01 *05 *06 SSO NGS774

    3186 *12 *13 3*02 3*03 *01 *01 *05 *06 *01 *02 *02(DP201) *13 SSO 3545 *12 *13 SSP SSO SBT3808 *12 *13 NT NT *01 *01 *05 *06 *01 *02 *02(DP201) *13 SSO 5214 *12 *13 3*02 3*03 *01 *01 *05 *06 *01 *02 *02(DP201) *13 RT-PCR 5462 *12 *13 3*02 3*03 *01 *01 *05 *06 *01 *02 NT NT SSO NGS 8001 *12 *13 3*02 3*03 *01 *05 *06 SSP SSO

    Table 17b: Individual laboratory results for Cell #1667 - Class II

    Center METHOD Other Alelles745 *12:01:01 *13:02:01 *05:01:01 *06:09:01 *02:01:02 *13:01 SSP SBT NGS DPB1*107:01 747 NT SSP SSO NGS771 *12:01 *13:02 *05:01 *06:09 SSO NGS

    3545 *12:01 *13:02 SSP SSO SBT DRB1*12:10 4079 NT NT NT NT NT NT NT NT NT NT NT NT SSP NGS 5133 *12:01:01 *13:02:01 3*02:02:01 3*03:01:01 *01:02:01 *01:05:01 *05:01:01 *06:09:01 *01:03:01 *02:01:01 *02:01:02 *13:01:01 NGS

    5462 *12:01P *13:02 3*02:02 3*03:01 *01:02 *01:05 *05:01 *06:09 *01:03 *02:01 *02:01P *13:01P SSO NGS

    DPB1*352:01 DPB1*107:01 DPB1*133:01 DRB1*12:10

    8001 *12:01 *13:02 3*02:02 3*03:01 *05:01 *06:09 *02:01 *13:01 SSP SSO

    8119 *12:01P *13:02 3*02:02 3*03:01 *05:01 *06:09 *02:01 *13:01PSSP NGSRT-PCR

    High resolutionDRB1 DRB3/4/5 DQA1 DQB1 DPA1 DPB1

    Low resolutionDRB1 DRB3/4/5 DQA1 DQB1 DPA1 DPB1

    12/15

  • Table 18. Individual laboratory results for Cell #1668 - Class I

    Center Method Other Alleles278 *01 *24 *40 *49 *03 *07 *01:02 *24:02 *40:02 *49:01 *03:05 *07:01 SSP SSO 725 *01 *24 *40 *49 *03 *07 SSO 731 *01 *24 *40 *49 *03 *07 *01:02 *24:02:01 *40:02:01 *49:01:01 *03:05 *07:01:01 SSO SBT NGS 745 *01:02 *24:02:01:06 *40:02:01 *49:01:01 *03:05 *07:01:01 SSP SBT NGS747 NT SSP SSO NGS762 *01:02 *24:02 *40:02 *49:01 *03:05 *07:01 NGS 771 *01 *24 *40 *49 *03 *07 *01:02 *24:02 *40:02 *49:01 *03:05 *07:01 SSO NGS 774 *01 *24 *40 *49 *03 *07

    3186 *01 *24 *40 *50 *03 *07 SSO

    3545 *01 *24 *40 *49 *03 *07 *01:02 *24:02 *40:02 *49:01 *03:05 *07:01 SSP SSO SBT

    A*24:473Q A*24:474 A*24:479Q B*40:444 B*49:62 B*49:65 C*03:335 C*03:407 C*03:482 C*07:823 C*07:843 A*24:352 A*24:353 A*24:402 A*24:418 A*24:419 A*24:422 A*24:436 A*24:437 A*24:443 A*24:448N A*24:451 A*24:454 A*24:460 A*24:463 A*24:464 A*24:465 A*24:466 A*24:469 A*24:470 B*40:303 B*40:356 B*40:384 B*40:405 B*40:442 C*07:06 C*07:18 C*07:343 C*07:419 C*07:458 C*07:591 C*07:610 C*07:615 C*07:618 C*07:617 C*07:619 C*07:657 C*07:682 C*07:687 C*07:696 C*07:721 C*07:732 C*07:735 C*07:739 C*07:762 C*07:777 C*07:781 C*07:782 C*07:805 C*07:808N C*07:813 C*07:814

    3808 *01 *24 *40 *49 *03 *07 SSO 4079 NT NT NT NT NT NT SSP NGS 4251 *01:02 *24:02 *40:02 *49:01 *03:05 *07:01 NGS 5133 *01:02:01 *24:02:01:06 *40:02:01 *49:01:01 *03:05 *07:01:01:16 NGS 5462 *01:02 *24:02 *40:02 *49:01 *03:05 *07:01 SSO NGS

    5214 *01 *24*40

    (B61) *49*03

    (Cw10) *07 RT-PCR 5462 *01 *24 *40 *49 *03 *07 SSO NGS 5642 *01 *24 *40 *49 *03 *07 SSP 6649 *01 *24 *40 *49 SSO

    8001 *01 *24*40

    (B61) *49*03

    (Cw10) *07 SSP SSO8043 *01 *24 *40 *49 *03 *07 *01:02 *24:02 *40:02 *49:01 *03:05 *07:01 SSP SSO 8103 NT 8119 *01:02 *24:02 *40:02 *49:01 *03:05 *07:01 SSP NGS RT-PCR

    Low Resolution High ResolutionHLA-A HLA-B HLA-C HLA-A HLA-B HLA-C

    13/15

  • Table 19a: Individual laboratory results for Cell #1668 - Class II

    Center METHOD Other Alelles747 NT SSP SSO NGS771 *04 *10 *01 *03 *03 *05 SSO NGS

    3186 *04 *10 4*01 *01 *03 *03 *05 *01 *02 *04(DP402) *13 SSO 3545 *04 *10 SSP SSO SBT3808 *04 *10 NT NT *01 *03 *03 *05 *01 *02 *04(DP402) *13 SSO 5214 *04 *10 4*01 *01 *03 *03 *05 *01 *02 *04(DP402) *13 RT-PCR 5462 *04 *10 4*01 NP *01 *03 *03 *05 *01 *02 NT NT SSO NGS 8001 *04 *10 4*01 *01 *03 *03 *05 SSP SSO

    Table 19b: Individual laboratory results for Cell #1668 - Class II

    Center METHOD Other Alelles

    745 *04:07:01 *10:01:01 *03:02 *05:01:01 *04:02:01 *13:01 SSP SBT NGSDQB1*03:289 DPB1*107:01

    747 NT SSP SSO NGS771 *04:07 *10:01 *03:02 *05:01 SSO NGS

    3545 *04:07 *10:01 SSP SSO SBT DRB1*04:92 4079 NT NT NT NT NT NT NT NT NT NT NT NT SSP NGS 5133 *04:07:01 *10:01:01 4*01:03:01 *01:05:01 *03:01:01 *03:02:01 *05:01:01 *01:03:01 *02:01:01 *04:02:01 *13:01:01 NGS 5462 *04:07 *10:01 4*01:03 NP *01:05 *03:01 *03:02 *05:01 *01:03 *02:01 *04:02 *13:01P SSO NGS DPB1*107:01 8001 *04:07 *10:01 4*01:03 *03:02 *05:01:01 *04:02 *13:01 SSP SSO 8119 *04:07 *10:01 4*01:03 *03:02P *05:01 *04:02 *13:01P SSP NGS RT-PCR

    High resolutionDRB1 DRB3/4/5 DQA1 DQB1 DPA1 DPB1

    Low resolutionDRB1 DRB3/4/5 DQA1 DQB1 DPA1 DPB1

    14/15

  • Table 20. Individual laboratory results for Cell #1665-1668 by serology

    Investigator

    Days Old

    Viab % A

    11

    B13

    B56

    Cw

    1

    Bw

    4

    Bw

    6

    OT

    HE

    RS

    Viab % A29

    A68

    B35

    B51

    Cw

    4

    Bw

    4

    Bw

    6

    OT

    HE

    RS

    Viab % A

    68

    B53

    B58

    Cw

    4

    Bw

    4

    OT

    HE

    RS

    Viab % A

    1

    A24

    B61

    B49

    Cw

    3

    Bw

    4

    Bw

    6

    OT

    HE

    RS

    Cecka, J. Mic 3 >95 + + + + + >95 + + + + + + >95 + + + + >95 + + + + + +

    Fort, Marylis 95 + + + + + 97 + + + + + + NT NT

    Gillis, David 7 LC + + + + + + LC + + + + + + + 90 + + + + + 90 + + + + + + +

    Loewenthal , 6 NT NT NT NT

    Permpikul, Ve 6 90 A11.1 + + + + 90 + + + + + + 90 + + + + 90 + + + + + +

    Shai, Isaac NT NT NT NT

    Stylianou, Ca 8 >95 85 + + + + + + 95 + + + + Bw6 95 + + B60 + + +

    Villard, Jean 6 80 + + + + + 80 + + + + + + NT NT

    walsh, Lisa 3 99 + + + + + 99 + + + + + + 99 + + + + 95 + + + + + +

    Cell No 1665 (Filipino) Cell No 1666 (Hispanic) Cell No 1667 (Black) Cell No 1668 (Hispanic)

    15/15


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