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8/18/2019 1. CARDIOLOGY Decompensatio
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CARDIOLOGY dr M Arman Nasution SpPD
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Congestive Heart Failure
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Gagal jantung (Heart
ailure!
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Classification
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Generally classified as the following:Left vs right failure
Systolic vs diastolic dysfunction
Backward vs forward failure
Low output vs high output cardiac failure
The degree of functional impairment
conferred by the abnormality (as in the!"# functional classification$
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ew !ork "eart #ssociation %unctional Classification
Class I: o limitation e&perienced inany activity and no symptoms fromordinary activities'
Class II : ild limitation of activity andcomfortable at rest or mild e&ertion
Class III : arked limitation of any
activity and comfortable only at rest
Class IV : #ny physical activity bringsdiscomfort and symptoms appear atrest
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Signs and symptoms
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Left Sided %ailure) Symptoms %orward %ailure: -oor systemic
circulation
+i..inessConfusionCool e&tremities at rest/asy fatigueability
/&ercise intolerance
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*ight Sided %ailure) Symptoms
Backward %ailure: Congestion of systemic capillaries
/&cess fluid accumulation in the body
-eripheral edema0 anasarca+ependent edema (foot1 ankle1 sacral$octuria#scitesLiver congestion (hepatomegaly1 2aundice and coagulopathy$
%orward %ailure: "ypotension
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Left Sided %ailure) Signs
on specific signs of respiratory distress:Tachypnea3ncreased work of breathing+ecreased vital capacity +evelopment of pulmonary edema:*ales0Crackles 4 initially at base1 throughout the lung
when severe
/&tremely severe pulmonary edema:Cyanosis (severe hypo&emia$
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Left Sided %ailure) SignsLaterally displaced ape& beat (heart enlargement$
S5 gallop rhythm (increased blood flow0 increasedintra cardiac pressure$
"eart murmurs) indicative of valvular diseases (Causeor result of heart failure$
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*ight Sided %ailure) Signs-eripheral pitting edema"epatomegaly6ugular venous pulse accentuated
by hepato2ugular reflu& (markerof fluid status$
-ositive abdomino2ugular test-arasternal heave (increased *7
pressure$#scites (late onset$
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#scites
-itting /dema of#nkle
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Cardiomegaly
-ulmonary /dema
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Biventricular %ailure-leural effusions) more common inbiventricular failures'
8nilateral failures cause right sidedeffusions (large area of right lung$
Signs:
+ullness of lung fields*educed breath sounds at lung bases
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,ther signs
Cardiomegaly
9eight loss
Tachycardia (;
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easuring elevated 67-
Common symptoms of
CC% (overview$
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"H# H#AR"Normal
Pat$olog%Heart ailure& L' R
Heart Disease Congenital& LR s$unts' RL s$unts' Ostru)ti*e
Is)$emi)& Angina' In+ar)tion' C$roni) Is)$emia' SuddenDeat$
H%pertensi*e& Le+t sided' Rig$t sided
,al*ular& AS' M,P' R$eumati)' In+e)ti*e' Non-In+e)ti*e'
Car)inoid' Arti.)ial ,al*es Cardiom%opat$%& Dilated' H%pertrop$i)' Restri)ti*e'
M%o)arditis' Ot$er
Peri)ardium& #/usions' Peri)arditis
"umors& Primar%' #/e)ts o+ Ot$er Primaries
"ransplants
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NORMAL eatures0111 L2da%
341-511 grams
617 o+ all deat$s (38 )an)er!
9all t$i):ness ; pressure(i
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"#RMSCARDIOM#GALY
DILA"A"ION' an% )$amer' or
allHYP#R"ROPHY' and )$amer'or all
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S
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Anterio
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Anterior
Lateral
Posterior
Septal
,AL,#S
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,AL,#SA,&"RICBSPID ?5 )m
MI"RAL ?? )mS#MILBNAR&PBLMONIC )m
AOR"IC 0 )m
CARDIAC AGING
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Sigmoid-s$aped *entri)ularseptum
De)reased le+t *entri)ular )a*it%
sie
In)reased le+t atrial)a*it% sie
C$amers
u):ling o+ mitral leaEets to=ard t$e
irous t$i):ening o+ leaEets
Mitral *al*e annular )al)i.) depositsAorti) *al*e )al)i.)
deposits
,al*es
At$eros)leroti) plaFue
Cal)i.) deposits
In)reased )ross-se)tional
luminal area
"ortuosit%
#pi)ardialCoronar%Arteries
Am%loid deposits
asop$ili) degeneration
(gl%)
Lipo+us)in depositionro=n atrop$%
In)reased suepi)ardial+at
In)reased mass
M%o)ardium
CARDIAC AGING
CARDIAC AGING
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CARDIAC AGING
At$eros)leroti) plaFue
#lasti) +ragmentation and )ollagena))umulation
Sinotuular jun)tion )al)i.) deposits
#longated (tortuous! t$ora)i) aorta
Dilated as)ending aorta =it$ rig$t=ard s$i+t
Aorta
RO9N
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RO9N A"ROPHY' H#AR"
LIPOBCSIN Pat$ologi) Pump
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g pPossiilitiesPrimar% m%o)ardial +ailure (MYOPA"HY!Ostru)tion to Eo= (,AL,#!
Regurgitant Eo= (,AL,#!
Condu)tion disorders (CONDBC"IONSYS"#M!
ailure to )ontain lood (9ALLIN"#GRI"Y!
CH
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CHD#INI"ION
"RIAD?! "ACHYCARDIA3! DYSPN#A
5! #D#MAAILBR# o+ ran: Starling me)$anismHBMORAL AC"ORS
Cate)$olamines (nor-epinep$rine!
ReninAngiotensionAldosteroneAtrial Natriureti) Pol%peptide (ANP!
HYP#R"ROPHY and DILA"A"ION
HYP#R"ROPHY
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HYP#R"ROPHY PR#SSBR# O,#RLOAD (CONC#N"RIC!,OLBM# O,#RLOAD (CH!
L,H' R,H' atrial' et)<
3 normal =eig$t is)$emia
5 normal =eig$t H"N
5 normal =eig$tMYOPA"HY' aorti)regurgitation
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& u ops%i di
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p %indingsCardiomegal%C$amer Dilatation
H%pertrop$% o+ m%o)ardial .ers'OCAR nu)lei
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+ id d il
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Le+t Sided ailure
Lo= output *s< )ongestionLungs
pulmonar% )ongestion and edema
$eart +ailure )ells
idne%spre-renal aotemia
salt and Euid retention
renin-aldosterone a)ti*ation natriureti) peptides
rain& Irritailit%' de)reasedattention' stupor)oma
Le+t Heart ailureS
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S%mptomsD%spnea
on e8ertion
at rest
Ort$opnearedistriution o+ perip$eral edema Euid
graded % numer o+ pillo=s needed
Paro8%smal No)turnal D%spnea (PND!
L#" Heart Failure
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L#" Heart FailureD%spnea
Ort$opnea
PND (Paro8%smal No)turnalD%spnea!
lood tinged sputum
C%anosis
#le*ated pulmonar%J9#DG#K pressure (PC9P!(nl > 3-?4 mm Hg!
ailure
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ailure#tiolog%
le+t $eart +ailure)or pulmonale
S%mptoms and signsLi*er and spleen
passi*e )ongestion (nutmeg li*er! )ongesti*e spleenomegal%
as)ites
idne%s
Pleura2Peri)ardium pleural and peri)ardial e/usions
transudates
Perip$eral tissues
Failure
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FailureA"IGB#
JDependentK edema
,D
Hepatomegal% ()ongestion!
ASCI"#S' PL#BRAL #BSION
GI
C%anosis
In)reased perip$eral *enous
pressure (C,P! (nl > 3-0 mmHg!
H#AR" DIS#AS#
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H#AR" DIS#AS#
CONG#NI"AL
(CHD!ISCH#MIC (IHD!HYP#R"#NSI,# (HHD!
,AL,BLAR (,HD!
MYOPA"HIC (MHD!
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"ricuspid atresia
1
120 "otal anomalous pulmonary venousconnection
1
136 "runcus arteriosus
4
388
"ransposition of great arteries
4
388 Aortic stenosis
4
396 Atrioventricular septal defect
5
492 oarctation of aorta5
5!! "etralog% o+ allot
!
!81 Patent du)tus arteriosus
8
836 Pulmonar% stenosis
101043Atrial septal de+e)t
424482
,entri)ular septal de+e)t
7In)iden)e per Million
Li*e irt$sMal+ormation
G#N#"ICS
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G#N#"ICSGene anormalities in onl% ?17 o+ CHD
"risomies 3?' ?5' ?4' ?' OMutations o+ genes =$i)$ en)ode +or
trans)ription +a)tors
"4
ASD',SD N3
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A"#$%&A'()A" '*'+,- "evie. of Anatomy / ysiology Assessment History and ysical Assessment
#iagnostics lanning
",&$, %F AA+%-* A#
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",&$, %F AA+%-* A#
H*'$%)%* Heart'tructures
7lood 'upply )A "A veins
onductive 'ystem 'inoatrial node A&node 7undle of His 7undle :rancur;in
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*#
*7
)('
L#
L7
S!ST/3CC3*C8L#T3,
S!ST/3CC3*C8L#T3,
)('
S!ST/3CC3*C8L#T3,
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%#(+$% A+HA*RA LA
R, L,
'A %#,
A& %#,
7(#), %F H$'
7(#),
7"AH
(">$?,
(">$?,
",&$, %F AA+%-* A#
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",&$, %F AA+%-* A#
H*'$%)%* Heartervous 'ystem ontrol
'*-A+H,+$
A"A'*-A+H,+$
",&$, %F AA+%-* A#
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",&$, %F AA+%-* A#
H*'$%)%* Heartroperties of te Heart
All or one rinciple"ytmicity,@cita:ility"efractorinessonductivityAutomaticity,@tensi:ility
",&$, %F AA+%-* A#
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",&$, %F AA+%-* A#
H*'$%)%* Heart'+"%>, &%)(-, '&B amount of :lood pumpedout .it eac contraction
H,A"+ "A+, H"B
A"#$A %(+(+ %B volume of :lood pumpedout per minute
C'& @ H"
",)%A#
AF+,")%A#
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",&$, %F AA+%-* A#
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",&$, %F AA+%-* A#
H*'$%)%* 7lood &essels
Arteries
-icrocirculation
&eins
Flo. "egulationressure gradient
Flo. resistance"ole of 7lood vessels
)ayers of te 7lood&essels
$ntima
-edia
Adventitia
",&$, %F AA+%-* A#
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",&$, %F AA+%-* A#
H*'$%)%*$"()A+$%'*'+,-$
()-%A"*
%"+A)
()-%A"* $"()A+$%
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*#
*7
)('
L#
L7
S!ST/3CC3*C8L#T3,
S!ST/3CC3*C8L#T3,
)('
S!ST/3CC3*C8L#T3,
'*'+,-$ $"()A+$%
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*#
*7
)('
L#
L7
S!ST/3CC3*C8L#T3,
S!ST/3CC3*C8L#T3,
)('
S!ST/3CC3*C8L#T3,
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H$'+%"* A# H*'$A) ,DA-ec; fordyspnea
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H$'+%"* A# H*'$A) ,DA-Heart $ Aaortic area
pulmonic area
tricuspid
mitral
Heart 'ounds'1 A& valve
closure
'2 semilunar vEclosure
'3 ventE allop'4 atrial gallop-urmursru:s
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H$'+%"* A# H*'$A) ,DA-7lood vessels$nspection
colorpallor ru:or cyanosis
circulation of e@tremitiesalpation
edema pulsesAuscultation
:ruit
#iagnostic Assessment
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#iagnostic Assessmenton$nvasive
,
#ynamic , 'tress +est
+readmill &ector
ardiogram
onocardiogram
,cocardiogram
est Dray
"adionuclide 'tudies
&enograpy
(+ #%),"
letysmograpy
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#iagnostic Assessment$nvasive
ardiac
ateteriGation
Arteriogram
Angiocardiogram
&enogram
)ympogram
7one -arro.
Aspiration'ternumiliac crestti:ia infantsB
#iagnostic Assessment
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#iagnostic Assessment7lood and (rine
'tudies7
Hematocrit
lotting time
+
++
A++,'"
lipid pro=le
serum enGymes'%+ '+ )#H>
&-A"enin +est
'cillings +est
H,-%#*A-$' -%$+%"$
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H,-%#*A-$' -%$+%"$
& nC 6 12 cm .ater-easures cardiac eIciency :ld volume
periperal resistance rigt ventricular pressure
0pt :e at mid a@illary line 5 cm :elo. testernum
dc ventilator .it reading C Juid overload C ypovolemia
H,-%#*A-$' -%$+%"$
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ulmonary Artery and ulmonaryedge ressure'.an anG cateter Joated at te rigt eartmeasures left side of te eart
$ntraarterial 7lood ressure "adial ArteryAllens +est
+,"-$%)%$,'
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+,"-$%)%$,'
&,+$)A+$% -%&,-,+ %F A$" $ / %(+ %F +H,)('
",'$"A+$% ,DHA, %F A',' ,D+,"A) /$+,"A)
,D+,"A) 7,+E A)&,%)$ / ()-%A"* A$))A"$,'
$+,"A) 7,+E '*'+,-$ A$))A"$,'
,"F('$% A&A$)A7$)$+* / -%&,-,+ %F A$))A"*7)%%# F%" ,DHA, %F A','
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lanning for Healt romotion
-odi=cation of Hig "is; Factors
romotion of irculation
revention of $nfection sypillis stap strep
german measlesenetic counselling
"ole of nutrition
Modi.)ation o+ Hig$ Ris:a)tors
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a)tors
dyslipedemia
ypertension
smo;ing
sedentarylifestyle
o:esity
stress
glucoseintolerance
alcool a:use
caKeine pollution
lanning for Healt -aintenance /
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lanning for Healt -aintenance /"estoration
7asic )ife 'upport Advanced )ife 'upport
lient it ardiac 'urgery losed Heart surgery %pen Heart 'urgery Heart +ranspant
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losed Heart surgery valvutomy
mitral commisurotomy
%pen Heart surgery
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A7B%-)$A+$%'
#*'"H*+H-$A'
+H"%-7%'$' A#()-%A"*,-7%)$'-
A"#$%,$ 'H%>
7),,#$
%(# $F,+$%
",A) FA$)(",
,),+"%)*+,$-7A)A,
%'+% '*H%'$'
H,A"+ +"A')A+
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H,A"+ +"A')A+"$+,"$A
1E ,nd 'tage of #isease
2E Freedom from ronic #isease
3E Family 'upport
4E Age L 50 yo
5E o psycological pro:lem
$-%"+A+
1E $mmunosuppressant / 'teroids 4 rs prior2E #onor"ecipient ompati:ility siGecrossmatcing
3E #onor Heart saline solution 4 up to 4 rs
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A"#$%&A'()A" #$'+("7A,'%"%A"* M $'H,-$ H,A"+ #$',A',
Arteriosclerotic Heart #isease
Angina ectoris
oronary $nsuIciency-yocardial $nfarction
%,'+$&, H,A"+ FA$)(",
H*,"+,'$%,"$H,"A) &A'()A" #$',A',
#$'%"#,"' %F +H, 7)%%#
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A$A ,+%"$'
1E '+A7),
2E ('+A7),
3E "$-,+A) coronary artery spasm
4E %+("A)
5E #,(7$+('
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$'H,-$A &' $FA"+$%$'H,-$A $FA"+$%
A$ '(7'+,"A)",''(",MH,A&$,''
'O(,,$
'(7'+,"A)
%'+"$+$&, P 'D%F 'H%>B
#("A+$% 35 -$ Q 5 -$
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