1. CARDIOLOGY Decompensatio

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    CARDIOLOGY dr M Arman Nasution SpPD

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    Congestive Heart Failure

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    Gagal jantung (Heart

    ailure!

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    Classification

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    Generally classified as the following:Left vs right failure

    Systolic vs diastolic dysfunction

    Backward vs forward failure

    Low output vs high output cardiac failure

    The degree of functional impairment

    conferred by the abnormality (as in the!"# functional classification$

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    ew !ork "eart #ssociation %unctional Classification

    Class I:  o limitation e&perienced inany activity and no symptoms fromordinary activities'

    Class II : ild limitation of activity andcomfortable at rest or mild e&ertion

    Class III : arked limitation of any

    activity and comfortable only at rest

    Class IV : #ny physical activity bringsdiscomfort and symptoms appear atrest

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    Signs and symptoms

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    Left Sided %ailure) Symptoms  %orward %ailure: -oor systemic

    circulation

    +i..inessConfusionCool e&tremities at rest/asy fatigueability

    /&ercise intolerance

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    *ight Sided %ailure) Symptoms

    Backward %ailure: Congestion of systemic capillaries

    /&cess fluid accumulation in the body

    -eripheral edema0 anasarca+ependent edema (foot1 ankle1 sacral$octuria#scitesLiver congestion (hepatomegaly1 2aundice and coagulopathy$

    %orward %ailure: "ypotension

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    Left Sided %ailure) Signs

     on specific signs of respiratory distress:Tachypnea3ncreased work of breathing+ecreased vital capacity +evelopment of pulmonary edema:*ales0Crackles 4 initially at base1 throughout the lung

    when severe

     /&tremely severe pulmonary edema:Cyanosis (severe hypo&emia$

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    Left Sided %ailure) SignsLaterally displaced ape& beat (heart enlargement$

    S5 gallop rhythm (increased blood flow0 increasedintra cardiac pressure$

    "eart murmurs) indicative of valvular diseases (Causeor result of heart failure$

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    *ight Sided %ailure) Signs-eripheral pitting edema"epatomegaly6ugular venous pulse accentuated

    by hepato2ugular reflu& (markerof fluid status$

    -ositive abdomino2ugular test-arasternal heave (increased *7

    pressure$#scites (late onset$

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    #scites

    -itting /dema of#nkle

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    Cardiomegaly

    -ulmonary /dema

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    Biventricular %ailure-leural effusions) more common inbiventricular failures'

    8nilateral failures cause right sidedeffusions (large area of right lung$

    Signs:

    +ullness of lung fields*educed breath sounds at lung bases

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    ,ther signs

    Cardiomegaly

    9eight loss

    Tachycardia (;

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    easuring elevated 67-

    Common symptoms of

    CC% (overview$

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    "H# H#AR"Normal

    Pat$olog%Heart ailure& L' R

    Heart Disease Congenital& LR s$unts' RL s$unts' Ostru)ti*e

    Is)$emi)& Angina' In+ar)tion' C$roni) Is)$emia' SuddenDeat$

    H%pertensi*e& Le+t sided' Rig$t sided

    ,al*ular& AS' M,P' R$eumati)' In+e)ti*e' Non-In+e)ti*e'

    Car)inoid' Arti.)ial ,al*es Cardiom%opat$%& Dilated' H%pertrop$i)' Restri)ti*e'

    M%o)arditis' Ot$er

    Peri)ardium& #/usions' Peri)arditis

    "umors& Primar%' #/e)ts o+ Ot$er Primaries

    "ransplants

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    NORMAL eatures0111 L2da%

    341-511 grams

    617 o+ all deat$s (38 )an)er!

    9all t$i):ness ; pressure(i

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    "#RMSCARDIOM#GALY 

    DILA"A"ION' an% )$amer' or

    allHYP#R"ROPHY' and )$amer'or all

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    S

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    Anterio

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    Anterior

    Lateral

    Posterior

    Septal

    ,AL,#S

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    ,AL,#SA,&"RICBSPID ?5 )m

    MI"RAL ?? )mS#MILBNAR&PBLMONIC )m

    AOR"IC 0 )m

    CARDIAC AGING

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    Sigmoid-s$aped *entri)ularseptum

    De)reased le+t *entri)ular )a*it%

    sie

    In)reased le+t atrial)a*it% sie

    C$amers

    u):ling o+ mitral leaEets to=ard t$e

    irous t$i):ening o+ leaEets

    Mitral *al*e annular )al)i.) depositsAorti) *al*e )al)i.)

    deposits

    ,al*es

    At$eros)leroti) plaFue

    Cal)i.) deposits

    In)reased )ross-se)tional

    luminal area

    "ortuosit%

    #pi)ardialCoronar%Arteries

    Am%loid deposits

    asop$ili) degeneration

    (gl%)

    Lipo+us)in depositionro=n atrop$%

    In)reased suepi)ardial+at

    In)reased mass

    M%o)ardium

    CARDIAC AGING

    CARDIAC AGING

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    CARDIAC AGING

    At$eros)leroti) plaFue

    #lasti) +ragmentation and )ollagena))umulation

    Sinotuular jun)tion )al)i.) deposits

    #longated (tortuous! t$ora)i) aorta

    Dilated as)ending aorta =it$ rig$t=ard s$i+t

    Aorta

    RO9N

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    RO9N A"ROPHY' H#AR"

    LIPOBCSIN Pat$ologi) Pump

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    g pPossiilitiesPrimar% m%o)ardial +ailure (MYOPA"HY!Ostru)tion to Eo= (,AL,#!

    Regurgitant Eo= (,AL,#!

    Condu)tion disorders (CONDBC"IONSYS"#M!

    ailure to )ontain lood (9ALLIN"#GRI"Y!

    CH

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    CHD#INI"ION

    "RIAD?! "ACHYCARDIA3! DYSPN#A

    5! #D#MAAILBR# o+ ran: Starling me)$anismHBMORAL AC"ORS

    Cate)$olamines (nor-epinep$rine!

    ReninAngiotensionAldosteroneAtrial Natriureti) Pol%peptide (ANP!

    HYP#R"ROPHY  and DILA"A"ION

    HYP#R"ROPHY

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    HYP#R"ROPHY PR#SSBR# O,#RLOAD (CONC#N"RIC!,OLBM# O,#RLOAD (CH!

    L,H' R,H' atrial' et)<

    3 normal =eig$t is)$emia

    5 normal =eig$t H"N

    5 normal =eig$tMYOPA"HY' aorti)regurgitation

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    & u ops%i di

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    p %indingsCardiomegal%C$amer Dilatation

    H%pertrop$% o+ m%o)ardial .ers'OCAR nu)lei

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    + id d il

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    Le+t Sided ailure

    Lo= output *s< )ongestionLungs

    pulmonar% )ongestion and edema

    $eart +ailure )ells

    idne%spre-renal aotemia

    salt and Euid retention

    renin-aldosterone a)ti*ation natriureti) peptides

    rain& Irritailit%' de)reasedattention' stupor)oma

    Le+t Heart ailureS

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    S%mptomsD%spnea

    on e8ertion

    at rest

    Ort$opnearedistriution o+ perip$eral edema Euid

    graded % numer o+ pillo=s needed

    Paro8%smal No)turnal D%spnea (PND!

    L#" Heart Failure

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    L#" Heart FailureD%spnea

    Ort$opnea

    PND (Paro8%smal No)turnalD%spnea!

    lood tinged sputum

    C%anosis

    #le*ated pulmonar%J9#DG#K pressure (PC9P!(nl > 3-?4 mm Hg!

     ailure

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    ailure#tiolog%

    le+t $eart +ailure)or pulmonale

    S%mptoms and signsLi*er and spleen

    passi*e )ongestion (nutmeg li*er! )ongesti*e spleenomegal%

    as)ites

    idne%s

    Pleura2Peri)ardium pleural and peri)ardial e/usions

    transudates

    Perip$eral tissues

     Failure

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    FailureA"IGB#

    JDependentK edema

     ,D

    Hepatomegal% ()ongestion!

    ASCI"#S' PL#BRAL #BSION

    GI

    C%anosis

    In)reased perip$eral *enous

    pressure (C,P! (nl > 3-0 mmHg!

    H#AR" DIS#AS#

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    H#AR" DIS#AS#

    CONG#NI"AL

    (CHD!ISCH#MIC (IHD!HYP#R"#NSI,# (HHD!

    ,AL,BLAR (,HD!

    MYOPA"HIC (MHD!

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    "ricuspid atresia

    120 "otal anomalous pulmonary venousconnection

    136 "runcus arteriosus

    4

     

    388 

    "ransposition of great arteries

    388 Aortic stenosis

    396 Atrioventricular septal defect

    492 oarctation of aorta5 

    5!! "etralog% o+ allot

    !81 Patent du)tus arteriosus

    836 Pulmonar% stenosis

    101043Atrial septal de+e)t

    424482

    ,entri)ular septal de+e)t

    7In)iden)e per Million

    Li*e irt$sMal+ormation

    G#N#"ICS

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    G#N#"ICSGene anormalities in onl% ?17 o+ CHD

    "risomies 3?' ?5' ?4' ?' OMutations o+ genes =$i)$ en)ode +or

    trans)ription +a)tors

    "4

    ASD',SD   N3

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    A"#$%&A'()A" '*'+,- "evie. of Anatomy / ysiology Assessment  History and ysical Assessment

    #iagnostics lanning

    ",&$, %F AA+%-* A#

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    ",&$, %F AA+%-* A#

    H*'$%)%* Heart'tructures

    7lood 'upply )A "A veins

    onductive 'ystem 'inoatrial node A&node 7undle of His 7undle :rancur;in

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    *#

    *7

    )('

    L#

    L7

    S!ST/3CC3*C8L#T3,

    S!ST/3CC3*C8L#T3,

    )('

    S!ST/3CC3*C8L#T3,

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    %#(+$% A+HA*RA LA

    R, L,

    'A %#,

    A& %#,

     7(#), %F H$'

    7(#),

    7"AH

    (">$?,

    (">$?,

    ",&$, %F AA+%-* A#

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    ",&$, %F AA+%-* A#

    H*'$%)%* Heartervous 'ystem ontrol

    '*-A+H,+$

    A"A'*-A+H,+$

     

    ",&$, %F AA+%-* A#

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    ",&$, %F AA+%-* A#

    H*'$%)%* Heartroperties of te Heart

    All or one rinciple"ytmicity,@cita:ility"efractorinessonductivityAutomaticity,@tensi:ility

    ",&$, %F AA+%-* A#

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    ",&$, %F AA+%-* A#

    H*'$%)%* Heart'+"%>, &%)(-, '&B amount of :lood pumpedout .it eac contraction

    H,A"+ "A+, H"B

    A"#$A %(+(+ %B volume of :lood pumpedout per minute

    C'& @ H"

    ",)%A#

    AF+,")%A#

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    ",&$, %F AA+%-* A#

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    ",&$, %F AA+%-* A#

    H*'$%)%* 7lood &essels

    Arteries

    -icrocirculation

    &eins

    Flo. "egulationressure gradient

    Flo. resistance"ole of 7lood vessels

    )ayers of te 7lood&essels

    $ntima

    -edia

    Adventitia

    ",&$, %F AA+%-* A#

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    ",&$, %F AA+%-* A#

    H*'$%)%*$"()A+$%'*'+,-$

    ()-%A"*

    %"+A)

    ()-%A"* $"()A+$%

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    *#

    *7

    )('

    L#

    L7

    S!ST/3CC3*C8L#T3,

    S!ST/3CC3*C8L#T3,

    )('

    S!ST/3CC3*C8L#T3,

    '*'+,-$ $"()A+$%

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    *#

    *7

    )('

    L#

    L7

    S!ST/3CC3*C8L#T3,

    S!ST/3CC3*C8L#T3,

    )('

    S!ST/3CC3*C8L#T3,

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    H$'+%"* A# H*'$A) ,DA-ec; fordyspnea 

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    H$'+%"* A# H*'$A) ,DA-Heart $ Aaortic area

     pulmonic area

     tricuspid

    mitral

    Heart 'ounds'1 A& valve

    closure

    '2 semilunar vEclosure

    '3 ventE allop'4 atrial gallop-urmursru:s

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    H$'+%"* A# H*'$A) ,DA-7lood vessels$nspection

    colorpallor ru:or cyanosis

    circulation of e@tremitiesalpation

    edema pulsesAuscultation

    :ruit

    #iagnostic Assessment

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    #iagnostic Assessmenton$nvasive

    ,

     #ynamic , 'tress +est

     +readmill &ector

     ardiogram

    onocardiogram

    ,cocardiogram

    est Dray

    "adionuclide 'tudies

    &enograpy

    (+ #%),"

    letysmograpy

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    #iagnostic Assessment$nvasive

    ardiac

    ateteriGation

    Arteriogram

    Angiocardiogram

    &enogram

    )ympogram

    7one -arro.

    Aspiration'ternumiliac crestti:ia infantsB

    #iagnostic Assessment

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    #iagnostic Assessment7lood and (rine

    'tudies7

    Hematocrit

    lotting time

    +

    ++

    A++,'"

    lipid pro=le

    serum enGymes'%+ '+ )#H>

    &-A"enin +est

    'cillings +est

    H,-%#*A-$' -%$+%"$

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    H,-%#*A-$' -%$+%"$

    & nC 6 12 cm .ater-easures cardiac eIciency  :ld volume

     periperal resistance  rigt ventricular pressure

    0pt :e at mid a@illary line 5 cm :elo. testernum

    dc ventilator .it reading  C Juid overload C ypovolemia

    H,-%#*A-$' -%$+%"$

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    ulmonary Artery and ulmonaryedge ressure'.an anG cateter Joated at te rigt eartmeasures left side of te eart

    $ntraarterial 7lood ressure "adial ArteryAllens +est

    +,"-$%)%$,'

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     +,"-$%)%$,'

    &,+$)A+$%  -%&,-,+ %F A$" $ / %(+ %F +H,)('

    ",'$"A+$%  ,DHA, %F A',' ,D+,"A) /$+,"A)

    ,D+,"A)  7,+E A)&,%)$ / ()-%A"* A$))A"$,'

    $+,"A) 7,+E '*'+,-$ A$))A"$,'

    ,"F('$% A&A$)A7$)$+* / -%&,-,+ %F A$))A"*7)%%# F%" ,DHA, %F A','

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    lanning for Healt romotion

    -odi=cation of Hig "is; Factors

    romotion of irculation

    revention of $nfection sypillis stap strep

    german measlesenetic counselling

    "ole of nutrition

    Modi.)ation o+ Hig$ Ris:a)tors

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    a)tors

    dyslipedemia

    ypertension

    smo;ing

    sedentarylifestyle

     

    o:esity

    stress

    glucoseintolerance

     alcool a:use

    caKeine pollution

    lanning for Healt -aintenance /

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    revent Future ,pisodes#$,+ lo. calorie lo. saturated fat

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    A+,%"* '7 mmHg #7 mmHg

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