(BDT209) Intel’s Healthcare Cloud Solution Using Wearables for Parkinson’s Disease Research |...

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In this session, learn how the Intel team of software engineers and data scientists, in collaboration with the Michael J Fox Foundation, built a big data analytics platform using Hadoop and other IoT technologies. The solution leverages wearable sensors and smartphone application to monitor PD patient's motor activities, 24/7. The platform collects and processes large stream of data, and enables different analytics services such as activity recognition and different PD related measurements to researchers. These machine learning algorithms are used to detect patterns in the data that can help researchers understand the progression of the disease and develop effective treatments. You leave with a comprehensive view of the tools and platforms from Intel that you can use in building your own applications on AWS. In addition there will be a deeper dive to explain the way this platforms enables near real- time analytics as part of the ingestion process. Parkinson's Disease-a neuromuscular disease that causes gradually worsening symptoms such as tremors, difficulty in movement, and sleep loss -affects over 5 million people worldwide. Because the symptoms vary from individual to individual, research into the disease is hampered by the lack of objective data. As is typical of many healthcare applications, the collection, storage, and analysis of data is complex, expensive, and time-consuming. Intel is tackling this challenge by building a solution that uses wearable devices to collect data from patients anonymously and store it securely. Sponsored by Intel.

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Moty Fania - Principal Architect, Intel

Parkinson Disease (PD)

The Hypothesis / Opportunity

The problem –

PD Big-Data is not really available

Solution

• Enable breakthroughs in Parkinson disease research through Big Data analytics

• Small disparate sources of data

• Most data is limited and unavailable

• Instrument PD patients with wearable devices for large scale, continuous 24 X 7 data collection

Patients are not able to objectively evaluate their condition

No Objective measure of Parkinson disease symptoms

Cost of trials are in the scales of $M and they take several years to complete

Very small number of patients contribute to research

Researchers can not scale to large N due to technology limitations

30subjects

5Days per Subject

0.15TBPer Subject per Day

500subjects

30Days per Subject

1GBPer Subject per Day

15TBEvery month

1000subjects

365Days per Subject

365TBPer Subject per Day

365TBEvery year

Smartphone App

Big Data Analytics

Wearable Monitor

24 x 7 monitoring

Objective measurements

Activity Identification

Anomaly Detection

Location

Movement

Medications

Sleep Patterns

Gait

Balance

Tremors

Researcher physicianPatient

7

Cloud Infrastructure

UI

Data Platform

Analytics Platform

DatacenterNetworkThing

Services

Gateway

2 Start an application1 Wear a watch

Activity recognition

Activity characteristics

symptoms identification

Activity

monitoring

8:00 9:00 10:00 11:00 12:00 13:00

8:00 9:00 10:00 11:00 12:00 13:00

8:00 9:00 10:00 11:00 12:00 13:00

8:00 9:00 10:00 11:00 12:00 13:00

Ac

tive

8:00 9:00 10:00 11:00 12:00 13:00

8:00 9:00 10:00 11:00 12:00 13:00

Ac

tive

Low Movement

8:00 9:00 10:00 11:00 12:00 13:00

8:00 9:00 10:00 11:00 12:00 13:00

Ac

tive

Low Movement

Hand

Movement

8:00 9:00 10:00 11:00 12:00 13:00

8:00 9:00 10:00 11:00 12:00 13:00

Ac

tive

Low Movement

Ac

tive

8:00 9:00 10:00 11:00 12:00 13:00

8:00 9:00 10:00 11:00 12:00 13:00

Ac

tive

Low Movement

Ac

tive

Low Movement

8:00 9:00 10:00 11:00 12:00 13:00

8:00 9:00 10:00 11:00 12:00 13:00

Ac

tive

Low Movement

Ac

tive

Low Movement

Ac

tive

8:00 9:0010:0

011:00 12:00

13:0

0

8:00 9:0010:0

011:00 12:00

13:0

0

10:00 10:12 10:24 10:36 10:48 11:00

10:00 10:12 10:24 10:36 10:48 11:00

10:00 10:12 10:24 10:36 10:48 11:00

10:00 10:12 10:24 10:36 10:48 11:00

Frequency ~5Hz – Typical to tremor

3.5 10.5 17.5 24.5 31.5

Time [sec]

Rest

Leg Tremor Indication

Rest

Leg

Tremor

Ind.

Rest

3.5 10.5 17.5 24.5 31.5

Time [sec]

8:00 9:0010:0

011:00 12:00

13:0

0

8:00 9:0010:0

011:00 12:00

13:0

0

Sitting Down

Sitting Down

Changing hand

posture while sitting

Sitting Down

Gettin

g U

p

Sitting DownHand changes position

to assist the movement

Gettin

g U

p

Sitting Down

Gettin

g U

p

Measuring movements duration can

indicate on slowness of movement

Sitting Down

Gettin

g U

p

Walking

Sitting Down

Gettin

g U

p

Walking Interrupts (e.g., turning

around, handshake)

Sitting Down

Gettin

g U

p

WalkingChanging hand posture

while walking

Sitting Down

Gettin

g U

p

Walking

70 Steps in average pace of 103

Steps per minute (in general, pace

can indicate on slowness of

movement)

Sitting Down

Gettin

g U

p

Walking Sitting Down

37

~45 Servers

Let’s look Inside

(Big) Data Ingestion

Platform-as-a-Service (PaaS) for real-time data & event processing

Analytics Services

Monitoring

& Alerting

Data

Visualization

Reporting &

Querying

Advanced Analytics Services

Time Series

Analysis

Anomaly / Change

Detection

Activity Recognition

/ Context Extraction

Smart Cities RetailIndustrial TransportationHealth

Predictive

Maintenance

Inventory &

Asset Mgmt.Cyber /

Malicious

Activity

Mobile Health

Load

Balancing

Speed Layer

Batch LayerData

Sources

Ingestion

LayerServicing

Layer

Configuration &

MetaDataWe

b

Se

rvic

es

Data Storage

Analytics

Rule Engine

Web

Site

MQT

T

Node.js

Express

Angular.js

Bootstrap

Node.js

Express

MongoDB

Message Broker

Scala

Java

Akka

Spray

Apache Kafka

Apache Phoenix

Spark

RElastic Load

Balancing

CDH 5.2

YARN

MapReduce 2

HBase (time series)

InfiniDB for AWS (aggregates)

Cache

Redis

Deployment:

AWS Cloud Formation

OpsCode Chef

Amazon VPC

Monitoring:

Nagios / Zabbix

Logging:

Logstash

Auto Scaling

Intel announced a comprehensive developer program

for hobbyists, students and entrepreneurial

developers with outreach, training and tools required

to rapidly develop, test and deploy applications for

the Internet of Things.

• Package of easy to use hardware, software &

tools, services

• Global Hackathon Challenge with prizes

• 20 City IoT Roadshow distributing 5,000 kits

• University Program with courseware and labs

starting with Carnegie Mellon

• On-line community for learning, building sharing

See Edison Live at the Intel Booth

You can use this platform to collect data and

build your own solution with Edison!

http://bit.ly/awsevals