Welcome to Molecular Biology Through Discovery Thursday, 20 September 2012 DNA Structure / Benzer...

Welcome toMolecular Biology Through Discovery

Thursday, 20 September 2012DNA Structure / Benzer (1959)

What would you like discussed in class, on any subject that has already come up?

General Questions

Can you clarify what we are using the mentors for again? I want to make sure that when I send them an email I can tell them why I need a mentor.

DNA Structure

DNA Structure

DNA Structure

DNA StructureC. What are the Chargaff rules and how they were found?

Why is C uniformly low?Genetic Imprinting

Sapienza C (1990) Sci Am Oct 52- 60

DNA methylation

Reik W, Walter J (2001) Nature Rev 2:21-32

Dana Krempels, University of Miami

Cytosine

DNA Structure

DNA Structure

0.140.370.360.13

DNA StructureSQ7. What would you expect to happen to the diffraction pattern if the helix shown in Fig. 8B-D were squashed, i.e. the helix were more tightly wound, more like a solenoid?

DNA StructureSQ7. What would you expect to happen to the diffraction pattern if the helix shown in Fig. 8B-D were squashed, i.e. the helix were more tightly wound, more like a solenoid?

?? ?

?

DNA StructureSQ7. What would you expect to happen to the diffraction pattern if the helix shown in Fig. 8B-D were squashed, i.e. the helix were more tightly wound, more like a solenoid?

??

angle?

DNA StructureSQ7. What would you expect to happen to the diffraction pattern if the helix shown in Fig. 8B-D were squashed, i.e. the helix were more tightly wound, more like a solenoid?

DNA StructureSQ7. What would you expect to happen to the diffraction pattern if the helix shown in Fig. 8B-D were squashed, i.e. the helix were more tightly wound, more like a solenoid?

?

angle?

Benzer (1959)

rII region of bacteriophage T4

Benzer (1959)

rII region of bacteriophage T4

mutation

Benzer (1959)

rII region of bacteriophage T4

Benzer (1959)Determine distances between markers by

Recombination

Benzer (1959)I still have trouble connecting recombination with the distance b/w genetic markers.

Benzer (1959)I still have trouble connecting recombination with the distance b/w genetic markers.

Richard Twyman, University of Warwick

Benzer (1959)I still have trouble connecting recombination with the distance b/w genetic markers.

Elizabeth Ellis University of Strathclyde

Results vs Conclusions

Shahroze Mandi Shaun

Bobby Supriya Tayab

Kaleigh Jonathan Michael Colleen

AbdulCailin Sue Kristen

Abdallah Celeste Neda Yordanos

Me

Coming Attractions

Goodbye fromMolecular Biology Through Discovery

Thursday, 20 September 2012