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Transcription in EukaryotesClass II promoters:
*Core Promoter
TATA box
TFIIB Recognition Element (BRE)
Initiator (Inr)
Downstream Promoter Element (DPE)
*Upstream Promoter Element
Transcription Initiation in Eukaryotes
General Transcription Factors and the Pre-initiation complex:
Transcription Initiation in EukaryotesTBP binding:
Transcription Initiation in Eukaryotes
Transcription Initiation in Eukaryotes
Schematic ModelElongation of Transcription in Eukaryotes
Polyadenylation
*CstF
*CPSF
*PAP
*PABP
RNA processing in eukaryotesAddition of poly A tail
Addition of 5’cap
Splicing
Torpedo model for transcription termination
Formation of the 5’ cap
*RNA triphosphatase
*guanylyl transferase
*methyl transferase
Transcript Processing
Functions of the Cap and Tail
ProtectionTranslatability TransportSplicing
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