PERSEN VIABILITAS

PERSEN VIABILITAS EKSTRA DAUN MINDIParameter Estimates

ParameterEstimateStd. ErrorZSig.95% Confidence Interval

Lower BoundUpper Bound

PROBITaDosis-1,727,113-15,271,000-1,949-1,505

Intercept3,604,22915,750,0003,3753,833

a. PROBIT model: PROBIT(p) = Intercept + BX (Covariates X are transformed using the base 10,000 logarithm.)

Chi-Square Tests

Chi-SquaredfbSig.

PROBITPearson Goodness-of-Fit Test242,9485,000a

a. Since the significance level is less than ,150, a heterogeneity factor is used in the calculation of confidence limits.

b. Statistics based on individual cases differ from statistics based on aggregated cases.

Cell Counts and Residuals

NumberDosisNumber of SubjectsObserved ResponsesExpected ResponsesResidualProbability

PROBIT12,699100114,528-13,444,145

22,3981002529,562-5,051,296

32,0971006349,31513,467,493

41,7961007369,2413,297,692

51,4951009884,67513,157,847

61,1931009993,8665,230,939

7,5911009099,511-9,899,995

Confidence Limits

Probability95% Confidence Limits for Dosis95% Confidence Limits for log(Dosis)b

EstimateLower BoundUpper BoundEstimateLower BoundUpper Bound

PROBITa,0102716,684..3,434..

,0201888,822..3,276..

,0301499,828..3,176..

,0401260,965..3,101..

,0501095,017..3,039..

,060971,091..2,987..

,070874,028..2,942..

,080795,381..2,901..

,090730,017..2,863..

,100674,608..2,829..

,150486,537..2,687..

,200375,241..2,574..

,250300,285..2,478..

,300245,824..2,391..

,350204,216..2,310..

,400171,266..2,234..

,450144,456..2,160..

,500122,172..2,087..

,550103,325..2,014..

,60087,151..1,940..

,65073,089..1,864..

,70060,718..1,783..

,75049,706..1,696..

,80039,777..1,600..

,85030,678..1,487..

,90022,125..1,345..

,91020,446..1,311..

,92018,766..1,273..

,93017,077..1,232..

,94015,370..1,187..

,95013,631..1,135..

,96011,837..1,073..

,9709,952..,998..

,9807,902..,898..

,9905,494..,740..

a. A heterogeneity factor is used.

b. Logarithm base = 10.

KESIMPULAN : % VIABILITAS DAUN MINDI DENGAN IC50 ADALAH 122,172 ARTINYA DOSIS YANG DAPAT DITIMBULKAN OLEH DAUN MINDI UNTUK INHIBITOR CONSENTRATION ADALAH SEBANYAK 122,172

PERSEN VIABILITAS DOKSORUBISIN

Parameter Estimates

ParameterEstimateStd. ErrorZSig.95% Confidence Interval

Lower BoundUpper Bound

PROBITaDosis-,642,103-6,208,000-,844-,439

Intercept,635,1374,627,000,498,772

a. PROBIT model: PROBIT(p) = Intercept + BX (Covariates X are transformed using the base 10,000 logarithm.)

Chi-Square Tests

Chi-SquaredfbSig.

PROBITPearson Goodness-of-Fit Test4,4054,354a

a. Since the significance level is greater than ,150, no heterogeneity factor is used in the calculation of confidence limits.

b. Statistics based on individual cases differ from statistics based on aggregated cases.

Cell Counts and Residuals

NumberDosisNumber of SubjectsObserved ResponsesExpected ResponsesResidualProbability

PROBIT12,0001002625,830,276,258

21,6991003432,4421,193,324

31,3981003339,660-6,898,397

41,0971005547,2517,461,473

5,7961005554,944-,412,549

6,4941006162,472-1,587,625

Confidence Limits

Probability95% Confidence Limits for Dosis95% Confidence Limits for log(Dosis)a

EstimateLower BoundUpper BoundEstimateLower BoundUpper Bound

PROBIT,01041120,0596156,3171544747,0264,6143,7896,189

,02015464,2232916,256371406,3484,1893,4655,570

,0308314,8291814,151150445,4063,9203,2595,177

,0405213,6021268,83976265,0113,7173,1034,882

,0503566,519948,33043900,6903,5522,9774,642

,0602581,633739,95327443,9723,4122,8694,438

,0701944,620595,12318183,3743,2892,7754,260

,0801508,862489,55012580,9833,1792,6904,100

,0901197,955409,7899002,0733,0782,6133,954

,100968,719347,8256616,5272,9862,5413,821

,150402,058175,8461855,5412,6042,2453,268

,200199,876101,623679,7362,3012,0072,832

,250109,73962,949289,6542,0401,7992,462

,30064,04940,412136,4181,8071,6072,135

,35038,88826,22169,4001,5901,4191,841

,40024,22116,75337,9431,3841,2241,579

,45015,32010,26322,3871,1851,0111,350

,5009,7605,95714,168,989,7751,151

,5506,2183,3019,392,794,519,973

,6003,9331,7636,358,595,246,803

,6502,450,9074,317,389-,042,635

,7001,487,4462,898,172-,351,462

,750,868,2061,898-,061-,686,278

,800,477,0871,190-,322-1,062,075

,850,237,032,693-,625-1,502-,159

,900,098,009,352-1,007-2,056-,453

,910,080,006,299-1,100-2,190-,524

,920,063,005,251-1,200-2,336-,601

,930,049,003,206-1,310-2,496-,685

,940,037,002,166-1,433-2,675-,780

,950,027,001,130-1,573-2,880-,887

,960,018,001,097-1,738-3,120-1,013

,970,011,000,068-1,941-3,415-1,168

,980,006,000,042-2,210-3,808-1,374

,990,002,000,020-2,635-4,428-1,698

a. Logarithm base = 10.

KESIMPULAN : % VIABILITAS DOKSORUBISIN DENGAN IC50 ADALAH 9,760 ARTINYA DOSIS YANG DAPAT DITIMBULKAN OLEH DOKURUBIN UNTUK INHIBITOR CONSENTRATION ADALAH SEBANYAK 9,760