Nature Genetics, Supplement, November 2004

Nature Genetics, Supplement, November 2004

http://anthro.palomar.edu/vary/vary_3.htm

Skin Color:Adaptation to equitorial environment

Cavalli-Sforza et al. (1994) The hisgtory and geography of human genes.

Human populations blend:Genetically, you look like your neighbors

Principal components analysis of population structure in 554 individuals.

Xing J et al. Genome Res. 2009;19:815-825

Copyright © 2009 by Cold Spring Harbor Laboratory Press

Tishkoff & Kidd (2004). Nature Genetics Supplement, 36, S21-S27

Tishkoff & Kidd (2004). Nature Genetics Supplement, 36, S21-S27

Out of Africa Theory:Greater Genetic Diversity in Africa:

Greater Heterozygosity

Tishkoff & Kidd (2004). Nature Genetics Supplement, 36, S21-S27

Out of Africa Theory:Greater Genetic Diversity in Africa:

Less Linkage Disequilibrium

http://anthro.palomar.edu/vary/vary_3.htm

http://anthro.palomar.edu/vary/vary_1.htm

Clinal Distribution Discontinuous Distribution

Hair Color

Between 85% and 95% of allgenetic variation exists within a

continental population.

Implications: asteroid

HGSS: Carey: Figure 14.1