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Introduction to BioengineeringBIOE/ENGR.80Stanford University
Spring 2020 Class Slides
Day 1611 May 2020
These slides are made freely available to the fullest extent possible. Any copyrighted images used herein are used in good faith subject to the fair use exception for education. Please contact endy@stanford.edu directly re: any copyright concerns.
Week 5 reprise
DNA sequencing (reading)
DNA synthesis (writing)
Team rules & priority-setting tools
CONCEPTSKILL
Surfing exponentials
Interconvertibility of matter and information
- Sequencing-by-synthesis; pore-based
- Phosphoramidite chemistry for low-error rates
- Quantitative change poses, “when’s the right time?”
- DNA R/W together enabling networked bio/technology
- Impact versus effort; get projects on leading-edge curve
Week 6 look ahead
Diffusion of molecules (space, time, abundances)
Programming patterns in autonomous systems
[Team Project] - Brainstorms (three themes)- Team Rules
CONCEPTSKILL
Programming patterns in living systems
https://en.wikipedia.org/wiki/Brownian_motionhttp://sciweb.nybg.org/science2/pdfs/dws/Brownian.pdf
https://www.jstor.org/stable/j.ctv7r40w6
To go twice as far takes four times as long.
1D2D3D
A particle that is twice as big, R, goes ~0.7 as far.
Diffusing particles spread out over time…
https://www.jstor.org/stable/j.ctv7r40w6
http://rpdata.caltech.edu/courses/aph162/2006/Protocols/diffusion.pdf
http://biodynamics.ucsd.edu/
What can we infer about the diffusion of biomolecules in this system?
https://www.ncbi.nlm.nih.gov/pubmed/22178928
What can we infer about the diffusion of biomolecules in this system?
https://www.ncbi.nlm.nih.gov/pubmed/22178928
What can we infer about the diffusion of biomolecules in this system?
http://biodynamics.ucsd.edu/
What can we infer about the diffusion of biomolecules in this system?
http://biodynamics.ucsd.edu/
What can we infer about the diffusion of biomolecules in this system?
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http://www.rowland.harvard.edu/labs/bacteria/movies/ecoli.php
http://www.rowland.harvard.edu/labs/bacteria/movies/ecoli.php
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