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8/8/2019 Infection of Virus
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General Characteristics of Viruses
I nfectious agents that are too small to be seen with a light microscopeParasites of animals, plants and some bacteria
That are not cellsCan replicateI nfect all cellular lifeMultiply
Only inside a living host cell (obligateintracellular parasites)Contain DN A or R N A but never both.
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Components of Viruses
N ucleic acid core ( DN A or R N A)
Caspid : surrounding protein coat
Envelope : some viruses have thisadditional surrounding lipid
bilayer membrane
Virion : a complete virus particle
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Classfication of Viruses
H istorically, virologists classified viruses by type of host or the host structures they affected:-
Bacterophages: infect bacterial cellsPlant viruses : infect plant cells
Animal virus are subgrouped by the tissues they
attack:i. D ermotropic : if they infect the skinii. N eurotropic : if they infect nerve tissues
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Classfication of Viruses
Classified based on:-i. Type and structure of their nucleic acidsii. Method of replicationiii. H ost rangeiv. Other physical and chemical
characteristics
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Types of Viruses
Papovavirus:eg:- H uman Papilloma Virus ( H PV).
Retrovirus:eg:- H uman I mmunodeficiency Virus
(H I V).H erpesvirus:
eg:- Cytomegalovirus (CMV).- H erpes Simplex Virus ( H SV).
Etc
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P apovavirus.
Eg : H uman Papilloma Virus ( H PV).Types strain infection human
- type 16,18,31,33,35
Causes warts, including genital wartsOccurs in cervix genital tract
- transformation- vagina
- vulvaCell that infected:-- endocervical cell- metaplastic cell- squamous cell
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P apovavirus.
General symptoms :- Warts on the skin (face, hands, legs, feet) may be
itchy or slightly tender,- but are often asymptomatic.
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H uman P apilloma Virus ( HP V).
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H erpesvirus:
Eg: H erpes Simplex Virus ( H SV).Types of strain that infecting human:
- type 1
- type 2 (can caused cancer)occur in cervix genital tract:
- L abia- Clitoris- Vagina- Cervix
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H erpesvirus
General symptoms :- intense itching- burning sensation
- pain
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H erpes Simplex Virus ( H SV)
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Scheme of H SV
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H erpesvirus
eg: Cytomegalovirus (CMV).Occur in:
- endocervical endometrium
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Cytomegalovirus (CMV)
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Scheme of CMV
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Retrovirus
eg: H uman I mmunodeficiency Virus ( H I V)immune system begin to failleading to life-threatening oppurtunistic infection.
types:- H I V 1- H I V 2
transmission:- sexual relationship- blood- multiple infection
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Retrovirus
the clinical course of infection:H I V infection 4 stages
I ncubation period
Acute infectionL atency stage
A ID S
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H uman Immunodeficienc y Virus ( H IV)
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End~~Prepared by:
N uraldayana D aud 3071025381D ip. Tek. Makmal Perubatan
Siti Munirah I smail 3071004821D ip. Tek. Makmal Perubatan
Ros Farhana Rosli 3071025991D ip. Tek. Makmal Perubatan
N urul Ezzati Md Esa 3071025541D ip. Tek. Makmal Perubatan
N urul Aini Abu H assan Sheiri 3071025641D ip. Tek. Makmal Perubatan
Suindah N ordin 3071025881D ip. Tek. Makmal Perubatan
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