FMD in SE Asia and China · Cambodia, Laos, Malaysia, Myanmar, the Philippines, Thailand and...

Yu Qiu

OIE SRR-SEA

Project Officer

FMD in SE Asia and China

Outline

Introduction of SEACFMD

FMD regional situation

SEACFMD control measures

Outline

• SEACFMD Campaign History

• Roadmap and main activities

• FMD Surveillance

Outline

• SEAFMD established (Regional Coordination Unit), comprising Cambodia, Laos, Malaysia, Myanmar, the Philippines, Thailand and Vietnam.

• Indonesia (FMD free country) became a member.

• SEACFMD - China, Singapore, and Brunei joined;

OIE SRR-SEA founded.

• Mongolia jointed in 2016.

SEACFMD Campaign

Outline

International

Coordination

Program

Management

Private Sector

Surveillance, Diagnosis

and Control

Public Awareness

Policy, Legislation,

Zoning

Capacity Building

PCP-FMD

Outline

Surveillance database

WAHIS ARAHIS

Promote disease reporting and information sharing!

Regular meetings for information exchange

22nd SEACFMD Sub-CommissionChiang Rai, March 2016

Workshop on National FMD PlansNay Pyi Taw, Myanmar, Sep 2015

Outline

FMD Regional Situation

• FMDVs in the region

• FMD Transboundary nature

• FMD Outbreak distribution

• Regional dispersion of FMD

Outline

• Transboundary nature

• Outbreak distribution

• Regional dispersion

FMDVs in the region

Virus Pool 1

O• Mya-98

• Panasia

• Cathay

A• Sea-97

Asia 1Last detected in

SEA in 2007 and

in China in 2009

Outline

O/SEA/Mya-98

2010-2011

O/SEA/Mya-98

2010-2011

O/ME-SA/PanAsia

O/Cathay

A/Asia/SEA-97

2008-2009

A/Asia/SEA-97

2008-2009

A/Asia/SEA-97

2013-2014

G2 clade

Serotype Asia 1

Before 1996

Serotype Asia 1

2005-2007

No outbreaks after 2010

Outline

Distribution of FMD outbreaks, 2015

348 outbreaks in total

Cattle

Buffalo

Typing of FMDVs, 2015

O/ME-SA/Ind-2001d strain

South Asia origin, never in SEA previously

O/NEP/15/2013 (KM921857)

O/NEP/18/2013 (KM921860)

O/NEP/9/2014 (KM921868)

O/NEP/4/2014 (KM921863)

O/NEP/5/2014 (KM921864)

O/NEP/7/2014 (KM921866)

O/NEP/8/2014 (KM921867)

O/UAE/1/2014 (KM921877)

O/UAE/2/2014 (KM921878)

O/BAR/5/2015

O/BAR/2/2015

O/BAR/8/2015

O/BAR/12/2015

O/BAR/3/2015

O/BAR/4/2015

O/IND222/2013* (KM264364)

O/NEP/6/2013 (KM921854)

O/IND189/2013* (KM264361)

O/SRL/1/2013

O/SRL/2/2013

O/NEP/11/2013 (KM921855)

O/NEP/12/2013 (KM921856)

O/NEP/3/2013 (KM921853)

O/IND205/2013* (KM264362)

O/NEP/6/2014 (KM921865)

O/IND219/2013* (KM264363)

O/NEP/1/2014 (KM921861)

O/NEP/2/2014 (KM921862)

O/SRL/3/2014

O/SRL/15/2014

O/SRL/17/2014

O/SRL/27/2014

O/SRL/6/2014

O/SRL/5/2014

O/SRL/1/2014

O/SRL/9/2014

O/SRL/2/2014

O/SRL/11/2014

O/SRL/16/2014

O/SRL/35/2014

O/SRL/28/2014

O/SRL/34/2014

O/SRL/8/2014

O/SRL/7/2014

O/SRL/29/2014

O/SRL/30/2014

O/SRL/31/2014

O/SRL/32/2014

O/BAR/13/2015

O/BAR/14/2015

O/BAR/15/2015

O/LAO/3/2015

O/LAO/4/2015

O/LAO/2/2015

O/LAO/5/2015

O/DakLak/VIT/15-16451 B (RAHO6)

O/NinhThuan/VIT/15-19350 (RAHO6)

O/DakNong/VIT/15-17867 (RAHO6)

O/DakNong/VIT/15-17867 BHK2 (RAHO6)

O/BHU/1/2013 (KM921828)

O/NEP/16/2012 (KM921851)

O/IND50/2013* (KM264358)

O/NEP/11/2012 (KM921849)

O/NEP/13/2012 (KM921850)

O/NEP/10/2012 (KM921848)

O/NEP/16/2013 (KM921858)

O/NEP/17/2013 (KM921859)

O/IND127/2013* (KM264359)

O/SAU/2/2014

O/SAU/3/2014

O/SAU/1/2014 (KM921875)

O/IND179/2013* (KM264357)

O/SAU/6/2013 (KM921872)

O/SAU/7/2013 (KM921873)

O/SAU/8/2013 (KM921874)

O/SAU/3/2013 (KM921870)

O/SAU/1/2013 (KM921869)

O/SAU/4/2013 (KM921871)

O/IND52/2013* (KM264360)

O/LIB/16/2013 (KM921839)

O/LIB/22/2013 (KM921841)

O/LIB/1/2013 (KM921829)

O/LIB/4/2013 (KM921832)

O/LIB/5/2013 (KM921833)

O/LIB/7/2013 (KM921835)

O/LIB/11/2013 (KM921836)

O/LIB/12/2013 (KM921837)

O/LIB/13/2013 (KM921838)

O/LIB/17/2013 (KM921840)

O/LIB/2/2013 (KM921830)

O/LIB/3/2013 (KM921831)

O/LIB/6/2013 (KM921834)

O/IND/8/2010* (KC506452)

O/ORKo0810/IND/2010 (JX070621)

O/IND/160/2011* (KC506499)

O/IND/161/2011* (KC506500)

O/IND/11/2010* (KC506453)

O/UPMe1009/IND/2009 (JX070610)

O/BAN/9/2009 (HQ630681)

O/BHU/25/2009 (KM921825)

O/BHU/26/2009 (KM921826)

O/BHU/23/2009 (KM921824)

O/IND/32/2012* (KC506511)

O/IND/27/2010* (KC506454)

O/IND/31/2010* (KC506457)

O/IND/104/2010* (KC506467)

O/BHU/2/2009 (KM921813)

O/BHU/4/2009 (KM921815)

O/BHU/5/2009 (KM921816)

O/BHU/6/2009 (KM921817)

O/BHU/18/2009 (KM921822)

O/IND/148/2010* (KC506474)

O/IND/182/2010* (KC506478)

O/NEP/5/2010 (KM921843)

O/NEP/6/2010 (KM921844)

O/NEP/17/2010 (KM921845)

O/IND/181/2010* (KC506477)

O/IND/29/2010* (KC506455)

O/BHU/9/2009 (KM921819)

O/BHU/10/2009 (KM921820)

O/BHU/8/2009 (KM921818)

O/NEP/3/2010

O/IND/102/2010* (KC506466)

O/IND/30/2010* (KC506456)

O/BAN/26/2009 (HQ630687)

O/BAN/27/2009 (HQ630688)

O/BHU/19/2009 (KM921823)

O/IND/132/2010* (KC506472)

O/IND/27/2012* (KC506510)

Ind-2001d

PanAsia O/UKG/35/2001 (AJ539141)

O/IND/53/79 (AF292107)

O/IND/R2/75* (AF204276)

O1/Manisa/TUR/69 (AY593823)71

Trans-reginal spread of FMDV O/ME-SA/Ind-2001d in 2015

Significant epidemiological change

Importation of Indian Buffalo products?

O/NEP/15/2013 (KM921857)

O/NEP/18/2013 (KM921860)

O/NEP/9/2014 (KM921868)

O/NEP/4/2014 (KM921863)

O/NEP/5/2014 (KM921864)

O/NEP/7/2014 (KM921866)

O/NEP/8/2014 (KM921867)

O/UAE/1/2014 (KM921877)

O/UAE/2/2014 (KM921878)

O/BAR/5/2015

O/BAR/2/2015

O/BAR/8/2015

O/BAR/12/2015

O/BAR/3/2015

O/BAR/4/2015

O/IND222/2013* (KM264364)

O/NEP/6/2013 (KM921854)

O/IND189/2013* (KM264361)

O/SRL/1/2013

O/SRL/2/2013

O/NEP/11/2013 (KM921855)

O/NEP/12/2013 (KM921856)

O/NEP/3/2013 (KM921853)

O/IND205/2013* (KM264362)

O/NEP/6/2014 (KM921865)

O/IND219/2013* (KM264363)

O/NEP/1/2014 (KM921861)

O/NEP/2/2014 (KM921862)

O/SRL/3/2014

O/SRL/15/2014

O/SRL/17/2014

O/SRL/27/2014

O/SRL/6/2014

O/SRL/5/2014

O/SRL/1/2014

O/SRL/9/2014

O/SRL/2/2014

O/SRL/11/2014

O/SRL/16/2014

O/SRL/35/2014

O/SRL/28/2014

O/SRL/34/2014

O/SRL/8/2014

O/SRL/7/2014

O/SRL/29/2014

O/SRL/30/2014

O/SRL/31/2014

O/SRL/32/2014

O/BAR/13/2015

O/BAR/14/2015

O/BAR/15/2015

O/LAO/3/2015

O/LAO/4/2015

O/LAO/2/2015

O/LAO/5/2015

O/DakLak/VIT/15-16451 B (RAHO6)

O/NinhThuan/VIT/15-19350 (RAHO6)

O/DakNong/VIT/15-17867 (RAHO6)

O/DakNong/VIT/15-17867 BHK2 (RAHO6)

O/BHU/1/2013 (KM921828)

O/NEP/16/2012 (KM921851)

O/IND50/2013* (KM264358)

O/NEP/11/2012 (KM921849)

O/NEP/13/2012 (KM921850)

O/NEP/10/2012 (KM921848)

O/NEP/16/2013 (KM921858)

O/NEP/17/2013 (KM921859)

O/IND127/2013* (KM264359)

O/SAU/2/2014

O/SAU/3/2014

O/SAU/1/2014 (KM921875)

O/IND179/2013* (KM264357)

O/SAU/6/2013 (KM921872)

O/SAU/7/2013 (KM921873)

O/SAU/8/2013 (KM921874)

O/SAU/3/2013 (KM921870)

O/SAU/1/2013 (KM921869)

O/SAU/4/2013 (KM921871)

O/IND52/2013* (KM264360)

O/LIB/16/2013 (KM921839)

O/LIB/22/2013 (KM921841)

O/LIB/1/2013 (KM921829)

O/LIB/4/2013 (KM921832)

O/LIB/5/2013 (KM921833)

O/LIB/7/2013 (KM921835)

O/LIB/11/2013 (KM921836)

O/LIB/12/2013 (KM921837)

O/LIB/13/2013 (KM921838)

O/LIB/17/2013 (KM921840)

O/LIB/2/2013 (KM921830)

O/LIB/3/2013 (KM921831)

O/LIB/6/2013 (KM921834)

O/IND/8/2010* (KC506452)

O/ORKo0810/IND/2010 (JX070621)

O/IND/160/2011* (KC506499)

O/IND/161/2011* (KC506500)

O/IND/11/2010* (KC506453)

O/UPMe1009/IND/2009 (JX070610)

O/BAN/9/2009 (HQ630681)

O/BHU/25/2009 (KM921825)

O/BHU/26/2009 (KM921826)

O/BHU/23/2009 (KM921824)

O/IND/32/2012* (KC506511)

O/IND/27/2010* (KC506454)

O/IND/31/2010* (KC506457)

O/IND/104/2010* (KC506467)

O/BHU/2/2009 (KM921813)

O/BHU/4/2009 (KM921815)

O/BHU/5/2009 (KM921816)

O/BHU/6/2009 (KM921817)

O/BHU/18/2009 (KM921822)

O/IND/148/2010* (KC506474)

O/IND/182/2010* (KC506478)

O/NEP/5/2010 (KM921843)

O/NEP/6/2010 (KM921844)

O/NEP/17/2010 (KM921845)

O/IND/181/2010* (KC506477)

O/IND/29/2010* (KC506455)

O/BHU/9/2009 (KM921819)

O/BHU/10/2009 (KM921820)

O/BHU/8/2009 (KM921818)

O/NEP/3/2010

O/IND/102/2010* (KC506466)

O/IND/30/2010* (KC506456)

O/BAN/26/2009 (HQ630687)

O/BAN/27/2009 (HQ630688)

O/BHU/19/2009 (KM921823)

O/IND/132/2010* (KC506472)

O/IND/27/2012* (KC506510)

Ind-2001d

PanAsia O/UKG/35/2001 (AJ539141)

O/IND/53/79 (AF292107)

O/IND/R2/75* (AF204276)

O1/Manisa/TUR/69 (AY593823)71

Trans-reginal spread of FMDV O/ME-SA/Ind-2001d in 2015

• Outbreaks due to serotype A FMDVs during Aug-Sep 2015

• A/ASIA/Sea-97 strain

• Detected in Myanmar for the 1st

time in 5 years

• 99.8% identity in VP1 compared to isolates from China and Russia in 2013 and Thai isolates in 2014-15

Isolation of Serotype A viruses in Myanmar in 2015

Information till July 21, 2016

Ongoing reporting/serotyping

Outline

• Thailand• Lao PDR• Cambodia• Vietnam

Regional dispersion of FMDVs

O/SEA/MYA-98

O/MYA-98 Cluster 1

Jan-Jun 2014

O/MYA-98 Cluster 1

Jul-Dec 2014

O/MYA-98 Cluster 1

Jan-Jun 2015

A/Asia/SEA-97

A/SEA-97 Cluster 4

Jan-Jun 2014

A/SEA-97 Cluster 4

Jul-Dec 2014

A/SEA-97 Cluster 4

Jan-Jun 2015

Well Aligned with Cattle Movement Pathways in SEA

Bangladesh

Myanmar

ThailandLao PDR

Cambodia

Viet Nam

Outline

• Vaccination campaign

• Animal movement management

Outline

Myanmar cattle & buffalo populationapprox 16 million

Lao PDR cattle & buffalo populationapprox 6 million

approx 210,000 protected

approx 240,000 protected

Approximately 1 million large ruminantsare moving through SE Asia into Chinaand Vietnam annually

Animal Movement Study, 2015Approximately 1 million large ruminantsare moving through SE Asia into Chinaand Vietnam annually

Status (Central Myanmar)

Central Myanmar FMD Vaccination Projects, 2015 and 2016

o February and March 2015:

o 18 Townships targeted in Sagaing and Mandalay Regions

o 1127 villages vaccinated

o Benefiting >54,000 owners

o >210,000 animals vaccinated 2x

o March 2016

o Third vaccinations in the above

villages

Vaccinated Villages 2015

Outbreaks & vaccinated villages

• Vaccinated villages (1127)• Outbreak villages (81/210)• Outbreaks in vaccinated villages (14)

Status (northern Lao PDR)

Northern Lao PDR FMD Project, 2014-2016

o Follows the SGF projects in 2012 & 2013

o Vaccinations commenced September 2014

o Continue to June 2016 (breaks July/Aug during rainy season)

o 10 Provinces in northern Lao PDR

o 34 Districts (27 classified as high risk or hot spot)

o 1,081 villages

o Benefiting >120,000 owners

o Expected approx 244,000 animals vaccinated 3x by June 2016

FMD vaccination target villagesStarting from 2014

FMD Outbreaks during 2014-2015ARAHIS

No outbreaks detected in northern Lao PDR since May 2013

Outbreaks & vaccinated villages

Outline

Destination Country Official Protocol

ChinaImport Permit required. Imports from FMD-endemic countries are not approved.

VietnamSlaughter only. Import Permit required (?). Pre-entry Quarantine. Post-entryQuarantine 15 days. FMD & HS vaccination during post-entry Q. Test during post-entry Q for TB, Lepto, Brucella, with –ve results.

Thailand (General)Cattle/Buffalo Breeder. Import Permit required. Imports from FMD-endemic countries are not approved.

Thailand (ex Myanmar*)Import Permit required (?). Post-entry Quarantine 21 days. FMD vaccination during post-entry Q.

MalaysiaFeeder/Slaughter. Pre-entry Quarantine 10 days. Tested HS & JD –ve. Farm certified free from Brucellosis, and vaccinated pre-export. Post-entry Quarantine 15 days. FMD vaccination and NSP –ve during post-entry Q.

Cambodia Import conditions not known.

Laos Import Permit required. Specific import conditions not known.

Myanmar Import conditions not known

* Note: Exports from Myanmar are not officially approved.

Current process for a trader to move livestock legally across GMS+ borders

o Regional FMD epidemiologic situation is dynamic and complex

-> close monitoring of FMD outbreaks combined with genetic

and antigenic analysis of FMDVs -> developing control

measures

o Regional disease dissemination pathways are in line with animal

movement pathways -> strong official controls on cross-border

animal movements, plus enhanced multinational cooperation

o Promising outcomes from targeted vaccination programmes ->

continued and expanded vaccination campaign is needed

Summary

Thank you for your attention!

FMD in SE Asia and China · Cambodia, Laos, Malaysia, Myanmar, the Philippines, Thailand and...

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