CELL CYCLE AND CANCER. - Cell Division Mitosis During mitosis, the cell’s nucleus divides into two...

CELL CYCLE

AND

CANCER

- Cell Division

Mitosis• During mitosis, the cell’s nucleus divides

into two new nuclei. One copy of the DNA is distributed into each of the two daughter cells.

- Cell DivisionThe Cell Cycle

Length of the Cell CycleHow long does it take for a

cell to go through one cell

cycle? It all depends on the

cell. A human liver cell, for

example, completes one

cell cycle in about 22

hours, as shown in the

graph. Study the graph and

then answer the following

questions.

- Cell Division

Length of the Cell Cycle

–The longest curved arrow represents the cell’s interphase; the shortest represents cytokinesis; and the middle one represents mitosis.

• Reading Graphs:

– What do the three curved arrows outside the circle represent?

- Cell Division

Length of the Cell Cycle

– Interphase

• Reading Graphs:

• In what stage of the cell cycle is the wedge representing growth?

- Cell Division

Length of the Cell Cycle

–10 hours

• Interpreting Data:

– In human liver cells, how long does it take DNA replication to occur?

Length of the Cell Cycle

– Interphase

• Drawing Conclusions:

– In human liver cells, what stage in the cell cycle takes the longest time?

- Cell Division

- Cell DivisionStructure of DNA

• The DNA molecule is shaped like a twisted ladder.

• How do the Nitrogen bases pair up?• Adenine – Thymine• Cytosine - Guanine

- Cell DivisionReplication of DNA• What is it?

• When DNA make exact copy of itself

• Do the nitrogen bases have to match up?

• YES!!

• How?

• Adenine – Thymine

• Cytosine - Guanine

SequencingCan you name the stages and phases of

Cell Cycle?

The Cell Cycle

Cell grows, makes a copy of DNA.

Chromosomes and spindle fibers form;

nuclear envelope breaks down.

Chromosomes line up across the center and

attach to a spindle fiber.

Centromeres split; chromatids separate and move to opposite ends.

Chromosomes stretch out; new nuclear envelope forms

around chromosomes.

Cell pinches in two; each daughter cell has same number

of identical chromosomes.

Interphase

Mitosis: Prophase

Mitosis: Metaphase

Mitosis: Anaphase

Mitosis: Telophase

Cytokinesis

What Is Cancer?• Let’s find out

• You will work in groups of 3

• Each group member will learn and then teach

specific information about Cancer

to the other team mates!

• 1st member will teach: WHAT IS CANCER

• 2nd member: TREATING CANCER

• 3rd member: CANCER PREVENTION

• Each member will take notes

• Finally everyone will have to answer 3 specific

questions – we will review them!!

- CancerWhat Is Cancer?