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CELL CYCLE
AND
CANCER
- Cell Division
Mitosis• During mitosis, the cell’s nucleus divides
into two new nuclei. One copy of the DNA is distributed into each of the two daughter cells.
- Cell DivisionThe Cell Cycle
Length of the Cell CycleHow long does it take for a
cell to go through one cell
cycle? It all depends on the
cell. A human liver cell, for
example, completes one
cell cycle in about 22
hours, as shown in the
graph. Study the graph and
then answer the following
questions.
- Cell Division
Length of the Cell Cycle
–The longest curved arrow represents the cell’s interphase; the shortest represents cytokinesis; and the middle one represents mitosis.
• Reading Graphs:
– What do the three curved arrows outside the circle represent?
- Cell Division
Length of the Cell Cycle
– Interphase
• Reading Graphs:
• In what stage of the cell cycle is the wedge representing growth?
- Cell Division
Length of the Cell Cycle
–10 hours
• Interpreting Data:
– In human liver cells, how long does it take DNA replication to occur?
Length of the Cell Cycle
– Interphase
• Drawing Conclusions:
– In human liver cells, what stage in the cell cycle takes the longest time?
- Cell Division
- Cell DivisionStructure of DNA
• The DNA molecule is shaped like a twisted ladder.
• How do the Nitrogen bases pair up?• Adenine – Thymine• Cytosine - Guanine
- Cell DivisionReplication of DNA• What is it?
• When DNA make exact copy of itself
• Do the nitrogen bases have to match up?
• YES!!
• How?
• Adenine – Thymine
• Cytosine - Guanine
SequencingCan you name the stages and phases of
Cell Cycle?
The Cell Cycle
Cell grows, makes a copy of DNA.
Chromosomes and spindle fibers form;
nuclear envelope breaks down.
Chromosomes line up across the center and
attach to a spindle fiber.
Centromeres split; chromatids separate and move to opposite ends.
Chromosomes stretch out; new nuclear envelope forms
around chromosomes.
Cell pinches in two; each daughter cell has same number
of identical chromosomes.
Interphase
Mitosis: Prophase
Mitosis: Metaphase
Mitosis: Anaphase
Mitosis: Telophase
Cytokinesis
What Is Cancer?• Let’s find out
• You will work in groups of 3
• Each group member will learn and then teach
specific information about Cancer
to the other team mates!
• 1st member will teach: WHAT IS CANCER
• 2nd member: TREATING CANCER
• 3rd member: CANCER PREVENTION
• Each member will take notes
• Finally everyone will have to answer 3 specific
questions – we will review them!!
- CancerWhat Is Cancer?