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CANCERFACTSHEETS:LIVERCANCER
Estimatedage-standardisedrates(World)intheworld(per100000)
Males Females IncidenceMortality
China
WHOWesternPacificRegion
Lessdevelopedregions
World
WHOAfricanRegion
UnitedStatesofAmerica
WHOEasternMediterraneanRegion
Moredevelopedregions
IARCMemberState(24countries)
EuropeanUnion(EU-28)
WHORegionoftheAmericas
WHOSouth-EastAsiaRegion
WHOEuropeanRegion
India
20 0 2040 40
Ataglance
Livercanceristhefifthmostcommoncancerinmenandtheninthmostcommoncancerinwomen,anditislargelyaproblemofthelessdevelopedregions.In2012,worldwide,thereareestimatedtohavebeen782000newcases,with83%ofthesecasesoccurringinlessdevelopedregions(50%inChinaalone).Ofthistotalnumberofincidentcases,554000occurredinmen(accountingfor7.5%ofallincidentcancercasesinmen)and228000occurredinwomen(accountingfor3.4%ofallincidentcancercasesinwomen).Inmen,thehighestestimated2012age-standardizedincidencerates(per100000population)areineasternandsouth-easternAsia(with31.9and22.2cases,respectively).IntermediateratesareestimatedinsouthernEurope(9.5cases)andNorthAmerica(9.3cases),andthelowestestimatedratesareinnorthernEurope(4.6cases)andsouth-centralAsia(3.7cases).Inwomen,theincidenceisgenerallymuchlower,withthehighestestimated2012ratesineasternAsiaandwesternAfrica(10.2and8.1cases,respectively)andthelowestinnorthernEurope(1.9cases)andMicronesia(1.6cases).
Livercanceristhesecondmostcommoncauseofdeathfromcancerworldwide,estimatedtohavebeenresponsiblefornearly746000deathsin2012(9.1%ofallcancerdeathsthatyear).Theprognosisforlivercancerisverypoor(withanoverallratioofmortalitytoincidenceof0.95),sothegeographicalpatternsinincidenceandmortalityareverysimilar.
Estimatedincidence,mortalityandprevalence(5years)worlwidein2012
Estimatednumbers Males Females Bothsexes
Cases Deaths 5-year-prev Cases Deaths 5-year-prev Cases Deaths 5-year-prev
World 554369 521041 15296119 228082 224492 17159060 782451 745533 32455179
Moredevelopedregions 92018 80425 8549600 42284 42652 8273689 134302 123077 16823289
Lessdevelopedregions 462351 440616 6746519 185798 181840 8885371 648149 622456 15631890
WHOAfricanRegion 24791 23758 467820 14032 13403 895005 38823 37161 1362825
WHORegionoftheAmericas 40288 34704 3843203 22872 23180 4114742 63160 57884 7957945
WHOEasternMediterraneanRegion 19844 18893 461190 9523 9056 732587 29367 27949 1193777
WHOEuropeanRegion 47155 44087 4791316 23421 24959 4909685 70576 69046 9701001
WHOSouth-EastAsiaRegion 54678 52351 1237475 25284 24395 2040925 79962 76746 3278400
WHOWesternPacificRegion 367572 347208 4492687 132934 129484 4463736 500506 476692 8956423
IARCMemberState(24countries) 120066 104105 9192817 56263 54741 9401981 176329 158846 18594796
UnitedStatesofAmerica 22541 16863 2402172 7908 7449 2373019 30449 24312 4775191
China 293318 281802 2495611 101452 101401 2549427 394770 383203 5045038
India 17236 16755 664538 10180 10008 1125960 27416 26763 1790498
EuropeanUnion(EU-28) 35893 31881 3692805 15892 16571 3463915 51785 48452 7156720
Estimatedage-standardizedrates(World)ofincidencecases,males,livercancer,worldwidein2012
≥97.8
7.7–12.6
5.6–7.7
4.0–5.6
<1.2
Nodata
Notapplicable
Allrightsreserved.ThedesignationsemployedandthepresentationofthematerialinthispublicationdonotimplytheexpressionofanyopinionwhatsoeveronthepartoftheWorldHealthOrganization/InternationalAgencyforResearchonCancerconcerningthelegalstatusofanycountry,territory,cityorareaorofitsauthorities,orconcerningthedelimitationofitsfrontiersorboundaries.Dottedanddashedlinesonmapsrepresentapproximateborderlinesforwhichtheremaynotyetbefullagreement.
Datasource:GLOBOCAN2012Graphproduction:IARC(http://gco.iarc.fr/today)WorldHealthOrganization
©InternationalAgencyforResearchonCancer2016
Estimatedage-standardizedrates(World)ofincidencecases,males,livercancer,worldwidein2012
*RegionaldataNORDCAN(www.ancr.nu)ECO(eco.iarc.fr)England:www.ons.gov.uk
*RegionaldataCI5.iarc.fr
*RegionaldataCI5.iarc.frAustralia:www.aih.gov.auNewZealand:wwww.health.govt.nzUSA:seer.cancer.gov
Estimatedage-standardizedrates(World)ofdeaths,males,livercancer,worldwidein2012
≥89.3
7.2–12.5
5.5–7.2
4.1–5.5
<1.1
Nodata
Notapplicable
Allrightsreserved.ThedesignationsemployedandthepresentationofthematerialinthispublicationdonotimplytheexpressionofanyopinionwhatsoeveronthepartoftheWorldHealthOrganization/InternationalAgencyforResearchonCancerconcerningthelegalstatusofanycountry,territory,cityorareaorofitsauthorities,orconcerningthedelimitationofitsfrontiersorboundaries.Dottedanddashedlinesonmapsrepresentapproximateborderlinesforwhichtheremaynotyetbefullagreement.
Datasource:GLOBOCAN2012Graphproduction:IARC(http://gco.iarc.fr/today)WorldHealthOrganization
©InternationalAgencyforResearchonCancer2016
Estimatedage-standardizedrates(World)ofincidencecases,females,livercancer,worldwidein2012
≥61.1
3.7–6.4
2.6–3.7
1.9–2.6
<0.00
Nodata
Notapplicable
Allrightsreserved.ThedesignationsemployedandthepresentationofthematerialinthispublicationdonotimplytheexpressionofanyopinionwhatsoeveronthepartoftheWorldHealthOrganization/InternationalAgencyforResearchonCancerconcerningthelegalstatusofanycountry,territory,cityorareaorofitsauthorities,orconcerningthedelimitationofitsfrontiersorboundaries.Dottedanddashedlinesonmapsrepresentapproximateborderlinesforwhichtheremaynotyetbefullagreement.
Datasource:GLOBOCAN2012Graphproduction:IARC(http://gco.iarc.fr/today)WorldHealthOrganization
©InternationalAgencyforResearchonCancer2016
Estimatedage-standardizedrates(World)ofincidencecases,females,livercancer,worldwidein2012
*RegionaldataNORDCAN(www.ancr.nu)ECO(eco.iarc.fr)England:www.ons.gov.uk
*RegionaldataCI5.iarc.fr
*RegionaldataCI5.iarc.frAustralia:www.aih.gov.auNewZealand:wwww.health.govt.nzUSA:seer.cancer.gov
Estimatedage-standardizedrates(World)ofdeaths,females,livercancer,worldwidein2012
≥54.1
3.8–6.3
2.6–3.8
1.9–2.6
<0.00
Nodata
Notapplicable
Allrightsreserved.ThedesignationsemployedandthepresentationofthematerialinthispublicationdonotimplytheexpressionofanyopinionwhatsoeveronthepartoftheWorldHealthOrganization/InternationalAgencyforResearchonCancerconcerningthelegalstatusofanycountry,territory,cityorareaorofitsauthorities,orconcerningthedelimitationofitsfrontiersorboundaries.Dottedanddashedlinesonmapsrepresentapproximateborderlinesforwhichtheremaynotyetbefullagreement.
Datasource:GLOBOCAN2012Graphproduction:IARC(http://gco.iarc.fr/today)WorldHealthOrganization
©InternationalAgencyforResearchonCancer2016
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