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CANCER FACT SHEETS: LIVER CANCER Estimated age-standardised rates (World) in the world (per 100 000) Males Females Incidence Mortality China WHO Western Pacific Region Less developed regions World WHO African Region United States of America WHO Eastern Mediterranean Region More developed regions IARC Member State (24 countries) European Union (EU-28) WHO Region of the Americas WHO South-East Asia Region WHO European Region India 20 0 20 40 40 At a glance Liver cancer is the fifth most common cancer in men and the ninth most common cancer in women, and it is largely a problem of the less developed regions. In 2012, worldwide, there are estimated to have been 782 000 new cases, with 83% of these cases occurring in less developed regions (50% in China alone). Of this total number of incident cases, 554 000 occurred in men (accounting for 7.5% of all incident cancer cases in men) and 228 000 occurred in women (accounting for 3.4% of all incident cancer cases in women). In men, the highest estimated 2012 age-standardized incidence rates (per 100 000 population) are in eastern and south-eastern Asia (with 31.9 and 22.2 cases, respectively). Intermediate rates are estimated in southern Europe (9.5 cases) and North America (9.3 cases), and the lowest estimated rates are in northern Europe (4.6 cases) and south-central Asia (3.7 cases). In women, the incidence is generally much lower, with the highest estimated 2012 rates in eastern Asia and western Africa (10.2 and 8.1 cases, respectively) and the lowest in northern Europe (1.9 cases) and Micronesia (1.6 cases). Liver cancer is the second most common cause of death from cancer worldwide, estimated to have been responsible for nearly 746 000 deaths in 2012 (9.1% of all cancer deaths that year). The prognosis for liver cancer is very poor (with an overall ratio of mortality to incidence of 0.95), so the geographical patterns in incidence and mortality are very similar.

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Page 1: CANCER FACT SHEETS: LIVER CANCER · 2016-05-12 · Liver cancer is the fifth most common cancer in men and the ninth most common cancer in women, and it is largely a problem of the

CANCERFACTSHEETS:LIVERCANCER

Estimatedage-standardisedrates(World)intheworld(per100000)

Males Females IncidenceMortality

China

WHOWesternPacificRegion

Lessdevelopedregions

World

WHOAfricanRegion

UnitedStatesofAmerica

WHOEasternMediterraneanRegion

Moredevelopedregions

IARCMemberState(24countries)

EuropeanUnion(EU-28)

WHORegionoftheAmericas

WHOSouth-EastAsiaRegion

WHOEuropeanRegion

India

20 0 2040 40

Ataglance

Livercanceristhefifthmostcommoncancerinmenandtheninthmostcommoncancerinwomen,anditislargelyaproblemofthelessdevelopedregions.In2012,worldwide,thereareestimatedtohavebeen782000newcases,with83%ofthesecasesoccurringinlessdevelopedregions(50%inChinaalone).Ofthistotalnumberofincidentcases,554000occurredinmen(accountingfor7.5%ofallincidentcancercasesinmen)and228000occurredinwomen(accountingfor3.4%ofallincidentcancercasesinwomen).Inmen,thehighestestimated2012age-standardizedincidencerates(per100000population)areineasternandsouth-easternAsia(with31.9and22.2cases,respectively).IntermediateratesareestimatedinsouthernEurope(9.5cases)andNorthAmerica(9.3cases),andthelowestestimatedratesareinnorthernEurope(4.6cases)andsouth-centralAsia(3.7cases).Inwomen,theincidenceisgenerallymuchlower,withthehighestestimated2012ratesineasternAsiaandwesternAfrica(10.2and8.1cases,respectively)andthelowestinnorthernEurope(1.9cases)andMicronesia(1.6cases).

Livercanceristhesecondmostcommoncauseofdeathfromcancerworldwide,estimatedtohavebeenresponsiblefornearly746000deathsin2012(9.1%ofallcancerdeathsthatyear).Theprognosisforlivercancerisverypoor(withanoverallratioofmortalitytoincidenceof0.95),sothegeographicalpatternsinincidenceandmortalityareverysimilar.

Page 2: CANCER FACT SHEETS: LIVER CANCER · 2016-05-12 · Liver cancer is the fifth most common cancer in men and the ninth most common cancer in women, and it is largely a problem of the

Estimatedincidence,mortalityandprevalence(5years)worlwidein2012

Estimatednumbers Males Females Bothsexes

Cases Deaths 5-year-prev Cases Deaths 5-year-prev Cases Deaths 5-year-prev

World 554369 521041 15296119 228082 224492 17159060 782451 745533 32455179

Moredevelopedregions 92018 80425 8549600 42284 42652 8273689 134302 123077 16823289

Lessdevelopedregions 462351 440616 6746519 185798 181840 8885371 648149 622456 15631890

WHOAfricanRegion 24791 23758 467820 14032 13403 895005 38823 37161 1362825

WHORegionoftheAmericas 40288 34704 3843203 22872 23180 4114742 63160 57884 7957945

WHOEasternMediterraneanRegion 19844 18893 461190 9523 9056 732587 29367 27949 1193777

WHOEuropeanRegion 47155 44087 4791316 23421 24959 4909685 70576 69046 9701001

WHOSouth-EastAsiaRegion 54678 52351 1237475 25284 24395 2040925 79962 76746 3278400

WHOWesternPacificRegion 367572 347208 4492687 132934 129484 4463736 500506 476692 8956423

IARCMemberState(24countries) 120066 104105 9192817 56263 54741 9401981 176329 158846 18594796

UnitedStatesofAmerica 22541 16863 2402172 7908 7449 2373019 30449 24312 4775191

China 293318 281802 2495611 101452 101401 2549427 394770 383203 5045038

India 17236 16755 664538 10180 10008 1125960 27416 26763 1790498

EuropeanUnion(EU-28) 35893 31881 3692805 15892 16571 3463915 51785 48452 7156720

Page 3: CANCER FACT SHEETS: LIVER CANCER · 2016-05-12 · Liver cancer is the fifth most common cancer in men and the ninth most common cancer in women, and it is largely a problem of the

Estimatedage-standardizedrates(World)ofincidencecases,males,livercancer,worldwidein2012

≥97.8

7.7–12.6

5.6–7.7

4.0–5.6

<1.2

Nodata

Notapplicable

Allrightsreserved.ThedesignationsemployedandthepresentationofthematerialinthispublicationdonotimplytheexpressionofanyopinionwhatsoeveronthepartoftheWorldHealthOrganization/InternationalAgencyforResearchonCancerconcerningthelegalstatusofanycountry,territory,cityorareaorofitsauthorities,orconcerningthedelimitationofitsfrontiersorboundaries.Dottedanddashedlinesonmapsrepresentapproximateborderlinesforwhichtheremaynotyetbefullagreement.

Datasource:GLOBOCAN2012Graphproduction:IARC(http://gco.iarc.fr/today)WorldHealthOrganization

©InternationalAgencyforResearchonCancer2016

http://gco.iarc.fr/today
Page 4: CANCER FACT SHEETS: LIVER CANCER · 2016-05-12 · Liver cancer is the fifth most common cancer in men and the ninth most common cancer in women, and it is largely a problem of the

Estimatedage-standardizedrates(World)ofincidencecases,males,livercancer,worldwidein2012

*RegionaldataNORDCAN(www.ancr.nu)ECO(eco.iarc.fr)England:www.ons.gov.uk

*RegionaldataCI5.iarc.fr

*RegionaldataCI5.iarc.frAustralia:www.aih.gov.auNewZealand:wwww.health.govt.nzUSA:seer.cancer.gov

Page 5: CANCER FACT SHEETS: LIVER CANCER · 2016-05-12 · Liver cancer is the fifth most common cancer in men and the ninth most common cancer in women, and it is largely a problem of the

Estimatedage-standardizedrates(World)ofdeaths,males,livercancer,worldwidein2012

≥89.3

7.2–12.5

5.5–7.2

4.1–5.5

<1.1

Nodata

Notapplicable

Allrightsreserved.ThedesignationsemployedandthepresentationofthematerialinthispublicationdonotimplytheexpressionofanyopinionwhatsoeveronthepartoftheWorldHealthOrganization/InternationalAgencyforResearchonCancerconcerningthelegalstatusofanycountry,territory,cityorareaorofitsauthorities,orconcerningthedelimitationofitsfrontiersorboundaries.Dottedanddashedlinesonmapsrepresentapproximateborderlinesforwhichtheremaynotyetbefullagreement.

Datasource:GLOBOCAN2012Graphproduction:IARC(http://gco.iarc.fr/today)WorldHealthOrganization

©InternationalAgencyforResearchonCancer2016

http://gco.iarc.fr/today
Page 6: CANCER FACT SHEETS: LIVER CANCER · 2016-05-12 · Liver cancer is the fifth most common cancer in men and the ninth most common cancer in women, and it is largely a problem of the

Estimatedage-standardizedrates(World)ofincidencecases,females,livercancer,worldwidein2012

≥61.1

3.7–6.4

2.6–3.7

1.9–2.6

<0.00

Nodata

Notapplicable

Allrightsreserved.ThedesignationsemployedandthepresentationofthematerialinthispublicationdonotimplytheexpressionofanyopinionwhatsoeveronthepartoftheWorldHealthOrganization/InternationalAgencyforResearchonCancerconcerningthelegalstatusofanycountry,territory,cityorareaorofitsauthorities,orconcerningthedelimitationofitsfrontiersorboundaries.Dottedanddashedlinesonmapsrepresentapproximateborderlinesforwhichtheremaynotyetbefullagreement.

Datasource:GLOBOCAN2012Graphproduction:IARC(http://gco.iarc.fr/today)WorldHealthOrganization

©InternationalAgencyforResearchonCancer2016

http://gco.iarc.fr/today
Page 7: CANCER FACT SHEETS: LIVER CANCER · 2016-05-12 · Liver cancer is the fifth most common cancer in men and the ninth most common cancer in women, and it is largely a problem of the

Estimatedage-standardizedrates(World)ofincidencecases,females,livercancer,worldwidein2012

*RegionaldataNORDCAN(www.ancr.nu)ECO(eco.iarc.fr)England:www.ons.gov.uk

*RegionaldataCI5.iarc.fr

*RegionaldataCI5.iarc.frAustralia:www.aih.gov.auNewZealand:wwww.health.govt.nzUSA:seer.cancer.gov

Page 8: CANCER FACT SHEETS: LIVER CANCER · 2016-05-12 · Liver cancer is the fifth most common cancer in men and the ninth most common cancer in women, and it is largely a problem of the

Estimatedage-standardizedrates(World)ofdeaths,females,livercancer,worldwidein2012

≥54.1

3.8–6.3

2.6–3.8

1.9–2.6

<0.00

Nodata

Notapplicable

Allrightsreserved.ThedesignationsemployedandthepresentationofthematerialinthispublicationdonotimplytheexpressionofanyopinionwhatsoeveronthepartoftheWorldHealthOrganization/InternationalAgencyforResearchonCancerconcerningthelegalstatusofanycountry,territory,cityorareaorofitsauthorities,orconcerningthedelimitationofitsfrontiersorboundaries.Dottedanddashedlinesonmapsrepresentapproximateborderlinesforwhichtheremaynotyetbefullagreement.

Datasource:GLOBOCAN2012Graphproduction:IARC(http://gco.iarc.fr/today)WorldHealthOrganization

©InternationalAgencyforResearchonCancer2016

http://gco.iarc.fr/today

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