Basic Histological Layers 1. Mucosa b. Lamina …...Histology of the Digestive System Basic...

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Histology of the Digestive System

Basic Histological Layers1. Mucosa

a. Epitheliumb. Lamina Propriac. Muscularis Mucosae

2. Submucosaa. Submucosal plexus

“Plexus of Meissner”3. Muscularis

a. Myenteric plexus“Plexus of Auerbach

4. Serosa

Histology of the Mucosa

Simple ColumnarLarge Intestine

Nonkeratinized Stratified SquamousEsophagus

Nonkeratinized Stratified SquamousAnus

Simple ColumnarSmall Intestine

Simple ColumnarStomach

Nonkeratinized Stratified SquamousPharynx

Nonkeratinized Stratified SquamousMouth

EpitheliumOrgan

Histology of the Mucosa

L: Plicae circulares, Villi S: Crypts of Lieberkuhn, microvilli

Small Intestine

L: Haustra S: Intestinal glandsLarge Intestine

L: Rugae, S: gastric pitsStomach

noneEsophagus

Folds of the epitheliumOrgan

Histology of the Submucosa

Brunner’s glandsDuodenum

NoneLarge Intestine

Peyer’s PatchesIleum

NoneStomach

Submucosal mucous glandsEsophagus

Specialized structuresOrgan

Histology of the Muscularis

2, circular and longitudinalSmall Intestine

2, circular and longitudinalLarge Intestine

3, oblique, circular, and longitudinalStomach

2, circular and longitudinalEsophagus

Smooth muscle layersOrgan

Histology of the Serosa

Visceral Peritoneum Large Intestine

AdventitiaAnus

Visceral Peritoneum Small Intestine

Visceral Peritoneum Stomach

Adventitia due to the fact that the esophagus is not in a cavity

Esophagus

SerosaOrgan

Esophagus

Esophagus

Esophagus

Esophagus of cat

Stomach fundus Mucosa

1. Shallow gastric pits2. Simple branched tubular

glands3. Crowded glands with

minimal CT lamina propria

Stomach fundus Mucosa

Stomach fundus Mucosa

Stomach fundus Mucosa

Fundus Mucosa:Parietal acidophilic cells and chief basophilic cells

Stomach Pylorus Mucosa

Stratified sq epithelium

No Stratified sq epithelium

Small intestineVilli and crypts

TS view of the duodenumBrunner’s glands

Duodenum: Brunner’s glands

Ileum: Peyer’s patches

Ileum: Peyer’s patches

Appendix lymphoid follicles all around

lymphoid follicles all around, no villi

High power view of the colon demonstrating intestinal glands

Large Intestine

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