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Any device that analyzes a biological compound into a measurable signal
Composed of a bioreceptor, transducer, and an electronic peripheral
Bioreceptor: Part of device that interacts with a biological material to identify and interact with a target molecule
Transducer: Part of the device that turns the target molecule into a measured signal
Electronic Peripheral: Turns the measured signal into a graphical user interface (GUI) utilizing microprocessors
Enzymes, Antibodies, or nucleic acids.
Piezoelectric, Thermal, Electrochemical, and Optical
LED Display
Piezoelectric: crystal detector uses the change of frequency to calculate change in mass
Thermal: measures change in heat (exothermic, endothermic)
Electrochemical: (Amperometric, or potentiometric) uses electrodes to measure current
Optical: uses Surface Plasmon Resonance (SPR), or reflectance to identify various biological molecules
Measures Mass
Measures heat, requires large sample size, complicated devices
Amperometric are among the most common transducers for biosensors
Great for identifying antigens, or cancerous cells in a solution
Current Applications Lab-on-a-chip Pollutant Control Patient Diagnosis Detection of
harmful pathogens, bacteria, toxic compounds
Future Disposable Low Cost Increased
Sensitivity Improved
Microprocessors Multipurpose Environmental
friendly
1. Pohanka, Miroslave. "ElectrochemicalBiosensors – Principles and Applications."Journal of Applied Biomedicine (2008): 58-62.Web. 20 Nov. 2012.2. Mutharasan, Raj. "Biosensors." EngineeringBiotechnology. N.p., n.d. Web. 20 Nov. 2012.<http://www.gatewaycoalition.org/files/Hidden/sensr/ch1/1_1f.htm>.3. Kumar, Ashok. "Biosensors Based onPiezoelectric Crystal Detectors: Theory andApplication." Department of MechanicalEngineering and Center for MicroelectronicsResearch (2010): 1-6. Web.http://www.tms.org/pubs/journals/JOM/0010/Kumar/Kumar-0010.html4. Dey, D., and T. Goswami. "Optical
Biosensors:A Revolution Towards Quantum NanoscaleElectronics Device Fabrication." Journal ofBiomedicine and Biotechnology 2011.348218(2011): 0-7. Web. 20 Nov. 2012.<http://http://www.hindawi.com/journals/jbb/2011/348218/>.
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