Anthony Catalano

Any device that analyzes a biological compound into a measurable signal

Composed of a bioreceptor, transducer, and an electronic peripheral

Bioreceptor: Part of device that interacts with a biological material to identify and interact with a target molecule

Transducer: Part of the device that turns the target molecule into a measured signal

Electronic Peripheral: Turns the measured signal into a graphical user interface (GUI) utilizing microprocessors

Enzymes, Antibodies, or nucleic acids.

Piezoelectric, Thermal, Electrochemical, and Optical

LED Display

Piezoelectric: crystal detector uses the change of frequency to calculate change in mass

Thermal: measures change in heat (exothermic, endothermic)

Electrochemical: (Amperometric, or potentiometric) uses electrodes to measure current

Optical: uses Surface Plasmon Resonance (SPR), or reflectance to identify various biological molecules

Measures Mass

Measures heat, requires large sample size, complicated devices

Amperometric are among the most common transducers for biosensors

Great for identifying antigens, or cancerous cells in a solution

Current Applications Lab-on-a-chip Pollutant Control Patient Diagnosis Detection of

harmful pathogens, bacteria, toxic compounds

Future Disposable Low Cost Increased

Sensitivity Improved

Microprocessors Multipurpose Environmental

friendly

1. Pohanka, Miroslave. "ElectrochemicalBiosensors – Principles and Applications."Journal of Applied Biomedicine (2008): 58-62.Web. 20 Nov. 2012.2. Mutharasan, Raj. "Biosensors." EngineeringBiotechnology. N.p., n.d. Web. 20 Nov. 2012.<http://www.gatewaycoalition.org/files/Hidden/sensr/ch1/1_1f.htm>.3. Kumar, Ashok. "Biosensors Based onPiezoelectric Crystal Detectors: Theory andApplication." Department of MechanicalEngineering and Center for MicroelectronicsResearch (2010): 1-6. Web.http://www.tms.org/pubs/journals/JOM/0010/Kumar/Kumar-0010.html4. Dey, D., and T. Goswami. "Optical

Biosensors:A Revolution Towards Quantum NanoscaleElectronics Device Fabrication." Journal ofBiomedicine and Biotechnology 2011.348218(2011): 0-7. Web. 20 Nov. 2012.<http://http://www.hindawi.com/journals/jbb/2011/348218/>.