View
39
Download
4
Category
Preview:
Citation preview
WHY?
For well educated students
For teachers who know the ‘state of
the art’
For companies, to support in research
and innovation
Development of smart screeningssystems
antimicrobial/antifungal
– Medical
– Agro & Food
– other
C. elegans screeningssystem
– Medical (obesity)
– Safety/Toxicity
Oil from yeast
In cooperation with Wageningen UR
Companies: Nuplex, van Wijhe, Latexfalt,
Holland Colors, Parenco, Dyadic, MicCell, MVO
Biological screening systems Analytical chemistry Bio-informatics Molecular biology
PCR/qPCR
SDS-PAGE
LC-MS
HPLC
FPLC
GC
Fluorescence microscopy
Amphotericin
0
20000
40000
60000
80000
100000
120000
0:0
0
0:3
7
1:1
5
1:5
3
2:3
0
3:0
8
3:4
6
4:2
3
5:0
1
5:3
9
6:1
7
6:5
4
7:3
2
8:1
0
8:4
7
9:2
5
10:0
3
10:4
0
11:1
8
11:5
6
12:3
3
13:1
1
13:4
9
14:2
6
15:0
4
15:4
2
time (h)
Lu
min
escen
s
water
NaPb
DMSO 1:100
Amph 20 µM
Amph 10 µM
Amph 5 µM
Amph 2,5 µM
Amph 1 µM
Amph 0,5 µM
Amph 0,1 µM
Fermentation & downstream processing • From 1 to 20 L (E. coli, lactic acid bacteria, Bacillus,
Helicobacter, filamentous fungi, basidiomycetes,
yeast)
• Downstream processing
– IEX
– GPC
– Microfiltration
– Ultrafiltration
• Strain selection
• Genetic modification of m.o.
• AM-Pharma
• Aquamar
• Argos Oil
• Avatar Biotechnologies (USA)
• Avebe
• Basidiofactory
• Benilabs
• B.O.B.
• Cellution Biotech
• C4C
• Christian Hansen (DK)
• CSK Food Enrichment
• CU+TOP
• Cyto-Barr
• DMV International
• DSM
• Dyadic Nederland
• European Veterinary Laboratory
• Falco Diagnostics
• Filtex
• Innovative SeedTechnology
• TNO Quality of Life
• Koppert
• LabTie
• Meddens Diagnostics
• MicCell
• Micreos
• Nsure
• Nuplex
• NVWA
• NYtor
• Parenco
• Productschap Tuinbouw
• ProteoNic
• Quaker
• Rainbow Sustainable solutions
• RIVM
• Shell
• Uniqema/Croda
• Unilever
• Van Wijhe
• Vitaleech Bioscience
• Vivalt screening
• Xenikos
What do we offer?
- Contract research
- Cooperative research • Basidiofactory
• Vivalt screening
- Lab facilities • Basidiofactory
• Vivalt screening
- Workshops
APPLICATION DISCOVERY ANALYSIS PRODUCTION
What do companies bring?
- Knowledge/new developments
- Guest lectures
- Facility sharing
- Internships
APPLICATION DISCOVERY ANALYSIS PRODUCTION
Recommended