1 G. P. S. Raghava Institute of Microbial Technology, Chandigarh

1

G. P. S. Raghava

Institute of Microbial Technology, Chandigarh

2

Novelty Behind CRDD

• Compilation of resources (single platform)

• High priority to peer-review data

• Web Interface over libraries (e.g. R)

• Integration of chemo/pharma/bioinformatics

• User-friendly interfaces

• Support for multiple programming languages

• Award/Reward system

3

4

5

6

7

8

9

• Promoting Open Source for Drug Discovery(OSDD) • Bringing all experts on single plateform

– Diverse background of speakers (Computer Science to Pharma)

– Lectures covers wide range of topics (insilico drug discovery)• Informatics (Soft-computing, clusteing, Machine learning etc.)• Bioinformatics (annotation, protein modelling/docking, interaction)• Chemoinformatics (structure, QSAR based inhibitors)• Pharmacoinformatics• Clinical informatics

10

• Total participants ~170• Speakers ~40• OSDD Fellowships ~15• Diverse Backgrounds

• ~ 110 students (M.Sc, B.Tech, MBA, M.Pharma,MCA,MBBS)• ~ 40 Research scholars • ~ 20 faculty • Biology, bioinformatics, chemistry, clinical, medicine, computer

science, Pharmacology etc.

11

Ongoing Works at IMTECH

12

13

14

15

Sort Term Future Plan

• Prediction of protein-protein interaction in Mtb proteins

• Experimental validation of interaction

• A database of natural drug products

• Computation of structure descriptor of drug molecules

• Biobox or Bio cluster service to OSDD community

• Organism specific databases: Malaria and Mtb

• Virtual jobs particularly for women's

16